194results about How to "Improve regenerative ability" patented technology

The invention provides an amine low-water-content absorbent for capturing carbon dioxide and application of the amine low-water-content absorbent. The amine low-water absorbent comprises, by mass, 20%-50% of an absorbent main agent, 35%-70% of an auxiliary solvent and 2%-20% of water, and the range of a solvent effect factor delta of the amine low-water absorbent is 0.28-0.32. According to the method, the composition of the water-less absorbent is screened and optimized through a solvent effect factor formula, the amine water-less absorbent which is easy to desorb, low in regeneration energy consumption and low in viscosity characteristic is obtained, and wide application of the amine water-less absorbent in a carbon capture technology is promoted.

The invention provides a hydroxytyrosol supramolecular compound and a preparation method and application thereof, and belongs to the technical field of cosmetics and biological medicine, the supramolecular compound comprises the following chemical components by mass: 0.01-10% of hydroxytyrosol, 2-45% of an amino acid compound, 2-20% of alpha hydroxy acid, 2-30% of urea, and 15-92% of water. The supramolecular compound can promote transdermal delivery of hydroxytyrosol and maintain the biological activity of hydroxytyrosol, shows high biocompatibility, and can be applied to product development in the antibacterial field, the regeneration field and the anti-aging field.

The invention relates to bamboo fiber-based food fresh-keeping packaging paper and a preparation method thereof. The preparation method of the bamboo fiber-based food fresh-keeping packaging paper comprises the following steps: respectively grinding bleached sulfate tender moso bamboo fibers and moso bamboo root fibers, and dispersing and mixing to obtain NBF / BRF mixed pulp; then adding the modified moso bamboo cellulose nanocrystals to obtain NBF / BRF / BNC composite slurry; making paper with pulp, forming, dehydrating and drying to obtain a bamboo paper sample A, uniformly spraying bamboo vinegar on the outer surface of the bamboo paper sample A, and finally performing hot pressing and drying to obtain the bamboo fiber-based food fresh-keeping packaging paper. Bamboo fiber raw materials with different characteristics are used for preparing the packaging paper for food preservation, the bamboo fiber-based food packaging paper is endowed with excellent mechanical strength, barrier property, hydrophobic property and antibacterial and mildew-proof capabilities, and the bamboo fiber-based food packaging paper can be used in the field of packaging materials for fruit and vegetable preservation.

The invention belongs to the technical field of new energy solid oxide fuel cells, and particularly relates to a recoverable PCFC cathode material and a preparation method and a recovery method thereof. The invention provides a novel recoverable PCFC cathode material as well as a preparation method and a recovery method thereof in order to solve the technical problems that the performance of a cell is degraded due to the fact that an existing cathode material of a proton ceramic fuel cell (PCFC) is poor in matching degree with a common electrolyte material and is easy to separate from the common electrolyte material, and a complete PCFC cathode recovery technology is still lacked, and provides a novel recoverable PCFC cathode material and a preparation method and a recovery method thereof. The novel PCFC cathode material has the advantages of high activity, recoverability and the like, the recovery method is simple to operate and low in energy consumption, the recovery rate can reach 100% theoretically, and the novel PCFC cathode material is easy to popularize and use.

The invention relates to the technical field of preparation and application of a co-polymer biological material, and discloses a matrix-cell co-polymer biological material, which comprises a matrix-cell co-polymer, and the matrix-cell co-polymer comprises human decellularized alveolar bone matrix microparticles and human dental sac stem cells. According to the matrix-cell copolymer biological material as well as the preparation method and the application thereof, hDABMPs capable of providing a tissue-specific microenvironment and hDFSCs with development potential are utilized to prepare a developmental bionic matrix-cell copolymer biological material, and the developmental bionic matrix-cell copolymer biological regeneration material has good mechanical strength, good mechanical properties, good biocompatibility, good biocompatibility and good biocompatibility. The stem cell polymer carrying the tissue-specific microenvironment and the developmental potential provides key biological signals of a regeneration scaffold and the specific tissue microenvironment for tissue regeneration so as to support and enhance the regeneration capacity of the implanted stem cell polymer. The strategy highlights the synergistic effect of development guidance and microenvironment induction.

The invention relates to the technical field of water pollution treatment, in particular to application of a cerium salt coagulant in water treatment. The specific application method comprises the following steps: adding the cerium salt coagulant into a to-be-treated water body under stirring, carrying out a coagulation reaction, and settling floc generated by the coagulation reaction to obtain the treated water body, the cerium salt coagulant is cerium-containing nitrate, ammonium nitrate, chlorine salt, sulfate or oxalate; the water body to be treated is a water body containing organic matter-turbidity or algae. The invention solves the problem that the conventional treatment process has low removal effect on algae and organic pollutants in water and the problems of narrow applicable pH range, poor coagulation effect at low temperature and high concentration of residual metal ions in the application process of the traditional coagulant.

The invention relates to a tail gas treatment device for an industrial boiler, which is applied to the technical field of tail gas treatment devices and adopts a honeycomb ceramic-based hexagonal prism catalyst tube to improve the mass transfer efficiency; the composite anode plate integrates ICCP cathode protection and plasma electrochemical regeneration functions, inhibits catalyst corrosion and performs in-situ activation; the composite anode plate adopts a titanium-based porous framework, and a special material is arranged in the composite anode plate to generate micro-discharge plasma; the cathode collector plate adopts a stainless steel screen plate and a conductive carbon coating, so that the corrosion resistance is improved; the potential reference hole adopts a multi-stage branch structure, so that multi-point in-situ detection is realized; the regeneration liquid circulation system uses a sulfuric acid solution to dissolve and remove surface sediments; the intelligent control system integrates multiple functions, realizes full-life-cycle management of the catalyst, improves the denitration and desulfurization effects, prolongs the service life of the catalyst, and realizes intelligent and accurate control of the regeneration process.

The invention provides a tissue culture method for seedlings of apple trees, and belongs to the technical field of apple tissue culture breeding, the tissue culture method comprises the following steps: 1) disinfecting seeds of apple trees, removing seed coats, inoculating embryos after cotyledons are cut into a germination culture medium for germination, and obtaining tissue culture seedlings; and (2) cutting adventitious buds from the tissue culture seedlings, inoculating the adventitious buds into a proliferation culture medium, and carrying out proliferation culture to obtain seedlings. According to the tissue culture method, the embryos are used as explants, the embryos have better differentiation and propagation capacity, the regeneration capacity of the obtained tissue culture seedlings is higher than that of the tissue culture seedlings obtained by using other materials as explants, and the propagation coefficient is high.

The invention discloses an attapulgite-fly ash composite adsorbent as well as a preparation method and application thereof, and the preparation method comprises the following steps: crushing, grinding and screening natural attapulgite, mixing with dilute sulphuric acid, carrying out constant-temperature oscillation treatment, washing to remove residual dilute sulphuric acid after reaction, filtering and drying to obtain acidified attapulgite; the preparation method comprises the following steps: adding acidified attapulgite into deionized water, heating and stirring, adding lanthanum chloride heptahydrate and polyaluminum chloride powder, and dropwise adding ammonia water at the same time to realize loading of lanthanum and aluminum on the surface of the acidified attapulgite; after heating and stirring, filtering and drying to obtain modified attapulgite; and mixing the modified attapulgite with fly ash, then carrying out mechanical grinding treatment, putting the ground sample into a tubular furnace, and carrying out anaerobic roasting to obtain the attapulgite-fly ash defluorination adsorbent. The attapulgite-fly ash defluorination adsorbent prepared by the invention has relatively strong selectivity and specific adsorption effect on fluorine ions in wastewater discharged by a chemical plant, and has renewability.

The invention provides a trapping agent for C4 mixed hydrocarbon gas separation, a preparation method of the trapping agent and a C4 mixed hydrocarbon gas separation method. The trapping agent comprises a solid adsorbent and an organic solvent, the solid adsorbent is CALF-20 (Callidol Alkaline The total mass of the trapping agent is 100%, the content of the solid adsorbent is 15wt%-50wt%, and the content of the organic solvent is 50wt%-85wt%; the organic solvent is prepared from one or a combination of more than two of 1, 3-dimethyl-2-imidazolinone, benzyl alcohol and dimethyl phthalate. The trapping agent is excellent in effect, has the advantages of being large in n-butene adsorption capacity, high in n-isobutene / isobutene selectivity, high in adsorption speed, good in regeneration performance and the like, and provides diversified choices for separating C4 mixed hydrocarbon gas through a slurry method in industrial practical application.

The invention discloses a preparation method and application of a mesenchymal stem cell exosome-loaded absorbable suture line, noradrenaline is utilized to activate the surface of a collagen suture line, then human umbilical cord mesenchymal stem cell exosomes are assembled to the surface of the activated suture line through a soaking method, and the absorbable suture line with the surface functionalization is constructed. After the suture line is used, the wound healing effect is good, the blood vessel and cell recovery degree is good, proliferation and migration of fibroblasts can be remarkably promoted, proliferation of T lymphocytes and Th1 cells is effectively inhibited, and a powerful guarantee is provided for tissue repair.

The invention relates to responsive hydrogel loaded with bionic nano-vesicles as well as a preparation method and application of the responsive hydrogel, and belongs to the technical field of medical hydrogel. The method comprises the steps that odontogenic mesenchymal stem cells are stimulated by a chemical vesicle stimulant and then mixed with melatonin mother liquor for extrusion, the bionic nano vesicles are obtained, the chemical vesicle stimulant contains a buffer solution, a dithiothreitol solution and a paraformaldehyde solution, and the buffer solution contains 8.5-9 g / L of sodium chloride, 0.2-0.24 g / L of calcium dichloride and 2.3-2.4 g / L of 4-hydroxyethyl piperazine ethanesulfonic acid; 6-arm-PEG-pp-NH2 coupled with polypeptide capable of being cut by matrix metalloproteinase, six-arm polyethylene glycol succinimide glutarate and the bionic nano-vesicle are prepared into a first precursor solution and a second precursor solution respectively, the first precursor solution and the second precursor solution are mixed and subjected to standing to form gel, and the responsive hydrogel is prepared. According to the invention, the responsive hydrogel capable of obviously enhancing bone regeneration capacity is obtained.

The invention discloses an environment-friendly waste asphalt mixture biological regenerant. The environment-friendly waste asphalt mixture biological regenerant comprises 60-70 wt% of an oil component, 10-20 wt% of a regeneration component, 4-8 wt% of an activator, 2-8 wt% of a penetrant and 2-5 wt% of a solubilizer, the oil component is composed of waste pine needle oil and waste epoxidized soybean oil. The environment-friendly waste asphalt mixture biological regenerant provided by the invention can improve the colloid structure of regenerated asphalt, enables the regenerated asphalt to recover good performance, has excellent permeability, can greatly improve the low-temperature performance of the waste asphalt mixture (PAP), and ensures good pavement performance of the waste asphalt mixture (PAP).

The invention relates to a composition for promoting cell regeneration and application thereof, and particularly provides a composition for promoting cell regeneration, the composition comprises L-tryptophan oxalate, isosorbide-2-acetate and glabridin, and the composition is applied to preparation of a cell regeneration agent and construction of a cell model. The participation of the composition can effectively improve the proliferation capacity of cells and the expression level of CD63 in the cells. The method not only effectively improves the regeneration capacity of cells, but also is simple to operate and low in cost, and can be applied to the fields of preparation of cosmetics, skin care products, wound repair materials or medicines and skin repair.

This invention provides novel stem cell activators, topical skin agents containing the aforementioned stem cell activators, and skin cosmetics containing the aforementioned stem cell activators. The stem cell activator of this invention comprises at least one compound selected from compounds (including optically active agents) shown in formula (1), salts of the aforementioned compounds, and hydrates thereof as active ingredients. In the following formula, R... 1 R 2 Represents a hydrogen atom or a hydrocarbon group. R 3 Represents a hydrogen atom or an organic group. n represents an integer greater than or equal to 1. The above hydrocarbon groups may have substituents. [Chemical Formula 1]

This utility model discloses a solid-liquid separation diatomaceous earth filtration system, relating to the field of filtration technology. It includes: a coating tank for storing a liquid mixed with diatomaceous earth, a coating circulation pipeline, and a raw liquid tank, a delivery pump, a filter cartridge, and a purified liquid tank connected in sequence. The filter cartridge is vertically arranged inside the cartridge. A drain port and a liquid inlet pipeline are provided at the bottom of the cartridge, and an outlet pipeline and a cleaning pipeline, both connected to the filter cartridge, are provided at the top. A drain valve is provided at the drain port. The top of the inner cavity of the cartridge is connected to a first air supply pipeline, and the bottom of the inner cavity is connected to a pressure return pipeline. The bottom of the coating tank is connected to the liquid inlet channel of the cartridge via a circulation pump. One end of the coating circulation pipeline is located inside the coating tank, and the other end is connected to the filter cartridge. In this utility model, the filter cartridge is coated with soil using the coating tank. Gas supplied through the first air supply pipeline forces the raw liquid inside the cartridge into the pressure return pipeline, saving raw liquid resources and improving the regeneration effect of the filter cartridge.

This invention relates to the field of petrochemical technology, specifically to a method and system for dehydrogenating low-carbon alkanes to olefins. The method includes: (1) introducing low-carbon alkanes into a moving bed reaction zone packed with a dehydrogenation catalyst to undergo a dehydrogenation reaction, obtaining dehydrogenation products, and separating the dehydrogenation products to obtain hydrogen, olefins, and alkanes; (2) introducing the spent catalyst flowing out from the bottom of the moving bed reaction zone into a regenerator for regeneration treatment to obtain a regenerated catalyst, and recycling the regenerated catalyst back to the moving bed reaction zone to participate in the dehydrogenation reaction. Using the method provided by this invention, the conversion rate of low-carbon alkanes can be improved, continuous catalyst circulation can be achieved, and the operating cycle of the unit can be extended.

The utility model discloses a VOCs organic waste gas treatment device which comprises a carbon box, clamping seats are fixedly connected to the two sides of the inner side face of the carbon box, activated carbon adsorption plates are clamped in the clamping seats, and a conveying pipe is fixedly connected to the bottom of the inner side face of the carbon box. According to the VOCs organic waste gas treatment device, an activated carbon adsorption plate, a fresh air heat exchanger, a fan and a combustion furnace are arranged, the activated carbon adsorption plate adsorbs organic components in waste gas into micropores of activated carbon for concentration, filtered clean gas reaches the standard and is discharged, and fresh air is heated to a preset value through the fresh air heat exchanger and then enters a carbon box through a second air inlet pipe; organic waste gas subjected to desorption treatment is purged, meanwhile, VOCs organic waste gas is conveyed into a combustion furnace through a gas collecting pipe and a gas collecting hood through a draught fan, the VOCs organic waste gas is decomposed into carbon dioxide and water vapor after being subjected to catalytic combustion, and finally the VOCs organic waste gas is conveyed to a fresh air heat exchanger through a connecting pipe to be discharged after being subjected to heat exchange and cooling and reaching the standard, so that an activated carbon adsorption plate can be recycled; and the use cost is reduced.

The invention relates to a belt type vacuum filter capable of automatically adjusting blanking speed, which comprises a main body, a rubber belt sleeved on the main body and filter cloth sleeved on the outer side of the rubber belt, a feeding assembly used for paving slurry on the filter cloth is arranged on the main body, and the feeding assembly comprises a feeding pipeline and a blanking hopper arranged below the feeding pipeline. A baffle is arranged on the feeding pipeline in a sliding mode, a tensioning roller is arranged below the rubber belt in a sliding mode, the tensioning roller descends in the process that the slurry is poured into the feeding assembly and drives the baffle to slide to block the feeding pipeline, and a filtering assembly for filtering the slurry is arranged on the side face of the feeding assembly. The side surface of the main body is provided with a scraper for discharging the slurry on the filter cloth, and a cleaning assembly for cleaning the filter cloth is arranged below the scraper, so that the problems that the discharging speed is fixed, and the slurry density or thickness is too high, so that thorough filtration cannot be ensured during filtration, and the quality of finished products is influenced due to non-uniform filtration are solved.

The application discloses a sugarcane regeneration-promoting small peptide ScREF1 and application thereof, and belongs to the technical field of plant biotechnology and sugarcane tissue culture. The amino acid sequence of the ScREF1 is shown as SEQ ID NO. 1. The application provides a high-activity sugarcane-specific regeneration-promoting small peptide ScREF1, and provides a matching small peptide mother liquor preparation and callus induction / differentiation medium adding process, and the optimal application concentration is determined in stages. The ScREF1 provided by the application can overcome the defects of existing sugarcane tissue culture, such as serious callus browning, weak embryogenic callus proliferation, low regeneration efficiency and strong genotype dependence. The application can be widely applied to factory-like rapid propagation of sugarcane elite varieties, cultivation of virus-free seedlings, genetic transformation of transgenic materials, creation of CRISPR gene editing materials, and significantly improves the efficiency of sugarcane molecular breeding.

The invention provides a desulfurization ash regeneration device and method, and relates to the technical field of desulfurization ash regeneration. The device comprises a shell, the shell is provided with a reaction cavity, a feeding port and a discharging port, and a turnover sand core is arranged between the reaction cavity and the discharging port and used for controlling the desulfurization ash discharging process; a gas inlet is formed between the discharge hole and the sand core and is used for introducing reaction gas which reacts with the desulfurized fly ash into the reaction cavity; an ignition device; the circular reaction unit is used for realizing circular reaction of the desulfurized fly ash in the reaction cavity to reach set conditions; and an air outlet. When the device is used for regenerating the desulfurized fly ash, reaction gas can be used as a heat source and a reducing atmosphere at the same time, the desulfurized fly ash is efficiently and quickly regenerated and decomposed into calcium oxide in the reaction cavity, and the energy consumption is reduced; the regenerated desulfurized fly ash can be used in a sintering or pellet production process, so that the treatment cost of waste ash and the use amount of new lime are reduced, and the environmental protection cost and carbon emission of enterprises are effectively reduced.

The utility model discloses an ion exchange resin device convenient to regenerate, which comprises a resin tank, a lower filter plate is hermetically arranged at the lower part of the resin tank, and a water collecting filter plate is hermetically arranged at the upper part of the resin tank; an overflow port and a pressure relief port are respectively formed in the top of the resin tank, and a water outlet and an air inlet are respectively formed in the bottom of the resin tank; a water inlet is formed in the upper part of the resin tank between the water collecting filter plate and the lower filter plate; and a regenerant inlet is formed in the side wall of the resin tank below the lower filter plate. The device has the advantages that the regenerant can be in full contact with resin all the time, so that the resin is fully regenerated, the utilization rate of the regenerant is increased, the consumption of the regenerant is reduced, the discharge amount and the discharge concentration of regenerated waste liquid are reduced, and the economic benefit is remarkable. The backwashing fan blows air into the resin tank to disturb the resin, so that the regeneration effect is improved, the resin can be loosened, the adsorption effect in the adsorption process is improved, and the effluent quality is improved.

The invention discloses a full-automatic resin regeneration device and a use method, and belongs to the field of resin regeneration, the full-automatic resin regeneration device comprises a second regeneration liquid storage tank, the second regeneration liquid storage tank is connected with an instrument resin exchange column group through a regeneration control group, and a plurality of resin exchange columns are provided with color sensors; the instrument resin exchange column group is connected with a flushing liquid supply system through a conventional flushing electric valve group and a backwashing electric valve group; a cleaning device and a regeneration device are combined into a whole, the occupied area of equipment is reduced, the cleaning and regeneration functions are achieved at the same time, and inconvenience and space waste caused by separation of a traditional device are avoided; the full-automatic regeneration process is adopted, switches of all valves and pumps are accurately controlled, quantitative control over the regeneration process is achieved, dependence on experience of operators is reduced, stability and consistency of the regeneration effect are improved, and the problems that quantitative control cannot be achieved through manual operation, labor intensity is large, resin is prone to being damaged, impurities are introduced and the like are solved.

This document relates to methods and materials for genome engineering in eukaryotic cells, and in particular to methods for increasing the efficiency of genome engineering (i.e., transformation or genome editing) by co-delivering a combination of one or more enhancer polypeptides and enhancer genes with genome engineering components.

The application relates to the technical field of vehicle exhaust treatment, and provides an exhaust treatment system and a vehicle. The exhaust treatment system comprises a particle trap and a regeneration device, the regeneration device comprises an oil-gas mixing part, a gas path assembly and an oil path assembly, and a fluid driving part connected between the oil-gas mixing part and the particle trap, and the fluid driving part can drive an oil-gas mixture in the oil-gas mixing part to flow into the particle trap. The exhaust treatment system provided by the application sets one fluid driving part, which can facilitate the smooth flow of exhaust gas and fuel into the oil-gas mixing part, the exhaust treatment system has a simple structure, and the oil-gas mixture can smoothly flow to the downstream, which is helpful for the combustion regeneration of the particle trap, has a good exhaust treatment effect, and can reduce the emission of pollutants.

The invention relates to the technical field of waste gas treatment equipment, and discloses waste gas purification equipment for a PE pipe production line, the waste gas purification equipment comprises a zeolite rotating wheel, the zeolite rotating wheel comprises a front cylinder and a rear cylinder, the front cylinder and the rear cylinder are internally and movably connected with a front rotating wheel and a rear rotating wheel which keep rotating respectively, and a separation cavity is formed between the rear rotating wheel and the front rotating wheel; a front adsorption cavity, a front desorption cavity and a front cooling cavity are arranged between the front barrel and the separation cavity, a rear adsorption cavity, a rear desorption cavity and a rear cooling cavity are arranged between the separation cavity and the rear barrel, the front adsorption cavity and the rear adsorption cavity are connected in series, and the end part of the front adsorption cavity is communicated with waste gas through an adsorption pipe. According to the waste gas purification equipment for the PE pipe production line, a tandem type double-rotating-wheel structure is adopted, high-boiling-point pollutants are preferentially adsorbed and borne through the front rotating wheel, and adjustable internal reflux and differential rotating speed design are matched, so that the problem of zeolite pore channel blockage is solved, meanwhile, the concentration multiple of low-concentration waste gas is greatly increased, and the service life of the waste gas is prolonged. And stable self-heating operation of the catalytic oxidation furnace is ensured.

The invention relates to the field of bone tissue engineering and the field of biomedical materials, in particular to application of an ultrasonic response piezoelectric collagen scaffold. According to the invention, full-thickness pigskin is used as a raw material, hair and subcutaneous adipose tissue are removed, and then decellularization is carried out so as to obtain the membrane-like scaffold. The membrane-like scaffold retains a complete three-stage structure of natural collagen, which is a source of the natural collagen having a piezoelectric effect; meanwhile, a piezoelectric signal detection result shows that periodic piezoelectric signals appear on the membrane-shaped stent, and then the collagen stent provided by the invention is proved to have an intrinsic piezoelectric effect. Experimental results show that mesenchymal stem cells can be attached to the surface of the collagen scaffold and can promote repair and regeneration of bone tissues, and in addition, rat subcutaneous ectopic bone regeneration experiments prove that the collagen scaffold provided by the invention has a good bone regeneration promoting effect under ultrasonic stimulation.

The invention belongs to the technical field of advanced materials, and relates to a hydrogel material for promoting DHA intracellular lipid reduction and a preparation method and application thereof. Hydrogel formed by polyethylene glycol diacrylate (PEG-DA) and dithiothreitol (DTT) is used as a support to load nanometer microspheres, the nanometer microspheres load docosahexaenoic acid (DHA), and the nanometer microspheres are composed of chitosan and fucoidin according to the mass ratio of 5: (1-10). The hydrogel provided by the invention can reduce the lipid droplet accumulation level in local tissue cells of a hyperlipidemia patient and promote in-situ bone regeneration.

The invention discloses an application of a GmWUS2 protein in regulation and control of soybean regeneration. The invention belongs to the technical field of biology, and particularly relates to application of GmWUS2 protein in regulation and control of soybean regeneration. The invention provides application of protein or an expression substance for regulating and controlling a gene or a substance for regulating and controlling the activity or content of the protein in regulating and controlling the regeneration capacity of plants, the amino acid sequence of the protein GmWUS2 is a sequence 3, the regeneration capacity of the protein can be regulated and controlled by regulating and controlling the expression of the protein GmWUS2, and material accumulation is provided for soybean breeding; and a new strategy and a new direction are provided for high yield of soybeans.

The invention relates to a nano odontogenic mesenchymal stem cell vesicle as well as a preparation method and application thereof, and belongs to the technical field of regenerative medicine and drug carriers. The method comprises the following steps: obtaining odontogenic mesenchymal stem cells; adding a chemical vesicle stimulant and then putting the mixture into a CO2 constant-temperature incubator for stimulation to obtain a giant plasma membrane vesicle solution of the odontogenic mesenchymal stem cells; repeatedly extruding through a polycarbonate film by using a lipidosome extruder to obtain the nano odontogenic mesenchymal stem cell vesicles of which the particle sizes are less than or equal to 200nm; the chemical vesicle stimulant comprises a buffer solution, a dithiothreitol aqueous solution and a paraformaldehyde solution, wherein the buffer solution comprises 8.5-9 g / L of sodium chloride, 0.2-0.24 g / L of calcium dichloride, 2.3-2.4 g / L of 4-hydroxyethyl piperazine ethanesulfonic acid and water. The obtained vesicles are high in yield and purity, have efficient bone tissue targeting property, and can prolong the in-vivo circulation time of the medicine and enhance the bone regeneration capacity.