The invention relates to an antibiotic-free premix feed for growing-finishing pigs. The antibiotic-free premix feed is mainly prepared from cupric sulfate pentahydrate, ferrous sulfate, zinc glycinate, selenium yeast, ferrous glycinate, manganese sulfate, cobalt sulfate, sodium selenite, steamed bone meal, magnesium carbonate, vitamins, vitamin powder, dicalcium phosphate, table salt, phytase, compound enzymes, lysine, methionine, betaine and choline chloride. Yucca, unprocessed rehmannia roots, buffalo horns, rhizoma coptidis, fructus gardeniae, cortex moutan, radix scutellariae, radix paeoniae rubra, figwort roots, rhizoma anemarrhenae, fructus forsythiae, platycodon roots, licorice roots, lophatherum herbs, lumbricus, herba asari and radix isatidis are added to the premix feed disclosed by the invention to be used as pig feed additives for replacing Western medicines and antibiotic drugs, so that the quality and the mouth feel of pork can be greatly improved, the growing properties of the growing-finishing pigs are improved, the immune function of the growing-finishing pigs can also be improved, antibiotics are prevented from being used, and further antibiotics are prevented from being enriched in human bodies after people eat the pork. The antibiotic-free premix feed is free from medicine residue pollution and free from heavy metal residues, so that the safety of meat foods eaten by people is guaranteed.