4results about How to "High biological potency" patented technology

The invention belongs to the technical field of preparation of sea cucumber peptides, relates to preparation of sea cucumber small molecule peptides, and relates to a preparation method of sea cucumber peptides with composite effects of protecting liver and preventing liver cirrhosis, and the sea cucumber peptides with various effects are prepared by using fresh and alive sea cucumbers as raw materials through protease hydrolysis, fishy smell removal, deodorization and other processes. The sea cucumber peptide has the advantages of good solubility, good stability, low viscosity and the like. Compared with the transportation function of amino acid, the sea cucumber active oligopeptide has the characteristics of quick absorption, low consumption and difficulty in saturation, can be added into food, health food, medicine and the like, and has the effects of supplementing nutrition, protecting the liver function, preventing liver cirrhosis, supplementing mineral substances, protein and vitamins and the like.

The application discloses a method for efficiently extracting heparin sodium from biological materials, and the method comprises the following steps: cleaning and crushing the raw material at low temperature; adding poloxamer, ammonium sulfate and complex enzymes to perform synergistic enzymolysis under mild and neutral conditions; after the reaction is completed, the temperature is increased to above the cloud point of the polymer, liquid-liquid two-phase separation is triggered, fat-soluble impurities are synchronously removed, and the water phase rich in heparin sodium is collected; after the water phase is purified through ion exchange, concentration, alcohol precipitation and vacuum drying are sequentially performed, then vibration screening and low-temperature drying are performed, and finally, high-purity heparin sodium powder is obtained. Through the intelligent phase change characteristics of the temperature-sensitive polymer, the high-efficiency enzymolysis and primary purification are coupled, the yield and purity of heparin are significantly improved, the high-salt, strong-alkali or high-temperature conditions in the traditional process are avoided, the biological activity of the product is effectively protected, and the yield is improved.

This invention belongs to the field of biomedical materials, and particularly relates to a hydrogel for cartilage repair and its preparation method. The preparation method of the hydrogel includes the following steps: (1) adding cross-linked modified chitosan and 8-O-acetylganoside methyl ester to a collagen solution, adjusting the pH to obtain a collagen polysaccharide solution; (2) adding metal ion microspheres to the collagen polysaccharide solution of step (1), stirring and reacting, then adding microbial transglutaminase for heating and reacting, adjusting the pH to obtain a mixed solution; (3) adding 1,4-butanediol diglycidyl ether and growth factors to the mixed solution of step (2), adjusting the pH, water bath, and dialysis to obtain the hydrogel. This preparation method is simple, and the obtained hydrogel has excellent mechanical strength and adhesion properties.

The invention relates to the technical field of feed additives, in particular to a functional nutrition bag for preventing and treating foot pad inflammation of meat ducks as well as a preparation method and application thereof, and the functional nutrition bag comprises the following components in parts by weight: 100-200 parts of macleaya cordata extract, 10-30 parts of exogenous enzyme preparation, 3-7 parts of candida krusei, 30-60 parts of zinc, 5-20 parts of astragalus polysaccharide and 100-200 parts of silicon dioxide. According to the invention, a plurality of functional substances are applied to meat ducks which grow quickly according to the pathogenic factors of the foot pad inflammation of the meat ducks. The feed can improve the body health of meat ducks, repair skin barriers, improve the immune function of the whole body and reduce inflammatory quality.