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Application of zinc glutamate and derivatives thereof as animal feed additive for promoting growth

A feed additive, zinc glutamate technology, applied in animal feed, animal feed, application, etc., can solve the problems of low water solubility, poor solubility and acid resistance, and achieve low water solubility, high bioavailability, and pollution reduction. Effect

Active Publication Date: 2010-07-28
GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although zinc glycinate and zinc methionine commonly used clinically now have higher bioavailability than inorganic zinc, they have high solubility in water and poor acid resistance (see the test results in the content of the present invention), so ideal amino acid chelated zinc Not only can it ensure its high bioavailability in the body, but it also needs to have low water solubility and strong acid resistance to ensure that trace elements can reach the intestinal tract in an organic form and be absorbed and utilized

Method used

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  • Application of zinc glutamate and derivatives thereof as animal feed additive for promoting growth
  • Application of zinc glutamate and derivatives thereof as animal feed additive for promoting growth
  • Application of zinc glutamate and derivatives thereof as animal feed additive for promoting growth

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] (1) Synthesis of zinc glutamate:

[0023] A. Preparation of 10% sodium glutamate solution: Weigh 100 grams of sodium glutamate (chemically pure) and dissolve it in 1000 ml of water;

[0024] B. Preparation of 14.38% zinc sulfate solution: the exact amount of 143.8 grams of zinc sulfate heptahydrate (chemically pure) is dissolved in 1000ml of water;

[0025] C. Mix 1000ml each of 10% sodium glutamate solution and 14.38% zinc sulfate solution, then adjust the pH value of the aforementioned mixed solution to 7.0 with NaOH solution, stir and react at room temperature for 2 hours, centrifuge, take the precipitate, and wash with water suspension centrifugation Precipitation was carried out for 3 times, followed by drying at 100° C. to constant weight to obtain 116.64 g of zinc glutamate with a yield of 96.09%.

[0026] (2) measure respectively the content of glutamic acid and zinc ion of the zinc glutamate obtained in step (1):

[0027] A. Determination of zinc ion content:...

Embodiment 2

[0118] Growth-promoting effect of different derivatives of zinc glutamate on animals

[0119] (1) Preparation of Different Zinc Glutamate Derivatives

[0120] A. Zinc glutamate hydrochloride: Weigh 100 grams of ZnCl 2 and 137.3 grams of sodium glutamate were dissolved in 1000ml of water, respectively, stirred until completely dissolved, mixed the two, adjusted the pH value of the mixed solution to 4.0 with 0.1M hydrochloric acid solution, heated and continuously stirred for the reaction, and harvested the crystals. Dry to constant weight. Dissolve the product with 1 gram of water and dilute to 100 ml, and measure the content of zinc ion (atomic absorption method), chloride ion (Moire method) and glutamic acid (amino acid analyzer) in the solution. Results The zinc ion concentration was 2.692 mg / ml, the chloride ion content was 1.470 mg / ml, and the glutamic acid content was 6.005 mg / ml. From this, it can be inferred that the obtained crystal was zinc glutamate and hydrochlori...

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Abstract

The invention discloses an application of zinc glutamate and derivatives thereof as animal feed additive for promoting growth. In the invention, the zinc glutamate is found to have low water-solubility, high acid resisting ability and high bioavailability; used as the feed additive for promoting growth, the zinc glutamate has higher safety and higher antibiotic activity compared with other zinc sources such as oxide zinc, basic zinc chloride and zinc glycinate, and the addition of zinc ions can be reduced by 80-90 percent. The invention can reduce the production cost as well as the environmental pollution, and simultaneously reduce the toxic and side effects of high zinc content on animals.

Description

technical field [0001] The invention particularly relates to the application of zinc glutamate or a derivative thereof as an animal growth-promoting feed additive, which belongs to the field of feed. Background technique [0002] As one of the essential trace elements in animal body, zinc participates in various metabolic reactions in the body and plays an important role in the growth and development of animals. The total content of zinc in normal animals is about 30 ppm. The National Research Council (NRC) recommends that the zinc requirement of piglet feed is 100 ppm, and pigs have a strong tolerance to zinc, which can reach 20 to 30 times the normal requirement. It has been reported that adding 3000ppm of zinc oxide to the diet can significantly increase the body weight, average daily gain and daily feed intake of weaning-stressed piglets, reduce feed-to-weight ratio and post-weaning diarrhea rate, and effectively prevent weaning stress syndrome in piglets. Studies have ...

Claims

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Application Information

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IPC IPC(8): A23K1/16
Inventor 彭险峰覃宗华
Owner GUANGZHOU INSIGHER BIOTECHNOLOGY CO LTD
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