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57results about How to "High load rate" patented technology

Robot intelligent scheduling and management and control system and method for hospital delivery business

The invention discloses a robot intelligent scheduling and management and control system and method for hospital delivery services, and relates to the technical field of realizing material delivery services by using robots. The scheduling platform determines the execution category according to the attribute of the transport work order, and when the execution category is robot execution, the scheduling platform assigns the transport work order to the robot according to an order insertion, sequential and / or proximity strategy; a shortest-time-consumption planning strategy is adopted, and the path of the robot assigned to convey the work order is planned; and when executing the work order, the robot interacts with the scheduling platform in real time and reports the task completion condition. The scheduling strategy of the transport work order is further optimized, the transport efficiency and the load rate of the transport robot are improved, and the scheduling platform can master the information of each node in the transport path in real time, so that reference is provided for subsequent planning of the transport path, and the transport efficiency of the transport robot is further improved.
Owner:NANJING TIANSU AUTOMATION CONTROL SYST CO LTD

High-temperature-resistant metallurgical vehicle-mounted flexible cable and preparation method thereof

The invention belongs to the technical field of cables, and particularly relates to a high-temperature-resistant metallurgical vehicle-mounted flexible cable and a preparation method thereof. According to the high-temperature-resistant cable material, polyimide, polyphenylene sulfide and polybenzimidazole are matched, so that the high-temperature-resistant cable material is endowed with extremely high high temperature resistance, can resist the high temperature of 300 DEG C, and is extremely suitable for cable materials for metallurgy. Then, the flexibility of the material is improved by adding a flexible polyether-ether-ketone / nano silicon dioxide compound, and the surface of nano silicon dioxide is treated, so that the loading rate of polyether-ether-ketone can be increased, the phase separation phenomenon of polyether-ether-ketone in a blend is prevented, and uniform dispersion is promoted. And finally, the prepared high-temperature-resistant metallurgical vehicle-mounted flexible cable material is used as a filler and a sheath of the cable material, so that the cable structure is reduced, the production difficulty of the cable is reduced, the production process is simplified, and the material and process requirements are reduced, thereby achieving the purposes of reducing the cost and improving the production efficiency to a certain extent.
Owner:GUANG DONG LI GUANG DIAN QI SHI YE YOU XIAN GONG SI

Instant recombinant collagen nanofiber mask as well as preparation method and application thereof

The invention discloses an instant recombinant collagen nanofiber mask as well as a preparation method and application thereof. The nanofiber facial mask in the facial mask is a layered substance formed by continuously stacking fibers by taking small-molecular-weight recombinant collagen, high-molecular-weight recombinant collagen and water-soluble polymers as matrixes and utilizing an electrostatic spinning technology, and has the advantages of large specific surface area, high porosity, high active substance loading rate and the like; the active ingredients are attached or embedded into the nanofibers in the form of small particles, so that the absorption efficiency is higher, and the active ingredients can easily permeate into the deep layer of the skin, so that the functions of moisturizing, resisting oxidation, resisting inflammation, resisting aging, whitening, relieving and the like are achieved.
Owner:SOUTH CHINA UNIV OF TECH

Zeolite rotating wheel for treating styrene-containing organic waste gas

The invention belongs to the technical field of environmental protection equipment, and particularly discloses a zeolite rotating wheel for treating styrene-containing organic waste gas. The zeolite rotating wheel comprises an anti-polymerization wheel core, a VOCs wheel core and a connecting shaft; the anti-inhibition wheel core is provided with a porous channel structure penetrating front and back, and an anti-inhibition molecular sieve is loaded on the inner wall of the channel; the VOCs wheel core is attached to the rear portion of the anti-polymerization wheel core and is provided with a porous channel structure penetrating front and back, a zeolite molecular sieve is loaded on the inner wall of the channel, and the connecting shaft penetrates through the anti-polymerization wheel core and the VOCs wheel core to connect the anti-polymerization wheel core and the VOCs wheel core in series and fixedly connect the anti-polymerization wheel core and the VOCs wheel core. According to the present invention, the efficient adsorption and concentration of the easily-polymerized styrene component and the conventional non-methane total hydrocarbon can be achieved, the requirements of the chemical industry, the plastic industry, the printing industry, the coating industry and other industries on the styrene-containing and non-methane total hydrocarbon-containing waste gas working condition treatment are met, the purification effect of the styrene-containing organic waste gas is substantially improved, and the service life of the equipment is substantially prolonged.
Owner:SHANGHAI LANBAO ENVIRONMENTAL PROTECTION TECH CO LTD

Bi-selenium bond-containing poly-beta amino ester carrier for mRNA delivery and preparation method and application thereof

The invention discloses a diselenide-bond-containing poly-beta amino ester carrier for mRNA delivery and a preparation method and application thereof, and the preparation method of the diselenide-bond-containing poly-beta amino ester carrier comprises the following steps: taking a synthesized diselene-1, 6-hexanediol diacrylate monomer (DSEDA) and hydrophobic amine as raw materials to react to obtain a product as a polymer intermediate; the raw material of the hydrophobic amine is one of C8, C12 and C16; the # imgabs0 # hydrophilic amine raw material is one of 2A1, 2A4 and 2A5; a diselenide bond is introduced into a main chain of the structure of the synthesized linear cationic polymer product, tertiary amine N capable of being protonated into cations exists in the main chain structure, and the tertiary amine N can be effectively combined with nucleic acid with negative charges through electrostatic interaction, so that the nucleic acid loading rate is increased; according to the invention, hydrophobic alkane chains with proper number and length are provided, a hydrophobic cavity can be formed when the nanoparticles are formed, the stability of the nanoparticles is improved, and the nanoparticles have good application in delivery of mRNA (messenger Ribonucleic Acid) molecules.
Owner:ZHEJIANG UNIV OF TECH

Nanometer pesticide with photolysis resistance based on enzymatic hydrolysis lignin and preparation method

The invention relates to a nano-pesticide with photolysis resistance based on enzymatic hydrolysis lignin and a preparation method, and belongs to the technical field of nano-pesticides. The nano-pesticide is a black sphere, the effective particle size is 160-200 nm, the drug loading rate is 35.72%, the nano-pesticide has good photolysis resistance, and the photolysis half-life period is prolonged by 1.56 times compared with that of prothioconazole original drug; the composition is used for rice blast diseases. According to the nano pesticide, enzymatic hydrolysis lignin is used as a carrier, a prothioconazole bactericide is used as a loading drug, and tannic acid and copper ion coatings are used for coating; functional groups such as phenol and ketone in the enzymatic hydrolysis lignin can effectively absorb a large range of ultraviolet rays and reduce ultraviolet radiation, so that the enzymatic hydrolysis lignin has excellent oxidation resistance and ultraviolet resistance; meanwhile, the enzymatic hydrolysis lignin has renewability, environmental protection property and degradability, and the coating of tannic acid and copper ions can further improve the antifungal ability of the nano pesticide, improve the thermal stability of the nano pesticide, increase the release rate of the pesticide and have the ability to reduce the loss of the pesticide.
Owner:ANHUI AGRICULTURAL UNIVERSITY

Auricularia auricula polysaccharide / casein emulsion gel as well as preparation method and application thereof

The invention discloses black fungus polysaccharide / casein emulsion gel as well as a preparation method and application thereof. The preparation method comprises the following steps: 1) mixing an aqueous solution of auricularia auricula polysaccharide with an aqueous solution of casein to obtain a protein-polysaccharide compound solution; (2) a water phase is added into the oil phase and mixed, the water phase is the protein-polysaccharide compound solution, the obtained mixture is subjected to ultrasonic homogenization, and emulsion is obtained; and 3) adding gluconic acid-delta-lactone into the emulsion, mixing, and incubating to obtain the auricularia auricula polysaccharide / casein emulsion gel. The auricularia auricula polysaccharide / casein emulsion gel disclosed by the invention is applied to curcumin encapsulation. After the black fungus polysaccharide is added, the gel performance of the casein emulsion gel is obviously improved; after the auricularia auricula polysaccharide is added, the loading rate of the casein emulsion gel loaded with curcumin is obviously increased.
Owner:SHANXI AGRI UNIV

Radioactive medical isotope Ra-223 stably-labeled rare earth nano diagnosis and treatment preparation as well as preparation method and application thereof

The invention discloses a radioactive medical isotope Ra-223 stably-labeled rare earth nano diagnosis and treatment preparation as well as a preparation method and application thereof. According to the invention, by constructing a dual protection mechanism of the shell layer and the functional biomolecular layer, the Ra-223 is effectively packaged, the recoil nuclei of the Ra-223 are reserved at the tumor part and are prevented from escaping to the surrounding environment of the tumor, the safety of the Ra-223 treatment process can be enhanced, the radioactive energy is ensured to accurately act on the focus, and the treatment effect of the Ra-223 is improved. Meanwhile, the damage risk to healthy tissues is minimized.
Owner:ZHONGKE RARE EARTH NANOTECHNOLOGY (HEBEI) CO LTD

Preparation device of naringin complex loaded by octenyl succinic acid modified porous starch ester

The present application relates to the technical fields of medical health food, and discloses a preparation device for naringin compound loaded by octenyl succinic acid modified porous starch ester, which comprises a preparation liquid ultrasonic mixing cylinder assembly, a mixing top cover assembly is arranged on the top of the preparation liquid ultrasonic mixing cylinder assembly, and a mixed liquid shaking and stirring assembly is arranged on the mixing top cover assembly; a rocker arm base assembly is rotatably arranged at the bottom of the preparation liquid ultrasonic mixing cylinder assembly; a preparation liquid mixing cylinder assembly is fixedly arranged on both sides of the top of the preparation liquid ultrasonic mixing cylinder assembly; the preparation liquid ultrasonic mixing cylinder assembly comprises a preparation liquid ultrasonic mixing cylinder, a plurality of mixing cylinder bottom arm tables are fixedly arranged on the preparation liquid ultrasonic mixing cylinder through reinforcing rib plates, and a bottom arm table main shaft rod is fixedly arranged on the mixing cylinder bottom arm table; an aeration pipe is fixedly arranged at the bottom of the preparation liquid ultrasonic mixing cylinder, and a liquid pump is fixedly arranged outside the bottom of the preparation liquid ultrasonic mixing cylinder. The present application has the characteristics of sufficient mixing.
Owner:ZHEJIANG ACADEMY OF AGRICULTURE SCIENCES

Method for preparing nano-composite containing pan jade extract and application of nano-composite

The invention relates to the technical field of mineral extraction and compound preparation thereof, in particular to a preparation method and application of a nano compound containing a pan jade extract. The method comprises the following steps: S1, crushing and sieving pan jade to obtain pan jade powder, then adding a first solvent, carrying out ultrasonic treatment, centrifuging, taking supernatant liquid, filtering, and carrying out spin-drying, redissolving and vacuum drying on filtrate to obtain pan jade extract; s2, preparing a ZIF-8 nano material from zinc nitrate hexahydrate and 2-methylimidazole; s3, loading the pan jade extract onto the ZIF-8 nano material, so as to obtain ZIF-8 loaded with the pan jade extract; and S4, carrying out functional modification on the ZIF-8 loaded with the pan jade extract by utilizing folic acid to obtain the nano-composite containing the pan jade extract. The nano-composite containing the pan jade extract prepared by the invention is used for resisting tumor proliferation.
Owner:JILIN PANLONG JADE DEV CO LTD

A method for preparing starch-polyphenol nanostructure network

ActiveCN118994423BHigh load rateevenly distributedNanonetworkPolyphenol
The present invention discloses a method for preparing a starch-polyphenol nanostructure network, the method comprising the following steps: (1) preparing a starch suspension; (2) thermal gelatinization; (3) microfluidization treatment; (4) heat treatment; (5) vacuum freeze drying; (6) ball milling treatment; (7) high temperature reaction; (8) alcohol precipitation treatment; (9) centrifugation treatment; (10) vacuum freeze drying. The present invention utilizes physical field microfluidization to induce the formation of starch short chains with free radicals, drives the short chains to crosslink and entangle into a starch nanonetwork through heat treatment, and induces the generation of free radicals on the surface of the network structure again through ball milling, thereby promoting the covalent bonding of starch chains and polyphenols, and preparing a starch-polyphenol nanostructure network with a high loading rate.
Owner:ZHEJIANG UNIV

Sodium alginate microspheres as well as preparation method and application thereof

The invention relates to the technical field of drug carriers, and discloses a sodium alginate microsphere and a preparation method and application thereof.The preparation method comprises the steps that a suspension containing cellulose and sodium alginate is added into an oil phase to be emulsified, a water-in-oil emulsion is formed, then a cross-linking agent is stirred and mixed to be subjected to a cross-linking reaction with the water-in-oil emulsion, original microspheres are obtained, and the sodium alginate microsphere is prepared. Finally, the original microspheres are treated with etching liquid, and the sodium alginate microspheres are obtained. According to the water-in-oil emulsion, cellulose cannot be dissolved in water and oil, so that cellulose in the water-in-oil emulsion is dispersed in liquid drops in a suspended state; in the cross-linking reaction process, cellulose does not participate in cross-linking and is embedded into the interior and the outer surface of a sodium alginate skeleton formed by the cross-linking reaction; after the original microspheres are treated with an etching solution, cellulose is degraded to different degrees, so that pore channels are reserved in the microspheres, the finally prepared sodium alginate microspheres are rich in pore channels, large in specific surface area and small in density, and the drug loading rate of the sodium alginate microspheres is increased.
Owner:GUANGZHOU KONCEN BIOSCI

Chelating agent modified biochar / MOF materials and electrochemical sensors

The present invention belongs to the field of electrochemical sensors, and relates to chelating agent-modified biochar / MOF materials and electrochemical sensors. The present invention first utilizes the adsorption properties of biochar to adsorb metal ions, and then soaks the carbon material adsorbed with metal ions in an aqueous solution containing an organic ligand (2-aminoterephthalic acid), and stirs for a certain period of time to obtain a biochar / MOFs composite material with high loading rate and uniform dispersion. Then, the chelating agent is grafted onto the surface of the composite material by the chemical reaction between NH2 in the MOFs material and COOH in the chelating agent, and a composite material with excellent electrochemical detection performance is prepared. The electrochemical sensor prepared by the composite material synthesized by the present invention has high detection sensitivity and can realize trace detection of Pb ions in water. The present invention solves the problem that biochar-based electrochemical sensors cannot perform trace detection of Pb ions in water.
Owner:QILU UNIVERSITY OF TECHNOLOGY (SHANDONG ACADEMY OF SCIENCES)

Split type motor stator

The utility model relates to a split type motor stator. The split type motor stator has a coil assembly including a plurality of coil strands disposed in the split type motor stator, the split type motor stator including: a first core located on a first side of the coil assembly in a direction of a rotation axis of the coil assembly, and including a receiving groove in which the coil strands are received; the coil stranded wire is inserted into the accommodating groove; and a second core portion located on a second side of the coil assembly and coupled to the first core portion to fix a position of the coil assembly.
Owner:HYUNDAI MOBIS CO LTD

Nano pesticide adjuvant and application thereof

The invention discloses a nano pesticide adjuvant, the nano pesticide adjuvant comprises ulmic acid and a quaternary ammonium salt type cationic surface active agent which is polyquaternium-7, the mass ratio of the ulmic acid to pesticide active ingredients is (1-10): 1, and the quaternary ammonium salt type cationic surface active agent accounts for 0.1-2% of the percentage content of a pesticide preparation; a stable nano-pesticide preparation can be prepared from the nano-pesticide adjuvant, and the nano-pesticide adjuvant is simple in preparation process and suitable for being used in agriculture.
Owner:SHANDONG AGRICULTURAL UNIVERSITY

Polymer, insulin sustained release preparation containing polymer and application

The invention discloses a polymer, the polymer comprises a diphenylboronic acid structural unit capable of being combined with glucose and a hydrophilic polymerizable structural unit, and the diphenylboronic acid structural unit can improve the combining capacity and selectivity of glucose. The invention further discloses an insulin sustained release preparation containing the polymer, the preparation has different insulin release rates under different glucose concentrations, insulin release is accelerated in a hyperglycemia environment to reduce blood sugar, and the preparation can reduce insulin wrong release caused by fructose and other diol substances. The invention also discloses a preparation method of the insulin sustained-release preparation. The insulin sustained-release preparation is prepared by self-assembling negatively charged insulin and positively charged bisphenylboronic acid modified polymer through electrostatic interaction, and the insulin sustained-release preparation has the characteristic of high load rate. The prepared insulin sustained-release preparation can release insulin, and the blood glucose level can be reduced after the released insulin is combined with an insulin receptor in a body.
Owner:NINGBO INST OF MATERIALS TECH & ENG CHINESE ACAD OF SCI +1

CaCO3-based validamycin controlled release preparation and preparation method thereof

PendingCN121926203APromote local oversaturationpromotion and nucleationBiocideFungicidesAcetic acidArginine
The invention discloses a CaCO3-based validamycin controlled release preparation and a preparation method thereof, and the preparation method comprises the following steps: taking glucose, amino acid and water as raw materials, reacting under a microwave heating condition, and standing to obtain carbon dots; wherein the amino acid is one or a mixture of more of lysine, histidine and arginine; the preparation method comprises the following steps: mixing validamycin, water and calcium acetate, stirring, adding carbon dots, and stirring to obtain a validamycin / carbon dot mixed solution; and adding a sodium carbonate aqueous solution into the validamycin / carbon dot mixed solution, stirring, standing, and drying the obtained precipitate to obtain the CaCO3-based validamycin controlled release preparation. The controlled release preparation has the characteristics of high drug loading rate, controllable drug release, simple preparation process and the like, and provides a new strategy for developing CaCO3-based nano pesticides.
Owner:HEFEI INSTITUTE OF PHYSICAL SCIENCE CHINESE ACADEMY OF SCIENCES

Culture medium for efficient genetic transformation of kidney beans and genetic transformation method

The invention provides a culture medium for efficient genetic transformation of kidney beans and a genetic transformation method, and belongs to the field of plant genetic transformation. The culture medium for efficient genetic transformation of kidney beans comprises a co-culture medium and a bud induction culture medium. The preparation method comprises the following steps: dissolving aluminum nitrate nonahydrate and magnesium nitrate hexahydrate, mixing and shearing with a sodium hydroxide solution, centrifuging, washing, adding deionized water, heating, reacting to prepare nano-carrier particles, and supporting titanium dioxide columns among layers of the nano-carrier particles by using tetrabutyl titanate as a raw material through a sol-gel method to prepare the nano-carrier particles. Compared with the prior art, the composite carrier has the advantages that the interlayer spacing of nano-carrier particles is obviously increased, more space is provided for loading ascorbic acid, and the effect of improving the ascorbic acid loading rate is further achieved; therefore, the anti-oxidation persistence of the prepared co-culture medium and bud induction culture medium can be improved.
Owner:WEIKE (QINGDAO) BIOTECHNOLOGY CO LTD

Preparation method of D-mannitol-melamine foam composite solid-solid phase change material

The invention discloses a preparation method of a D-mannitol-melamine foam composite solid-solid phase change material. The preparation method comprises the following steps: cutting melamine foam MF into small blocks; placing the melamine foam sample cut into blocks on a porcelain boat in a quartz tube of a tubular resistance furnace, carbonizing in a nitrogen atmosphere, and cooling to room temperature after carbonization is finished; adding the carbonized melamine foam CF block into molten D-mannitol DM, and carrying out vacuum impregnation in a vacuum drying oven; and taking out the impregnated sample, heating the sample on a heating plate, and removing redundant mannitol on the surface to obtain the D-mannitol-melamine foam. The prepared DM / CF composite material has excellent shape stability, leakage, loss or form out-of-control of the phase change material in the phase change process can be avoided, the safety and reliability of the material are guaranteed, and potential application prospects are provided for the fields of solar energy utilization, industrial waste heat recovery and the like.
Owner:SHANGHAI SECOND POLYTECHNIC UNIVERSITY

Pterostilbene bionic oral nano delivery system based on lactobacillus helveticus exosome as well as preparation method and application of pterostilbene bionic oral nano delivery system

ActiveCN119424367Areduce productivityHigh load rate
The invention discloses a pterostilbene bionic oral nano delivery system based on a lactobacillus helveticus exosome as well as a preparation method and application of the pterostilbene bionic oral nano delivery system. The preparation method comprises the following steps: extracting the lactobacillus helveticus exosome from a lactobacillus helveticus culture solution by adopting a method of combining continuous differential centrifugation and microporous membrane filtration; and mixing the lactobacillus helveticus exosome with pterostilbene, and carrying out ultrasonic treatment and incubation treatment, so as to prepare the lactobacillus helveticus exosome-pterostilbene bionic oral nano delivery system. According to the invention, the lactobacillus helveticus source exosome with the advantages of high yield and expansibility is successfully extracted for the first time, and the clinical limitations of high cost and low productivity of animal source and plant source exosomes as oral delivery carriers are improved; meanwhile, the prepared lactobacillus helveticus exosome-pterostilbene bionic oral nano-delivery system combines the natural characteristics of the exosome and the high biological safety of the probiotics, and can realize the balance of the oral delivery performance and the biological safety of the nano-carrier.
Owner:HEFEI UNIV OF TECH

Power distribution system and server system

Embodiments of this application provide a power distribution system, to implement power supply backup for power distribution equipment, reduce backup costs, and increase a load ratio and power supply conversion efficiency of a power backup device. The power distribution system includes a plurality of power distribution equipments, and the plurality of power distribution equipments are configured to supply power to a plurality of powered devices respectively. First power distribution equipment in the plurality of power distribution equipments includes: a first power module, configured to perform voltage conversion on an input voltage to obtain an output voltage, where the output voltage is a supply voltage of the first power distribution equipment; and a first cascading circuit, configured to connect an output of the first power module to an output of a power module in power distribution equipment in the power distribution system other than the first power distribution equipment, where the first power distribution equipment is any power distribution equipment in the power distribution system. A server system which includes the power distribution system is also disclosed in this application.
Owner:HUAWEI DIGITAL POWER TECH CO LTD

Multi-pole full-connection power transformation and distribution system structure and construction method thereof

The invention relates to the field of power supply and distribution, and discloses a multi-pole full-connection power transformation and distribution system structure, secondary outgoing lines of transformers are constructed into a multi-pole form, each multi-pole branch loop of a secondary outgoing line main loop of each transformer serves as an incoming line power supply to construct a feed bus, and the feed buses and other networking transformers form a full-connection structure. The multi-pole full-connection power transformation and distribution system structure has two structures of a basic type and an extended type, and multiple power transformation and distribution networking system structures such as N + 1, N + 2, N + 3,..., N + n and the like can be constructed. The invention further discloses a composition method and an operation mode of the multi-pole full-connection power transformation and distribution system structure, system redundancy capacity of different levels is provided, different scene requirements are met, and the multi-pole full-connection power transformation and distribution system structure has the advantage that reliability, flexibility and economical efficiency are mutually balanced.
Owner:丁峰

An integrated method for rapid separation and detection of fungal toxins based on nylon-fluorescent metal-organic framework films

The present invention discloses a method for rapid separation and detection of mycotoxins based on nylon-fluorescent metal-organic framework film. The nanofilm is cleaned and dried, and microwave-treated to obtain a nanofilm modified with PDA, which is dissolved in a mixed solution composed of metal ions A, organic ligands B and regulator C, and then placed in a microwave oven for high-temperature heating synthesis, and cleaned and dried to obtain a nanocomposite film loaded with fluorescent metal-organic framework materials, and the mycotoxin solution to be tested is filtered, and the change in fluorescence intensity of the nanocomposite film before and after filtration is measured to determine the corresponding concentration. The present invention solves the problem of poor controllability, realizes the preparation of a stable nylon fiber-metal-organic framework composite film, and the nanocomposite film can directly adsorb and detect mycotoxins in a filtered state, and realizes good practical applications in feed, integrates filtration and detection, and simplifies the problem of complex pre-treatment operations.
Owner:ZHEJIANG UNIV

A crown ether functionalized silica gel material and its preparation method and application

The invention discloses a crown ether functionalized silica gel material and its preparation method and application; the crown ether functionalized silica gel material is prepared by reacting a multifunctional amino functionalized silica gel material with a benzo crown ether derivative with an aldehyde group; or the multifunctional amino functionalized silica gel material is reacted with a benzo crown ether derivative with an aldehyde group, and then reacted with a crown ether compound with an alkenyl group, a carboxyl group or a halogen group; the invention fixes the crown ether on the silica gel material in the form of a skeleton through the reaction of the benzo crown ether derivative with the amino group at the end of the polyamine silane chain in the multifunctional amino functionalized silica gel material, forming a three-dimensional molecular cage structure; and further links the crown ether on the side of the molecular cage, increases the crown ether loading amount, and enhances the binding effect between the material and the target substance. The crown ether functionalized silica gel material of the invention is used as an adsorbent for cesium adsorption, can achieve high adsorption capacity and selectivity, and has excellent cyclic regeneration ability.
Owner:SUZHOU SI-NOVATION NEW MATERIAL TECH LTD

Synthesis method of brivaracetam

The invention relates to the technical field of drug synthesis, and discloses a brivaracetam synthesis method, which comprises: (1) carrying out nitrilase catalysis on 3-cyanocapronitrile to prepare (R)-3-cyanohexanoic acid, carrying out hydrogenation catalysis to obtain (R)-3-aminomethyl hexanoic acid, and carrying out amidation to obtain a compound represented by a formula I; (2) reacting the compound as shown in the formula I with methyl-2-methyl bromobutyrate in an organic solvent in the presence of alkali to obtain a compound as shown in a formula II; and (3) carrying out ammonolysis on the compound as shown in the formula II, and separating a mixture obtained by reaction through chromatography to obtain a brivaracetam product as shown in a formula III. The brivaracetam synthesis process provided by the invention is more convenient, can reduce the cost, is environment-friendly, green and efficient, and is suitable for industrialization.
Owner:ZHEJIANG APELOA JIAYUAN PHARMA +1

Preparation of nano MOF-SIP-coated HP55 oral vaccine applied to streptococcus agalactiae infection of nile tilapia

The invention discloses a preparation method of a nano MOF (Metal Organic Framework)-SIP (Sequence Initicosus)-HP55 oral vaccine applied to streptococcus agalactiae infection of Nile tilapia. The nano MOF-SIP-HP55 oral vaccine comprises MOF-SIP (Sequence Initicosus) nanoparticles and an acid-base sensitive type enteric coating material HP55, wherein the surface of the MOF-SIP nanoparticles is coated with the acid-base sensitive type enteric coating material HP55; the MOF-SIP nano-particles are nano-materials formed by assembling streptococcus agalactiae surface protein SIP and a metal organic framework (MOF) nano-material. The nano vaccine provided by the invention has the advantages of good biocompatibility, degradability, safety, relatively high loading capacity, tolerance to digestion of fish gastric juice, immune response persistence, high effectiveness and the like, so that an effective technical support is provided for research and development of nano vaccines in the future, trend to clinical application and commercialization.
Owner:FUJIAN NORMAL UNIV

A quick-repair expansion joint polyurethane elastomer composition and preparation method thereof

The invention discloses a quick-repair expansion joint polyurethane elastomer composition in the field of polyurethane elastomer and a preparation method thereof, which is prepared from the following components in parts by weight: 53-62 parts of corn stalks, 32-46 parts of diphenylmethane-4,4'-diisocyanate, 7-10 parts of polytetrahydrofuran, 0.5-0.6 parts of pentamethyldiethylenetriamine, 6-9 parts of polyethylene glycol, 1.6-2.2 parts of 4,4'-dicarboxyl diphenyl disulfide, 3.5-5 parts of 1,4-butanediol and 0.9-1.6 parts of modified graphene. The present invention prepares a straw cellulose-polyurethane-graphene composite gel and introduces 4,4'-dicarboxyl diphenyl disulfide to achieve the improvement of the self-repairing effect of the material and the service life.
Owner:HEBEI JINKUN ENG MATERIAL CO LTD

Preparation method of banana nanocellulose-montmorillonite aerogel / paraffin composite phase change material

The invention belongs to the field of textile materials, and particularly relates to a preparation method of a banana nanocellulose-montmorillonite aerogel / paraffin composite phase change material. The preparation method comprises the following steps: by taking green, environment-friendly and low-cost banana raw hemp as a raw material, preparing the nano cellulose-montmorillonite aerogel by a physical and chemical combined method; paraffin is loaded into the nanocellulose-montmorillonite aerogel by adopting a vacuum impregnation method, and the nanocellulose aerogel phase change material capable of releasing heat for a long time is prepared. The preparation method comprises the following steps: (1) preparing banana nano cellulose; (2) preparation of nano cellulose-montmorillonite aerogel; and (3) preparing the nano cellulose-montmorillonite aerogel / paraffin composite phase change material. According to the banana nanocellulose-montmorillonite aerogel / paraffin composite phase change material prepared by the invention, the adopted raw materials are environment-friendly and low in cost; the nanocellulose aerogel is low in density, high in porosity and high in paraffin loading rate; due to the addition of montmorillonite, the heat conductivity coefficient is increased, the photothermal conversion is enhanced, and heat can be released for a long time.
Owner:TIANJIN POLYTECHNIC UNIV +1

A nano desorbent for gas well and a preparation method thereof

ActiveCN120961126Beasily brokenReduce electrostatic attractionOther chemical processesGaseous fuelsActive agentDesorption
The present application belongs to the technical field of oil and gas exploitation, and relates to a nano desorption agent for gas well and a preparation method thereof. The desorption agent uses special pretreated biochar as a core carrier, loads specific proportion of bimetallic oxide nanoparticles, and is supplemented with an environmentally friendly surfactant for surface modification. Through the synergistic effect of nano size effect, catalysis / electron transfer effect of metal oxide, physical adsorption and pore transport effect of biochar, and interfacial tension reduction effect of surfactant, the adsorption energy barrier of gas molecules such as methane on the rock surface is significantly reduced, and the efficient desorption is promoted. At the same time, all components and preparation processes are environmentally friendly and harmless to human body.
Owner:LIAONING QIRUI PETROLEUM TECH CO LTD

Multifunctional gamma-PGA carrier material as well as preparation method and application thereof

The invention discloses a multifunctional gamma-PGA carrier material as well as a preparation method and application thereof, and belongs to the technical field of biological carrier materials. Comprising the following steps: S1, taking a proper amount of beta cyclodextrin and paratoluensulfonyl chloride, dissolving the beta cyclodextrin and the paratoluensulfonyl chloride in a NaOH solution, violently stirring under the reaction condition of 0 DEG C, and performing post-treatment to obtain beta-CD-TS; s2, adding the compound beta-CD-TS obtained in the step S1 into a proper amount of ethidene diamine for reaction, and performing post-treatment to obtain a compound beta-CD-NH2; and S3, activating the beta-CD-NH2 obtained in the step S2, 3-aminophenylboronic acid and 4-dimethylaminopyridine (DMAP) in a reaction bottle by using an N, N-dimethylformamide (DMF) solution, simultaneously taking a proper amount of gamma-PGA and a proper amount of dicyclohexylcarbodiimide (DCC00) in the reaction bottle, activating by using DMF as a solvent, and merging liquids to continue the reaction to obtain a product. The gamma-PGA molecular structure prepared by the invention has high drug loading rate and good physicochemical properties, and can be used in the aspects of drug sustained release, wound tissue repair, biological adhesion, hemostatic, enzyme packaging and the like.
Owner:CHENGDU UNIV