The invention provides a no-solvent hot-melt pressure-sensitive masking tape and a manufacturing process thereof. During a production process, the raw materials are prepared according to the weight percentages that: rubber 10-65%, tackifying resin 20-70%, a softening agent 5-45%, an anti-aging agent 0.2-0.8%, a coupling agent 0.1-0.3%, an inorganic filling material 0-15%, and the like; the raw materials with a precise ratio are added into an extruder, and are subjected to sufficient melt-mixing, such that hot-melt glue is produced; the extruder directly supplies the produced hot-melt glue to a coating device; and the coating device coats the hot-melt glue onto a masking tape paper, such that the no-solvent hot-melt pressure-sensitive masking tape is obtained. According to the invention, the extruder is used for replacing original kneading machine and stirring tank to produce hot-melt glue, such that secondary glue melting is not needed before glue coating. Therefore, glue cohesive strength is ensured, and a problem of supply difficulty of high-viscosity glue is solved. With the process, production numerical control is realized, and production efficiency is improved.