A manual transfer vest which aids in compensating for fatigue, pain, loss of strength, mobility, and energy in the daily life of patients and / or individuals / caregivers assisting them. It comprises soft, lightweight, and preferably washable material that enwraps the patient's torso, and also has at least seven non-adjustable hand-grip lift components with sturdy and durable construction and attachment. In some preferred embodiments, nine hand-grip lift components are used, with six hand-grip lift components preferably situated bilaterally on the vest front, and three hand-grip lift components situated on the vest back. For vest durability during repeated patient lifting, reinforcement lining stitching is secured adjacent to or near at least one end of all hand-grips lift components. Interior adjustment ties, padded neck and armhole openings, mesh fabric, and a collar may also contribute to patient comfort. Overall, the manual transfer vest promotes safety in preventing injuries, thereby reducing medical costs.