74results about How to "Improving the effect of implantation" patented technology

This disclosure is directed toward sealable and repositionable implant devices that are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and / or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant.

The invention discloses a sensor device capable of controlling insertion angle in subcutaneous tissue, the sensor device comprises a fixing base and an inserting base provided with a hard needle tubing through hole and rotatably connected to the fixing base. The sensor device capable of controlling insertion angle in subcutaneous tissue has the advantages that it is convenient to insert the insertion type biosensor into the subcutaneous tissue and adjust the insertion angle of the insertion type biosensor in the skin tissue, so that the insertion type biosensor can have longer effective length in the subcutaneous tissue; the measured data is more accurate and near to the actual data.

This disclosure is directed toward sealable and repositionable implant devices that are provided with one or more improvements that increase the ability of implants such as endovascular grafts to be precisely deployed or re-deployed, with better in situ accommodation to the local anatomy of the targeted recipient anatomic site, and / or with the ability for post-deployment adjustment to accommodate anatomic changes that might compromise the efficacy of the implant.

The invention is applicable to the technical field of medical instruments, and discloses a robot for implanting radioactive particles. The robot comprises an external needle puncture device, an internal needle device, a clip device and a posture control device; the external needle puncture device comprises a first supporting frame and a rotatable external needle puncture tube; the internal needledevice comprises an internal needle and an inner needle driving component, the front end of the internal needle can extend into the external needle puncture tube, and the inner needle driving component is used for driving the internal needle to slide along the external needle puncture tube; the external needle puncture device is connected to the posture control device. The robot for implanting theradioactive particles can automatically and continuously implant the radioactive particles and is high in automation degree and excellent in safety and reliability, extrusion of target tissues (target spots) by the external needle puncture tube can be effectively eliminated by rotation of the external needle puncture tube, puncture positioning precision is higher, radioactive particle implantingeffects are better, and the robot is compact in structure and excellent in application effect.

Methods, systems, and devices for an adaptable blood pump are disclosed herein. The blood pump can be part of a mechanical circulatory support system that can include a system controller and the blood pump. The blood pump can include a rotary motor and a control unit that can communicate with the system controller. The blood pump can determine when communication with the system controller is established or has been lost. The blood pump can retrieve one or several back-up parameters when communication with the system controller has been lost, and can operate according to these back-up parameters.

A method for manufacturing a device for monitoring at least one body function of a user comprising providing an evaluation unit, providing a sensor unit, aligning a connector portion of the sensor unit next to an electric contact pad of the evaluation unit such that the connector portion faces the electric contact pad, providing at least one anisotropic conductive adhesive between the electric contact pad and the connector portion, and bonding the evaluation unit substrate and the connector substrate together, wherein the electric contact pad and the connector portion are pressed together, and wherein an electric connection of the electric contact pad and the connector portion is created via the anisotropic conductive adhesive.

The invention discloses a method for identifying a motion foreground in a video. The method comprises the steps of: acquiring a to-be-processed video frame containing a video implantation target region; determining a corresponding region of interest according to the video implantation target region; for the region of interest, performing rough segmentation on a motion foreground of the region of interest through comparing the foreground and a background; and for a rough segmentation result, performing fine segmentation on the motion foreground of the region of interest through image edge processing, so as to obtain a motion foreground segmentation result. The method can achieve the effect of identifying the motion foreground in the video frame quickly and precisely in real time.

Methods, systems, and devices for an adaptable blood pump are disclosed herein. The blood pump can be part of a mechanical circulatory support system that can include a system controller and the blood pump. The blood pump can include a rotary motor and a control unit that can communicate with the system controller. The blood pump can determine when communication with the system controller is established or has been lost. The blood pump can retrieve one or several back-up parameters when communication with the system controller has been lost, and can operate according to these back-up parameters.

The invention discloses a culture system for the amplification of hematopoietic stem cells of cord blood and applications thereof. The culture system contains a 1640 culture medium, fetal bovine serum (FBS), thrombopoietin, stem cell factor (SCF) and human FMS tyrosine kinase 3 ligand Flt-3L and also contains pleiotrophin PTN. A proper concentration of PTN is added in the existing hematopoietic stem cell medium to prepare the culture system which can support the growth and amplification of the hematopoietic stem cells of cord blood more effectively in vitro and particularly increase the implanting capability of hematopoietic stem cells after being implanted in a receptor obviously and the reconstruction capability of the hematopoietic system. Therefore, new application prospects are opened up for the clinical applications of the stem cells of cord blood.

The invention discloses a sensor device capable of controlling insertion angle in subcutaneous tissue, the sensor device comprises a fixing base and an inserting base provided with a hard needle tubing through hole and rotatably connected to the fixing base. The sensor device capable of controlling insertion angle in subcutaneous tissue has the advantages that it is convenient to insert the insertion type biosensor into the subcutaneous tissue and adjust the insertion angle of the insertion type biosensor in the skin tissue, so that the insertion type biosensor can have longer effective length in the subcutaneous tissue; the measured data is more accurate and near to the actual data.

An apatite / collagen composite powder absorbed and replaced by autogenous bone in the living body, a formable-to-any-shape artificial bone paste comprising an apatite / collagen composite powder and a binder, a method for producing an apatite / collagen composite powder by turning a suspension containing a fibrous apatite / collagen composite to liquid drops and rapidly cooling them, and a method for producing an apatite / collagen composite powder by granulating a blend comprising a fibrous apatite / collagen composite.

The invention provides a preparation method of boron carbide ceramic chips. The method comprises the following steps: (1) preparing 1-2wt% of a graphene solution, adding a dispersing agent, and evenlydispersing in a way of ultrasonic, stirring or ball-milling to obtain a solution containing uniformly dispersed graphene; (2) adding the solution into boron carbide raw material powder, wherein boroncarbide power with average particle size of 3-5mu m is selected as a raw material, 3-4% of graphite powder is added as a sintering additive, and the average particle size of the graphite powder is 1-2mu m; (3) mixing the boron carbide raw material powder with the graphene solution, and carrying out ball-milling to form slurry; (4) granulating and drying to obtain granulated powder; (5) putting the granulated powder into a mould, hot-pressing and sintering.

The invention discloses a dental implant with a porous thread structure. The dental implant comprises a body, wherein threads are arranged on the body, and an edge groove is formed in the threads; a conical-bottom thread hole is formed in the center of the middle upper part of the inside of the body, and the body is a porous body having a porosity of 5% to 20%. The body of the dental implant is designed into a porous structure, so that the elastic modulus of a part, in contact with a bone, of the implant is effectively reduced, thereby significantly reducing or eliminating a stress shielding phenomenon, solving the problem that the dental implant is loosened by the stress shielding phenomenon, enhancing the binding stability of the implant and the bone, inducing bone tissue to grow into pores of the implant so that the biological fixation is formed between the implant and the bone tissue, improving the implanting effect of the dental implant, and improving the service safety; meanwhile, the biomechanical properties of the implant and the part in contact with the bone are matched, the service life of the dental implant is prolonged, and the production cost is reduced.

The invention provides a method for preparing a boron-titanium carbide alloy composite armor. The method comprises the following steps: (1) preparing 1-2wt% of a graphene solution, adding a dispersingagent for uniform dispersing, and thus obtaining a graphene uniformly-dispersed solution; (2) adding in boron carbide raw material powder, selecting boron carbide powder with the mean particle size being 3-5um as a raw material, and adding 3-4% of graphene powder as a sintering aid, wherein the mean particle size of the graphene powder is 1-2um; (3) mixing the boron carbide raw material powder and the graphene solution for ball-milling to form slurry; (4) pelletizing and drying, and thus obtaining pelletizing powder; (5) putting the pelletizing powder in a mould, and conducting hot-pressing sintering; (6) splicing ceramic chips into a ceramic plate, placing the ceramic plate in the mould, preheating, and taking out to put in a pouring trough; (7) heating a smelting furnace to a certain temperature, and pouring titanium alloy after completely melted to the surrounding of the ceramic plate; after solidifying molten titanium alloy, realizing the packaging of metal to ceramic materials.

The invention discloses a radioactive particle automatic implanting device. The radioactive particle automatic implanting device includes a radioactive particle storage device, a radioactive particle implanting needle, a push rod, a driving cylinder and a main controller, wherein the radioactive particle storage device is internally provided with a radioactive particle storage cavity, and a radioactive particle delivery channel is formed in the bottom of the radioactive particle storage cavity; a radioactive particle implanting channel is horizontally formed in the lower end of the radioactive particle storage device, and a first end of the radioactive particle implanting channel is an implanting needle insertion end; a second end is a push rod insertion end, and a radioactive particle lead-in mouth is formed in the part, close to the implanting needle insertion end, of the inner top surface of the radioactive particle implanting channel; a radioactive particle slide path is arranged between the radioactive particle lead-in mouth and the bottom of the radioactive particle delivery channel, and the radioactive particle implanting needle is connected with the implanting needle insertion end; the front end of the push rod is inserted into the push rod insertion end, and the rear end is connected with the driving cylinder. The radioactive particle automatic implanting device has the advantages of automatically implanting large-batch radioactive particles into a tumor part of the body of a patient, and the use effect is good.

The invention discloses a bone implant, which comprises a porous material, a metal stem which is contained in the porous material, as well as growth factors and medicines which are contained in the bone implant, wherein the porous material is an integrated body; the porous material is a multi-stage porous material which includes at least two stages, and pores of the minimum stage are nano-scale pores; and pore cavities of various stages mutually communicate and the pores cavities in each of various stages also mutually communicate. The bone implant provided by the invention, is integrally fixed and strong in supporting capacity in the initial stage of implantation, so that a surgery becomes simple to operate and short in duration; more growth factors and medicines can be stored, so that the bone implant is more conducive to cell adhesion, differentiation and migration, and the bone implant is beneficial for promoting cell growth and accelerating tissue regeneration; and the bone implant is beneficial for rapid and sufficient transmission of tissue fluid and metabolites and for smooth growth of tissues.

The invention relates to a plugging stent for a left auricle. The plugging stent comprises a reticular body and a tail connected with the reticular body, wherein the tail is overturned inwards to forma blunt shape, so that the contact area between the tail and the left auricle is enlarged, the situation that left auricle walls and internal tissue are damaged by the tail end of the stent in the transplanting process and after transplanting is avoided, the damage of the surgery to the patient is reduced, simultaneously, risks of hydropericardium, perforation and the like can also be avoided, and the safety of the surgery operation is higher; and in addition, the maneuverability of the plugging machine is better, and under the situation that the transplanting position is not ideal, the transplanting position can be adjusted only through propelling the plugging machine, so that the operation difficulty is reduced, and the medical care effect is improved.

The present invention provides an intraoperative stent delivery system and an intraoperative stent system. The intraoperative stent includes a main body stent and a side branch stent arranged on the main body stent and extending outward. The intraoperative stent delivery system includes a main body an inner lining and a side branch inner lining arranged on the main body inner lining, the side branch bracket is configured to be sleeved on the side branch inner lining, the main body bracket is configured to be sleeved on the main body inner lining, and the side branch The inner liner is oscillatingly arranged on the main body inner liner to synchronously drive the side support bracket to swing relative to the main body support. In the present invention, by setting the side branch lining that can swing relative to the main body lining, the side branch stent can be swayed synchronously relative to the main body stent, which facilitates alignment and easy implantation of the side branch stent and the left subclavian artery during operation, and avoids thoracotomy The time of freeing and suturing the left subclavian artery in the operation is too long, which increases postoperative complications, reduces the difficulty of operation, shortens operation time, and expands the scope of surgical indications.

The invention adopts addition of graphene to toughen boron carbide ceramic. The mechanism of the graphene reinforcing and toughening is crack deflection, branch, bridge connection, fracture, pulling out and the like. Different from the one-dimensional toughening of fibers, nanotubes, whiskers and the like which are aggregated easily in the past, the graphene is a two-dimensional material, can significantly reduce the mutual attraction among graphene sheets to avoid agglomeration through surface modification and decoration, and has very good dispersity and stability in some liquid mediums. Forexample, the surface of oxidized graphene contains a large amount of oxygen-containing functional groups such as hydroxide radicals, carboxyl and the like, and a stable and disperse graphene solutioncan be prepared; the graphene solution is mixed with ceramic matrix slurry, a graphene ceramic mixed raw material with a good implantation effect can be obtained, therefore, the reinforcing and toughening effects of the graphene ceramic mixed raw material are relatively stable, and the technological feasibility is better.

The embodiment of the invention discloses a multimedia file processing method and device, a terminal device and a medium. The method comprises the following steps: obtaining a target frame image in avideo; identifying at least one line segment included in the target frame image, further screening a multimedia file region edge line segment from the at least one line segment, determining a multimedia file implantation region in the target frame image based on the multimedia file region edge line segment, and further filling a multimedia file material in the multimedia file implantation region.According to the embodiment of the invention, the multimedia file implantation area of the target frame image in the video is determined more accurately through a line segment detection mode, and themultimedia file implantation effect of the video is improved.

The invention provides a 3D printing skin and a preparation method thereof. The 3D printing skin comprises a skin layer made through 3D printing and multiple micro-needles, the micro-needles are embedded in the skin layer, first ends of the micro-needles penetrate into or penetrate through the surface of the skin layer, and second ends of the micro-needles approach, penetrate into or penetrate through the bottom face of the skin layer. Each micro-needle comprises at least one passage arranged between the first end and the second end. The preparation method comprises the steps of3D scanning andmodeling, 3D layered printing and the like. The 3D printing skin completely fits the damaged part of human skin, andthe material conveying function is achieved.

The invention provides an ion implantation method used for implanting ions into a target. The ion implantation method comprises the step of implanting multiple ions into the target by using a rotating target during constant speed scanning; or implanting the multiple ions into the target by using a variable speed under the premise that the target is not rotated. Ion implantation result with special dose distribution can be obtained without need of providing ion beams with uniform concentration distribution; the process time can be reduced; and the process yield can be increased.

The invention discloses a titanium alloy surface collagen coating loaded with antibacterial polypeptides and a preparation method of the coating. An electrostatic spraying technology is also used, thecollagen coating loaded with the antibacterial polypeptides is simultaneously constructed on the surface of porous titanium alloy, the process is simple and convenient, and the spraying efficiency ishigh. Dopamine is oxidized to form polydopamine which has good adhesion, combination of the coating and a titanium alloy matrix can be enhanced, the coating is not likely to fall off, and the coatingcan coexist with a micro-arc oxidation structure on the surface of the porous titanium alloy; meanwhile, the antibacterial polypeptides are loaded on the surface of the titanium alloy; the collagen coating loaded with the antibacterial polypeptides can induce generation of bones and cartilage, more stable chemical bonding and higher biological activity are provided for the titanium alloy implants, the collagen coating is more beneficial for ingrowth of new bone issue, a good antibacterial property is achieved, the infection risk caused by implantation of the titanium alloy can be effectivelyreduced, and the implantation effect is improved.

The invention provides an artificial cochlea pre-bent electrode implantation device, which is characterized in that a hard electrode support piece is arranged in an artificial cochlea pre-bent electrode and can be taken out from a first end of the artificial cochlea pre-bent electrode, and the implantation device comprises an electrode guide mechanism used for supporting the artificial cochlea pre-bent electrode and guiding the artificial cochlea pre-bent electrode; a pre-bent electrode control mechanism used for clamping and driving the artificial cochlea pre-bent electrode to move towards the second end of the artificial cochlea pre-bent electrode; and a supporting piece control mechanism, wherein the first end of the supporting piece control mechanism is fixedly connected with the electrode guide mechanism, and the supporting piece control mechanism is used for clamping the electrode supporting piece located outside the artificial cochlea pre-bent electrode and driving the electrodesupporting piece to move towards the first end of the artificial cochlea pre-bent electrode.

The invention provides a boron carbide-titanium alloy composite armour which comprises a boron carbide ceramic plate and a titanium alloy. The ceramic plate is wrapped with the titanium alloy, and theboron carbide ceramic plate is formed by splicing boron carbide ceramic pieces which are formed by hot pressing of boron carbide ceramic materials. The boron carbide ceramic materials comprise boroncarbide ceramic base bodies and graphene. The graphene is dispersed in the boron carbide ceramic base bodies. The graphene is evenly dispersed in boron carbide powder, then hot-pressing sintering is adopted, the bending strength is improved from about 350 Mpa to 500 Mpa or above, the titanium alloy for boron carbide ceramic is poured, and an overall structure that the four faces of the titanium alloy are wrapped with boron carbide is formed.

The invention discloses an orthopedics department net molding device, and relates to the technical field of medical apparatuses and instruments. The orthopedics department net molding device comprisesa net pipe with the upper closed end, an absorbable flexible layer wrapping the net pipe, an inner pipe and a cover cap, wherein the net pipe comprises a plurality of annularly-distributed deformation strips; the inner pipe is arranged in an inner cavity of the net pipe and used for guiding a filler into the inner cavity of the net pipe, the upper end of the inner pipe is connected with the upperend of the net pipe, and the length of the inner pipe is smaller than that of the net pipe; the cover cap is used for connecting the lower end of the net pipe with the lower end of the inner pipe andblocking he lower end of the net pipe. According to the orthopedics department net molding device, an ingress pipe can feed the net pipe into the portion, needing to be opened, of the centrum, and atraction rope is pulled so that the net pipe can expand so as to open the centrum. Meanwhile, the ingress pipe can fill the net pipe with bone cement or bone blocks. When the orthopedics department net molding device is in use, only few auxiliary tools are needed, operation is easy, and the operation time can be greatly shortened.

The invention discloses a human amniotic membrane-derived mesenchymal stem cell pretreatment method which comprises the following steps: respectively performing separate subculture on an AMSC and an AEC and collecting the AMSC in a P10 generation and the AEC in a P5 generation; performing indirect co-culture treatment on the AMSC in the P10 generation and the AEC in the P5 generation; or enablingan AEC in a P3 generation to be used for preparing a conditioned culture medium and then performing condition culture on the AMSC in the P10 generation; collecting the treated AMSC to obtain the pre-treated AMSC. The human amniotic membrane-derived mesenchymal stem cell pretreatment method disclosed in the invention has the benefits that the stable cytological characteristic and the good proliferative activity of the AMSC can be maintained, so that the quality and the quantity of the MSCs required for clinical application are ensured; the AMSC homing and the number of implants in vivo are increased, so that the quantity of the cells required for treatment can be met; the method is simple and convenient, and due to the characteristic of low cost, the use cost is effectively reduced; meanwhile, the method is good in safety and free from obvious toxic and side effects and has important practical significance in the clinical application of the AMSC and the improvement in the success rate and the curative effect of HSCT.

The invention relates to the technical field of biomaterials, and relates to a preparation method for a bone repair material. The bond repair material is composed of silk fibroin and decalcified bone matrix. A salting-out process is employed for preparing the bone repair material by combining silk fibroin and decalcified bone matrix. The preparation method helps to keep the bone induction and bone conduction capabilities of decalcified bone matrix, and helps to improve the mechanic properties of the bone repair material. The prepared bone repair material has good promotion capability on bone regeneration and excellent mechanical properties, and is substantially improved in shape keeping capability and implanting capability.

Aspects include methods of fabricating antibacterial surfaces for medical implant devices including patterning a photoresist layer on a silicon substrate and etching the silicon to generate a plurality of nano-pillars. Aspects also include removing the photoresist layer from the structure and coating the plurality of nano-pillars with a biocompatible film. Aspects also include a system for preventing bacterial infection associated with medical implants including a thin silicon film including a plurality of nano-pillars.

The invention discloses a preparation method of natto. The preparation method mainly comprises the following steps: firstly, pretreatment of raw materials; secondly, preparing a green body; thirdly, carrying out first-time inoculated fermentation; fourthly, carrying out second-time inoculated fermentation; fifthly, carrying out third-time inoculated fermentation; sixthly, taking out briquettes inthe fifth step, crushing, drying in air, tabletting and packaging to obtain a finished product. The preparation method disclosed by the invention is simple and easy to operate; by preparing the greenbody for three times and carrying out inoculated fermentation for three times, the content of nattokinase is surged to 10,000 to 50,000 FU from 2,000 to 4,000 FU in a traditional method and the content of bacillus natto is increased from 3 billion / g to 7 billion / g or above; the produced natto has the advantages of high content of active ingredients and good quality.