22 results about "Seed Implantation" patented technology

The utility model relates to the technical field of treatment auxiliary instruments, in particular to a support for an anti-radiation bed used after 125 iodine particle implantation, which comprises a first anti-radiation component provided with a first lead sheet. The second anti-radiation assembly is provided with a second lead sheet, and one end of the first anti-radiation assembly is connected with one end of the second anti-radiation assembly through an adjusting assembly; and the lead curtain assembly is slidably mounted at the end part of the first anti-radiation assembly and the end part of the second anti-radiation assembly on one side opposite to the adjusting assembly. The utility model is favorable for reducing radiation and reducing the weight burden of a patient.

The invention discloses a clinical prediction model construction method and system for treating oligometastatic non-small cell lung cancer through radioactive particle implantation, and relates to the technical field of medical model construction, and the method comprises the steps: obtaining patient data, taking survival time as a main endpoint event, employing a Cox regression model to carry out single-factor analysis on factors affecting patient prognosis, and obtaining a single-factor analysis result; determining the relationship between each clinical feature and survival time, and incorporating the important factors influencing the prognosis into multi-factor Cox regression analysis to determine independent risk factors influencing the survival prognosis of the patient; generating a first clinical prediction model according to each independent risk factor nano-construction; cD3 + AC, CD4 + AC, CD8 + AC, combined treatment, complete treatment and the number of metastatic lesions are taken as variables together to be included in construction of a clinical prediction model, and a second clinical prediction model is manufactured and generated. Independent risk factors influencing the prognosis of a radioactive particle implantation treatment few-metastatic NSCLC patient are confirmed, the clinical prediction model is established, the treatment prognosis can be accurately predicted, and the treatment cost is reduced. And screening of dominant benefit people is facilitated.

The utility model discloses an iodine-125 particle implantation device which comprises an implantation assembly and a storage assembly, the implantation assembly comprises a connecting box, one side of the connecting box is provided with a catheter sheath communicated with an inner cavity of the connecting box, the other side of the connecting box is provided with a fixing cylinder communicated with the inner cavity of the connecting box, and a particle push rod is arranged in the fixing cylinder in a sliding mode. A push handle is fixed to the end of the particle push rod, and the outer side of the particle push rod is sleeved with a reset spring located between the connecting box and the push handle. According to the iodine-125 particle implantation device, after a medical worker implants a single iodine particle through the particle push rod, the particle push rod can be automatically reset and does not need to be pulled back by the medical worker, the implantation device is convenient to use, meanwhile, a plurality of iodine particles can be stored in the storage box, the iodine particles do not need to be supplemented repeatedly, the implantation efficiency of the implantation device in use is improved, and the medical worker can conveniently use the implantation device. And the iodine particles can be automatically supplemented through the arranged pushing assembly, and implantation of the iodine particles is facilitated.

The present application relates to the field of medical devices, and discloses a double-cavity particle implantation needle, which comprises an outer needle tube and an inner push needle, the outer needle tube is provided with an implantation cavity which penetrates through in the axial direction, and an auxiliary cavity is further arranged in the tube wall of the outer needle tube, the auxiliary cavity is provided with an opening at one end away from the outer needle tip, and the auxiliary cavity is communicated with the implantation cavity at the position of the outer needle tip or the position close to the outer needle tip. The double-cavity particle implantation needle with the above structure can timely discharge the air in the implantation cavity during the implantation process, avoid the air from being hit into the tissue to cause the problems of inaccurate particle implantation position and particle gathering, and can timely find the bleeding condition and perform timely hemostasis treatment, thereby improving the safety and efficiency of particle implantation, and avoiding the problems of significant decrease in efficiency and excessive radiation of doctors caused by bleeding to wash out the particles during the particle implantation process.

The invention provides an iodine-125 particle implantation device for clinical tumor treatment, the iodine-125 particle implantation device comprises a fixing frame, a detection module and an implantation module are arranged on the side surface of the fixing frame, the detection module comprises a positioning assembly, a detection assembly and a filling assembly, the positioning assembly comprises an adjusting plate capable of moving up and down, and a mounting frame is arranged below the adjusting plate. According to the iodine 125 particle implantation device for clinical tumor treatment, in the iodine 125 particle implantation process, the implantation position and the implantation depth of iodine 125 particles can be automatically detected through the arranged detection module, the detection module can be automatically matched with the implantation module for use, meanwhile, when the detection module is used, automatic coating and filling of a coupling agent at a detection probe can be achieved, and the detection efficiency is improved. In addition, the implantation position of the implantation module can be automatically adjusted according to the arranged implantation point positions, and the needle feeding requirements when the iodine 125 particles are implanted at different positions are met.

The invention discloses a chemotherapeutic drug local sustained-release particle and an application method thereof, and belongs to the technical field of medical health, the chemotherapeutic drug local sustained-release particle comprises a therapeutically effective amount of a chemotherapeutic drug, a developer and an inert sustained-release material; the sustained-release material is uniformly fused with the chemotherapeutic drug and the developing agent in a liquid state and then is cured and molded into solid particles, and the particle size is that the length is 5mm and the diameter is 0.8 mm; the particles provide sustained drug release for more than 24 hours after being implanted into tumor tissue. Compared with the prior art, the method has the advantages that the local sustained-release particles with high drug concentration are planted in the preset position in the tumor, and the drug injury in the tumor for about 24 hours and 30 days can be achieved under the assistance of the sustained-release material and the iodine agent, so that the precise treatment of the chemotherapeutic drug is improved; through precise release of chemotherapeutic drugs, local high-concentration damage of tumor tissues and low-concentration residues of the whole body, adverse reactions of patients and side reactions generated by the drugs can be effectively reduced, and pain of the tumor patients is reduced.

The application discloses a prostate cancer lesion-based intelligent diagnosis auxiliary method and system and a storage medium, relates to the tumor treatment data processing technical field, and comprises the following steps: acquiring current patient case data and image data of a lesion site; searching for and acquiring reference image data sets, statistically analyzing the probability of the lesion tissue appearing at different positions in space based on the reference image data sets, and generating a probability distribution graph of the lesion tissue; calculating and generating a radiation dose distribution graph of the three-dimensional space of the current lesion area according to particle implantation site coordinates; and determining implantation coordinates of superimposed particles according to the probability distribution graph and the radiation dose distribution graph, and marking the implantation coordinates in the image data of the current patient. Through the above scheme, the implantation coordinates of the superimposed particles are determined, the implantation positions of the radioactive particles are more suitable for the distribution of the lesion tissue, the cancer cells of the lesion tissue are killed, the spread of the cancer cells is slowed down or even blocked, and the treatment effect is improved.

The invention discloses a radioactive particle protection implanting device for tumor treatment. The radioactive particle protection implanting device comprises an implanting gun body, a puncture needle, a loading assembly and a push rod matched with the puncture needle. The loading assembly is detachably installed on the surface of the implantation gun body, a bullet loading box and a rotatable rotating wheel are arranged in the loading assembly, a loading groove is formed in the periphery of the rotating wheel, and through holes are formed in the surface of the shielding protection plate and used for achieving one-by-one alignment and shielding protection of radioactive particles. A trigger, a fixed assisting block, a movable assisting block, an elastic piece and an engaging lug are arranged in the implantation gun body, the push rod is driven to linearly advance through the connecting rod and the sliding lug, one-way limiting is achieved under the clamping action of the engaging lug, and reverse sliding of the push rod is prevented. The guide cylinder is used for guiding the push rod to enter the puncture needle and accurately implanting particles into tumor tissue. The device is provided with a rotary missile cabin type protection structure, an anti-non-return gun type propelling structure and a detachable modular loading assembly, radiation leakage can be effectively avoided, it is guaranteed that particle implantation is accurate and reliable, replacement is rapid, and the device has high clinical application value.

1. Name of the product in this design: Prostate puncture stent. 2. Purpose of this design: To support the puncture template and ultrasound probe during prostate radioactive particle implantation surgery. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The utility model belongs to the technical field of medical instruments, and particularly relates to a radioactive particle implanting device which particularly comprises a needle tube, a sharp-head needle core, a blunt-head needle core, a flat-head needle core and a particle implanting device, the sharp-head needle core is used for puncturing skin, the blunt-head needle core is used for puncturing fragile tissue, the flat-head needle core is used for pushing in particles, and the particle implanting device is used for implanting particles. The needle head of the flat-head needle core is flush with the front end of the needle tube, the tail end of the flat-head needle core is connected with the inlet of the needle core in a clamped mode, it is guaranteed that radioactive particles are accurately fed into tumor cells of tissue to be treated, and meanwhile the length of the needle point of the blunt-head needle core is set to be equal to the height of the implanted particle sealing tube, so that the needle head of the blunt-head needle core is the accurate implantation position of the radioactive particles. And accurate positioning of an implantation part can be further realized, and the device can be widely applied to treatment of tumor cells.

The invention discloses a preparation method and application of a template for particle implantation, relates to the technical field of radioactive auxiliary equipment, and is characterized in that the template for radioactive particle implantation is provided, and meanwhile, the invention further discloses the preparation method of the template. In addition, the template can also be used for measuring whether dose rate distribution after particle implantation conforms to a preset value or not in actual use, so that whether a particle implantation operation is successful or not is judged. The basic structure of the template comprises a flexible grid plate and a gel layer, the flexible grid plate is made of a rubber material containing bismuth, tungsten and tantalum powder, and the gel layer is made of a fluorescent composite material containing ZnS powder.

The invention discloses an intelligent diagnosis auxiliary method and system based on a prostatic cancer focus and a storage medium, and relates to the technical field of tumor treatment data processing, and the method comprises the steps: obtaining the case data of a current patient and the image data of a focus part; searching and acquiring a reference image data set, counting the occurrence probability of the focus tissue at different positions in the space based on the reference image data set, and generating a probability distribution diagram of the focus tissue; calculating and generating a radiation dose distribution diagram of a three-dimensional space of the current focus area according to the particle implantation site coordinates; and according to the probability distribution diagram and the radiation dose distribution diagram, determining implantation coordinates of the superposed particles, and labeling the implantation coordinates in the image data of the current patient. According to the scheme, the implantation coordinates of the superposed particles are determined, so that the implantation positions of the radioactive particles are more matched with the distribution of focus tissues, cancer cells of the focus tissues can be killed, diffusion of the cancer cells is slowed down or even blocked, and the treatment effect is improved.

The invention discloses a multi-channel core pulling mechanism which comprises a core pulling mechanism body and a moving platform, and the moving platform can enable the core pulling mechanism body to be in butt joint with the tail portions of different needle cores one by one by adjusting and controlling the positions and / or the distances between the core pulling mechanism body and the tail portions of the different needle cores. The core pulling mechanism pulls out the needle core after being in butt joint with the corresponding needle core. According to the invention, the needle core can be pulled out before particle implantation, so that a radioactive source implantation machine is prevented from being always rigidly connected with a puncture needle, and then radioactive particle implantation is carried out immediately; the normal operation is ensured on the premise of avoiding scratching a patient; the positions and / or the distances between the core pulling mechanism and the tail parts of the different needle cores are regulated and controlled through the motion platform, so that automatic butt joint of the core pulling mechanism and the tail parts of the different needle cores is realized, the core pulling mechanism can pull out the needle cores after being in butt joint with the tail parts of the different needle cores one by one, and multi-channel core pulling is realized.

The present invention belongs to the technical field of tumor radiotherapy dose calculation and optimization, and provides a particle source distribution method and system for particle implantation therapy. The method includes the following steps: obtaining medical images of the tumor and surrounding tissue; determining the size data of the tumor based on the medical images, and calculating the number of particles to be implanted based on the size data; and determining the optimal source distribution position of the particles through a hybrid optimization algorithm based on a standard dose template determined by the radiation dose of a single particle. The advantage of the present invention is that when the particles are initially distributed, an abstract dose template is used to make the particle arrangement more reasonable and orderly, further reducing the computational cost of the algorithm and improving the quality of algorithm optimization; at the same time, the radiation of the particles to the surrounding area is pre-packaged in the system as a standard dose template, which can be used at any time, eliminating the need for complex calculations and only requiring an almost cost-free addition calculation to determine the optimal source distribution position.

The utility model relates to the technical field of medical treatment, and discloses a detachable radioactive 125I particle strip which comprises an implantation tube, the implantation tube is of a cavity structure with one closed end, particles are packaged in the implantation tube, the other end of the implantation tube is open, and a tube sealing piece used for sealing the open end of the implantation tube is installed at the open end of the implantation tube. A pushing device is detachably and fixedly connected to the end, away from the implanting pipe, of the pipe sealing piece and comprises a connecting piece, the connecting piece is detachably and fixedly connected with the pipe sealing piece, a horizontally-arranged push rod is fixedly connected to the end, away from the pipe sealing piece, of the connecting piece, and the center circumference of the push rod in the length direction is parallel to the central axis of the extending direction of the implanting pipe; and a guide device is also arranged at the front end of the implantation tube. The push rod is arranged on the particle strip, so that medical staff can accurately grasp the position of the particle strip in the process of implanting the particle strip, and the implantation accuracy of the particle strip is improved; the pipe sealing piece is detachably and fixedly connected with the connecting piece, so that the push rod is released.

This utility model relates to a radioactive particle implantation device for tumor treatment, belonging to the field of medical device technology, and solves the technical problem of push-and-jam during the delivery of radioactive particles in the prior art. This utility model includes a puncture needle, a receiving cavity, a particle boat, and a push-and-jam assembly. The particle boat includes a particle sleeve, a stabilizing sleeve, and a push-and-jam cover. The particle sleeve has a receiving space to accommodate the radioactive particles, directly carrying the radiation source and protecting the particles from mechanical damage during delivery. The stabilizing sleeve keeps the particle sleeve and the radioactive particles it carries always in the center of the receiving cavity, avoiding delivery jamming due to skewness. By coordinating the particle sleeve, stabilizing sleeve, and push-and-jam cover, the radioactive particles do not directly contact the inner wall of the receiving cavity, thereby reducing frictional resistance. The particle sleeve is always in the center of the receiving cavity, reducing unilateral friction between the particle sleeve and the inner wall of the receiving cavity, thus reducing the occurrence of push-and-jam during the delivery of radioactive particles.

1. The name of the design product: particle implanter. 2. The use of the design product: for matching implant tube to realize positioning stability of radioactive particles, thermotherapy particles. 3. The design points of the design product: in shape. 4. The picture or photo that can best show the design points: perspective view 1.

The present application relates to the field of medical radiation physics and brachytherapy, and discloses a DVH reverse planning method based on case priori library and adaptive weight search, comprising the following steps: S1, case priori library construction and initial plan generation: extracting key features and corresponding "high-quality seed arrangement mode" from the past clinically recognized high-quality iodine-125 particle implantation treatment cases to construct the case priori library, after extracting the key features of the new case, S2, DVH error driven weight adaptive outer ring, S3, short-range inner ring search of maintaining existing optimizer, the present application is composed of three parts of case priori library construction and initial plan generation, DVH error driven weight adaptive outer ring and short-range inner ring search of maintaining existing optimizer, can effectively improve the planning efficiency, enhance the planning stability and reproducibility, improve the planning accuracy, have the cross-case migration ability, strong compatibility and low implementation cost.

A method of inserting brachytherapy seeds into a body organ includes grasping a body organ between a frame defining a large central hole and an additional element. A grid defining a plurality of apertures adapted to receive elongate applicators is placed on one side of the body organ. A plurality of applicators are passed through apertures in the first and second grids and through the body organ. The brachytherapy seeds are anchored in the organ through the frame.

The application discloses an internal radioactive source bone prosthesis and a manufacturing method thereof. The internal radioactive source bone prosthesis comprises a prosthesis body and radioactive particles, the prosthesis body is arranged with a plurality of reserved holes for the radioactive particles, and the radioactive particles are arranged in the reserved holes for the radioactive particles. The shape of the prosthesis body is the same as that of the healthy bone of a resected section, and the arrangement mode of the radioactive particles is determined according to the size, shape and distribution of residual tumor tissues after the resection of the tumor section. The application designs and manufactures a personalized prosthesis for replacing the bone of the tumor section by means of machining or 3D printing technology, the prosthesis is arranged with corresponding reserved holes according to the position of the tumor, the radioactive particles are accurately embedded in the reserved positions during the operation, so that the problem of insufficient implantation position accuracy of the radioactive particles is solved, the size of the reserved holes is consistent with that of the selected radioactive sealed seed source, and the fixing problem of the particle implantation is solved. The process is completed at one time and does not need to be taken out subsequently, so that the operation process is greatly simplified.

The invention provides an iodine 125 particle implantation radiation protection simulation training method. The method comprises the following steps: acquiring and analyzing simulation radiation dose data to obtain implantation operation parameters, radiation safety parameters of each stage and clinical scene parameters; judging whether the current stage is a protection intensified training stage, if not, collecting radiation monitoring data according to a basic protection mode to form radiation safety parameters, and inversely analyzing all the parameters into simulation radiation dose data to be input into a simulation operation end; if yes, the radiation safety parameters are analyzed into monitoring data of the reinforced protection structure, the monitoring data are compressed to serve as parameters of the current stage, and then the monitoring data are inversely analyzed into simulation radiation dose data to be sent to nodes of the next stage. The reinforced protection structure is realized by dividing a basic protection monitoring field into data segments, and redundant data are deleted by comparing the difference of the data segments in adjacent stages and marking the same segment with a flag bit during compression. The real-time performance and the resource utilization rate of simulation training can be improved.

The invention relates to the technical field of medical instruments, in particular to a radioactive particle and bone cement injection device which comprises a tube seat and a pushing injection tube fixed to the bottom of the tube seat, and the tube seat is provided with a radioactive particle filling mechanism and a bone cement injection opening. And the injection pipe comprises a radioactive particle channel and a bone cement channel which are respectively communicated with the radioactive particle filling mechanism and the bone cement injection port. Combined use of radiation particle implantation and bone cement injection in the vertebroplasty can be achieved, and the device is suitable for vertebral tumor treatment.