72 results about "Tumor biopsy" patented technology

Multi-modal approaches to predict tumor immune infiltration are based on integrating gene expression data and imaging features in a neural network-based framework. This framework is configured to estimate percent composition, and thus immune infiltration score, of a patient tumor biopsy sample. Multi-modal approaches may also be used to predict cell composition beyond immune cells via integrated multi-layer neural network frameworks.

The invention discloses a body surface tumor biopsy sampler, which comprises a holding sleeve, a pressing handle, a stable ring and a sampling head. A pair of vertical connecting rods are installed on the outer surface of the holding sleeve, and the connecting rods The bottom is jointly connected with a horizontal stable ring, the inside of the holding sleeve is provided with a vertically penetrating sliding channel, the middle of the pressing handle is symmetrically fixed with lower pressing blocks on both sides, and the holding sleeve passes through the sliding channel It is sleeved outside the pressing handle, and the side of the lower pressing block is in contact with the inner wall of the sliding channel. The pressing handle is covered with a spring. The upper surface of the platform extending from the inner lower part of the pipe to the central axis is abutted and connected. The body surface tumor biopsy sampler has a simple structure, strong integrity, can be operated with one hand, reduces the damage caused by human factors in the sampling process, is more stable, is simple and convenient to replace the sampling head, and has popularization value.

The invention discloses a tumor biopsy sampling device for medical clinic. The device comprises a sampling device body and a sampling cylinder, a storage box is fixedly arranged on the surface of theupper end of the sampling device body, a hydraulic pump is fixedly arranged on the surface of the lower end in the storage box, a hydraulic rod is arranged on one side of the hydraulic pump in a transmission manner, a supporting plate is fixedly arranged at one end of the hydraulic rod, a sampling cylinder is fixedly arranged at one end of the supporting plate, and a plurality of universal wheelsare fixedly arranged on the surface of the lower end of the sampling device body. A second stepping motor is started again to drive a needle cylinder outer sleeve hemming pressing plate to continuously descend, a sampling needle cylinder body compresses a spring, the needle head is pierced into tumor, then the compressing is stopped, at the moment, a driving motor drives an electric push rod to contract, the sampling needle cylinder pressing rod cap is clamped at the lower end of the sampling needle cylinder pressing rod cap, a piston rod is lifted and pulled to move, a sample is extracted, once the operation fails, the other needle head can be rapidly reset and replaced for sampling, shaking is avoided, the success rate is high, and the pain of a patient is reduced.

The invention discloses a device used for preventing tumor spreading after bone neoplasms biopsy, belonging to the technological field of medical instruments, which comprises a plugging body used for plugging biopsy needle passage after biopsy is made; wherein, the plugging body is made of water absorbing expandable material; a plurality of screw threads are arranged at outer surface; one end of the plugging body is plugging end; the maximum diameter of the plugging end is smaller than the diameter of the biopsy needle passage; the other end of the plugging body is an operation end; a jack or an inserting handle grafting the operation wrench along axial direction of the plugging body is arranged on the operation end; maximum diameter of the operation end is bigger than the diameter of the biopsy needle passage; central section of the plugging body is inner concave type connection rod; smooth transition is adopted between the connection rod and the plugging end and the operation end; an anti-cancer drug layer is coated on the plugging end and is used for plugging the needle passage after biopsy is made. The device used for preventing tumor spreading has the advantages of preventing tumor from flowing out from the needle passage to the peripheral of puncturing site and from causing locally spreading and metastasizing, having simple structure and convenient operation.

The invention relates to a novel detachable image-guided puncture device and a production method and application thereof. The device can be directly used for directional positioning of tumor ablation, percutaneous puncture tumor biopsy, intra-tumor intrathecal injection, intervertebral disc puncture decompression, intervertebral disc puncture ablation and the like and can be used for focuses with the depth being more than 10cm. The device can be used for performing next clinical operation flexibly and is more convenient for radio-frequency ablation and seed implantation; the device is reusable but only suitable for single-diameter needles. The device is safe, effective, easy to control, highly practical, simple in production process, low in production cost and remarkable in effect, is a significant improvement on the existing puncture device, is higher in usability and safety and easy to popularize and apply, is more suitable for large-scale production of the pharmaceuticals industry and clinical application of interventional therapy and has good application prospect, the application of the product system in the prior art is expanded, and significant social and economic benefits can be created within short time.

Systems and methods of genomic analysis are presented that provide a framework to determine a tumor's clonality, the number and proportion of all major clones, and the variants that distinguish them. Contemplated systems and methods also allow phasing mutations to parental alleles to so time their emergence within the population of tumor cells, and provide an accurate estimate of the amount of contaminating normal tissue that was present in the tumor biopsy.

The invention discloses a bone tumor biopsy puncture needle. The bone tumor biopsy puncture needle comprises a bone puncture device, a first electric retractor, an electric rotating device and a splayed base, wherein the bone puncture device is connected to the bottom of the first electric retractor; the upper end of the first electric retractor is fixedly connected to the left side of the bottom of the electric rotating device; the electric rotating device is fixedly connected to the bottom of the base; the right side of the bottom of the electric rotating device is fixedly connected with a second electric retractor, and a second high-definition video camera is arranged at the bottom of a connecting rod; the side edge of the base is connected with a monitoring control device. Through the cooperation of the monitoring control device, the electric retractors and the electric rotating device and the unique structure of the puncture and biopsy acquiring device, a biopsy material can be accurately punctured and accurately grasped, the operation success rate is improved, and the pain of patients is reduced.

The invention provides a device for preventing a tumor from spreading after bone tumor biopsy. The device comprises an occlusion bolt and an occlusion screw, a self-tapping external thread is arrangedon the outer wall of the occlusion bolt, a hollow channel is formed in the occlusion bolt, an internal thread is arranged on the inner wall of the hollow channel, and the portion, from the head to the internal thread section, of the occlusion bolt is grooved into a plurality of sections. The outer diameter of the occlusion screw is larger than the inner diameter of the occlusion bolt, the occlusion screw is matched with the internal thread of the occlusion bolt, and the sections on the head of the occlusion bolt are swelled outwards to form fixation. By means of the technology, the contamination of the tumor to the peripheral tissue can be effectively reduced, convenience is brought to micro-invasive treatment of the tumor, and the difficulty that an occlusion device is taken out in a second operation is reduced.

The invention provides a tumor biopsy apparatus, and relates to the technical field of medical apparatus and instruments. By the aid of the tumor biopsy apparatus, the problem of deficiency of tumor biopsy apparatuses suitable for extracting tumor samples during endoscopic surgery can be solved. The tumor biopsy apparatus comprises a biopsy gun and a puncture needle. The biopsy gun comprises a shell with a cavity, a sleeve is mounted in the cavity, an end of the sleeve extends out of the cavity, a first handle is mounted on the sleeve, the sleeve is provided with a puncture needle accommodating cavity along the length direction, the first handle can drive the sleeve to slide along the cavity, and a fixing assembly for fixing the puncture needle is mounted on the shell; a sample injection groove is formed in an end of the puncture needle, and the puncture needle is connected with the shell by the fixing assembly. The tumor biopsy apparatus has the advantage that tumor can be sampled by the aid of the tumor biopsy apparatus during endoscopic surgery.

The invention discloses a minimally invasive channel bone tumor biopsy device, relates to the technical field of medical instruments, and solves the problems that the minimally invasive channel bone tumor biopsy device can only observe in one direction during use, a biopsy position cannot be positioned well, and the detection precision and biopsy quality will be affected. The minimally invasive channel bone tumor biopsy device comprises a mounting arm; the left arc of the mounting arm is slidably connected with a group of rotary mounting seats; the front end face of the left side of the mounting arm is fixedly connected with a set of angle adjusting driving pieces. the left portion and the lower portion of the inner side of the rotary mounting seats are respectively rotationally connected with a set of transmitting assemblies. According to the invention, imaging in two directions is achieved, meanwhile, by adjusting the installation angle of the rotary mounting seats, observation and imaging are conducted on the diseased part at different angles, the bone tumor biopsy position can be better determined, biopsy quality is guaranteed, detection accuracy is improved, unfolding and folding of the receiving assembly and the transmitting assembly can be achieved, and installation and use are convenient.

The invention relates to the technical field of biopsy devices, and concretely relates to a safe bone tumor biopsy device. The device comprises a mounting box, a rectangular fixing column is vertically arranged on the surface of the mounting box, a rectangular sliding groove is formed in one side of the rectangular fixing column, a cylindrical mounting bin is formed in the rectangular fixing column, a second spring is arranged in the cylindrical mounting bin, a fixing block is arranged on the other side of the rectangular fixing column and located on the lower middle portion, a locking block is slidably connected to the side face of the fixing block, and a sampling puncture needle body is movably connected to the side face of the rectangular fixing column. The position needing to be sampled is determined through a positioning table, the sampling puncture needle body is inserted into the body of a patient to sample, a pathological specimen can be obtained through a sampling area, a mixture of polyvinyl alcohol and hydrogel in the embolism storage bin is sprayed out from an instantaneous release ring through a micro water pump to timely block a needle hole, and the sampling punctureneedle is thin to avoid the problem of a large incision.

The invention discloses a medical clinical tumor biopsy sampling device. The sampling device includes a pedestal; each of the four corners at the bottom of the pedestal is provided with a universal wheel having a locking function; the top of the pedestal is connected to the lower end of a first electric push rod; the upper end of the first electric push rod is connected to the bottom of a horizontal plate; a second electric push rod is arranged at the upper part of the horizontal plate; the second electric push rod is connected to a movable plate; the top of the horizontal plate is provided with a disinfection basin; the bottom of the movable plate is provided with a puncture needle; the upper end of the puncture needle is connected to one end of a delivery tube, and the other end of the delivery tube is connected to the liquid inlet of a micro-pump; the liquid outlet of the micro-pump is provided with a collection bag; the micro-pump is arranged on the movable plate; the horizontal plate is provided with a cutting device; and a clamping device is arranged at the bottom of the horizontal plate. Through the cutting device, the needle head of the puncture needle can be cut off and collected, so that virus infection can be avoided; the sampling device can soak aseptic cotton, so that the location where the puncture needle pierces a patient can be disinfected, and the blood of thepatient at the periphery of the puncture needle can be cleaned when the puncture needle is withdrawn; and the sampling device can realize the disinfection of the puncture needle and the delivery tube.

The invention discloses a device for preventing tumor spread after bone tumor biopsy. The device of the invention comprises an operation tube, a connecting tube, a blocking rod and a puncture tube, wherein the puncture tube is in threaded connection below the operation tube; the connecting tube is arranged between a blocking tube and the operation tube; and the puncture tube is used for puncturingtumor tissues, and a biopsy needle extends from the upper end of the blocking rod for sampling during biopsy. Since various parts are tightly connected and tumors can be blocked in all direction, thedevice for preventing tumor spread after bone tumor biopsy has a good anti-spread effect.

The invention provides a biopsy sampler for a digestive tract tumor, belonging to the technical field of medical instruments. The biopsy sampler for the digestive tract tumor comprises a placing plate, wherein the upper surface of the placing plate is provided with a display device and an inflation device, the lower surface of the placing plate is fixedly connected with an outer tube, the outer tube is internally provided with a connecting steel wire and a ventilation tube, the ventilation tube is internally provided with a cable conductor, one end of the connecting steel wire is fixedly connected with a pull ring, and the other end of the connecting steel wire is fixedly connected with a connecting base. Under the action of an inner support frame, an ellipsoidal air bag is greatly deformed at an elastic bag, so a sampling blade drives the fine hair of insoluble dietary fiber to move out of a sampling groove so as to clean dirt on the surface of the tumor, and then a soluble dietary fiber adhesion layer is dissolved, so the fine hair of the insoluble dietary fiber is separated and enters a digestive tract; after the ellipsoidal air bag is deflated, the elastic bag retracts, the sampling blade cuts the tumor and brings the tumor into the elastic bag, and then the tumor can be taken out after inflation.