24 results about "Biospecimen" patented technology

1. Name of the product in this design: Reagent Card. 2. Purpose of this design: This design is used for the analysis and processing of biological samples. 3. The key design feature of this product is its shape. 4. The picture or photo that best illustrates the key design points: Design 1 3D diagram 1. 5. No design highlights, left view of each design omitted; no design highlights, right view of each design omitted; the back of the product is a part that is not easily seen or not easily seen during use, rear view of each design omitted. 6. Design 1 is designated as the basic design.

Disclosed herein are detectable moieties and detectable conjugates comprising one or more detectable moieties. In some embodiments, the disclosed detectable moieties have a narrow wavelength and are suitable for multiplexing. Also disclosed are methods of labeling one or more targets within a biological specimen using any of the detectable conjugates and / or detectable moieties described herein.

A system to store specimen containers in a temperature controlled environment includes at least a first temperature sensor positioned to sense a temperature in a first region of the temperature controlled environment in an interior of the cryogenic storage tank and at least a first level sensor positioned to sense a level of a cryogenic medium within the temperature controlled environment in the interior of the cryogenic storage tank. A method of storing specimen containers in a temperature controlled environment includes monitoring one or more parameters within the temperature controlled environment to prevent exposure of biological samples within the specimen containers to parameters that put the viability of the biological samples at risk.

Compositions, assays, methods, diagnostic methods, kits, and diagnostic kits are disclosed for the specific and differential detection of SARS-COV-2 and / or other viruses from samples, including veterinary samples, clinical samples, food samples, forensic sample, environmental samples (e.g., obtained from soil, garbage, sewage, air, water, food processing and manufacturing surfaces, or likewise), or biological sample obtained from a human or non-human animal.

A device, system, and method for collecting samples for medical testing. The sample collection device includes a collection chamber coupled to a main body. The collection chamber extends from a first collection chamber end to a second collection chamber end. The collection chamber includes an opening adjacent to the second collection chamber end. The opening is configured to receive a first volume of biological sample. A projection extends into the collection chamber. The collection chamber is configured to translate between a first position and a second position relative to the projection, and the translation of the collection chamber from the first position to the second position causes a second volume of biological sample to be released from the collection chamber through the opening.

This application relates to the field of biological sample storage technology, and in particular to a rapidly assembleable low-temperature biological sample storage box and assembly method, comprising an insulated bottom shell, an insulated mounting shell above the insulated bottom shell, and an insulated top cover above the insulated mounting shell. The insulated bottom shell, the insulated mounting shell, and the insulated top cover are interconnected by a connecting body. A placement body is installed inside both the insulated bottom shell and the insulated mounting shell, and storage tubes are installed in uniformly distributed within the placement body. In this application, through the insulated bottom shell, the insulated mounting shell, the insulated top cover, the sponge board, the sealing frame, the placement body, the storage tubes, and the connecting body, the storage tubes containing biological samples can be installed through the placement body. Then, the biological samples are insulated and protected by the insulated bottom shell, the insulated mounting shell, and the insulated top cover, while the placement body cools the air around the storage tubes, making the storage of biological samples inside the storage tubes more stable.

This invention discloses a blood sample detection method and system based on multimodal biological samples, belonging to the field of biological sample detection technology. The method includes: simultaneously collecting blood and urine samples using partitioned test tubes; constructing identification configuration data containing anticoagulation and hemolysis, anti-corrosion and anti-crystallization parameters, region segmentation masks, and a spectral library; constructing an interference benchmark using urine layer spectra; decoupling blood spectral signals through principal component analysis and gradient descent iterative optimization; verifying the interference ratio to be below a first threshold; scanning the blood sample at a preset frame rate to collect component signal distribution data and identify cross-contamination and sample deterioration; if the signal ratio is not up to standard, adaptively updating the decoupling parameters and quantitative operators until the conditions are met, then outputting detection results such as hemoglobin concentration and blood cell count. This invention can effectively eliminate urine interference, improve the accuracy and reliability of blood detection, and is suitable for multimodal biological sample joint detection scenarios.

1. Name of the product in this design: Top-opening programmable cooling device. 2. Purpose of this design: To control the temperature change of biological samples during the freezing process, thereby achieving low-temperature preservation of the samples. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

This invention discloses a new generation of artificial intelligence bioinformatics method for individual geographic tracing, belonging to the field of wildlife DNA geographic tracing technology, including the following steps: S1, obtaining DNA from biological samples; S2, constructing a novel artificial intelligence DNA individual tracing model based on a convolutional neural network module, combined with a CBAM spatial attention module and a multilayer perceptron; S3, training the artificial intelligence DNA individual tracing model using the sample's genotype data and background sampling geographic data as inputs, and optimizing the model parameters using cross-validation; S4, using the artificial intelligence DNA individual tracing model to predict the geographic coordinates of individual DNA from unknown samples. This invention has the ability to integrate data from different species and batches, greatly simplifying the dataset integration process, significantly reducing complexity, and improving repeatability, enabling the prediction of accurate individual geographic locations.

Provided is a picking device (1) comprising: a housing tray (2) in which a housing recess capable of housing a first liquid containing a biological specimen is formed in a tray surface (10); a hollow picking section (3) which is disposed above the housing tray and which acquires the biological specimen through an opening that opens at a distal end part; a first illumination optical system (4) which irradiates the housing tray with a first observation light (OL1) from above through the opening from the inside of the picking section; an observation optical system (6) which is disposed below the housing tray and which observes the first observation light transmitted through the housing tray; and a control unit (7) which controls at least the relative positional relationship between the picking section and the housing tray. The control unit controls the positional relationship of the picking section with respect to the housing recess on the basis of the state of convergence of the first observation light observed by the observation optical system.

The utility model provides profound hypothermia storing and taking equipment for biological sample test tubes, and belongs to the technical field of test tube storing and taking. Comprising a liquid nitrogen tank storage assembly, a cover plate assembly, a test tube box access in-out assembly, a camera assembly, a movable tray assembly and a test tube clamping jaw assembly, and the cover plate assembly, the test tube box access in-out assembly, the camera assembly, the movable tray assembly and the test tube clamping jaw assembly are all installed on the upper surface of the liquid nitrogen tank storage assembly. The liquid nitrogen tank storage assembly, the cover plate assembly, the test tube box access in-out assembly, the camera assembly, the movable tray assembly and the test tube clamping jaw assembly are matched to realize the automation of test tube access, so that the sample storage efficiency can be remarkably improved, and the influence of human factors on the sample quality is reduced; the storage position can be accurately recognized, the whole process is controlled through accurate transmission, it is guaranteed that the test tubes are carried and positioned accurately, the accuracy of storage and taking of the test tubes is improved, and sample confusion and loss are avoided.

It provides a workflow planning manager that coordinates the distribution of biological samples in the analytical system. [Solution] The analysis system comprises one or more diagnostic analyzers and a biological sample transport device. The workflow planning manager is configured to receive multiple requests for analytical tests, determine a proposed run containing at least some of the analytical tests and send it to a candidate diagnostic analyzer, receive predicted run filling information from the candidate diagnostic analyzer, and decide whether to proceed with or reject the proposed run based on the predicted run filling information. If the proposed run is to proceed, the workflow planning manager signals the transport device to transport some or all of the biological samples specified in the proposed run to the candidate diagnostic analyzer; if the proposed run is rejected, it determines an alternative proposed run or sends the proposed run to an alternative candidate diagnostic analyzer.

The present disclosure provides systems and methods which facilitate the prediction of an estimated time in which one or more fluids will optimally be diffused into a biological specimen, e.g., a tissue sample derived from a human subject. In some embodiments, the present disclosure provides systems and methods which facilitate the prediction of an estimated time until a biological specimen will optimally be fixed with one or more fixatives. In other embodiments, the prediction of a future time at which the biological specimen will be optimally fixed is based on time-of-flight data acquired at a particular point in time during the fixation of the biological specimen that has been deemed sufficiently accurate to predict the time at which the biological specimen will be optimally diffused with fixative.

A transport medium is disclosed that can be utilized for both sample collection and molecular diagnostic applications. The transport medium can be utilized with multiple types of biological samples and maintains the stability of nucleic acid present in the biological samples so that one or more nucleic acid assay target(s) present in the biological sample is not substantially degraded during storage and shipping. Also disclosed are kits containing the transport medium, mixtures that include a biological sample disposed in the transport medium, and methods of producing and using the medium.

A vitrification assembly for cryopreserving a biological sample, including a frame, a pair of vertically oriented, horizontally opposed cold plates, a cold plate actuator coupled to the pair of cold plates configured to control a distance between the pair of cold plates, a lift assembly configured to retain and raise and lower the biological sample between the pair of cold plates, a liquid nitrogen reservoir disposed below and around a bottom portion each of the pair of cold plates for cooling the pair of cold plates and the biological sample, and a control system configured to operate the cold plate actuator and monitor a temperature of the pair of cold plates and the biological sample. In some embodiments, the vitrification assembly further includes a heater thermally coupled to the pair of cold plates and operable for warming the pair of cold plates and the biological sample during a rewarming process.

A system and method for developing an application (App) for automated evaluation and analysis of processed biological samples. Such samples are obtained, combined with a nutrient medium, and incubated. The incubated samples are imaged, and the image information is classified according to predetermined criteria. The classified image information is then evaluated according to an App derived from classified historical image information in a database. The classified historical image information is compared with the classified image information to provide guidelines for further processing of the biological sample, with the process-tailored App providing sample process guidelines tailored to the classification assigned to the image information. [Selected Figure] Figure 2

The present invention is in the field of a method for tissue sample preparation, in particular for further investigation of the tissue sample, such as for chemical, physical, or biological investigation thereof. The prepared tissue sample may be used for histological analysis. The tissue sample is typically a biological sample.

This invention relates to the field of medical device auxiliary equipment, specifically to a precise quantitative blood sample collection device and its usage method. The device includes a needle holder body, which is a transparent cylindrical structure. An intelligent control module is threadedly connected to the top surface of the needle holder body. A needle insertion hole is located at the center of the top surface of the intelligent control module. A longitudinal slide rail is provided on the side of the needle holder body, arranged along the axial direction of the needle holder body. A sensing slider is slidably connected to the longitudinal slide rail. Several elastic limiting springs are located inside the needle holder body at its bottom. The needle insertion hole coincides with the axis around which the elastic limiting springs are arranged. This invention, through the linkage of optical sensing and RFID, achieves precise quantitative collection of blood collection tubes of various sizes, automatic tube removal reminders, and real-time data traceability without changing clinical operating habits, thereby improving the standardization level of biobank construction.

Provided herein are a set of primers and probes for detecting rotavirus. The set of primers and probes includes at least one forward primer selected from the group including SEQ ID NOS: 17, 20, 23, 26, 29, 32, 35, 38, 41, 44, 47, 50, 53, 56, 59, 62, 65, 68, 71, 74, 77, 80, 83, 86, 89, 92, 95, 98, 101, 104, 107, 110, 113, 116, 119, 122, 125, 128, 131, 134, 137, 140, 143, 146, 149, 152, 155, 158, 161, 164, 167, 204, 207, 210, and combinations thereof; at least one reverse primer selected from the group including SEQ ID NOS: 18, 21, 24, 27, 30, 33, 36, 39, 42, 45, 48, 51, 54, 57, 60, 63, 66, 69, 72, 75, 78, 81, 84, 87, 90, 93, 96, 99, 102, 105, 108, 111, 114, 117, 120, 123, 126, 129, 132, 135, 138, 141, 144, 147, 150, 153, 156, 159, 162, 165, 168, 205, 208, 211, and combinations thereof; and at least one probe selected from the group including SEQ ID NOS: 19, 22, 25, 28, 31, 34, 37, 40, 43, 46, 49, 52, 55, 58, 61, 64, 67, 70, 73, 76, 79, 82, 85, 88, 91, 94, 97, 100, 103, 106, 109, 112, 115, 118, 121, 124, 127, 130, 133, 136, 139, 142, 145, 148, 151, 154, 157, 160, 163, 166, 169, 206, 209, 212, and combinations thereof. Also provided herein is a method for detecting rotavirus using the set of primers and probes.

The present invention relates to an apparatus for manufacturing a biological sample-based memorial item, the apparatus comprising: an acquisition unit for acquiring a biological sample from a subject; a preservation unit for performing a preservation treatment on the biological sample on the basis of freeze-drying; a sealing unit for sealing the preserved biological sample in a vial; and an encapsulation unit for encapsulating the vial to produce a biological relic capsule, wherein the subject may include at least one of a person or companion animal before or after a funeral.