106 results about "Biospecimen" patented technology

The invention relates to the technical field of infectious disease detection, and discloses a new respiratory infectious disease early warning method, which comprises the following steps: S1, specimen collection and data collection: collecting biological samples of new respiratory infectious disease virus infected individuals and other respiratory infectious disease virus infected individuals, the biological sample comprises a blood sample and a swab sample; meanwhile, basic information of the individuals is collected, wherein the basic information comprises gender, age and respiratory symptom duration; s2, quantitative detection: the biological sample is subjected to quantitative detection by adopting reagents of various respiratory infectious disease viruses, the detection content comprises antigens and antibodies, and the antibodies comprise an I gM antibody, an I gG antibody and an I gA antibody; according to the invention, basic information of individuals and antigen-antibody detection reagent resources of various respiratory infectious disease viruses are deeply integrated, so that the recognition capability of new respiratory infectious disease virus infected individuals is effectively improved.

The disclosed invention provides a cartridge, method and cartridge processing systems for molecular tests that include extracting one or more biological materials from a tissue. The cartridge includes a base having a receptacle inside the base, a lid placed over the receptacle, and a gasket in the base. The base includes a transparent window placed under the receptacle, and the receptacle contains a slide on which the tissue is disposed. A film is disposed on an inner surface of the lid, and the film is suitable to extract the one or more biological materials from the tissue. The gasket surrounds the slide, and the lid creates a sealed chamber around the gasket that encloses the slide, and vacuum suction is applied through a port of the base to press the film against the tissue on the slide.

The invention provides a full-process automatic all-in-one machine for DNA extraction, amplification and sequencing. The full-process automatic all-in-one machine comprises a cabin body, the cabin body is internally provided with a first space, and the first space is internally provided with a biological sample extraction workbench for realizing the whole process of DNA extraction, amplification and sequencing; the top of the cabin is provided with an air inlet duct, the side surface or / and the bottom of the cabin is provided with an air outlet duct, and the air inlet duct and the air outlet duct form negative pressure in the cabin; an amplification area is arranged on the biological sample extraction workbench, a cooling base used for reducing pollutants generated in the amplification process is arranged in the amplification area, and an air suction plate is arranged on the side face of the amplification area; the air suction plate is communicated with the air outlet channel, and pollutants generated in the amplification area are discharged out of the cabin body through the air outlet channel. Pollutants generated in the cabin body can be effectively prevented from facing three positions outside from gaps or cabin door lamps of the cabin body, so that pollution to the surrounding environment is avoided, and the safety of biological experiments is further improved. In addition, the integrated cabin is provided, and the requirement for the operation space of the biological experiment is effectively reduced.

A biological sample collection system and dispensing system is described. The biological sample collection system provides for collection and processing of a biological sample (i.e. bodily fluids collected from nose, throat, or other mucosal membrane of an animal or human). The biological sample collection system includes a sample collector and a collection tube. The sample collector provides a structure for sealing the biological sample in the collection tube for further processing without opening the collection tube, and may provide a structure for collecting the biological sample. When the sample collector and collection tube are removably attached the dispensing system is formed. The dispensing system provides for further processing of the biological sample without opening the collection tube (i.e. without un-securing or removing the plug from the collection tube). The dispensing system further provides dispensing of the processed biological sample without opening the collection tube).

The invention relates to the technical field of cryopreservation equipment, in particular to a control method of a sample access system and the sample access system, and aims to solve the problem that an existing sample access system is low in storage, transfer and access efficiency of biological samples. In order to achieve the purpose, the sample access system comprises a storage device, and the storage device comprises a storage bin and a first interface communicated with the storage bin; the delivery equipment comprises a temporary storage bin, and a second interface and a manual pick-and-place port which are communicated with the temporary storage bin; the transfer equipment can transfer the sample containers to the storage equipment and the delivery equipment through the first interface and the second interface respectively, and can transfer the sample containers between the storage equipment and the delivery equipment; the control method comprises the steps of obtaining a task instruction; selectively executing a warehouse-out task and / or a warehouse-in task according to the task instruction; and a plurality of warehouse-in / warehouse-out tasks can be executed in sequence according to the types and the storage sequence of the warehouse-in / warehouse-out samples.

1. Name of the product in this design: Reagent Card. 2. Purpose of this design: This design is used for the analysis and processing of biological samples. 3. The key design feature of this product is its shape. 4. The picture or photo that best illustrates the key design points: Design 1 3D diagram 1. 5. No design highlights, left view of each design omitted; no design highlights, right view of each design omitted; the back of the product is a part that is not easily seen or not easily seen during use, rear view of each design omitted. 6. Design 1 is designated as the basic design.

1. The name of the design product: storage tank. 2. The use of the design product: the design product is used for storing biological samples. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective view 1.

The invention relates to the technical field of automatic treatment of biological samples, in particular to an automatic space and single-cell multi-omics sample preparation and analysis method and system. In several examples, a continuous flexible sample strip is released from a strip dispensing assembly by a rotation mechanism. A prepared biological sample is fixed on the sample receiving surface of the flexible sample strip to generate a continuous length of prepared sample strip, and space and single cell multiomics data corresponding to the fixed biological sample is generated based on the continuous length of prepared sample strip. In some embodiments, the methods and systems are useful for preparing and analyzing solid phase biological samples, such as OCT embedded frozen tissue blocks or FFPE tissue blocks. In other embodiments, the methods and systems are suitable for preparing and analyzing liquid phase biological samples.

The present application relates to the technical field of biological sample bank equipment management and laboratory safety, in particular to a low-temperature storage equipment shifting system for a biological sample bank and an application method thereof, which comprises a shifting bearing platform, an environment maintaining module, a safety monitoring module and a cooperative control module.The shifting bearing platform is used for bearing and moving the equipment; the environment maintaining module is used for adjusting the internal environment information of the equipment; the safety monitoring module is used for monitoring and obtaining monitoring information, including the posture information, position information and speed information of the shifting bearing platform, the environment information within the preset range of the equipment, the internal environment information of the equipment and the path obstacle information; the cooperative control module is used for moving path planning, controlling the moving range and coordinating the work of the environment maintaining module according to the monitoring information, and performing risk analysis, triggering risk warning and emergency disposal.The present application realizes smooth movement in the shifting process, whole-process low-temperature maintenance, multi-dimensional state monitoring and active risk warning through the integrated and intelligent shifting system, and guarantees the activity of samples and the safety of equipment.

The invention discloses a biological sample microelement digestion and detection method, and relates to the technical field of microelement analysis and testing. According to the method, the biological sample is digested by jointly treating the biological sample through the functional additive and the digestion acid system in combination with optimization of the digestion temperature and the digestion time. After the biological sample is digested, the sample is cooled to the room temperature, deionized water is used for fixing the volume, and after water membrane filtration, the content of 12 trace elements in the sample is determined by adopting inductively coupled plasma mass spectrometry (ICP-MS). The digestion and detection method provided by the invention is simple and convenient to operate, short in digestion time, low in equipment cost, capable of effectively avoiding element volatilization loss, suitable for large-batch sample detection and capable of providing accurate pretreatment and detection technical support for heavy metal exposure evaluation.

The utility model provides a biological sample collecting swab which is characterized in that the biological sample collecting swab comprises a swab head, a connecting rod and a handheld part, and the swab head is located at one end of the connecting rod and used for collecting a biological sample; the handheld part is located at the other end of the connecting rod, the width of the handheld part is equal to or larger than that of the connecting rod, and handheld is facilitated; the surface of the swab head is further provided with color-changeable flocking, after the biological sample is detected, the surface of the swab head changes color, and the effectiveness of sample collection can be judged conveniently.

The utility model relates to the technical field of refrigeration houses, in particular to a biological sample refrigeration house with a stacking mechanism, which comprises a refrigeration house main body, a lofting mechanism is arranged in the refrigeration house main body, the lofting mechanism comprises a buffer compartment, and the buffer compartment is positioned in the refrigeration house main body. A plurality of sealing cabin doors are mechanically connected between the buffer compartment and the refrigeration house main body, a plurality of sample storage mechanisms are arranged in the refrigeration house main body, each sample storage mechanism comprises an ultra-low temperature storage room, and storage goods shelves are fixed to the two sides of the inner walls of the ultra-low temperature storage rooms through bolts; and stacking machine equipment is slidably connected to the interior of the ultralow-temperature storage room. According to the utility model, through the mutual cooperation of internal parts of the lofting mechanism, a worker does not need to enter a refrigeration house, biological samples can be moved to the lower part of stacking machine equipment through the sample platform, and through the mutual cooperation of internal parts of the sample storage mechanism, the biological samples can be taken and stored in a storage shelf.

Disclosed herein are detectable moieties and detectable conjugates comprising one or more detectable moieties. In some embodiments, the disclosed detectable moieties have a narrow wavelength and are suitable for multiplexing. Also disclosed are methods of labeling one or more targets within a biological specimen using any of the detectable conjugates and / or detectable moieties described herein.

A system to store specimen containers in a temperature controlled environment includes at least a first temperature sensor positioned to sense a temperature in a first region of the temperature controlled environment in an interior of the cryogenic storage tank and at least a first level sensor positioned to sense a level of a cryogenic medium within the temperature controlled environment in the interior of the cryogenic storage tank. A method of storing specimen containers in a temperature controlled environment includes monitoring one or more parameters within the temperature controlled environment to prevent exposure of biological samples within the specimen containers to parameters that put the viability of the biological samples at risk.

To provide a cryopreservation device with an integrated tracking device chamber.SOLUTION: Provided is an RFID tag as the tracking device which can be placed in the cryopreservation device as part of the procedure for vitrification of a biological specimen. The cryopreservation device maintains its integrity and keeps the RFID tag securely in the chamber at both ambient conditions when the specimen is collected and under liquid nitrogen where the specimen is stored. The cryopreservation device with an integrated tracking device chamber allows for each individual biological sample to have its own tracking device for monitoring during cryogenic storage.SELECTED DRAWING: Figure 2a

A biological sample collection system is provided, the system comprising: a containment vessel; a sample collection reservoir disposed toward a first end of the containment vessel and comprising a valve disposed in a sample receiving area, the valve comprising: a closed configuration, wherein when the valve is in the closed configuration the biological sample is retained in the sample collection reservoir, and an open configuration, wherein when the valve is in the open configuration the biological sample is released from the sample collection reservoir into a sample storage chamber of the containment vessel; and a cap comprising a pusher; wherein, when the biological sample collection system is closed by engagement of the containment vessel with the cap, the pusher engages with the valve thereby moving the valve from the closed configuration to the open configuration to permit the biological sample to be released from the sample collection reservoir into the containment vessel.

The application discloses a biological sample subpackaging vehicle for scanning code and storing and a method thereof, and belongs to the technical field of biological sample subpackaging. The biological sample subpackaging vehicle for scanning code and storing comprises a mounting box, a conveying belt, a code scanner, a mounting plate, a push block, a pushing drive, a push frame, a back-and-forth drive and a sample frame. The code scanner is fixedly installed on the inner wall of the mounting box. The conveying belt is arranged in the mounting box through the mounting plate. The push block is arranged in the mounting box through the pushing drive. The push frame is arranged on the mounting plate through the back-and-forth drive, and two push frames are arranged. The sample frame is movably arranged on the conveying belt. The code scanner can automatically scan the bar code on the top surface of the sample frame. According to the different bar codes, the sample frame is conveyed into the corresponding storage frame through the conveying belt driven by the stepping motor, and then the sample frame is pushed into the storage frame through the push block driven by the first cylinder for storage.

The embodiment of the present application provides a single-taken multiple liquid nitrogen tank storage and taking equipment, and relates to the field of biological sample bank sample storage and taking. The present application is aimed at improving the problems of easy inactivation, low efficiency and danger of biological samples in the existing frozen tube manual storage and taking process. The present application comprises a storage rack, a liquid nitrogen tank, a tube taking group and a transmission group. The storage rack is fixed in the liquid nitrogen tank, and the storage rack is provided with a plurality of first placing grooves. The tube taking group comprises a moving rack and a plurality of clamping jaws. The moving rack is provided with a plurality of second placing grooves. The transmission group is arranged on the liquid nitrogen tank, and the transmission group is connected with the moving rack. The transmission group is used for driving the moving rack to move, so that the moving rack moves into the storage rack and expands, or moves out of the storage rack and gathers. Through the expansion of the moving rack by moving downward, the tube taking group enters the storage rack, the moving rack expands rapidly in the storage rack, and the tube taking group cooperates with the storage rack to realize the accurate transfer of the frozen tube. The tube taking group does not need manual tube taking, the operation time is short, and the efficiency is greatly improved.

The invention discloses a cytology specimen pretreatment system and method based on machine vision and intelligent decision, and relates to the technical field of biological sample treatment.The cytology specimen pretreatment system comprises an operation platform, and the operation platform is provided with a first oscillation module, a centrifugal module, a visual recognition module and a sample tube operation assembly; automatic uniform mixing and centrifugal operation of sample liquid are achieved, so that early-stage materials meeting the requirements of cytology specimens are obtained, excessive manual intervention treatment is not needed, the labor cost and the infection probability in the operation process of medical staff are reduced, the working efficiency of early-stage treatment of the cytology specimens is improved, the requirement for experience of operators is low, and the operation cost is reduced. In addition, the cytological specimen is completely prepared, the cytological wax block and the thin layer are prepared, and the supernate is reserved, so that the opportunity of grafting the cytological specimen to other detection platforms subsequently is increased, and the value of the cytological specimen in pathological diagnosis is improved.

The utility model discloses a sampler for biological detection, which relates to the technical field of biological detection and comprises a sampler, a sampler base, a first sampling circulating pump, an electronic element, a positioning seat, a controller and a second sampling pump. An operator can start the first sampling circulating pump through the control key, a biological sample is sucked into the first sampling pipe from the sampling pipe under the action of suction force of the first sampling circulating pump, the first sampling circulating pump can control the sampling speed and flow of the sample, and it is ensured that the sample is extracted according to preset requirements; the sampling amount can be adjusted according to different detection requirements, a biological sample extracted by the first sampling circulating pump flows into the sample storage vessel through the first sample outlet pipe, the sample storage vessel is used for storing the collected biological sample, and the material and design of the sample storage vessel possibly have the functions of preventing the sample from deteriorating and leaking so as to ensure the integrity of the sample before detection.

The present application relates to the field of low temperature biological preservation technology, and particularly relates to a low temperature biological sample transportation storage tank, which comprises an inner tank body provided with a vacuum interlayer and a double-layer structure, an inner tank body is internally provided with a placing rack for fixing biological sample storage equipment, and further comprises an outer tank body provided outside the inner tank body and provided with a heat preservation layer between the inner tank body and the outer tank body; a placing pipe is provided on the inner tank body and used for leading to the inside of the inner tank body. A normally closed sealing mechanism is arranged at the bottom of the placing pipe, the opening operation of the mechanism is driven by a gear and a rack, and a cooling mechanism is synchronously driven. When the disadvantageous operation of opening the placing pipe to access the sample occurs, the higher temperature nitrogen gas in the upper part of the gas phase zone can be automatically drawn back into the liquid nitrogen to be cooled and condensed, the temperature of the gas phase zone is effectively reduced, and the thermal shock of the sample exposure is reduced. Meanwhile, the gaseous nitrogen gas is pressed back into the liquid nitrogen, the partial liquefaction of the gaseous nitrogen gas is promoted, and the loss of the liquid nitrogen caused by the opening operation is reduced.

Provided herein are systems, methods, and cryoprotective solutions for reversible cryopreservation of biological specimens, whole organs, and whole organisms. Exemplary methods include loading a cryoprotective agent into the biological specimen, cooling the biological specimen to a cryogenic temperature for preservation, storing the biological specimen at a preservation temperature state to preserve the biological specimen, rewarming the biological specimen by increasing a temperature of the biological specimen above the preservation temperature state, and unloading the cryoprotective agent from the biological specimen. The cooling is performed at a first rate to reduce ice formation, substantially homogeneously to reduce propensity for cracking of the preserved biological specimen, and at a first pressure to prevent or reduce ice expansion within the preserved biological specimen. The rewarming is performed at a second rate to reduce ice formation, substantially homogeneously to reduce propensity for cracking, and at a second pressure to prevent or reduce ice expansion.

Compositions, assays, methods, diagnostic methods, kits, and diagnostic kits are disclosed for the specific and differential detection of SARS-COV-2 and / or other viruses from samples, including veterinary samples, clinical samples, food samples, forensic sample, environmental samples (e.g., obtained from soil, garbage, sewage, air, water, food processing and manufacturing surfaces, or likewise), or biological sample obtained from a human or non-human animal.

Described herein are methods for analyzing biological samples by liquid chromatography-tandem mass spectrometry or direct injection mass spectrometry.

1. The name of the design product: storage device. 2. The use of the design product: the design product is used for the automatic storage operation of biological samples. The biological samples are put into the storage tank on the storage device, or taken out from the storage tank. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best shows the design points: perspective view.