12 results about "Biological Testing" patented technology

Disclosed is a multiplex quantum dot-based quantitative test card, and a preparation method, apparatus, and use method thereof in the technical field of biological testing, the multiplex quantum dot-based quantitative test card including a multiplex card housing and a test strip, where the multiplex card housing is provided with a plurality of reaction slots configured to accommodate the test strip; the multiplex card housing further includes a plurality of sample loading ports and a plurality of observation windows, where the sample loading ports and the observation windows are in one-to-one correspondence with the reaction slots; and the test strip includes a conjugate pad coated with quantum dot-labeled antibodies, where the quantum dot-labeled antibodies serve as chromogenic substances.

The utility model relates to a biological assay device for arthropods, and discloses a device for carrying out biological assay on spider mites on living plant leaves, which comprises a base (1), a telescopic device (2) and a storage platform (3). A fixing hole (11) is formed in the base (1); the telescopic device (2) is connected with the base (1) through a bolt, the telescopic device (2) comprises an outer pipe (22) and an inner pipe (21), and the outer pipe (22) is provided with a fixing bolt used for fixing the relative position of the inner pipe (21); the storage platform (3) is fixedly connected with the upper part of the inner pipe (21); the utility model has the advantages that the leaf is not easy to damage, the system stability is good, the position of the culture dish is adjustable, the whole device is easy to move, the observation is easy, and the like, and can better complete the biological assay test of the tetranychid on the living plant leaf.

The present application belongs to the field of biological testing. Disclosed are a multi-joint test quantum dot quantitative test cassette, a preparation method and device therefor, and a use method therefor. The multi-joint test quantum dot quantitative test cassette comprises a multi-joint-row cassette shell and test strips, wherein a plurality of reaction cavities are provided in the multi-joint-row cassette shell and are used for the placement of the test strips; the multi-joint-row cassette shell further comprises a plurality of sample-adding holes and a plurality of observation windows, the sample-adding holes and the observation windows corresponding to the reaction cavities on a one-to-one basis; and each test strip comprises a binding pad, which is coated with an antibody marked by quantum dots, the antibody marked by the quantum dots serving as a chromogenic substance. The present application provides a multi-joint test quantum dot quantitative test cassette, which uses quantum-dot-marked quantitative testing, a nitrocellulose membrane with a plurality of test lines, and the form of the multi-joint-row cassette shell. Thus, the problems of quantitative testing and multi-joint testing are both solved, and the test efficiency and accuracy are improved; furthermore, the present application achieves the aim of rapidly diagnosing various allergic diseases of a human body that are caused by the inhalation and ingestion of allergens.

The present invention belongs to the field of biological testing, specifically relating to a nucleic acid extraction device and a method for extracting and amplifying target nucleic acids using the device. The device comprises a nucleic acid extraction element, a waste liquid storage chamber, and a reaction chamber. The reaction chamber selectively communicates with the nucleic acid extraction element and the waste liquid storage chamber, and fluid exchange occurs through pressure fluctuations between the waste liquid storage chamber and the reaction chamber. The present invention utilizes an integrated control system that discharges fluid from the reaction chamber into the waste liquid storage chamber under negative pressure, resulting in convenient operation and high efficiency.

The invention belongs to the technical field of chromatographic separation and preparation, and particularly relates to a centrifugal column chromatographic extraction device and method. The device comprises a chromatographic column, an extraction bin, a top cover box, a tubular column and an external connecting assembly, the top cover box and the external connecting assembly are arranged at the top and the bottom of the extraction bin, the tubular column penetrates through the top cover box and is rotationally connected with the top cover box through a bearing assembly, the chromatographic column is contained in the extraction bin and connected with the tubular column, and a sample solution is injected into the chromatographic column through the tubular column. Then pressurizing and injecting a mobile phase, driving the chromatographic column to rotate by the tubular column for chromatographic separation, pressurizing and injecting an extracting solution into the extraction bin, and discharging the separated mobile phase by the extracting solution through an external connecting assembly. While pressurized separation is carried out, high-speed rotating centrifugation of the chromatographic column is utilized, centrifugal force is used as auxiliary drive, mass transfer resistance is reduced, separation efficiency is improved, and a high-efficiency mode and way can be provided for rapid separation and extraction of samples in life science, biological detection and food and drug detection.

The present invention provides a chip-based reagent box for biological testing and a detection method thereof. The detection device includes a flow path guide layer and is stacked with a substrate to form a main body, and a reaction area is provided on a part of a pair of electrodes on the substrate, and a receptor that binds to a detection target is applied to the reaction area. The flow path guide layer has an opening installed at the same position as the reaction area, and the receptor is exposed to the main body at the opening, and a micro flow path is formed between the flow path guide layer and the substrate. The detection method includes steps of dropping, washing, and detection, and the sample liquid is directly dropped into the reaction area from the opening to react with the receptor. After the reaction time, a washing liquid is added to the sample liquid and dropped into the reaction area, which is permeated into the micro flow path by capillary action and discharged, and then the test liquid is dropped into the reaction area to detect the sample. In this method, the sample detection can be completed without applying external force, and the detection efficiency can be improved.

The present invention relates to the field of biological testing. Disclosed are a method for efficient and rapid concentration of lipopolysaccharide (LPS) or lipoarabinomannan (LAM), and an apparatus. The inventor has found by researches that a non-polar macroporous resin within a specific pore size range exhibits adsorption efficiency for LPS or LAM comparable to affinity adsorption, has a large adsorption capacity and a high adsorption rate, and can efficiently elute LPS in combination with a specific eluent to obtain a concentrated LPS sample under test, thereby creating good conditions for the detection of LPS or LAM. By means of the method, efficient concentration of LAM is achieved, providing excellent conditions for the detection of mycobacterium tuberculosis.

A method and system for performing assays for hemoglobin HbA1c, employing a smart phone that interacts with a disposable test strip coated with dry chemistry in physically and chemically segregated reactive zones. In the given regions of the strip, the chemistry interacts with the sample resulting in the conversion of the analyte, such as glycated hemoglobin, into a complexed substrate which can be quantified optically. The phone takes measurements of various parameters during the process of the test reactions, displays relevant instructions and the assay results.

The utility model relates to the technical field of biological inspection instruments, and discloses an independent defrosting biological inspection material cabinet which comprises a box body, a box cover, a cooling mechanism and a ventilation mechanism. The cooling mechanism comprises a hollow base, an inner container, a condenser, a fan and a filter screen. The ventilation mechanism is composed of a sliding frame, a motor, a gear, a baffle and the like. The material inspection cabinet is linked with the single chip microcomputer through the temperature sensor, when the temperature of the inner container is low and the inner wall is frosted, the fan accelerates to operate, external air enters the space between the box body and the inner container through the hollowed-out base, meanwhile, the motor drives the baffle to seal the notch in the bottom of the inner container, the refrigeration effect of the condenser is reduced, and heat-containing air enters the inner container through the filter screen to be defrosted. During cooling, the baffle moves out of the notch, the distance of cold air entering the inner container is shortened, the fan accelerates to enable the cold air to rapidly circulate, efficient cooling is achieved, and storage safety of biological samples is guaranteed.

The invention discloses a plastic foam toxicity evaluation method combining light aging simulation and biological detection, and belongs to the technical field of environmental health and microplastic toxicology. The method comprises the following steps: firstly, carrying out accelerated light aging on plastic foam particles under a simulated sunlight condition, and characterizing physicochemical properties (including surface morphology, particle size distribution and functional group change) of the plastic foam particles; then, carrying out toxicity detection by utilizing a model organism caenorhabditis elegans, and systematically evaluating the biological effect of the light aging EPS through indexes such as egg laying amount, movement behavior and body length. According to the method, the light aging process of the plastic foam in the environment can be truly represented, the incidence relation between the physicochemical change and the toxicity effect can be established, and an effective experimental basis and methodological support are provided for scientific evaluation of the environmental health risk of the plastic foam and product safety supervision.

The application discloses a method for determining a seawater ecological risk evaluation threshold of microplastic particles, and comprises the following steps: (1) preparing pure microplastics, (2) biological testing, and (3) threshold derivation. Through the method, the toxic effect of pure microplastics can be determined instead of the combined toxic effect of microplastics and leaching additives, so that the toxicity of microplastic particles to marine organisms can be more accurately evaluated. In addition, the tested organisms used in the method are all marine organisms, so that the risk of microplastic particles to seawater ecology can be more accurately reflected. The method can also derive the toxicity threshold of microplastic particles to marine organisms.

The present invention relates to a disinfection supply detection method and system, which relates to the field of disinfection detection. The method comprises the following steps: obtaining the categories and quantities of medical devices being disinfected in a disinfection supply room to obtain a distribution of device categories; classifying the device complexity based on the device category distribution to obtain the device complexity; and calculating the number of random inspections of the device disinfection test based on the device complexity to obtain the number of random inspections and randomly sampling the medical devices in the number of random inspections to obtain a set of medical device images; and identifying surface damage on the medical device image set to obtain a set of surface damage parameters. In combination with the device complexity, the method calculates the number of random inspections of the damaged area to obtain the number of random inspections of the damaged area and performs random biological testing on the sampled medical devices to obtain test results. The present invention solves the technical problems of inaccurate, low reliability, and low efficiency in post-disinfection supply detection.