192 results about "Laboratory experiment" patented technology

Systems and methods that provide for automated research into the workings of one or more studied systems include automated research software modules that communicate with domain knowledge bases, research professionals, automated laboratories experiment objects, and data analysis processes, wherein automatically selected experiment objects can be run at an automated laboratory to produce experimental results, and the subsequent data-processing providing automated guidance to a next round of experiment choice and automated research. An Experiment Director rules engine chooses Experiment Objects based on user input through a Query Manager.

The present invention is related to databases and the exchange of scientific information. Specifically the invention discloses a laboratory data management system including a knowledge base that stores characteristics of laboratory reagents, experiment subjects, tissues and cells. The invention also includes an experiment input module that accepts input of parameters of an experiment and data from a knowledge base module. Further, the invention includes a protocol creator connected to the knowledge base module and the experiment input module that creates a laboratory protocol for an experiment based on data supplied from the knowledge base module and the experiment input module. The invention also includes methods to use the described system.

Systems and methods are provided for collecting, preparing, and / or analyzing a biological sample. A sample collection site may be utilized with one or more sample processing device. The sample processing device may be configured to accept a sample from a subject. The sample processing device may perform one or more sample preparation step and / or chemical reaction involving the sample. Data related to the sample may be sent from the device to a laboratory. The laboratory may be a certified laboratory that may generate a report that is transmitted to a health care professional. The health care professional may rely on the report for diagnosing, treating, and / or preventing a disease in the subject.

A robotic laboratory automation workcell preferably includes instruments and equipment that are integrated by using conveyor or track elements and a robotic arm. The automation workcell is controlled by a centralized or main controller or processor using specialized control software to automate the proteomics research process. The automated workcell is capable of performing genetic laboratory experiments from start to finish by moving samples or microplates between the instruments for analysis. A goal of the automated workcell is to perform repetitive procedures in an effort to build and maximize the efficiency of a gene(s) of a targeted organism.

An automated system that conducts, monitors, and validates a cell-line-based biological experiment including one or more treatment compounds or other external stimuli. In one preferred embodiment, the system comprises two principal subsystems, and optionally accessory subsystems. A first principal subsystem is an automated laboratory experiment manager for designing the biological experiment, for constructing an assay plate used to conduct the biological experiment, and for managing one or more of the processes that constitute the biological experiment. A second principal subsystem is an automated data analysis manager for analyzing images, for instance produced by the image production system, to detect image data including biological markers and objects, for analyzing the resulting image data to produce biological data, and for analyzing the biological data to produce biological phenotypes and treatment compound signatures.

Method for evaluating cement integrity in a cased well environment using a logging tool that has a neutron source and one or more neutron or gamma ray detectors. Neutron porosity logs are obtained from the well before (42) and after (41) casing. This log data along with well dimensions and material composition parameters are the input quantities to a multi-parameter database (43) that is constructed by computer modeling or laboratory experiments to relate volume fraction for fluid filled channels in the cement sheath to the input quantities. The channel volume fraction (45) corresponding to the input quantities is identified or interpolated (44) from the multi-parameter database.

The invention discloses a laboratory experiment system for simulating the sliding process of landslide along three-dimensional terrain. The laboratory experiment system for simulating the sliding process of landslide along three-dimensional terrain comprises a control device, a chute device, an observing unit and a linking unit, wherein the observing unit is used for recording and simulating the flooding track of a landslide body; the linking unit is used for enabling the observing unit and the control device to operate synchronously; the chute device comprises a horizontal chute and a plurality of slope chutes which are connected from head to tail; two adjacent slope chutes can be connected rotatably; chute lifting devices for adjusting the heights of the horizontal chute and each slope chute are arranged under the horizontal chute and each slope chute; the control device comprises a control table, a control table lifting device for supporting and adjusting the height of the control table, a driving part arranged on the control table as well as a starting device; the bottom of an actuating part of the starting device is arrange in the slope chutes and is tightly matched with the slope chutes; the driving device drives the actuating part of the starting device to act so as to simulate the flooding of a landslide body; an included angle between each slope chute and the horizontal level and an inclined angle between two adjacent slope chutes can be adjusted randomly, so that the slope path becomes universal, and is wider in applicability.

The invention relates to an experiment-numerical analysis combined determination method for the relative permeability coefficient of unsaturated soil. The method comprises simple experiment tests and numerical analyses, the relative permeability coefficient equation of soil under unsaturated state is obtained via simple laboratory experiments and numerical optimization fitting analyses, therefore, the relative permeability coefficient of the unsaturated soil is obtained by calculation. The method is mainly suitable for cohesive soil with a small permeability coefficient. At the same time, the invention provides a numerical analysis procedure which comprises a basic analysis module and an optimization back analysis module, wherein the basic analysis module simulates the dehydration process of test specimens under the condition of a given boundary; the optimization back analysis module takes a determined dehydration mass-time curve as basic input to confirm two parameters Pr and m describing the changes of the relative permeability coefficient of the unsaturated soil along with saturation via an orthogonal optimization method in the numerical analyses. The method is simple in experiments, convenient to operate, wide in usable ranges and good in accuracy; the determined relative permeability coefficient equation can be directly applied to soil engineering structure analyses.

The invention discloses a device and a method for monitoring coal quality; the device comprises a system control module, a coal-carrying vehicle RFID vehicle number automatic identification device, and a sampling sample-preparing chemical examination device; the sampling sample-preparing chemical examination device is a device for integrated continuous process operations of sampling, sample preparation, and chemical examination. The method comprises the following steps: when a coal-carrying vehicle enters a factory, performing vehicle coal-carrying information input before sampling, performing vehicle-arrival sampling, performing vehicle sampling by a mechanical sampler, allowing residual coal in the mechanical sampler to enter a coal quality on-line rapid monitoring analyzing device, performing coal quality on-line rapid monitoring analysis, and displaying monitoring results. The excellent effects of the invention are that: unqualified coal is thoroughly prevented from entering the factory; qualified coal is stored by stacks based on the quality; the coal is blended by the coal entering the factory; the results of laboratory experiment are monitored; disputes between enterprises and coal suppliers are reduced; the qualified rate of the coal entering the factory is reduced from 75% to 0%.

A novel class of agents has been identified to serve as cell-guard agents and / or target-specific supplements to increase cell quality and yield, as well as select for target cell populations. Laboratory experiments have demonstrated the use of cell-guard agents and / or target-specific supplements in the bioprocessing of cells as well as in selecting out a desired cell population. Several potential additive agents (both natural and synthetic) have been identified during these studies, including Vitamin D3, NAC, resveratrol, salubrinal, AKT, and tunicamycin (among others) that hold promise for application in cell models. In one embodiment, hypothermic stress regimes are utilized. In another embodiment, normothermic conditions are utilized while other stressors are tested in the processing. The methods of maintaining mass cell cultures and / or selecting out particular cell populations for further research and clinical use represents an important step in therapeutic discovery. The cell-guard agents are process-matched and cell-matched to protect and / or select particular cells during laboratory and clinical manipulation. The components modulate cell stress and survival pathways.

The invention discloses a high-temperature high-pressure adsorption tester, which is used for testing isothermal adsorption quantity and desorption quantity of coal bed gas and shale gas under different pressure conditions. The high-temperature high-pressure adsorption tester comprises a gas supercharging device, an adsorption device, a temperature control device, a lifting device and a data acquisition system. A pneumatic switch valve is connected to a helium tank; the outlet end of the pneumatic switch valve is connected with a safety valve, a shuttle valve and a booster pump; the outlet of the booster pump is connected with 2 to 8 pneumatic switching valves in parallel; each pneumatic switching valve is connected with a reference tank and a sample adsorption tank; and the other ends of the reference tank and the sample adsorption tank are connected with a pressure transmitter respectively. An evaporator of a refrigeration system is fixed at the bottom of a thermostatic oil tank; and a perforated clapboard, an electric heating element and a temperature controller are fixed in the thermostatic oil tank. The invention has the advantages that: the high-temperature high-pressure adsorption tester is rational and compact in structure and convenient to move and use, and is particularly suitable for laboratory experiments of the desorption quantity and the adsorption quantity of the coal bed gas and the shale gas.

The invention discloses a submerging jet flow testing box and a testing method. The testing box includes a box body, jet flow water inlets, a vision window, a pressure gauge interface, a relief port, a clamp holder, a feeding device interface, a liquid stream valve port, a drainage port and the like. During the laboratory experiment process, a submerging fluid field environment is improved, and the approximate engineering practical submerging jet flow is simulated; other testing instrument is combined, the submerging jet flow fluid field structure is observed; the potential core of jet under the submerging condition is observed combined with a three dimensional laser particle imaging velocimeter (3DPIV) system; the variation of different jet nozzle jet flow fluid field structures is analyzed, and the internal structures of the jet nozzles are optimized; the accelerating mechanism and distribution condition of grinding material particles during the submerging grinding material jet flow testing are analyzed; and meanwhile, the observation experiment for cutting and flushing material under the submerging condition can be performed. The submerging jet flow testing box and the testing method have the advantages that the structure is simple, the operation is convenient, nozzles can be replaced easily, a plurality of testing functions are provided, and compared with other jet flow testing devices, the submerging jet flow testing box not only can test the jet flow fluid field structure under the submerging condition, but also can be reutilized repeatedly, thereby saving the experimental expense at the same time.

An automated system that conducts, monitors, and validates a cell-line-based biological experiment including one or more treatment compounds or other external stimuli. In one preferred embodiment, the system comprises two principal subsystems, and optionally accessory subsystems. A first principal subsystem is an automated laboratory experiment manager for designing the biological experiment, for constructing an assay plate used to conduct the biological experiment, and for managing one or more of the processes that constitute the biological experiment. A second principal subsystem is an automated data analysis manager for analyzing images, for instance produced by the image production system, to detect image data including biological markers and objects, for analyzing the resulting image data to produce biological data, and for analyzing the biological data to produce biological phenotypes and treatment compound signatures.

A process for making Biolimus A9 comprises reacting sirolimus (or rapamycin) with alkyl benzene sulfonate under the catalyzing of organic base and in the presence of organic solvent to undergo a nucleophilic substitution reaction to obtain the Biolimus A9 with high yield, not only for small-scale laboratory experiment, but also for rendering reproducibility of high yield even after process amplification.

The invention discloses a saline-alkaline tolerant germplasm screening and high-yield cultivating method of barley. Laboratory experiments and outdoor experiments are combined for performing saline-alkaline tolerant germplasm screening; the laboratory experiments include germinating experiment and sand culture physiological experiment in a seedling stage, the outdoor experiments include outdoor saline-alkaline tolerance identification experiment of a salt pond and coastal field identification experiment; the cultivating method comprises the steps of film coverage, fresh water salt pressing and moisture making, and carrying out experiments under different sowing times, fertilizers and densities. The method can comprehensively identify and screen saline-alkaline tolerant characteristics of barley in a barley germination period, in a seedling stage and in an adult-plant stage by use of filter paper, sand, the salt pond and seaside heavy saline-alkali soil, and can stably and comprehensively detect the saline-alkaline tolerance of the barley in a high-efficiency manner, and can formulate the relevant high-yield culture technique for the saline-alkali soil.

The invention discloses a central permeation simulation core for laboratory experiments and a preparation method thereof. The central permeation simulation core comprises the following components in parts by weight: 100 parts of quartz sand of 600-425 micrometers, 100-120 parts of quartz sand of 425-250 micrometers, 300-330 parts of quartz sand of 250-180 micrometers, 280-300 parts of quartz sand of 180-150 micrometers, 120-130 parts of quartz sand of 150-100 micrometers, 50-60 parts of quartz sand of 75-50 micrometers and 10-50 parts of a cementing agent. The preparation method of the central permeation simulation core comprises the following steps of: (1) mixing and uniformly stirring six types of constituted quartz sand with the cementing agent so as to form a core base material; (2) uniformly filling the core base material which is uniformly stirred into a core barrel for a plurality of times; (3) filling saturated and filtered injection water into the core barrel; and (4) testing the permeability of the prepared simulation core by adopting a water phase permeability test method. The core has the advantages of simple preparation method, strong operability and high reliability and repeatability. The core can be widely applied to the laboratory physical simulation experiments of the oil field geological and chemical fields.

The workflow application integrates with a research software application associated with a laboratory instrument to provide a user with step-by-step instructions on how to follow the workflow steps of a laboratory experiment. The instructions are dynamically tailored, according to the nature of the workflow, the samples being experimented upon and / or the operating states of the instrument and / or the research software application. The workflow application significantly reduces the learning curve to operate sophisticated laboratory instruments. In a genetic testing instrument the workflow application can prescribe the need for control samples and can optimize the layout of samples within the instrument's sample receiving plate or fixture.

A remote laboratory gateway enables a plurality of students to access and control a laboratory experiment remotely. Access is provided by an experimentation gateway, which is configured to provide secure access to the experiment via a network-centric, web-enabled interface graphical user interface. Experimental hardware is directly controlled by an experiment controller, which is communicatively coupled to the experimentation gateway and which may be a software application, a standalone computing device, or a virtual machine hosted on the experimentation gateway. The remote laboratory of the present specification may be configured for a software-as-a-service business model.

The invention relates to a method for surface modification and transmission increase of coal reservoirs by using chlorine dioxide. The method sequentially comprises the following steps of: (1) selecting the proportioning concentration of the chlorine dioxide according to a coal step and a laboratory experiment; (2) selecting a ground coalbed methane well or an underground drill hole for hydraulic fracturing reservoir modification; (3) pumping chlorine dioxide with selected concentration by stages in the hydraulic fracturing process, wherein the pumping amount in the prepad fluid stage is not less than 70 percent; (4) closing the well for more than 3 hours, and starting to return discharge of a fracturing fluid; and (5) inspecting effects, wherein main indexes comprise critical desorption pressure, daily gas yield and ultimate recovery ratio of the coalbed methane wells or the pumping amount of the underground drill hole. By the method, the daily gas yield and the recovery rate of a single well can be improved, the underground drilling and extraction capability is improved, the extraction efficiency is improved, and the pumping time is shortened.

The invention discloses a novel radial flow displacement physical model system used for researching edge-bottom water reservoir and oil well production performance and water discharging disciplines. The radial flow displacement physical model system can simulate oil well production performance of stratum with different pore structures and different permeability conditions and the water discharging disciplines to carry out laboratory experiment and research, and provides laboratory research and technical support for solving the problem of on-site oil well water discharging. The radial flow displacement physical model system is composed of an injection system (1), a three-dimensional radial flow physical model (2), an oil-gas-water three-phase metering system (3) and a data collection system (4). According to the radial flow displacement physical model system, conditions of edge-bottom water reservoir temperatures, pressure, stratigraphic dip angles and planar and longitudinal heterogeneity can be simulated, the oil well production performance, the water discharging situations, remaining oil distribution and follow-up water drive, polymer drive and other secondary and tertiary oil recovery technologies can be researched to improve the individual-well producing rate, and the oil recovery rate is further improved.

The invention provides a method for determining remaining oil of a fracture and hole type oil reservoir under the encirclement of a high flow guide channel, and belongs to the field of oil-gas field development. The method includes the steps that first, a particle simulation model and an algorithm of the fracture and hole type oil reservoir are established, a surface tension model of the fracture and hole type oil reservoir is determined, then a numerical method is used for realizing the water-oil displacement process in different fracture and hole combined modes, and thus the remaining oil distribution condition on the microcosmic rock core dimension and the macroscopic oil reservoir dimension under the encirclement of the high flow guide channel can be judged. By the adoption of the method, the simulation effect is consistent with a physical experiment result, laboratory experiments can be replaced, and the remaining oil on the macroscopic oil reservoir dimension and the microcosmic rock core dimension under the encirclement of the high flow guide channel can be determined.

The present invention is related to databases and the exchange of scientific information. Specifically the invention discloses a laboratory data management system including a knowledge base that stores characteristics of laboratory reagents, experiment subjects, tissues and cells. The invention also includes an experiment input module that accepts input of parameters of an experiment and data from a knowledge base module. Further, the invention includes a protocol creator connected to the knowledge base module and the experiment input module that creates a laboratory protocol for an experiment based on data supplied from the knowledge base module and the experiment input module. The invention also includes methods to use the described system.

The invention relates to the field of the monitoring and prewarning of mine power disasters, in particular to an equivalent drilling cuttings weight monitoring device and an equivalent drilling cuttings weight monitoring method. The method comprises the following steps of: determining the relations among bearing pressure distribution, drilling cuttings weight and drilling stress by using a mine pressure theory, on-site actual measurement and laboratory experiment data; determining a key threshold value among the parameters during rock burst; and prewarning before the rock burst. The monitoring device comprises a pressure monitoring device, an instrument and a transmission line, wherein the pressure monitoring device is embedded into an excavation area; and the instrument and the transmission line are used for transmitting monitored data to the ground. A ground monitoring main machine is used for continuously monitoring the change situation of under-well pressure, so that the rock burst can be prewarned according to the key threshold value. In the device and the method, the defects of dangerous drilling cuttings method and incontinuous monitoring in real time are overcome and the safety and effectiveness of rock burst monitoring are improved.

The invention discloses an automatic field data acquisition management system for crops and provides a comprehensive information management system integrating laboratory experiments with large-field experiments in the field of agricultural scientific research. The system comprises a head office information module, a head office experimental module and an experimental base module, wherein the head office information module comprises a WEB service system, an application service system and a center database; the head office experimental module comprises a central client-side system; the experimental base system comprises an experimental base client-side system and a data acquirer-side system; the experimental base module is used for acquiring data of an experimental object of an experimental base through the data acquirer-side system. The whole system is full-digital, and the accuracy and the safety are greatly improved.

The invention relates to the field of fractured reservoir working fluid loss control and reservoir protection in the field of petroleum and natural gas and provides a method for fracture pre-support and leak resisting and plugging while drilling of a fractured reservoir. In order to overcome the defect that leak resisting and plugging materials of the fractured reservoir cannot give considerationboth to plugging a fracture and keeping the flow capacity of the natural fracture, a harmful solid phase detained in the fracture in the leak resisting and plugging process is converted into a usefulsolid phase which supports the fracture and keeps the flow capacity of the natural fracture, so that the purposes of achieving leak resisting and plugging and keeping the flow capacity of the naturalfracture are achieved. By means of laboratory experiments, considering the compression strength and corrosion ratio of the leak plugging material, a high-strength inertia support material type and a soluble filling material type are preferable; considering the plugging pressure bearing capacity and the permeability restoration of the supported fracture, material concentration matching is optimized; in on-site operation, early-period feeding and later-period supplementing of the leak resisting and plugging material are reasonably controlled. In this way, the purpose of give consideration to both plugging the fracture and keeping the flow capacity of the natural fracture is achieved. The new leak resisting and plugging method has important significance in efficient exploitation of fracturedoil and gas reservoir.

The invention relates to a true triaxial fracturing simulation device for simulating proppant placemen and a working method thereof, and belongs to the technical field of oil and gas field development. The device comprises a fracturing fluid stirring tank, a fracturing pump, a proppant stirring tank, a crack extension simulation component, and an integrated control system which are sequentially connected by a main line. The proppant stirring tank has parallel branch lines. A steering switch is arranged between the fracturing pump and the proppant stirring tank to control the connection and disconnection between the main line and the branch lines of the proppant stirring tank; and a metal-threaded shaft with a certain deformation is installed inside a fracturing simulation rock sample. Theindependent proppant adding device and the steering switch are arranged to improve the shape of the shaft and add a fiber material, the sealing strength between the shaft and the rock sample contact surface is improved, sand adding simulation is achieved during a crack initiation / expansion process, the success rate of true triaxial fracturing laboratory experiments is improved, and the true triaxial fracturing simulation device has important guiding significance for studying the proppant migration law and the optimal design of a fracturing construction scheme.

The invention relates to a multifunctional test and experiment platform for a desk research of jet drilling. The multifunctional test and experiment platform for the desk research of the jet drillingcomprises a power module, an experimental condition control module, a test and detection module, a fluid circulation module, and a drilling assembly. The power module comprises a micro-drilling experiment device and a mud pump; the experimental condition control module comprises a center control unit and a confining pressure control unit; the test and detection module comprises a sensing detectionunit, a data acquisition unit, a data processing unit, and a display storage unit; and the fluid circulation module comprises a water faucet, a water tank, a sedimentation and a filtration ditch, a sewage pump, and a simulation wellbore with an opened upper end and a sealed and transparent lower end. According to the multifunctional test and experiment platform for the desk research of the jet drilling, a practical jet drilling process can be simulated in a laboratory, and necessary conditions can be created for carrying out the laboratory experiment of the jet drilling; and automatic controlcan be achieved in an experiment process, the non-visual jet drilling process in the underground can be visualized, and a semi-empirical research is transferred into a scientific and quantified research.

The invention provides a laboratory experiment device and method for solid fluidization exploitation of a gas hydrate. The laboratory experiment device comprises a sea water injection device, an excavation experiment main body module and an experiment data information sampling module. According to the laboratory experiment device and method, a cutter is directly utilized for mechanical crushing of hydrate sediment under the circumstance that the temperature pressure in an exploitation kettle is the same as the actual pressure at the sea bottom, and sea water is injected into the exploitation kettle to ensure that the crushed hydrate particles flow together with the sea water, so that the phase change, the particle diameter distribution and the fluidization effect of the hydrate during mechanical crushing can be simulated, and a theoretical support is provided for solid fluidization exploitation of a non-diagenetic hydrate.

The invention belongs to petroleum exploitation technical field and especially relates to a method for manufacturing an ultrathin and high-definition micro model of a real rock core and a used grinding holder and adhesive in microcosmic simulating oil displacement technology in the field of increase in laboratory experiment recovery efficiency in petroleum industry. A rock core slice is directly bonded between two chromium plate glass layers by the rock core grinding holder and filling adhesive. A manufacturing process is controlled and the micro model of a real rock core is formed integrally. High-definition imaging is achieved on the basis of keeping the original pore structure of the real rock core. The method, the grinding holder and adhesive are mainly used in laboratory microcosmic simulating oil displacement experiments in petroleum industry and are suitable for researching permeability rules of underground fluid, such as petroleum and natural gas or the like, in a porous medium.

The invention includes a method for a client to remotely conduct a laboratory experiment using a remote computer communicating with a host computer in a computer network. The experiment is stimulated by a set of input variable and provides a set of dependent output variables. The method includes the steps of an instructor setting up the experiment at a central location, determining a tolerance band for each input variable of the experiment, and restricting a range of each tolerance band. The instructor enters into the host computer a program to run the experiment. The client remotely access the experiment using the remote computer. The instructor enables the client to conduct the experiment and simultaneously limits the client to the range of each tolerance band.