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45 results about "Laboratory research" patented technology

M88F mutant enzyme for preparing rebaudioside I and application of M88F mutant enzyme

ActiveCN121427867ABacteriaTransferasesPhenylalanineLaboratory research
The invention relates to the technical field of biological catalysis, and discloses an M88F mutant enzyme for preparing rebaudioside I. The enzyme is obtained by the following mutations generated by UGT76G1: M88F: methionine of the 88th amino acid sequence of UGT76G1 is mutated into phenylalanine; and the substrate rebaudioside A (RA) can be efficiently and directionally converted into rebaudioside I (RI) with higher value. In an optimized reaction system, the conversion rate stably reaches 40%, and the catalytic efficiency is improved by more than 5-8 times compared with the common reference enzyme. The enzyme preparation has the characteristics of high catalytic activity, mild reaction conditions, simplicity and convenience in operation and the like, shows good stability and reproducibility in laboratory research and large-scale production, and has a wide industrial application prospect.
Owner:成都圆大生物科技有限公司

Diagnostic antibody suitable for immunohistochemical detection of CD228

The invention relates to a specific antibody aiming at CD228 protein and an antigen binding fragment thereof, which are used for detecting and treating various tumors, such as melanoma, mesothelioma, colorectal cancer and the like. The antibody binding fragment is helpful for diagnosis and treatment of cancers through specific binding with CD228. The invention further comprises antibody drug conjugates (ADCs) which bind a drug to an antibody through a linker, so as to improve the therapeutic effect and reduce the influence on normal cells. Meanwhile, nucleic acids encoding the antibodies or antigen-binding fragments thereof are provided to produce recombinant antibodies or fragments. Besides, the invention also provides a kit which is used for laboratory research, clinical diagnosis and treatment effect monitoring, is beneficial to determining whether tissues or cells express CD228 or not, and provides a new strategy for personalized and precise treatment of cancers.
Owner:SHANDONG BIOANTY BIOLOGICAL TECH CO LTD

GIS insulation structure physical model construction method, system, equipment and medium

The invention relates to the field of high-voltage electrical engineering, in particular to a GIS insulation structure physical model construction method, system and device and a medium, and the method comprises the steps: obtaining first electric field distribution data of a GIS insulation structure under a preset voltage; based on the first electric field distribution data, constructing an equivalent electric field model of the GIS insulation structure; calculating second electric field distribution data of the equivalent electric field model by using finite element electric field simulation; the equivalent electric field model is adjusted, so that the difference between the first electric field distribution data and the second electric field distribution data reaches a preset difference condition, and an optimal equivalent electric field model is obtained; and constructing a physical model of the GIS insulation structure based on the optimal equivalent electric field model. According to the method, the engineering representativeness and accuracy of data obtained by performing experimental researches such as partial discharge by using the physical model are greatly improved, and a solid foundation is laid for reliable conversion of laboratory research results to actual engineering application.
Owner:STATE GRID JIANGSU ELECTRIC POWER CO LTD RESEARCH INSTITUTE +1

High-density homogeneous green anode carbon block dynamic formula and forming parameter optimization method

The invention discloses a high-density homogeneous green anode carbon block dynamic formula and a forming parameter optimization method, belongs to the technical field of electrolytic aluminum carbon, and aims to solve the problems that control indexes in a green anode formula and a manufacturing process are too simple, and the quality of a prebaked anode cannot be well controlled and improved. The method comprises the following steps: analyzing the quality of calcined coke for raw anode carbon block burdening; the method is suitable for dynamic formula technology laboratory research of different raw material conditions; quickly analyzing the quality condition of the calcined coke and establishing a feedback system; analyzing the viscosity of the asphalt; and performing a kneading forming process parameter optimization test. According to the method, multi-factor and all-around technology and process research are integrated, the key technology for producing the high-density homogeneous green anode from related raw materials is broken through, high-density homogenization of the green anode volume density index is achieved, the quality of the green anode is remarkably improved, the problem that the volume density of the green anode is not uniform due to quality fluctuation of calcined coke is solved, and the method is pioneered in the industry and has wide application prospects. And the practical value is extremely high.
Owner:CHALCO GANSU ALUMINUM ELECTRICITY CO LTD

Method and system for evaluating quality of coke into furnace by using industrial CT

The application discloses an evaluation method and system for coke quality entering a furnace by using an industrial CT. The evaluation method comprises the following steps: selecting multiple pieces of coke entering the furnace as samples to obtain coke samples A and B to be measured; scanning the original coke samples A and B to be measured by using the industrial CT to obtain original crack and pore characterization values of the coke samples A and B to be measured; treating the coke samples A and B to be measured after processing by using heat treatment and alkali metal corrosion, and then scanning the coke samples A and B to be measured after processing by using the industrial CT to obtain internal crack and pore characterization values of the coke samples A and B to be measured after heat treatment and alkali metal corrosion treatment; processing the internal crack and pore characterization values of the same positions collected, and evaluating the coke quality entering the furnace according to the processing results. The method solves the limitation of observing the coke crack structure in the steel enterprises, is simple to operate, is accurate in result, is suitable for popularization and application in the steel enterprises and laboratory research, and has a good application prospect.
Owner:UNIV OF SCI & TECH BEIJING +1

A bioreactor for plant cell culture

This invention discloses a bioreactor for plant cell culture, comprising a culture container body, a liquid replenishment system, a sampling unit, a stirring and aeration system, and an exhaust gas treatment device. The culture container is made of high borosilicate glass, with the top sealed by a GL45-PP cap and a four-hole stainless steel plate. Externally, it is connected to the liquid material inlet, sampling unit, aeration system, and exhaust gas treatment device via silicone tubing. Gas is bubbled into the culture system through filters in the sampling unit and aeration system, utilizing bubbles and airflow to achieve stirring and realize suspension culture of plant cells. This invention, through the use of a high borosilicate glass culture container, pressure difference-based liquid replenishment, and a convenient sampling unit, achieves continuous plant cell culture, improves the safety, stability, and efficiency of the culture system, enhances cell culture results and the yield of plant secondary metabolites, and meets the needs of laboratory research and industrial production.
Owner:BEIJING FORESTRY UNIVERSITY

Method for detecting content of bromo-oxime ether

The invention provides a bromo-oxime ether content detection method which is characterized by comprising the following steps: adding a bromo-oxime ether reaction solution into an anhydrous aprotic polar solvent, adding a sodium alkoxide solution for reaction, and purifying to obtain a standard sample of a bromo-oxime ether sodium alkoxide derivative; adding the bromo-oxime ether reaction solution into an anhydrous aprotic polar solvent, and adding a sodium alkoxide solution for reaction to obtain a to-be-detected sample of the bromo-oxime ether sodium alkoxide derivative; and analyzing the standard sample and the sample to be detected by adopting a high performance liquid chromatography external standard method to obtain the content of bromo-oxime ether in the bromo-oxime ether reaction liquid. The method is high in detection accuracy, good in repeatability and suitable for being applied to the scenes of laboratory research and development, factory production and the like.
Owner:JIANGSU FENGSHAN BIOCHEMICAL TECH CO LTD

Preparation method and application of antibacterial coating based on polyvinyl chloride plastic

The invention belongs to the technical field of functional polymer materials and photocatalysis, and particularly relates to a preparation method and application of an antibacterial coating based on polyvinyl chloride plastics. Comprising the following steps: S1, pretreatment; s2, carrying out a reaction; s3, post-processing is carried out; s4, compounding with polyelectrolyte; and S5, preparing the coating. Through a specific catalytic cracking process, the waste PVC is converted into a functional photocatalytic antibacterial coating material, so that resource utilization and functional utilization of the waste chlorine-containing plastic are realized; a catalytic cracking process under a solvent-free condition is adopted, so that the use of an organic solvent is avoided; the coating material has relatively good photochemical stability, and can realize a relatively lasting antibacterial effect; the method has relatively low requirements on equipment, reaction conditions are easy to control, and the method is not only suitable for laboratory research, but also convenient for engineering and industrial amplification. And by combining the processing performance of the obtained coating, the technology has popularization and application potential.
Owner:JILIN UNIVERSITY

A safe, efficient and low-cost cleaning solution for suspended cells and its application

The application discloses a safe, efficient and low-cost cleaning solution for suspended cells and application thereof, which comprises multiple kinds of glucose, amino acid supplements, vitamin supplements, anti-shear protective agents and sodium bicarbonate, is designed for the harvesting and washing process of suspended cells, can effectively remove residual culture medium, cell fragments, metabolic waste and process-related impurities while effectively maintaining cell viability, viable cell density and normal morphology, so as to realize the harvesting target of high-purity, high-activity and low-risk material of suspended cells, and is especially suitable for the production process of high-demand cell products such as cell culture meat. The cleaning solution system can be adapted to the continuous harvesting process of a large-scale bioreactor, can be integrated with automatic harvesting equipment, realizes stable, efficient and repeatable cell collection and washing operation, and meets the full-scene requirements from laboratory research and development to industrial production.
Owner:NANJING JOES FUTURE FOOD TECH CO LTD

A method of regulating bubble size in a high temperature molten salt bubble column

The application discloses a method for regulating bubble size in a high-temperature molten salt bubbling tower, comprising the following steps: according to the diameter range of the target bubble required by the bubbling tower, a single-hole bubbling experimental device is built by selecting a bubble distributor with a corresponding characteristic aperture; according to the component of the molten salt required by the bubbling tower, a database of the relationship between the molar ratio of each chemical component of the molten salt and the physical properties is established; in the single-hole bubbling experimental device, a regulation mode is selected according to the size of the characteristic aperture of the bubble distributor, the adjustable range of the bubble diameter is adjusted to the diameter range of the target bubble required by the bubbling tower; and the obtained regulation mode is applied to the bubbling tower; the application can reveal a comprehensive solution of the synergistic mechanism among multiple parameters, so as to realize accurate and predictable control of the bubble size from microns to millimeters, and solve the technical problems from laboratory research to industrial device amplification.
Owner:SHANDONG UNIV

Kit for detecting intestinal core bacteria by TaqMan real-time fluorescent quantitative PCR (Polymerase Chain Reaction) method

The invention discloses a kit for detecting intestinal core bacteria by a TaqMan real-time fluorescent quantitative PCR (Polymerase Chain Reaction) method, and belongs to the technical field of kits. The kit disclosed by the invention comprises standard positive templates of nine common intestinal core bacteria and nine groups of specific primers and probes which are required in a PCR amplification process and correspond to the standard positive templates. The kit disclosed by the invention is simple, convenient and rapid to operate; the specificity is good and the sensitivity is high; complicated raw information data analysis does not need to be carried out; the intestinal core bacteria can be detected and quantified without high-throughput sequencing, and three bacteria can be detected in one reaction hole, so that the cost is greatly reduced. The kit provided by the invention can be used for rapidly and quantitatively detecting nine intestinal core bacteria including bifidobacterium, lactobacillus, prevotella, bacteroides and the like, can partially replace a high-throughput detection method which is higher in cost and more complicated to operate according to research and diagnosis purposes, and is suitable for being widely popularized in clinical detection and laboratory research.
Owner:大连晶泰医学检验实验室有限公司

Construction method of tumor organoid microenvironment chip model, model and application thereof

The invention discloses a construction method of a tumor organoid microenvironment chip model, the model and application of the model. The construction method comprises the following steps: acquiring a tumor organ and preparing cell precipitate; carrying out enzymolysis and digestion treatment on the cell precipitate, and then adding an extracellular matrix to prepare a tumor organ suspension; the method comprises the following steps: adding a tumor organoid suspension into a micro-fluidic culture carrier, culturing to prepare suspensions of fibroblasts and vascular endothelial cells, respectively adding the two cell suspensions into corresponding hole sites of the micro-fluidic culture carrier, and finally culturing to obtain the tumor organoid microenvironment chip model. The model prepared by the method can more truly simulate the complex tumor microenvironment in vivo, is suitable for drug screening and drug sensitivity detection, is beneficial to improving the accuracy and reliability of research, and accelerates the transformation from laboratory research to clinical application.
Owner:JIANGSU AVATARGET BIOTECHNOLOGY CO LTD +1

A metal melt pouring and casting device

The utility model discloses a kind of metal melt pouring casting devices, belong to metal smelting and casting technical field, comprising: support, support is used to support on ground;Tilting frame, tilting frame both sides are rotatably connected with support by pivot, handle is fixedly connected on tilting frame, for placing crucible in tilting frame;Clamping device, clamping device is set on tilting frame, clamping device is detachably connected with crucible.The utility model can realize single independent casting operation when small and medium-sized crucible casting larger mould, can improve the convenience of operation, safety and work efficiency, reduce the dependence on manpower and reduce production risk;The principle and manufacturing process of the device are simple, suitable for laboratory research and development experiment and factory production use.
Owner:SHANXI HENGDA LIGHT METAL NEW MATERIAL CO LTD

Targeted driving-based KRAS targeted heterocyclic compound synthesis path analysis method

The invention discloses a KRAS targeted heterocyclic compound synthesis path analysis method based on targeted driving, and belongs to the technical field of KRAS targeted heterocyclic compound synthesis. The method comprises the following steps: firstly, establishing a target point-path adaptation relationship between a synthesis system and a synthesis path and generating a path selection behavior set, then constructing a dynamic synthesis label set to record reaction key parameters, then generating a synthesis behavior data matrix and converting the synthesis behavior data matrix into an error feature matrix, and finally, evaluating the binding synthesis system through the error overlapping degree, and generating a consensus path set. According to the method, the problems that a traditional method depends on experience, dynamic tracking is lacked, errors are uncontrollable, and consensus paths are difficult to screen are solved, the objectivity and accuracy of path selection are improved, the synthesis experiment period is shortened, the research and development cost is reduced, and the method is suitable for laboratory research and development and industrial synthesis scenes of KRAS targeted heterocyclic compounds.
Owner:RES INST OF ARTIFICIAL INTELLIGENCE BIOMEDICAL TECH NANJING UNIV

A method for detecting f17 escherichia coli and applications

PendingCN122303454ANucleotidegenomic DNA
This invention discloses a method and application for detecting F17 Escherichia coli. Using the fimbrial virulence gene ctg_04543 or ctg_04549 of F17 E. coli as a target, a fluorescent quantitative probe is designed based on the nucleotide sequence. Using F17 E. coli genomic DNA as a template, the F17 fimbrial gene ctg_04543 or ctg_04549 is detected by fluorescent quantitative PCR. Based on the fitted standard curve, F17 E. coli in the sample can be quantitatively detected. The F17 E. coli detection method provided by this invention is simple, rapid, quantitative, highly sensitive, and highly specific. It can achieve quantitative detection of F17 E. coli within 2-3 hours, meeting the detection needs of various situations such as laboratory research and animal pathogen diagnosis, and has broad application prospects and extremely high market implementation potential.
Owner:YANGZHOU UNIV +3

Anti-pollution magnetic type detection kit

The present invention relates to the technical field of rapid detection, particularly to an anti-pollution magnetic type detection kit, which comprises a box cover and a box body, the box body and the box cover are groove-shaped, the box body and the box cover are matched and are fixed through a magnetic structure, and the grooves are relatively closed; a sample adding hole and an observation window are formed in the box cover in a penetrating manner, an upper turning cover is further arranged on the upper bottom surface of the box cover, and the sample adding hole and the observation window are closed by the upper turning cover; the upper turning cover is arranged on the box cover through the rotating shaft, the rotating shaft is rotationally connected with the box cover, the buckle is arranged at the other end, opposite to the rotating shaft, of the upper turning cover, a clamping groove is formed in the position, opposite to the buckle, of the box cover, and the buckle is detachably arranged in the clamping groove; by means of magnetic attraction design connection, a good tight connection effect is achieved, the service life is long, abrasion or failure is not prone to occurring, and the device is suitable for being used for a long time in laboratory research and other scenes needing frequent opening and closing; the upper turning cover is arranged, so that the sample adding hole and the observation window can be tightly covered before the kit is used, and the abnormal detection result caused by pollution is avoided.
Owner:HENAN UNIVERSITY

Portable movable hyperspectral analysis light source system

The invention discloses a portable movable hyperspectral analysis light source system, and relates to the technical field of spectral analysis equipment, the portable movable hyperspectral analysis light source system comprises a frame body mechanism, a light source box body mechanism and a moving mechanism, through the action of clockwise rotating a grip by 90 degrees, a series of linkage reactions are triggered, the overall height of the device is reduced, and the operation is convenient. By means of the design, an operator can easily and rapidly complete height lowering operation and make preparation for follow-up movement, after the overall height and the gravity center of the device are lowered, the situations of shaking or toppling and the like caused by the too high gravity center in the movement process are effectively reduced, and the portability and deployment flexibility of the device are improved. Meanwhile, multi-light-source cooperation is adopted, switching between an LED (360-780 nm visible light wave band) spectrum and an iodine-tungsten lamp (800-2500 nm near infrared wave band) spectrum is achieved in an integrated mode, the spectrum coverage integrity of the visible near infrared wave band reaches 98% or above, and the requirements for diversification, complexity and stable light sources from laboratory research to field detection are met.
Owner:SHANDONG VOCATIONAL ANIMAL SCI & VETERINARY COLLEGE

A serum-free culture medium for MSC cells and its preparation method

PendingCN122303142Asignificant synergistic proliferative effectHigh proliferative typeHigh activityProliferation rate
This disclosure belongs to the field of cell culture technology, and specifically relates to a serum-free culture medium for MSCs and its preparation method. The culture medium contains a fixed ratio of basic nutrients and six key regulatory factors, namely transferrin, ascorbic acid, human serum albumin, human fibroblast growth factor rhFGF, platelet-derived growth factor PDGF-BB, and transforming growth factor TGF-β1. By optimizing the combination and concentration of these six key regulatory factors, the proliferation rate and activity of MSCs are significantly improved. It also provides four suitable formulations: high proliferation, high activity, balanced, and economical. The culture effect is stable and reproducible, with high safety and a simple process, making it suitable for laboratory research and large-scale clinical-grade MSC culture.
Owner:SHANGHAI EPIZYME BIOMEDICAL TECHNOLOGY CO LTD

Ultrafiltration device for laboratory research

The utility model discloses an ultrafiltration device for laboratory research, and relates to the technical field of cell preparation. The device comprises a heat preservation shell, wherein an ultrafiltration mechanism and a shunting mechanism are arranged on the heat preservation shell; the ultrafiltration mechanism comprises a reverse assembly, a limiting assembly and an ultrafiltration assembly, the reverse assembly comprises a motor fixedly connected to the inner wall of the heat preservation shell, the output end of the motor is fixedly connected with a rotating shaft, the rotating shaft is fixedly connected with a first bevel gear, the heat preservation shell is rotationally connected with a rotating cylinder, and the rotating cylinder is fixedly connected with a second bevel gear. According to the utility model, through the ultrafiltration mechanism, the driving motor drives the two rotating drums to rotate reversely through the first bevel gear, so that the rotating drums rotating reversely drive the inclined ultrafiltration membrane to stir a culture solution, and opposite counter-flow acting forces are formed in the culture solution, so that cells are promoted to quickly and frequently contact with the ultrafiltration membrane; compared with one-way rotation, filtering of the device is accelerated to a certain extent, and the practicability of the device is improved.
Owner:GUANG DONG YIN ZI SHENG MING YI XUE KE JI YOU XIAN GONG SI

Efficient fermentation shaking table system

The invention discloses an efficient fermentation shaking table system, and belongs to the technical field of bioengineering equipment. Comprising a shaking table main body unit, a pH regulation and control unit for detecting and regulating the pH value of a culture solution in real time, an OD real-time detection unit for monitoring the growth of microorganisms in a non-invasive manner, a continuous trace feeding unit for accurately conveying a nutrient solution, and a central control unit for coordinated control. The central control unit adopts a hybrid control algorithm combining fuzzy PID (Proportion Integration Differentiation) and incremental PID to realize rapid, accurate and overshoot-free adjustment of the pH value; and through a mathematical model based on growth dynamics, intelligent calculation and automatic feeding of the material supplementing rate are realized. The system supports multi-station independent parallel control. The system and the method have the beneficial effects that automation and intellectualization of a microorganism culture process are realized, the experiment efficiency, the data precision and the result repeatability are remarkably improved, laboratory research and industrial production are effectively bridged, and the process amplification risk is reduced.
Owner:SHANGHAI ZHICHU INSTR

A multi-flux permanent magnet stirring device and method

ActiveCN116713447BIncrease the speed of magnetic field changeHighly adjustableProcess efficiency improvementControl systemMaterials science
This invention discloses a multi-throughput permanent magnet stirring device and method. The device includes a sleeve, a permanent magnet, a permanent magnet rotation mechanism, an A tray, a B tray, a trolley, an annular track, an A telescopic rod, a B telescopic rod, and a control system. The sleeve is nested and assembled with the permanent magnet. The annular track is supported inside the sleeve by the B telescopic rod. The A tray is supported inside the sleeve by the A telescopic rod. The B tray is mounted on the trolley via the tray rotation mechanism. The trolley is slidably assembled with the annular track. Using the permanent magnet stirring device of this application, multiple melts can be stirred simultaneously, enabling diversified and multi-level permanent magnet stirring experiments. It has a simple structure, is easy to operate and maintain, and can be widely used in the field of permanent magnet stirring of metallurgical melts. It can also be used in experimental research, satisfying the needs of diversified laboratory research on the effects of permanent magnet stirring on melt solidification, microstructure, and properties, laying the foundation for future industrial applications.
Owner:CENT SOUTH UNIV

High and low temperature battery detection all-in-one machine

1. The name of the design product: high and low temperature battery detection all-in-one machine. 2. The use of the design product: for college and research institutes, laboratory research and development, factory quality inspection, safety testing. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective drawing.
Owner:NEWARE TECH LTD

Preparation process for eliminating performance difference of two sides of aluminum alloy matrix MFI zeolite membrane

The invention relates to the technical field of metal anticorrosive coatings, in particular to a preparation process for eliminating performance difference of two sides of an aluminum alloy matrix MFI zeolite membrane, which comprises the following steps: preparing MFI zeolite membrane synthesis mother liquor from sodium hydroxide, deionized water, tetraethoxysilane and tetrapropylammonium hydroxide; carrying out surface treatment on the aluminum alloy matrix; the aluminum alloy matrix is placed in a reaction kettle containing mother liquor, and the aluminum alloy matrix does not make direct contact with the mother liquor initially; putting the reaction kettle into a drying oven for reaction; the reaction kettle is inverted, so that the surface of the aluminum alloy matrix is in uniform contact with the mother liquor and continuously reacts, and finally the MFI zeolite membrane with consistent properties on two sides is formed. The reaction kettle is heated until a uniform temperature field and a uniform fluid field are formed, and then the reaction kettle is inverted, so that the aluminum alloy is in uniform contact with the reaction liquid containing the primary crystal nucleus, the different-plane effect caused by the uneven temperature field, concentration field and convection in the reaction kettle in the in-situ hydrothermal synthesis process is effectively eliminated, and a foundation is laid for the in-situ hydrothermal synthesis process from laboratory research to large-scale industrial application.
Owner:CIVIL AVIATION UNIV OF CHINA

Nanobody specifically binding bovine ifn-gamma and uses thereof

This invention provides a nanobody that specifically binds to bovine IFN-γ. The nanobody has three complementarity-determining regions (CDRs) and four framework regions. The three CDRs are as follows: CDR1: GFTFSTYLM; CDR2: INSGGDST; CDR3: IKDAARQPIDDYGMDY. This invention also provides the application of this nanobody in the detection of bovine IFN-γ. It can be applied to laboratory research, biosensor development, clinical diagnosis, and infection prevention and treatment. The nanobody provided by this invention has many advantages, including small molecular weight, high stability, and low production cost. Compared with traditional IgG antibodies, it has broader application potential and a competitive advantage in the market. Furthermore, the nanobody of this invention is expressed using an E. coli expression system, and the preparation method is simple and stable.
Owner:LANZHOU VETERINARY RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES(LANZHOU BRANCH CENTER OF CHINA ANIMAL HEALTH & EPIDEMIOLOGY CENTER)

A multifunctional visualization device suitable for high-temperature corrosion and phase change reaction systems

The application discloses a multifunctional visual device suitable for high-temperature corrosion and phase change reaction systems, which comprises a reaction kettle, a corrosion-resistant transparent sealing temperature insulation cover, a multi-angle high-definition probe, an intelligent display, a gas detection system, a pressure regulating system, a condensate water system and a metal rod. The device is adapted to high-temperature and strong corrosive environment through corrosion-resistant materials and a double-layer heat insulation structure. The device can capture gas-liquid flow, phase change, bubble behavior and extraction process in real time. In combination with the pressure regulating system, the device can stabilize the pressure in the reaction kettle and ensure the safe operation of the phase change system. The device can be extended to various reaction systems such as molten salt and liquid metal, and can provide high-precision dynamic data for high-temperature corrosion, phase change and multiphase reaction research. The multifunctional visual device has simple structure and small investment, and can be used as a heating device for laboratory research, especially in the field of molten salt pyrolysis research. The device can directly observe the pyrolysis change and bubble behavior under the heating state, and obtain relevant kinetic parameters.
Owner:ZHEJIANG UNIV OF TECH

A synergistic combination for treating chordoma and use thereof

ActiveCN113101288BOrganic active ingredientsAntineoplastic agentsChordomaTranscriptional expression
The application belongs to the field of medicine, and particularly relates to a synergistically treating chordoma combined drug and application thereof. The combined drug is Notch blocker PF03084014 and ELT or Notch blocker PF03084014 and DOX. Research proves that the Notch blocker PF0308401 targets and regulates the transcription expression of a key transcription regulatory factor Brachyury of chordoma, and inhibits tumor cell proliferation; and can obviously improve the drug resistance of chordoma to the chemotherapeutic drugs DOX and ELT. The application can provide an advantageous laboratory research basis and a transformation research direction for a chordoma drug treatment scheme.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Optical measurement platform

1. The name of the design product: optical measurement platform. 2. The use of the design product: for the production process of embossed glass, float glass, photovoltaic cells, optical film, optical plastic and other products, it is necessary to detect and control the quality of optical properties such as diffuse reflection, specular reflection, diffuse transmission, regular transmission, and can also be applied to laboratory research and testing. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.
Owner:CHENGUANG (CHANGZHOU) NEW MATERIAL TECH CO LTD

Microcontroller-based encoder signal generation device and simulation method

The invention discloses an encoder signal generating device based on a microcontroller and a simulation method, and belongs to the technical field of industrial automatic testing. Aiming at the problems that the existing encoder test depends on entity equipment, the universality is poor, the simulation scene is limited and the like, the device comprises a core control unit, a communication interface unit, a signal generation and output unit and an electrical isolation and level conversion unit. The core control unit executes virtual axis model calculation and signal control, the communication interface receives an upper computer configuration instruction, the signal generation unit outputs incremental orthogonal pulses and absolute serial signals, and the isolation conversion unit converts the signals into industrial differential signals. The method comprises the steps of receiving a configuration instruction, calculating the position of a virtual axis, generating a corresponding signal, and isolating, converting and outputting. The system can flexibly simulate signals and fault states of encoders of multiple specifications, is high in universality and real in simulation, is compatible with industrial equipment through interfaces, and is suitable for scenes of laboratory research and development, production line testing and the like.
Owner:CHANGSHA KETUO ELECTRIC CO LTD

Asphalt concrete core sample lossless clamping device

ActiveCN224262840UPrecisely adapted to strength requirementsprevent overloadWithdrawing sample devicesRoad engineeringArchitectural engineering
The utility model provides an asphalt concrete core sample lossless clamping device which comprises a booster pump, a connecting shaft is arranged at the bottom end of the booster pump, the bottom end of the connecting shaft is connected with a core taking box, and handles are arranged at the two ends of the booster pump. Through precise pressure control, a nondestructive clamping structure, standardized adaptation, man-machine interaction optimization and durability design, the clamping stability, safety and detection accuracy of the asphalt concrete core sample are remarkably improved, and the clamping device is suitable for scenes such as road engineering detection and laboratory research and particularly meets the high-precision nondestructive detection requirement.
Owner:HUBEI YICHANG DINGCHENG ENG TECH SERVICE CO LTD

A model verification system and method for catalytic removal of tar naphthalene of biomass for co-combustion

This invention discloses a model verification system and method for catalytic removal of naphthalene from biomass tar during co-firing, relating to the field of coupled co-firing technology in thermal power plants. The system includes a feedstock supply unit, a reaction simulation unit, a product separation and detection unit, a parameter control unit, and a data processing unit. The feedstock supply unit precisely delivers biomass feedstock, catalyst, and carrier gas; the reaction simulation unit employs a three-stage heating structure and a detachable catalytic bed to simulate operating conditions under different reaction temperatures and catalyst types; the product separation and detection unit acquires key data such as tar yield, naphthalene content, and catalyst coking characteristics through multi-stage separation and precise detection; the parameter control unit automatically adjusts and stabilizes experimental parameters; and the data processing unit performs comparative analysis of experimental data and numerical simulation results. This invention also provides a corresponding model verification method, which achieves systematic verification of the catalytic removal model through steps such as setting operating conditions, data acquisition, simulation modeling, and comparative verification. This invention can simulate multi-variable coupled operating conditions, achieve precise multi-dimensional data acquisition and in-depth comparative analysis, significantly improving the accuracy and reliability of model verification, and is suitable for laboratory research and engineering technology verification.
Owner:BAIYANGHE POWER PLANT OF HUANENG SHANDONG POWER GENERATION CO LTD +1