The invention discloses a Q345q-series super-thick guaranteed performance and flaw detection bridge steel plate comprising the following chemical components in percentage by mass: 0.08-0.16 percent of C, 0.20-0.50 percent of Si, 1.15-1.60 percent of Mn, not more than 0.020 percent of P, not more than 0.010 percent of S, not more than 0.12 percent of microalloyed element (V+Nb+Ti+Ni), 0.010-0.050 percent of AlS and the balance of Fe and residual elements; and carbon equivalent is not more than 0.43. The invention also discloses a production method of the steel plate, comprising the steps of rolling, cooling, straightening, cooling in pile and thermal treatment. In the rolling, the cooling and the straightening, the 130 mm super-thick Q345qD(E) steel plate is successfully developed in the production line of a converter, die casting, mill rolling and normalization thermal treatment through carrying out reasonable composition design, die casting, TMCP (Thermal Mechanical Control Process) rolling and thermal treatment; the secondary flaw detection qualification rate reaches 90 percent, the performance initial test qualification rate reaches 100 percent, and the Z-direction performance of the entity of the steel plate can reach Z15 level. The development of the super-thick steel plate satisfies the higher requirements on bridge industry.