867results about "Supporting apparatus" patented technology

A sample holder includes a first member featuring a first retaining mechanism configured to retain a first substrate that includes a sample, a second member featuring a second retaining mechanism configured to retain a second substrate that includes a reagent medium, and an alignment mechanism connected to at least one of the first and second members, and configured to align the first and second members such that the sample contacts at least a portion of the reagent medium when the first and second members are aligned.

The utility model provides a magnetic frame, and relates to the technical field of biology and medical treatment. The magnetic frame comprises a magnetic frame body and a magnetic fixing piece, a placing space is arranged on one side of the magnetic frame body, and one end, away from the magnetic frame body, of the placing space is open; the two ends of the magnetic fixing piece are arranged on the left side and the right side of the opening of the containing space respectively. According to the magnetic frame, an existing magnetic frame structure is thoroughly changed, and one side of the magnetic frame body is provided with the containing space used for containing the magnetic bead incubation structure and the magnetic fixing belt used for fixing the magnetic bead incubation structure in the containing space, so that the magnetic bead incubation structure of a non-centrifugal tube is fixed.

Methods for determining a location of a feature on a spatial array include (a) providing an array of features on a substrate, where a feature of the array includes a barcoded oligonucleotide having, in a 5′ to 3′ direction, a spatial barcode, a cleavage domain, and a constant sequence; (b) hybridizing a priming oligonucleotide to the constant sequence; (c) extending the priming oligonucleotide using the barcoded oligonucleotide as a template; and (d) determining all or a portion of a sequence of the extended priming oligonucleotide corresponding to the spatial barcode, or a complement thereof, and a location of the extended priming oligonucleotide, and using the location of the extended priming oligonucleotide to determine the location of the feature on the spatial array.

An apparatus may include a microfluidic chip including at least one microfluidic channel and a first at least one electrical interconnect. An apparatus may include a circuit board having at least one interface interconnect and a second at least one electrical interconnect electrically coupled with the first at least one electrical interconnect of the microfluidic chip. An apparatus may include a cartridge enclosing the microfluidic chip and the circuit board, the cartridge including at least one opening allowing access to the at least one microfluidic channel on the microfluidic chip and the at least one interface interconnect.

The invention discloses an optical thermostat with comprehensive vibration reduction and low-temperature in-situ displacement functions, which adopts upper and lower opposite vibration absorbers and a large-mass base to realize first-order to second-order inertial vibration absorption, and further realizes thorough decoupling with an optical platform in a suspension type non-contact manner, and the vibration transmissibility can be reduced to be less than 10%. Resonant frequencies of two systems (a sample table system and a cold head system) are designed to achieve vibration decoupling. The technical problems that in the prior art, the high-grade vibration isolation capacity is insufficient, refrigerator noise is easily coupled to a measuring light path, the low-temperature in-situ precision displacement capacity is lacked, and the contradiction between heat isolation, convenience and cost is difficult to balance can be solved. Under the support of a conventional GM refrigerator, the comprehensive requirements of ultralow basic vibration, strong decoupling of a measurement light path, low-temperature in-situ micron-sized displacement, convenient sample replacement and efficient refrigeration / thermal control are met at the same time.

The utility model relates to a full-automatic all-in-one machine for NGS library building hybridization sequencing interpretation, which is used for sample adding and sequencing of a sequencing chip, and comprises a rack, a manipulator, a library preparation instrument and a sequencing device, the sequencing device comprises a gene sequencer, a sample adding clamping mechanism and a turnover mechanism, the library preparation instrument is used for sample adding of the sequencing chip, and the sample adding clamping mechanism is used for sample adding of the sequencing chip. The sample adding and clamping mechanism comprises a clamping tool and a clamping base, the clamping base is provided with a second positioning groove, the clamping tool is placed in the second positioning groove, the clamping tool clamps the sequencing chip, the overturning mechanism overturns the clamping tool to drive the sequencing chip for sample adding to overturn, the manipulator comprises an execution end and a clamping piece, the clamping piece is arranged at the execution end, and the clamping piece is arranged at the execution end. The clamping piece clamps the clamping tool, and the execution end moves among the library preparation instrument, the turnover mechanism and the gene sequencer, so that the sequencing chip is inserted into a preset position of the slot after being subjected to sample adding and turnover. The clamping tool clamps the sequencing chip, so that the sequencing chip is prevented from being overturned and falling off, automatic insertion of the sequencing chip is realized, and the sequencing efficiency is improved.

The invention relates to the field of space irradiation tests, and provides a multi-degree-of-freedom pose adjusting device for a space irradiation test. The device is formed by sequentially connecting a supporting base, a shear type lifting mechanism, a linear translation mechanism and a pitching mechanism, and can realize accurate translation of a test sample in X, Y and Z axis directions and pitching turnover around a horizontal axis in a vacuum environment. The device provided by the invention is compact in structure and high in adjustment precision, is especially suitable for performing multi-dimensional attitude control on a test sample in a vacuum irradiation environment, and remarkably improves the flexibility and stability of sample positioning and attitude adjustment in a space irradiation test; the problems of motion coupling, precision loss, large occupied space and the like existing in a traditional single-shaft or double-shaft mechanism are solved, high-precision multi-degree-of-freedom motion control under the complex vacuum environment is achieved, and the high-precision multi-degree-of-freedom motion control mechanism has the remarkable advantages of being high in structural integration degree, high in adaptability, high in repeated positioning precision and the like.

The invention relates to a modular floor platform and a laboratory installation based thereon for use in automated laboratories. The floor platform has several profile frame modules (1) and several base plates (3) mounted thereon, forming a platform floor for walking on and setting up laboratory equipment. In addition to the floor platform, the laboratory installation includes an industrial robot (6) and a traversing unit (7) for moving the industrial robot (6). A guide slot (4) in the platform floor allows the traversing unit (7) and the industrial robot (6) to be installed separately on either side of the platform floor by connecting the traversing unit (7) and the industrial robot (6) to each other by means of a connecting element (8) that passes through and is guided in the guide slot (4).The floor platform and the laboratory installation based on it are characterized by their modular and space-saving design, leveling capability and stability, protection against contamination, easy assembly, and adaptability to different laboratory spaces.

A system for clinical analysis by an analytical chip with an actuator device which, in turn, includes a computer module integrating all the signals received by the system and transforming them into analytical results, connectable through a connectivity module with a data processing module connected to an external large-scale clinical data system to generate patterns of diagnoses. A fluid drive module for the impulsion of fluids inside the analytical chip. A thermal module distinguishes thermal areas of the analytical chip. An artificial vision module of the processes is inside the analytical chip. An electronic interface communicates the sensors and actuators integrated in the analytical chip and the actuators of the actuator device with the computer module. A power management module to autonomously power the portable system inside an external container that protects all the previous modules of the actuator device and where the analytical chip is inserted.

Methods for determining a location of a feature in a spatial array with features include: (a) providing an array with a first set of one or more features immobilized on a substrate, a first feature of the first set having a first barcoded oligonucleotide with a first spatial barcode and a first constant sequence, and a second set of one or more features immobilized on the substrate, a second feature of the second set having a second barcoded oligonucleotide with a second spatial barcode and a second constant sequence; (b) attaching the first constant sequence to the second constant sequence to generate a nucleic acid product; (c) determining all or a portion of a sequence of the nucleic acid product or a complement thereof; and (d) associating the second barcoded oligonucleotide with the first barcoded oligonucleotide in the nucleic acid product.

A thermopneumatic interface includes one or more pneumatic inlet ports in fluid communication with one or more pneumatic outlet ports and a cooling loop extending through the thermopneumatic interface. The cooling loop is configured to maintain the thermopneumatic interface at a baseline temperature. The one or more pneumatic outlet ports are configured to contact a surface of a microfluidic chip. Each pneumatic inlet port is configured to receive a change in pressure and provide the change in pressure to a corresponding pneumatic outlet port. The thermopneumatic interface is configured to maintain the microfluidic chip at the baseline temperature.

Aspects of this disclosure include cuvettes used in photometric assays. Aspects of this disclosure further include cuvette modules that use the cuvettes for performing photometric assays. Aspects of this disclosure further include systems and methods for performing photometric assays using the cuvettes.

The utility model provides a polar plate lead plaster adhesive strength testing device which comprises a main body frame, a polar plate releasing device is arranged at the upper end of the main body frame and comprises a mounting bottom plate, and an air cylinder connecting plate is fixedly connected to the middle of the upper end of the mounting bottom plate. The side wall of the air cylinder connecting plate is fixedly connected with a pneumatic finger, two clamping jaws of the pneumatic finger are fixedly connected with reset buckle mounting blocks, reset buckles and pin shafts are arranged on the reset buckle mounting blocks, and rotating shafts are rotationally arranged on the two sides of the lower portion of the mounting bottom plate. The side wall of the rotating shaft is fixedly connected with a bearing plate and a rotating shaft limiting block, one end of the rotating shaft limiting block is in lap joint with the edge of the reset buckle, and a tension spring is arranged in the middle of the rotating shaft limiting block. The device is suitable for testing polar plates with different sizes and weights.

The utility model relates to the technical field of micro-fluidic chips, in particular to a micro-fluidic chip clamp which comprises a clamp main body, a pressing plate mounting groove is formed in the clamp main body, a chip mounting groove is formed in the pressing plate mounting groove, an equipment mounting groove is formed in the bottom of the clamp main body, a liquid inlet is formed in the side wall of the clamp main body, and a liquid outlet is formed in the side wall of the clamp main body. A liquid inlet is formed in the clamp main body, the liquid inlet is communicated with the L-shaped flow channel, the L-shaped flow channel is communicated with the chip mounting groove, a liquid outlet is further formed in the clamp main body, the liquid outlet is communicated with the chip mounting groove through the L-shaped flow channel, opening grooves are formed in the tops and the bottoms of the two sides of the clamp main body, and a micro-fluidic chip is mounted in the chip mounting groove. A pressing plate is mounted at the top of the micro-fluidic chip, and various connections between the micro-fluidic chip and a pump, a valve, a pipeline, a converter and the like are quickly realized through the clamp main body. And the view window arranged on the pressing plate can be used for observation. And the clamp main body is provided with the assembling hole, so that the clamp can be clamped on expansion equipment to realize multiple functions.

The utility model discloses a multi-position suction filtration device for a laboratory. Belongs to the technical field of suction filtration. According to the technical key points, the device comprises a box body, the top of the box body is communicated and connected with a plurality of connecting pipe bodies, the top of the box body is fixedly connected with fixed clamping mechanisms in one-to-one correspondence with the connecting pipe bodies, glass sand core funnels are clamped in the fixed clamping mechanisms, and rubber sealing rings are fixedly connected to the positions, close to the top ends, of the inner walls of the connecting pipe bodies; a first control valve is arranged on the connecting pipe body, a protection box is arranged on one side of the box body at intervals, the inlet end of the protection box is connected with the box body through a first suction filtration pipe, and the outlet end of the protection box is connected with a suction filtration pump through a second suction filtration pipe; the problems that an existing suction filtration device can only perform suction filtration on a single sample and cannot perform suction filtration on a plurality of samples, so that more time is wasted, and the suction filtration efficiency is reduced are solved.

A solid-core ring-magnet having one or more cavities is provided. The magnet can have an overall cylindrical shape or a rectangular-prism shape. In either case, a portion of cavity walls of the magnet are ring shaped, causing the magnetic field lines to emanate from the magnet so that the bead formation is in the shape of a ring. A bead separation magnet having a discontinuous or segmented cavity wall is also provided. The segmented cavity wall causes bead formation to form in a segmented or gapped ring to allow for easier manual pipetting. Also provided are systems and kits having the inventive magnets. Methods of purifying a macromolecule using the inventive magnets are also provided.

The PCR plate according to the present invention includes: a body portion having one or more reaction wells; an insertion portion extending from the body portion, inserted into a nucleic acid extraction cartridge, and having an injection port into which a nucleic acid solution is injected; a flow path portion allowing the nucleic acid solution to flow from the injection port to the reaction wells; and a blocking portion attached to the body portion for blocking backflow of the nucleic acid solution from the reaction wells to the flow path portion side.

The utility model discloses a kind of consumable press-fitting devices. Consumable press-fitting device is used to press-fit consumable, and consumable press-fitting device includes adapter base and adapter gland, adapter base is used to support and position consumable, adapter gland is detachably connected with adapter base, and accommodating cavity that can form containing consumable between adapter base and adapter gland, adapter gland includes avoiding hole part. After adapter gland and adapter are disassembled, consumable provided with sealing membrane can be smoothly placed on adapter base, and after adapter gland and adapter base are assembled, avoiding hole part makes part of consumable exposed, and pipette tip can conveniently pass through sealing membrane and enter inside consumable, and adapter gland compresses consumable, so that pipette tip consumable is not taken away, the stability of consumable is good, the continuity of experiment can be guaranteed, and the efficiency of automated pipetting is improved.

A cuvette support groove is a cuboid-shaped cavity with an opening in the upper portion, light-transmitting openings are formed in the light-facing face and the backlight face of the support groove and used for allowing incident light to pass through, small square prisms are arranged at the four inner corners of the support groove, the four small prisms are consistent in size, one right angle of each small prism coincides with the right angle of the support groove, and the other right angle of each small prism coincides with the right angle of the support groove. The height of the small prism is equal to that of the support groove. And the distance between the two small prisms between the bracket groove light-facing surface and the bracket groove backlight surface is matched with the outer diameter between the two colorimetric light surfaces. And the inner diameter between the side surfaces of the two bracket grooves is matched with the outer diameter between the rough surfaces of the two cuvettes. According to the cuvette bracket groove provided by the utility model, the light surface of the cuvette is clamped by the four small prisms, and the rough surface of the cuvette is clamped by the two side surfaces, so that the cuvette is stably and vertically fixed on the bracket groove. Except the part contacted with the small prism, the smooth surface of the cuvette is not contacted and rubbed with the bracket groove in the plugging process, and the smooth surface is not abraded.

The invention discloses an anti-coagulation blood specimen collection oscillation device, and relates to the technical field of blood collection, and the anti-coagulation blood specimen collection oscillation device comprises a base and a main body forming the device; the movable mechanism is assembled at the upper end of the base and is used for uniformly and automatically oscillating the sample in a reciprocating manner; the locking mechanism is assembled at the upper end of the movable mechanism and is used for generating a trigger signal when the sample main body is inserted in place; according to the anti-coagulation blood sample collection oscillation device, stable positioning of a sample in the treatment process can be ensured through the locking mechanism, displacement caused by vibration or external interference is avoided, the accuracy of an experimental result is ensured, meanwhile, downward pressure is applied to help to correct the position of the sample, deviation caused by the shape of the sample or a non-uniform container is further prevented, and the sampling accuracy is improved. And the sample processing stability is improved.

This utility model relates to the field of pipette technology, specifically to a rotary pipette holder, comprising a base, a column, and a locking mechanism. The base has a detachable collection box with an upper opening, and the collection box has a through hole in the middle. The column includes a first column and a second column. The lower end of the first column passes through the through hole and is rotatably connected to the base. The upper ends of the first column and the lower ends of the second column are fixed or separated by the locking mechanism. The upper end of the second column has a support member for holding the pipette. The collection structure of this utility model allows for a clear view of the amount of liquid dripped from the pipette, and the collection structure can be detached from the holder for easy cleaning.

The present disclosure relates to a method of manipulating magnetic beads in a liquid inside a conduit, wherein the method comprises generating a variable magnetic field using at least one magnet or electromagnet to mix the magnetic beads in the liquid; and wherein a biological or chemical species is attached to the surface of the magnetic beads.

The utility model discloses a multifunctional transfer device and a workstation, and relates to the technical field of molecular diagnosis. The multifunctional transfer device comprises a mounting frame, a liquid transfer part and a clamping transfer part. Wherein the liquid transferring component comprises a liquid transferring power assembly movably arranged on the mounting frame, and the liquid transferring component can move in the first linear direction through the liquid transferring power assembly to generate a liquid suction force or a liquid repelling force; the clamping transfer part comprises a plurality of clamping hands and a clamping hand driving motor, and the clamping hands are rotatably arranged on the mounting frame and are in transmission connection with the clamping hand driving motor; the liquid transfer part and the clamping hand driving motor are arranged side by side in the second linear direction perpendicular to the first linear direction; the liquid transfer part is arranged between the at least two clamping hands in a third linear direction perpendicular to the first linear direction. Therefore, the device has the advantages that the overall structure is compact, and the application range is wide.

The invention discloses a sampling assembly, sampling equipment and a sampling reaction device. According to the present invention, the sampling assembly comprises: a sampling plate, the top of which is provided with an accommodating groove, and the accommodating groove is used for placing a sample collection container; a bulge is arranged at the top of the sampling plate outside the accommodating groove, and is positioned in the middle area in the length direction of the sampling plate; a groove for accommodating the sampling plate is formed in the top of the placing plate; when the sampling plate is placed in the placing plate, at least part of the protrusion is located outside the placing plate. And the sample plate can be conveniently, stably and rapidly grabbed, and the grabbing process is more stable.

There is provided a sample container (112) for use inside an optically integrating cavity (110), comprising an enclosing member comprised of fluorocarbon plastic, the enclosing member having diffuse transmittance of at least 80% and the sample container (112) being adapted to contain a solid or liquid sample.

The utility model discloses a liquid suction device suction head connector placing frame which comprises a base, a bearing assembly is assembled on the top of the base, a sterilization cylinder is clamped on the base through the bearing assembly, a suction head connector bearing assembly located on the outer side of the bearing assembly is further assembled on the top of the base, and the assembly has the height and angle adjusting function. The top side clamp is used for fixing a liquid suction device suction head connector inserted into the sterilization cylinder, an LED sterilization lamp prearranged on the top side of the liquid suction device suction head connector is fixedly arranged on the inner side of the sterilization cylinder in a sleeving mode, and an aluminum reflective mirror prearranged on the peripheral side of the liquid suction device suction head connector is further arranged on the inner side of the sterilization cylinder; according to the liquid suction device suction head connector containing frame, through the arrangement of the flushing bottle on the base, the used liquid suction device can be cleaned in a flushing mode through the flushing bottle, meanwhile, through the arrangement of the sterilization cylinder, an LED sterilization lamp in the sterilization cylinder can be used for emitting sterilization ultraviolet rays, and the liquid suction device suction head connector is efficiently sterilized from the peripheral side in cooperation with an aluminum reflector.

A centrifugal microfluidic technique for heat treating emulsion-divided independent reaction volumes (IRVs) within a centrifugal microfluidic chip, and displacing the emulsion into a monolayer presentation chamber (pc) for imaging. A deep treatment chamber (tc) is provided for the heat treatment, a nozzle having a hydrodynamic radius for forming the IRVs is provided for injecting a sample for the IRVs into the tc filled with a dense immiscible medium. The tc is adjacent a heat controlled element for collectively heat treating the IRVs within the tc, where the IRVs form a 3d packing arrangement. The tc is coupled to a presentation chamber (pc) by an opening through which the IRVs can be selectively displaced without collapsing. The pc is adjacent a window transparent to a wavelength for inspecting the pc.

An adapter for use in a sample preparation instrument. The adapter includes a wall extending between a top edge and a bottom edge and between a first end and a second end. The wall at least partially surrounds a central axis. The adapter includes a base extending from the bottom edge of the wall. The base and the wall forming a cavity for receiving a container. The cavity is configured to hold the container at an angle relative to the tray.