3265results about "Supporting apparatus" patented technology

A sample holder includes a first member featuring a first retaining mechanism configured to retain a first substrate that includes a sample, a second member featuring a second retaining mechanism configured to retain a second substrate that includes a reagent medium, and an alignment mechanism connected to at least one of the first and second members, and configured to align the first and second members such that the sample contacts at least a portion of the reagent medium when the first and second members are aligned.

A sample holder includes a first member featuring a first retaining mechanism configured to retain a first substrate that includes a sample, a second member featuring a second retaining mechanism configured to retain a second substrate that includes a reagent medium, and an alignment mechanism connected to at least one of the first and second members, and configured to align the first and second members such that the sample contacts at least a portion of the reagent medium when the first and second members are aligned.

This disclosure provides methods for spatial profiling of biological analytes present in a biological sample. Methods include generating feature arrays using a master / copy format using recessed arrays, and methods for using such arrays. For example spatially-tagged analyte capture analytes can be used in spatial detection in methods to determine the location of analytes (e.g., proteins) in biological samples.

A sample holder includes a first member featuring a first retaining mechanism configured to retain a first substrate that includes a sample, a second member featuring a second retaining mechanism configured to retain a second substrate that includes a reagent medium, and an alignment mechanism connected to at least one of the first and second members, and configured to align the first and second members such that the sample contacts at least a portion of the reagent medium when the first and second members are aligned.

The invention discloses a method for monitoring the corrosion capacity of a circulating salt spray test chamber, and relates to the technical field of aluminum alloys. The method comprises the following steps of test preparation, device configuration and environment debugging, test process management, monitoring and recording, corrosion degree evaluation and report arrangement and summarization. The test box comprises a box body, a positioning mechanism is mounted in the box body, a spraying mechanism is mounted at the top end of the inner wall of the box body, the positioning mechanism is located below the spraying mechanism, a lifting mechanism is mounted on the peripheral wall of the box body, and a collecting mechanism is mounted at the bottom end of the inner wall of the box body; by arranging the positioning mechanism, aluminum alloy materials of different specifications can be positioned, meanwhile, aluminum alloy can be turned over and rotated, then the aluminum alloy can be sprayed more uniformly and comprehensively through the spraying mechanism, so that it is ensured that salt mist uniformly and comprehensively covers the surface of a sample, and the quality of the sample is improved. And the accuracy of test data can be improved.

A nest for the storage of medical device components, including a top surface, a bottom surface, and a plurality of receptacles for the storage of a plurality of medical device components therein. Each of the plurality of receptacles may include a sidewall portion extending downward from the bottom surface of the nest. Additionally, a plurality of ring-shaped protrusions may be provided to extend upward from the top surface of the nest and surround at least some of the plurality of receptacles. The plurality of ring-shaped protrusions may be sized and configured to receive a bottom portion of a corresponding one of the plurality of receptacles when a plurality of nests are vertically stacked relative to one another.

A sample holder includes a first member featuring a first retaining mechanism configured to retain a first substrate that includes a sample, a second member featuring a second retaining mechanism configured to retain a second substrate that includes a reagent medium, and an alignment mechanism connected to at least one of the first and second members, and configured to align the first and second members such that the sample contacts at least a portion of the reagent medium when the first and second members are aligned.

This disclosure provides methods for spatial profiling of biological analytes present in a biological sample. Methods include generating feature arrays using a master / copy format using recessed arrays, and methods for using such arrays. For example spatially-tagged analyte capture analytes can be used in spatial detection in methods to determine the location of analytes (e.g., proteins) in biological samples.

A sample holder includes a first member featuring a first retaining mechanism configured to retain a first substrate that includes a sample, a second member featuring a second retaining mechanism configured to retain a second substrate that includes a reagent medium, and an alignment mechanism connected to at least one of the first and second members, and configured to align the first and second members such that the sample contacts at least a portion of the reagent medium when the first and second members are aligned.

The invention belongs to the field of laboratory automation equipment, and discloses a control method and system of a task execution device for physical and chemical experiment operation, and the method comprises the steps: initializing and calibrating the device; receiving and analyzing an experiment task instruction; collecting object information through a visual sensor; the upper computer generates an execution scheme according to the strategy library; the electric control rotary clamping jaw is driven to complete operation; force and displacement parameters are monitored in real time, and dynamic adjustment actions are fed back through a closed loop; and judging that the operation is completed according to the threshold. The system comprises a visual sensor, a rotary driving body, an electric control rotary clamping jaw and an upper computer. By integrating visual identification and force sense feedback, fine operations such as clamping, taking and placing, bottle cap screwing and the like can be completed in a self-adaptive mode, the efficiency, precision and reliability of laboratory automatic operation are remarkably improved, manual operation errors are reduced, and good application prospects are achieved.

A coupling device has a support groove that, in a state in which the coupling device is attached to a first shaft-shaped section, allows a member having a shaft shape to be inserted therein in a direction crossing the first shaft-shaped section. The coupling device can fix, to the support groove, a second shaft-shaped section of a tool such as a clamp, which is a supported object, by using a second direction fixing screw while the second shaft-shaped section passes through the support groove. The coupling device can perform coupling to the second shaft-shaped section by means of a second coupling section which is formed by using the support groove and the second direction fixing screw.

The present invention relates to the technical field of plastic aging evaluation, and specifically to a plastic aging performance evaluation instrument, comprising a chassis; a take-in and put-out port, which is opened on the side of the chassis; a cover plate, which is arranged on the inner side of the take-in and put-out port; a plurality of solar light panels, which are distributed in a linear array and fixedly installed on the inner top surface of the chassis; and a driving structure, which is arranged on the chassis and is used to drive the plastic parts to rotate. Compared with the prior art, the present application drives the rotating frame by a driving motor to realize the rotation of the rotating frame, thereby driving the clamping frame to revolve. At the same time, due to the meshing of the transmission gear and the fixed gear ring, the clamping frame can also realize self-rotation during the revolution. This combination of revolution and self-rotation ensures that the clamped plastic parts can be turned over in all directions and without dead angles, so that their outer walls can be fully irradiated. This rotation design not only improves the irradiation efficiency, but also ensures the uniformity of irradiation.

The present invention relates to a plate (1) comprising at least two chips (10) designed for receiving a sample to be lysed, each chip (10) featuring a fluidic network comprising fluidic interfaces (11) which includes: - ports, including: - an elution port (23) linked to a lysing chamber, - a sample outlet port (22) configured for collecting a lysed sample - ducts, including an elution duct between the elution port (23) and the sample outlet port (22), for transferring a lysed sample from the lysing chamber; the chips (10) being aligned with an axis (10a) and regularly spaced apart so that the sample outlet port (22) of each chip (10) coincides with the axis (10a), and are spaced apart with a pitch, characterised in that the elution duct is identical for each chip (10) of the plate (1).

Methods for determining a location of a feature in a spatial array with features include: (a) providing an array with a first set of one or more features immobilized on a substrate, a first feature of the first set having a first barcoded oligonucleotide with a first spatial barcode and a first constant sequence, and a second set of one or more features immobilized on the substrate, a second feature of the second set having a second barcoded oligonucleotide with a second spatial barcode and a second constant sequence; (b) attaching the first constant sequence to the second constant sequence to generate a nucleic acid product; (c) determining all or a portion of a sequence of the nucleic acid product or a complement thereof; and (d) associating the second barcoded oligonucleotide with the first barcoded oligonucleotide in the nucleic acid product.

The invention relates to the technical field of chromatographic instruments, in particular to a high performance liquid chromatograph which comprises a chromatographic instrument body, a reagent bottle storage box is fixedly mounted at the upper end of the chromatographic instrument body, a sample injection pipe head is mounted in the chromatographic instrument body, and the upper end of the sample injection pipe head extends into the reagent bottle storage box. A reagent bottle fixing assembly is installed at the bottom of the reagent bottle storage box, a purification assembly is arranged on the side portion of the reagent bottle fixing assembly, and the purification assembly is fixedly installed on the inner side wall of the reagent bottle storage box. Meanwhile, the upper end and the lower end of the reagent bottle are flexibly clamped and fixed, the stability of the reagent bottle in the detection process is guaranteed, meanwhile, a purification structure is matched, air in the storage box can be purified in time, the situation that different reagents are crossed and mixed during detection is avoided, and the accuracy of final atlas data is improved.

The utility model provides a magnetic frame, and relates to the technical field of biology and medical treatment. The magnetic frame comprises a magnetic frame body and a magnetic fixing piece, a placing space is arranged on one side of the magnetic frame body, and one end, away from the magnetic frame body, of the placing space is open; the two ends of the magnetic fixing piece are arranged on the left side and the right side of the opening of the containing space respectively. According to the magnetic frame, an existing magnetic frame structure is thoroughly changed, and one side of the magnetic frame body is provided with the containing space used for containing the magnetic bead incubation structure and the magnetic fixing belt used for fixing the magnetic bead incubation structure in the containing space, so that the magnetic bead incubation structure of a non-centrifugal tube is fixed.

The invention relates to a space experiment sample observation mechanism, a space experiment device and a fluid physics experiment cupboard, the space experiment sample observation mechanism comprises a plug connector, a sample sleeve and a first heating sheet, the first heating sheet is arranged on the sample sleeve, one end of the sample sleeve is fixed on the back side surface of the plug connector, and the other end of the sample sleeve is fixed on the back side surface of the plug connector; a sample clamping part is arranged at the other end of the sample sleeve; the sample clamping part comprises a circular-arc-shaped sample clamping piece with an opening in the upper side, a bottom connecting piece and a cylindrical sample clamping piece, the sample sleeve, the circular-arc-shaped sample clamping piece and the cylindrical sample clamping piece are coaxially arranged, and the sample sleeve, the circular-arc-shaped sample clamping piece, the bottom connecting piece and the cylindrical sample clamping piece are sequentially connected; the bottom of the arc-shaped sample clamping piece is fixedly connected with the bottom of the cylindrical sample clamping piece through a bottom connecting piece, a sample observation interval position is reserved between the arc-shaped sample clamping piece and the cylindrical sample clamping piece, and a sample observation opening position penetrating in the direction perpendicular to the axis of the cylindrical sample clamping piece is formed in the side wall of the cylindrical sample clamping piece.

A packaging for two pipette tip carriers comprising a peripheral side wall with two longitudinal and transverse sides providing a rectangular box with a passage connecting openings on the top and on the bottom of the box surrounded by a top rim vertically spaced apart from a bottom rim. The top rim is configured to support one of the two pipette tip carriers and the bottom rim is configured to support the other one of the two pipette tip carriers. At least one protrusion vertically extends from the top rim and at least one protrusion vertically extends from the bottom rim wherein each protrusion is configured to pass through a complementary passage in the two pipette tip carriers for horizontally positioning the two carriers on the rectangular shaped box with respect to each other.

Disclosed is a modular diagnostic information acquiring device with a base device (1), a microfluidic chip (2), and an optical measurement device. The base device (1) includes a patient body attachment interface, a microfluidic chip receptacle for removably accommodating the microfluidic chip (2) and a pneumatic control device. The microfluidic chip includes a pneumatic microfluidic chip compartment (23), wherein the pneumatic microfluidic chip compartment (is pneumatically coupled with the pneumatic control device and an optical measurement compartment. The optical measurement compartment inlet is fluidically coupled with the pneumatic microfluidic chip compartment. The optical measurement compartment and the optical measurement device are optically coupled, thereby allowing optical measurements inside the optical measurement compartment. The modular diagnostic information acquiring device is configured to autonomously execute a measurement protocol. The measurement protocol including repeatedly executing a measurement cycle. Each measurement cycle includes a respective sampling phase and a subsequent respective measuring phase. In the sampling phase, a whole blood sample is aspirated into the pneumatic microfluidic chip compartment. In the measuring phase, the whole blood sample is forced out of the pneumatic microfluidic chip compartment and an assay, the assay including either the whole blood sample or a component of the whole blood sample, is forced through the optical measurement compartment. A series of optical measurement data is acquired from the assay while passing the optical measurement compartment.

Provided herein are devices and methods of processing a sample that include, in several embodiments, rotating one or more microfluidic chips that are mounted on a support plate using a motor driven rotational chuck. By spinning one or more of the microfluidic chips about a common center of rotation in a controlled manner, high flow rates (and high shear forces) are imparted to the sample in a controlled manner. Each microfluidic chip can be rotated 180° on the support plate so that the sample can be run back-and-forth through the microfluidic devices. Because the support plate can be driven at relatively high RPMs, high flow rates are generated within the microfluidic chips. This increases the shear forces on the sample and also decreases the processing time involved as the sample can quickly pass through the shear-inducing features of the microfluidic chip(s).

The invention discloses an experiment box for raw material medicine azacitidine, and relates to the technical field of experiment equipment, the experiment box comprises a box body and a sealing device, the left side of the box body is fixedly provided with a temperature control device, the left side of the temperature control device is fixedly provided with a button, the button is electrically connected with the temperature control device, and the front side of the box body is provided with a replacement hole. A replacing plate is slidably mounted on the front side of the box body, a sealing plate slidably penetrates through the right side of the box body, the sealing device comprises a limiting hole, a limiting rod, a limiting spring, a U-shaped rod, a T-shaped plate, a stabilizing plate and a net-shaped frame, and after an experimental container containing azacitidine is placed into the box body, the sealing plate is manually pulled to move leftwards to reset and recover sealing of the box body; when the azacitidine is degraded, moisture in air can enter the box body due to loosening of the sealing plate, so that degradation of azacitidine is accelerated, it can be ensured that the sealing plate is always tightly closed through mistaken touch prevention limitation of the T-shaped plate, and therefore the stability of azacitidine is ensured.

The invention relates to the technical field of oil product detection, in particular to a full-automatic condensation point determinator and a determination method.The full-automatic condensation point determinator comprises a base and a test tube, the top of the base is fixedly connected with a mounting base, the surface of the base and the surface of the mounting base are provided with a test bath mechanism and a supporting mechanism, and the test bath mechanism enables a motor to drive a test bath to rotate; the rotation angle of the motor is controlled through a preset program, precise positioning is achieved, the tedious operation of hole-by-hole adjustment of the original structure is avoided, the rotating shaft is locked through mechanical clamping, angle deviation in the testing process is prevented, then manual adjustment is replaced by the motor and the electric push rod, and the test efficiency is improved. The double locking effect is achieved, accidental displacement can be prevented, and precision and efficiency are improved; according to the clamping mechanism, the four arc-shaped clamping plates apply uniform radial pressure through the first springs to clamp the outer wall of the test tube, the inner diameters of the clamping plates are gradually increased from top to bottom, and the clamping mechanism is compatible with test tubes with different outer diameters.

A test cartridge according to one embodiment of the present invention includes a reagent reaction section in which a plurality of chambers containing test reagents are arranged, a dissolution liquid distribution section connected to a vial container containing a dissolution liquid and supplied with the dissolution liquid to distribute the dissolution liquid to each of the chambers, and a container mounting section having a container insertion space into which the vial container is inserted, surrounding the dissolution liquid distribution section, and mounted to the reagent reaction section.

A microplate holder comprises a top shell portion comprising a plurality of holes constructed and arranged to receive a pipette; and a bottom shell portion constructed and arranged to couple to the top shell portion, the top shell portion and the bottom shell portion configured to at least partially enclose a microplate having a plurality of wells vertically aligned with the plurality of holes of the top shell portion, the bottom shell portion having a bottom region that exposes a bottom surface of the microplate to a light generating source that provides backside illumination for a photoactivation process regarding liquid contents of the microplate.

A fluid loading module, a fluid loading system, a fluid loading method, and a gene sequencing device. The fluid loading module is configured to load fluid to a solid-phase slide. The solid-phase slide comprises a plurality of openings. The fluid loading system comprises a manifold block and a valve device. A first flow channel is disposed in the manifold block, and a first fluid inlet, a second fluid inlet, a first flow channel outlet and a plurality of slide interfaces are provided on the manifold block, both the first fluid inlet and the first flow channel outlet being connected to the first flow channel. Each slide interface is provided with a first hole, the first hole of each slide interface being connected to one opening of the solid-phase slide. The valve device comprises a plurality of first valves. Each first valve is connected to the first flow channel and the first hole of one slide interface, such that the first fluid inlet is in communication with a corresponding slide interface by means of one first valve. The second fluid inlet is in communication with another slide interface.

A microfluidic device is configured to sample, meter and collect a metered volume of body fluid for analysis by means of capillary transport. The device comprises: an inlet section, for receiving the body fluid sample, the inlet section comprising an inlet port; a metering section configured to receive body fluid from the inlet section and comprising a metering channel, wherein the metering section is arranged to separate a metered volume of body fluid filled in the metering channel; and an outlet section comprising a cavity between an outlet part of the metering channel and an outlet orifice of the device, a hydrophilic porous bridge element conformable to a shape of the cavity and inserted in the cavity to substantially fill the cavity and the outlet orifice, and a capillary means attached to the outlet section in contact with the hydrophilic porous bridge element.

A microfluidic chip liquid inlet device disclosed by the present invention comprises a bottom plate and supporting legs, a liquid inlet structure is arranged above the bottom plate, the liquid inlet structure comprises a liquid inlet mechanism, a liquid injection mechanism and a feeding mechanism, and the liquid inlet mechanism comprises a first motor, a rotating rod, a mounting plate, a rotating rod and a first bearing plate. The output end of the first motor is connected with the bottom of the rotating rod, the top of the rotating rod is connected with the bottom of the mounting plate, and the bottom of the mounting plate is connected with the top of the rotating rod. According to the invention, micro-fluidic chips with different sizes can be rapidly and conveniently clamped and fixed, and a plurality of micro-fluidic chips can be subjected to liquid feeding work at the same time, so that the problem that the plurality of micro-fluidic chips cannot be rapidly and conveniently used at the same time is solved; and moreover, the problem that the micro-fluidic chips with different sizes cannot be quickly and conveniently clamped and fixed is solved, and the working efficiency of the liquid inlet device is improved.