6 results about "Plate reader" patented technology

The invention relates to an environment-friendly switch vacuum arc-extinguishing chamber contact temperature monitoring method and system based on surface acoustic wave array sensing and inversion, and belongs to the field of electrical monitoring. In order to solve the problem that in the prior art, non-intrusive and high-reliability monitoring of the contact temperature of the vacuum arc-extinguishing chamber is difficult to realize due to vacuum sealing and metal shielding, the technical scheme of the invention is as follows: an acoustic surface wave sensor array comprising three or more sensing nodes is constructed on the outer wall of the vacuum arc-extinguishing chamber, and the longitudinal temperature gradient distribution of the outer wall is captured in a lossless manner. A narrow-band flat-plate reader antenna is adopted to realize array signal parallel transmission with a high signal-to-noise ratio, and the steady-state temperature of an internal contact is accurately inverted through a pre-trained physical information neural network (PINN) model by utilizing multi-source data fusion and array characteristics. According to the method, a non-intrusive monitoring function from external sensing to internal deduction is realized, the problem that the temperature of the contact cannot be measured in a high-voltage closed environment is solved, and a key technical support is provided for safe operation of environment-friendly switch equipment.

The utility model discloses an elisa plate reader convenient to clean, which comprises an elisa plate reader main body, the elisa plate reader main body is provided with a control panel, a sample loading plate is mounted at a sample inlet of the elisa plate reader main body, a limiting plate is hinged to the sample loading plate, a limiting square groove is formed in the limiting plate, an elisa plate is placed in the limiting square groove, and the elisa plate is arranged in the limiting square groove. A cleaning assembly is arranged above the elisa plate and comprises a first module, a second module and a cleaning brush, the cleaning brush is connected to the second module in an up-down sliding mode, the second module is installed at the output end of the first module, the first module is installed on the microplate reader body, and the second module is installed at the output end of the second module. The sample loading plate and the limiting plate are automatically cleaned through the cleaning assembly, the cleaning efficiency is improved, the limiting plate is hinged to the sample loading plate, separate cleaning is facilitated, and cleaning is cleaner.

The present invention generally relates to a solid-state, multi-well plate reader including an emitter assembly having a plurality of emitters and a receptor assembly having a plurality of receptors, where the positions of these assemblies are not fixed relative to each other but are temporarily aligned for measurement by way of two alignment trays.

A ready-to-use assay kit for modular strip-well plates employs detachable strips whose wells contain co-located, mutually reactive reagents kept apart during storage by an in-well sequestration structure that encapsulates at least one reagent. Upon addition of an aqueous sample, buffer, or water, the structure releases (e.g., rupturable capsules / microcapsules or a phase-change encapsulant), enabling in-well mixing to form a reaction mixture that yields a detection signal. The kit is configured to operate without transfer of reagents between wells prior to reading. Optional features include in situ lyophilization with lyoprotectants, controlled residual moisture, and an inert-gas headspace. Calibrator and control strips may be provided. Detection can be by absorbance, fluorescence, or luminescence using a plate reader.

CRISPR diagnostic systems have shown great potential for detecting SARS-CoV-2, but improvements in sensitivity, specificity, and turnaround time are needed. Typically, a gRNA with CRISPR-Cas12a is used to detect the target DNA and activate its collateral activity, which is then used to cleave a reporter probe. Here, we demonstrate that the parallel use of two or three gRNAs accelerates the probe cleavage rate by up to 4.5 times compared to individual gRNAs. This synergistic effect is related to the parallel activation of CRISPR-Cas12a and the individual activity of the gRNAs. This observation led to a system that, using two gRNAs, detected the SARS-CoV-2 RNA gene N at up to 10 viral copies after prior amplification with RT-LAMP.The proof of concept of the system was demonstrated with 100% detection of positive and negative clinical samples in ~25 minutes using the fluorescence plate reader and ~45 minutes for lateral flow test strips.