25 results about "Microtiter plate" patented technology

Disclosed herein is an instrument and associated methods for a fully automated bench-top NULISA platform, comprising an X-Y-Z-gantry, a microtiter plate stage, an incubator, a quantitative PCR module, a decontamination cleaner for microtiter plates, a microtiter plate sealer, a magnetic probe and comb assembly for sample mixing and magnetic bead extraction, a storage unit for reagents and supplies, and a controller.

Disclosed herein is an instrument and associated methods for a fully automated bench-top NULISA platform, comprising an X-Y-Z-gantry, a microtiter plate stage, an incubator, a quantitative PCR module, a decontamination cleaner for microtiter plates, a microtiter plate sealer, a magnetic probe and comb assembly for sample mixing and magnetic bead extraction, a storage unit for reagents and supplies, and a controller.

The invention relates to a system for amplifying nucleic acids, in particular by means of a polymerase chain reaction, comprising a fluid receptacle (1), in particular a microtiter plate or a microchip, and a reaction mixture (2), which contains at least one nucleic acid (2.1) to be amplified, a polymerase enzyme, a buffer medium (2.2), a plurality of excitable nanoparticles (3), preferably nanostars or nanorods, and quantification means, in particular a fluorescent and / or intercalating nucleic acid dye, the reaction mixture (2) being receivable in the fluid receptacle (1). The system further comprises a reaction chamber (4), which has excitation means, the fluid receptacle (1) preferably being introducible into the reaction chamber (4) and the excitation means (5) being designed to excite the nanoparticles (3); the nanoparticles (3) are designed to generate heat in the excited state; and the reaction chamber (4) has a detection device (6), which is designed to excite the quantification means and quantitatively and / or qualitatively detect same, said excitation means being near-infrared radiation emitters (5).

The industrial design sought to be registered is primarily a well plate for laboratory use, covering the front, back, right and left sides and featuring a peripheral ridge structure interrupted by the four corners and the back. 1.1) Front view; 1.2) Back view; 1.3) Right side view; 1.4) Left side view; 1.5) Top view; 1.6) Bottom view; 1.7) Perspective view

The present invention discloses, in one embodiment, a method of using human induced pluripotent stem cells to generate three-dimensional human organ tissue for therapeutic drug toxicity and discovery⋅. In one embodiment, a high throughput microtiter plate is loaded with both wild type and Rett disease 3D spheroids and exposed to a drug library, and activity is measured and analyzed for disease rescue to wild type cell behavior.

The invention relates to a microtiter plate (100) comprising: a first module (1) having at least one first row (16, 17) of wells (2) for receiving a sample; and a second module (20, 30) having a further row of wells (21, 31), wherein at least the first module (1) is integrally formed and is fixed to the second module (20, 30) in some way so as to provide a connection enabling material transfer between each well (2, 21, 31) of the first and second modules (1, 20, 30), and wherein the microtiter plate (100) is designed as a multi-part microtiter plate (100).

Microtiter plate (100), comprising a first component (1) with at least a first row (16, 17) of wells (2) for receiving a sample and a second component (20, 30) with a further row of wells (21, 31), wherein at least the first component (1) is formed in one piece and is connected to the second component (20, 30) by a fixing, forming a connection for the transport of substances between a respective well (2, 21, 31) of the first and the second component (1, 20, 30), and wherein the microtiter plate (100) is formed as a multi-part microtiter plate (100).

The invention relates to a clamp for pressing a rectangular lid onto an upper face of a rectangular microtiter plate having two parallel longitudinal sides and two parallel transverse sides and a lower face. The invention further relates to a clamp module for storing, positioning, fastening and removing such a clamp. In order to provide, for a lid of a microtiter plate, a clamping system that is not bound to a base plate of a shaking device and is suitable for use in an automated laboratory environment but can also be manually operated if necessary, a clamp is proposed which is effective directly on the unit consisting of the microtiter plate and the lid thereon and can be handled in an automated laboratory environment by means of a clamp module.

Modular organ-on-chip system comprising: - a platform with external dimensions according to a microtiter plate standard, - a plurality of modular cell culture components for holding biological tissues, - wherein the platform and / or modules are manufactured by 3D printing from biocompatible material and can be fluidically connected to each other.

The present disclosure provides devices and methods for a microwell plate cover configured to cover a microwell assay plate. The microwell plate cover includes a cover panel surrounded by a cover frame. A sidewall extends downwardly from the cover frame. The microwell plate cover includes various features for enhancing performance, including features for enhancing stickiness, reducing warpage, reducing sample contamination, reducing wear, reducing sample evaporation, facilitating robotic handling, and providing other benefits.

The utility model relates to a test carrier clamping device and oscillation equipment, the test carrier clamping device comprises a top cover, clamping jaw assemblies and a transmission assembly, at least one group of obliquely opposite corners of the top cover are respectively provided with one clamping jaw assembly, and at least one of the two clamping jaw assemblies located on the group of obliquely opposite corners can move relative to the top cover; the transmission assembly is rotationally connected to the top cover, a driving sliding groove is formed in the transmission assembly, and one end of the clamping jaw assembly is arranged in the driving sliding groove in a sliding mode; wherein the transmission assembly is operably rotated, and one end, arranged in the driving chute, of the clamping jaw assembly can move relative to the driving chute, so that the clamping jaw assembly is pushed to move relative to the top cover, and the test carrier is clamped. Through the structure, the microtiter plate is more convenient to clamp and disassemble, so that the working efficiency is favorably improved.

The present invention relates to a reaction vessel, in particular PCR plate or microtiter plate with at least one cavity for holding sample liquid and a support section radially surrounding the cavity for supporting a covering device which seals the cavity in a fluid-tight manner. The reaction vessel comprises a lifting mechanism which is configured to bring the covering device from a sealing position, in which the covering device rests against the support section, into a removal position, in which the covering device is spaced apart from the support section.

The present disclosure is directed to end-effectors facilitating the interface between robotic systems and a wide variety of interfacing surfaces, e.g., standard microtiter plates and sample preparation workflow instruments, as well robotic systems comprising such end-effectors and methods of using such end-effectors and systems comprising such end-effectors. In certain embodiments, the end-effectors comprise a first gripper finger and a second gripper finger where the fingers are configured to be selectively separable from each other, each figure further comprises an extended member having an attachment end and a contact section opposite the attachment end, and the first gripper finger further comprises a rocker assembly comprising a rocker member facilitating the pivoting and gripping of the gripper fingers.

The industrial design sought to be registered is a laboratory well plate, covering the front, back, right and left sides and characterized by a peripheral ridge structure interrupted by the four corners and the back. 1.1) Front view; 1.2) Back view; 1.3) Right side view; 1.4) Left side view; 1.5) Top view; 1.6) Bottom view; 1.7) Perspective view

A system for analyzing the biofilm inhibition efficacy of the plant rhizome extract, consisting of: a) a plant material collection unit configured to collect Hedychium forrestii var. forrestii rhizomes; b) an extraction unit configured to produce bioactive fractions from the rhizomes by ethanol extraction and solvent-solvent fractionation; c) a biofilm inhibition analysis unit configured to evaluate the effectiveness of biofilm inhibition using microtiter plate assay instruments; d) a microscopy unit for the analysis of biofilm morphology, consisting of a fluorescence microscope with EtBr / AO staining capability and a scanning electron microscope; e) A unit for analyzing amylolytic activity, configured to determine amylolytic properties using spectrophotometric instruments and DNA reagent; and f) a kinetic analysis unit for evaluating Michaelis-Menten kinetic parameters.

The invention discloses an instrument for a full-automatic table type NULISA platform and a related method. The instrument comprises an X-Y-Z portal frame, a microtiter plate objective table, an incubator, a quantitative qPCR module, a microtiter plate decontamination cleaner, a microtiter plate sealing device, a magnetic probe, a comb-shaped assembly, a reagent and consumable storage unit and a controller, wherein the magnetic probe and the comb-shaped assembly are used for sample mixing and magnetic bead extraction.

The invention relates to an examination device 10 for examining samples 4 in cavities 3 of a microtiter plate 2, as well as a system 1 and a method for the automated examination of these samples 4. The examination device 10 has a space 14 in which a drawer 11 is guided. The drawer 11 can be displaced out of the space 14 in an x-direction 40 by means of a first motor 15a. The drawer has a front wall 13 and a receptacle 12, the receptacle 12 being shaped to receive a standardized microtiter plate 2 in the drawer 11 without play. Adjacent to the space 14, the examination device 10 has a matrix 17 of at least ninety-six measuring devices 16, which are arranged to examine the samples 4 in the cavities 3 of the microtiter plate 2 arranged in the drawer 11. The at least ninety-six measuring devices 16 each have a detector 19.The examination device 10 further comprises a second motor 15b, which is configured to move the drawer 11 and / or the receptacle 12 in a y-direction 41 in order to displace the microtiter plate 2 relative to the measuring devices 16 transversely to the x-direction 40.

A microtiter plate assembly is disclosed that includes a base having a plurality of wells, a lid having a lid and a plurality of projections corresponding to the plurality of wells, a magnetic plate adapter including at least one magnet, and a force distribution plate that includes, or is coated with a magnetic or paramagnetic material. The magnetic plate adapter and the force distribution plate provide an amount of force necessary to reduce warping of large microtiter plate assays without increasing the footprint of the microtiter plate.

An implement for eliminating headspace in the testing space(s) (T9 or MPWell) of a test tube (T) or microtiter plate (MP), and methods of using such implements to measure oxygen concentration in a test sample. The implement projects into a test chamber (T9 or MPWell) to displace a portion of a fluid sample within the test chamber (T9 or MPWell) and has longitudinally extending grooves (109 and 229) through which the displaced fluidic content can be discharged from the test chamber (T9 or MPWell).

The invention relates to a clamp for pressing a rectangular lid onto the top surface of a rectangular microtiter plate having two parallel longitudinal sides, two parallel transverse sides, and a bottom surface. The invention also relates to a clamp module for storing, positioning, attaching, and removing such a clamp. To create a clamping system for a microtiter plate lid that is not tied to the base plate of a shaking device, and is suitable for use in an automated laboratory environment but can also be operated manually if necessary, a clamp is proposed that acts directly on the unit consisting of the microtiter plate and the attached lid and can be handled in an automated laboratory environment using a clamping module. Its suitability for use in an automated laboratory environment results from the clamp's design, which incorporates a threaded drive for the clamping element that secures the lid.

An appliance for eliminating headspace in one or more test spaces (T9 or MP wells) of a test tube (T) or microtiter plate (MP) and a method of measuring oxygen concentration in a test sample using such an appliance. The appliance protrudes into a test chamber (T9 or MP hole) to displace a portion of a fluid sample within the test chamber (T9 or MP hole), and has longitudinally extending slots (109 and 229) through which the displaced fluid content can be expelled from the test chamber (T9 or MP hole).

A cell retention apparatus with convective flow is provided. In another aspect, a microplate-based array of microfluidic wells has a heater or cooler which generates controllable temperature gradients within and / or between the wells, such as in an injection molded and / or disposable cell culture well plate. These gradients create convection currents within the well that generate flow or within connecting microchannels between wells. A further aspect induces controlled thermal convection currents within wells of a microtiter plate to drive fluid movement.