121results about "Analysis material containers" patented technology

Disclosed here are kits comprising pre-packed stabilizing solutions for stabilizing combinations of biomarkers demonstrating sufficient accuracy and specificity for identifying kidney injuries. Such kits can be better adapted for sample collection at a subject's dwelling, thus easing the burdensome requirement of continuous monitoring for kidney injury.

A system and method for transferring chemical, pharmaceutical, and / or biological material into or out of a container are provided. Further, a use of a transfer interface for accessing the interior of a disposable container is provided. The system comprises a disposable container having at least one port for accessing the interior of the container. The system further comprises a transfer interface connectable to the at least one port. The transfer interface comprises a plurality of extendable transfer elements for collecting samples from the disposable container in a sterile manner. The transfer elements may also be referred to as sampling elements, extractors, or probes. Each of the transfer elements has a corresponding biasing element for retracting the transfer element. The biasing element may be implemented as a spring or as another device capable of applying a biasing force.

Device (1) for receiving biological samples for carrying out a PCR analysis method for determination of pathogenic_microorganisms, in particular pathogenic viruses, especially viruses that cause respiratory diseases, having—a receiving container (2) with a first opening (4), and a closure device (6) which is adapted to the opening (4) of the receiving container (2) such that the opening (4) of the receiving container (2) is able to be closed with the closure device (6), wherein the closure device (6) has a through-opening (20), characterized in that the receiving container contains a liquid preparation composition for point-of-care implementation of a PCR test.

An apparatus for processing and cataloging a sample in a container having a label with initial identification data, the apparatus having a frame; a plurality of cameras mounted to the frame; and a controller system coupled to the cameras, the controller system comprising a controller and a non-transitory memory storing instructions that, when executed by the controller, cause computer processing to be performed to produce a cataloging record output characterizing the sample, the record also including the identification data.

The present disclosure relates to a method of manipulating magnetic beads in a liquid inside a conduit, wherein the method comprises generating a variable magnetic field using at least one magnet or electromagnet to mix the magnetic beads in the liquid; and wherein a biological or chemical species is attached to the surface of the magnetic beads.

Naturally occurring RNA pseudoknots fold into many topologies, yet their formation is poorly understood. Herein, by using high-resolution single-molecule force spectroscopy, the folding pathways of the H-type pseudoknot found in the preQ1-riboswitch in B. subtilis were investigated By holding a single riboswitch RNA molecule in the optical-trap, the structural rearrangements as the end-to-end distance change along the pulling direction, x at a force, F were followed. The data reveal a multistate folding, wherein the intermediate hairpin undergoes a unidirectional conformational switching in the presence of ligand to form the pseudoknot receptor. Specifically-designed mutant RNAs resisted the switching mechanism and resulted in a significantly reduced pseudoknot population (4.5%) compared to the wild-type (100%). The free-energy landscape highlighted two kinetic barriers (ΔG‡) that interrupt the folding pathway. By coupling the exothermic ligand-binding reaction (ΔGbinding=−16 kT) to the folding events, the nascent transcript ensures successful barrier crossing, thus favoring the pseudoknot conformation.

The invention provides a blood absorption retainer, a retainer containing box and a sample elution assembly, the blood absorption retainer comprises a long-strip-shaped support, a connector is arranged at the front end of the support, a check block is arranged at the rear end of the support, and a moisture absorption head with a plurality of micropores is installed on the connector. The retainer accommodating box comprises an upper part and a lower part, and a plurality of partition plates are arranged at the lower part to form an accommodating space of the blood absorption retainer; the upper part comprises a left side cover and a right side cover which can be buckled together, and the left side cover and the right side cover are connected with the lower part through rotating shafts or connecting pieces. The blood absorption retainer is matched with the retainer accommodating box, so that rapid quantitative sampling of non-medical personnel can be realized, the sample can be remotely moved, and the device is suitable for remote medical industry application. The sample elution assembly comprises a pore plate and a retainer bracket which are matched for use, so that a large number of samples can be eluted at one time, and the sample elution assembly can be operated on a machine to improve the detection efficiency.

Disclosed is a test system (100) comprising a test apparatus (100, 400). The test apparatus includes a pool (102) having a volume and an inlet (106, 408) for filling the volume with a test fluid (108, 414). An inner surface (114) of the pool comprises an amount of a viscosity modifying reagent (110, 410) in a dried format. The system also includes an immunochromatography assay strip (104, 502). The viscosity modifying reagent comprises a viscosity-removing salt. The salt is configured to precipitate a viscosity-causing substance present in the test fluid. The immunochromatography assay strip is to be entered through the inlet to be in contact with the test fluid, when in use. The system facilitates processing of viscous fluids such as saliva for rapid diagnostic testing using lateral flow-based assays.

Described is a differential scanning calorimeter (DSC) instrument capable of performing analyses of multiple samples at the same time. Some embodiments of DSC instruments described herein include a thermal substrate that provides a substantially uniform temperature across a surface of the substrate. A plurality of DSC units is in thermal communication with the substrate, for example, by mounting the units directly to the surface of the substrate. Each DSC unit includes a second thermal substrate for further thermal isolation, and a reference platform and sample platform to receive a reference cell and a sample cell, respectively. A thermoelectric device is disposed between each platform and the second thermal substrate. Optionally, the reference and sample cells may be disposable chips that can be discarded after measurement are performed, thereby reducing or eliminating the need to clean instrument components to prevent cross-contamination for subsequent instrument operation.

To improve a test strip assembly having cavities, the test strip assembly used for mainly analyzing reagents or samples; in particular, to provide an arrangement in which reagents or samples used are treated with as less loss as possible.SOLUTION: A test strip assembly 10 is suitable for executing different types of chemical, biological, or biochemical tests and evaluating them by using an appropriate analyzer. The test strip assembly 10 has a first area 30 having at least one container 20 and a second area 40 having at least one container 20. The containers 20 in the first area 30 include a transparent and flat bottom, and the containers 20 in the second area 40 include a V-shaped or U-shaped bottom.SELECTED DRAWING: Figure 3a

The present invention discloses a device for detecting an analyte in a liquid sample, the device comprising: a sample chamber for receiving the liquid sample, the sample chamber comprising an opening and a side wall defining a chamber body; the test cavity is in fluid communication with the sample cavity, the test cavity is provided with an opening, the opening is arranged to enable a test element to be inserted into the test cavity through the opening, and the test element is provided with a test area; the first cover body is used for sealing the opening of the testing cavity, by utilizing the device, an analyzed substance in a liquid sample can be tested, and the device is particularly suitable for testing by a family.

The invention discloses a device for testing an analyte in a liquid sample, and the device includes: a sample chamber for receiving the liquid sample, where the sample chamber includes an opening and side walls enclosing a chamber; a detection chamber, where the detection chamber is in fluid communication with the sample chamber, the detection chamber is provided with the opening through which a testing element is inserted into the detection chamber, and the testing element has a testing area; and a first cover, where the first cover is used for sealing the opening of the detection chamber. The device can be used for testing the analyte in the liquid sample and especially suitable for home self-testing.

Methods of forming an integrated device, and in particular forming one or more sample wells in an integrated device, are described. The methods may involve forming a metal stack over a cladding layer, forming an aperture in the metal stack, forming first spacer material within the aperture, and forming a sample well by removing some of the cladding layer to extend a depth of the aperture into the cladding layer. In the resulting sample well, at least one portion of the first spacer material is in contact with at least one layer of the metal stack.

The invention relates to a microfluidic chip (1) for testing a chemical, in particular for tertiary crude oil recovery. The aim of the invention is to achieve a high degree of practicability. This is achieved in that the microfluidic chip (1) has a microfluidic channel system (2) for conducting fluid, the microfluidic chip (1) having one or more inlet portals (3, 4) for supplying a chemical and a diluting fluid, in particular salt water, into the microfluidic channel system (2), and the microfluidic channel system (2) comprising the following elements fluidically connected one downstream of the other: - a mixing section (A), which is fluidically connected to the inlet portals (3, 4), for mixing the chemical and the diluting fluid to form a chemical solution; - a stability testing section (B), which has a receiving chamber (6) that preferably widens at least in parts, for examining the stability of the chemical solution in the receiving chamber (6); - a feed section (C), which has a feed opening (16), for feeding an interaction fluid, in particular crude oil, into the chemical solution via the feed opening (16) in order to form a mixture; and - a mixture testing section (D), which has a mixing segment, for examining, in particular observing, the stability of the mixture along the mixing segment. The invention further relates to a method for testing a chemical, in particular for tertiary crude oil recovery or natural gas recovery.

Disclosed is a medical veterinary device for extracting and containing biological material to be processed, wherein the medical veterinary device includes interchangeable pieces for forming a syringe for extracting biological material, a container for the extracted biological material to be processed, and a syringe or system for applying the biological material contained in the container. The disclosure also relates to equipment for processing a biological material contained in the medical veterinary device.

The invention relates a method for producing a pharmaceutical composition, comprising the steps of: providing a liquid collected from a mammal, which liquid comprises cellular constituents of blood, providing a container having an internal surface,contacting said liquid with said internal surface,incubating said liquid contacted with said internal surface for an incubation time, wherein said liquid is agitated with an agitation means at least once during said incubation time, and after said incubation time has passed, obtaining said pharmaceutical composition by steps comprising (1) collecting said liquid or (2) removing part of or the entirety of said cellular constituents from said liquid and collecting the remainder.

Embodiments of the invention comprise a test strip configured to detect one or more metabolites of progesterone in urine, and optionally further detect one or more additional metabolites or hormones in urine within the same test strip. Embodiments of the invention are methods of utilizing such a test strip in association with avoidance of pregnancy, detection of menopause, and in association with fertility planning purposes. Embodiments of the invention are associated with the incorporation of a test strip within a testing kit, optionally further comprising a digital reader.

The present invention provides a device for detecting an analyte in a liquid sample, and the device includes a first chamber for collecting the liquid sample and a second chamber for collecting a liquid sample for determination test; where the first chamber is detachably combined or connected with the second chamber; the first chamber is in communication with the second chamber; and the liquid sample located in the second chamber is a part of the liquid sample in the first chamber; in some embodiments, the second chamber is connected with one traction mechanism, which helps the second chamber depart from the first chamber.

An analyzing system comprises a multi-well sample carrier in which each well has a transparent bottom with a nanostructured surface inside the well. The sample carrier can be installed in a reader device so that each well of the sample carrier is aligned with a respective light guiding unit of the reader device. In use, each light guiding unit directs a beam of excitation light to the bottom of the respective well, and directs a beam of reflected light from the bottom of the respective well. The nanostructured surface acts as a plasmonic sensor to facilitate analysis of the contents of the wells. The system allows highly sensitive quantification and characterisation of biological interactions in real time across multiple wells, and with improvements in yields, quality and production times.

Methods and kits for assessing the propensity of developing urolithiasis, kidney disease, or bladder disease in pets; and compositions to treat such conditions are described herein.

The invention relates to an apparatus for analyzing heterogeneously catalyzed reactions comprising at least one reactor (3) through which a particulate catalyst flows and at least one reactant feed, wherein arranged downstream of each reactor (3) is a separation apparatus (17) for separating the particulate catalyst from a reaction product comprising condensable gases and arranged downstream of the separation apparatus (17) is a liquid separator (31) for separating liquid constituents from the reaction product, wherein the liquid separator (31) comprises a metallic tube (103) and a deflection body (119), wherein the metallic tube (103) is closed at its ends and the deflection body (119) is accommodated in the metallic tube (103) and the metallic tube (103) comprises a side feed (135) at a first end (105) and a gas outlet (113) at a second end (107) and the gas outlet (113) is connected to at least one sample vessel (37). The invention further relates to a process for analyzing heterogeneously catalyzed reactions in the apparatus.

The invention relates a method for producing a pharmaceutical composition, comprising the steps of: providing a liquid collected from a mammal, which liquid comprises cellular constituents of blood, providing a container having an internal surface, contacting said liquid with said internal surface, incubating said liquid contacted with said internal surface for an incubation time, wherein said liquid is agitated with an agitation means at least once during said incubation time, and after said incubation time has passed, obtaining said pharmaceutical composition by steps comprising (1) collecting said liquid or (2) removing part of or the entirety of said cellular constituents from said liquid and collecting the remainder.

A biological liquid collection device designed to draw blood using an "atmospheric-balanced vacuum" to ensure the blood is exposed to the sample atmospheric partial pressure oxygen and partial pressure carbon dioxide levels as found in standard arterial blood gas syringes, resulting in blood gas sample stabilization during collection and a superior vacuum shelf-life by reducing the gas permeation rate through the plastic tube. The biological liquid collection device comprises a collection module for receiving a biological liquid sample, an evacuated container having an open end and a closed end wherein the evacuated container contains the collection module therein, and a closure for closing the open end of the evacuated container. The evacuated container comprises a gas composition that is substantially equal to the gas composition of the atmosphere outside of the evacuated container. A method for forming the atmospherically balanced vacuum collection device is also provided.

A snap-fit uncapping-free urine collection tube, comprising the following components: an outer cap (1), a pierceable membrane (2), an inner clip (3), and a tube body (4). The puncture membrane (2) comprises a base part (5) and a pierceable part (6). The base part (5) is annular, and the pierceable part (6) is round. The outer cap (1) comprises a cylinder body (7) and an inner ring (8). The cylinder body (7) is cylindrical, and the inner ring (8) is internally connected to the cylinder body (7). The inner ring (8) is annular with a round hole in the center. An annular recess is arranged on the inner ring (8). The lower part of the cylinder body (7) is provided with a screw thread and a sealing ring (10). The inner clip (3) is also annular with an outer diameter slightly greater than the inner ring (8). An annular protrusion (9) is arranged on the inner clip (3).

The application discloses a sample container which comprises a main body, a middle cover and an upper cover. The main body is provided with a cavity for storing samples and a cavity opening communicating with the cavity. The middle cover is arranged on the main body and partially covers the cavity opening. The middle cover is provided with a sample inlet channel communicating with the cavity and the outside. The outer peripheral wall of the middle cover is provided with a first limiting portion and a first guide portion. The first limiting portion is located between the first guide portion and the communication position of the sample inlet channel and the outside. The side of the first guide portion facing the first limiting portion is formed with a first guide surface. At least part of the surface of the guide surface is provided in a slope or arc shape. The upper cover is detachably arranged on the middle cover and covers the sample inlet channel. The inner peripheral wall of the upper cover is provided with a second limiting portion and a second guide portion. The second limiting portion is connected with the first limiting portion. The second guide portion is in abutting limiting connection with the first guide portion. The sample container provided by the application has higher efficiency in sample adding operation.

A sealable container for cryopreservation of a biological sample is provided. The sealable container (10) includes a cap (120) and an elongate body (40). The elongate body extends from a handle portion (50) to a specimen portion (70), where the specimen portion is configured to receive a biological sample thereon. The elongate body further includes a closure portion (60) disposed between the handle portion and the specimen portion, where the closure portion is configured to make surface to surface contact with the cap when the specimen portion of the elongate body is fully inserted within the lumen of the cap. At least one of an inner surface of the cap and an outer surface of the elongate body includes a textured area with a textured surface finish. The textured surface finish may improve the seal against liquid nitrogen ingress.

The present invention relates to a method for developing personalized targeted anticancer therapy based on aptamers and systemically modeling individuals in a microfluidic device. In one embodiment, the present invention provides a method for developing targeted therapy comprising maintaining targeted cancer cells in co-culture with non-target non-cancer cells using a microfluidic device modularly arranged within a closed system to develop aptamers. In another embodiment, the present invention provides a method for developing targeted therapy comprising maintaining target cells in co-culture with non-target cells using a microfluidic device modularly arranged in a closed system. In this regard, the present invention provides development of aptamers for relevant targets that are in homeostatic balance with fluidic components modulated by co-culture with non-target cells.