52results about "Analysis material containers" patented technology

The present disclosure relates to a method of manipulating magnetic beads in a liquid inside a conduit, wherein the method comprises generating a variable magnetic field using at least one magnet or electromagnet to mix the magnetic beads in the liquid; and wherein a biological or chemical species is attached to the surface of the magnetic beads.

The invention provides a blood absorption retainer, a retainer containing box and a sample elution assembly, the blood absorption retainer comprises a long-strip-shaped support, a connector is arranged at the front end of the support, a check block is arranged at the rear end of the support, and a moisture absorption head with a plurality of micropores is installed on the connector. The retainer accommodating box comprises an upper part and a lower part, and a plurality of partition plates are arranged at the lower part to form an accommodating space of the blood absorption retainer; the upper part comprises a left side cover and a right side cover which can be buckled together, and the left side cover and the right side cover are connected with the lower part through rotating shafts or connecting pieces. The blood absorption retainer is matched with the retainer accommodating box, so that rapid quantitative sampling of non-medical personnel can be realized, the sample can be remotely moved, and the device is suitable for remote medical industry application. The sample elution assembly comprises a pore plate and a retainer bracket which are matched for use, so that a large number of samples can be eluted at one time, and the sample elution assembly can be operated on a machine to improve the detection efficiency.

Described is a differential scanning calorimeter (DSC) instrument capable of performing analyses of multiple samples at the same time. Some embodiments of DSC instruments described herein include a thermal substrate that provides a substantially uniform temperature across a surface of the substrate. A plurality of DSC units is in thermal communication with the substrate, for example, by mounting the units directly to the surface of the substrate. Each DSC unit includes a second thermal substrate for further thermal isolation, and a reference platform and sample platform to receive a reference cell and a sample cell, respectively. A thermoelectric device is disposed between each platform and the second thermal substrate. Optionally, the reference and sample cells may be disposable chips that can be discarded after measurement are performed, thereby reducing or eliminating the need to clean instrument components to prevent cross-contamination for subsequent instrument operation.

Methods of forming an integrated device, and in particular forming one or more sample wells in an integrated device, are described. The methods may involve forming a metal stack over a cladding layer, forming an aperture in the metal stack, forming first spacer material within the aperture, and forming a sample well by removing some of the cladding layer to extend a depth of the aperture into the cladding layer. In the resulting sample well, at least one portion of the first spacer material is in contact with at least one layer of the metal stack.

Disclosed is a medical veterinary device for extracting and containing biological material to be processed, wherein the medical veterinary device includes interchangeable pieces for forming a syringe for extracting biological material, a container for the extracted biological material to be processed, and a syringe or system for applying the biological material contained in the container. The disclosure also relates to equipment for processing a biological material contained in the medical veterinary device.

Embodiments of the invention comprise a test strip configured to detect one or more metabolites of progesterone in urine, and optionally further detect one or more additional metabolites or hormones in urine within the same test strip. Embodiments of the invention are methods of utilizing such a test strip in association with avoidance of pregnancy, detection of menopause, and in association with fertility planning purposes. Embodiments of the invention are associated with the incorporation of a test strip within a testing kit, optionally further comprising a digital reader.

An analyzing system comprises a multi-well sample carrier in which each well has a transparent bottom with a nanostructured surface inside the well. The sample carrier can be installed in a reader device so that each well of the sample carrier is aligned with a respective light guiding unit of the reader device. In use, each light guiding unit directs a beam of excitation light to the bottom of the respective well, and directs a beam of reflected light from the bottom of the respective well. The nanostructured surface acts as a plasmonic sensor to facilitate analysis of the contents of the wells. The system allows highly sensitive quantification and characterisation of biological interactions in real time across multiple wells, and with improvements in yields, quality and production times.

Methods and kits for assessing the propensity of developing urolithiasis, kidney disease, or bladder disease in pets; and compositions to treat such conditions are described herein.

The invention relates to an apparatus for analyzing heterogeneously catalyzed reactions comprising at least one reactor (3) through which a particulate catalyst flows and at least one reactant feed, wherein arranged downstream of each reactor (3) is a separation apparatus (17) for separating the particulate catalyst from a reaction product comprising condensable gases and arranged downstream of the separation apparatus (17) is a liquid separator (31) for separating liquid constituents from the reaction product, wherein the liquid separator (31) comprises a metallic tube (103) and a deflection body (119), wherein the metallic tube (103) is closed at its ends and the deflection body (119) is accommodated in the metallic tube (103) and the metallic tube (103) comprises a side feed (135) at a first end (105) and a gas outlet (113) at a second end (107) and the gas outlet (113) is connected to at least one sample vessel (37). The invention further relates to a process for analyzing heterogeneously catalyzed reactions in the apparatus.

The invention relates a method for producing a pharmaceutical composition, comprising the steps of: providing a liquid collected from a mammal, which liquid comprises cellular constituents of blood, providing a container having an internal surface, contacting said liquid with said internal surface, incubating said liquid contacted with said internal surface for an incubation time, wherein said liquid is agitated with an agitation means at least once during said incubation time, and after said incubation time has passed, obtaining said pharmaceutical composition by steps comprising (1) collecting said liquid or (2) removing part of or the entirety of said cellular constituents from said liquid and collecting the remainder.

A biological liquid collection device designed to draw blood using an "atmospheric-balanced vacuum" to ensure the blood is exposed to the sample atmospheric partial pressure oxygen and partial pressure carbon dioxide levels as found in standard arterial blood gas syringes, resulting in blood gas sample stabilization during collection and a superior vacuum shelf-life by reducing the gas permeation rate through the plastic tube. The biological liquid collection device comprises a collection module for receiving a biological liquid sample, an evacuated container having an open end and a closed end wherein the evacuated container contains the collection module therein, and a closure for closing the open end of the evacuated container. The evacuated container comprises a gas composition that is substantially equal to the gas composition of the atmosphere outside of the evacuated container. A method for forming the atmospherically balanced vacuum collection device is also provided.

The application discloses a sample container which comprises a main body, a middle cover and an upper cover. The main body is provided with a cavity for storing samples and a cavity opening communicating with the cavity. The middle cover is arranged on the main body and partially covers the cavity opening. The middle cover is provided with a sample inlet channel communicating with the cavity and the outside. The outer peripheral wall of the middle cover is provided with a first limiting portion and a first guide portion. The first limiting portion is located between the first guide portion and the communication position of the sample inlet channel and the outside. The side of the first guide portion facing the first limiting portion is formed with a first guide surface. At least part of the surface of the guide surface is provided in a slope or arc shape. The upper cover is detachably arranged on the middle cover and covers the sample inlet channel. The inner peripheral wall of the upper cover is provided with a second limiting portion and a second guide portion. The second limiting portion is connected with the first limiting portion. The second guide portion is in abutting limiting connection with the first guide portion. The sample container provided by the application has higher efficiency in sample adding operation.

The present invention relates to a method for developing personalized targeted anticancer therapy based on aptamers and systemically modeling individuals in a microfluidic device. In one embodiment, the present invention provides a method for developing targeted therapy comprising maintaining targeted cancer cells in co-culture with non-target non-cancer cells using a microfluidic device modularly arranged within a closed system to develop aptamers. In another embodiment, the present invention provides a method for developing targeted therapy comprising maintaining target cells in co-culture with non-target cells using a microfluidic device modularly arranged in a closed system. In this regard, the present invention provides development of aptamers for relevant targets that are in homeostatic balance with fluidic components modulated by co-culture with non-target cells.

A processing assembly for treatment of a sample on a substrate, including: a mounting block including a mounting surface for the substrate; a closure body configured to support a cover member; a closure body arm engaging with the closure body so that rotation of the arm about a pivot axis causes movement of the closure body between the open and closed positions; and a substrate retaining mechanism. The mechanism includes: a cam, and a substrate retaining arm including a cam follower engaging the cam. When the closure body is closed and the cover member engages the substrate, the substrate retaining arm is clear of the substrate, as the closure body arm commences rotation to enable the closure body to rotate towards the open position, but whilst the closure body remains in a closed position, the substrate retaining arm moves into engagement with the substrate, and disengages with the substrate.

In some examples, a syringe coating apparatus comprises a syringe and a centrifuge tube sized to accommodate the syringe. The centrifuge tube includes a reservoir space located at the bottom of the centrifuge tube to collect excess silicone oil during centrifugation. The apparatus may further include a circular support plate configured to center and stabilize the syringe within the centrifuge tube during centrifugation.

A cuvette 300 suitable for use in analysis of biological samples comprises a collection chamber 340 and an analysis chamber 350, wherein 1-60% (parts 310, 330) of the surface area of the analysis cham

The invention relates to the technical field of food safety molecule detection, in particular to a method and a device for detecting food-borne pathogenic microorganisms by using a tubular device based on a Cas12a system, the tubular device is divided into an upper layer and a lower layer according to a mechanical structure, an RPA reaction solution system enrichment target is placed on the upper layer, a CRISPR-Cas12a system is placed on the lower layer, so that physical isolation is formed, and the Cas12a system is arranged on the lower layer. The upper-layer reaction is independently completed. The RPA product enters the lower layer through a gap by moving the tube cover, Cas12a and crRNA recognize and are specifically combined with a target, so that Cas12a trans-cleavage activity is activated, ssDNA marking a fluorophore HEX and a quenching group BHQ1 in a system is cleaved, a fluorescence signal is released, and a result can be observed through a blue light lamp and a filter. Sample detection can be completed within 40 min, the cost is low, operation is easy and convenient, system assembly can be completed at a time in the detection process, repeated uncovering is not needed, the requirement for equipment is low, and the method can be suitable for on-site rapid detection.

This application relates to filter life indicating media and holders. A media sample holder includes a substrate and a plurality of retention assemblies configured to allow attachment of the substrate to an attachment adapter, the plurality of retention assemblies including a retention tab and an opposing flexible release lever arm. The media sample holder can attach a media sample on or near a filter. The media sample held in the media sample holder can have a removal efficiency curve that is different from a removal efficiency curve of the filter. The media sample can be placed at or near the filter for a period of time and then tested to determine a status and / or life of the filter based on a relationship between a remaining life, exposure, or removal efficiency of the filter and an exposure or removal efficiency of the tested media sample.

The present disclosure relates to the field of biological-sample testing. Disclosed is a biological-sample rapid testing device, which is used for conveniently and accurately injecting samples into reaction tanks. The biological-sample rapid testing device comprises a cover, a cylinder and a biological-sample accommodating body, wherein the cylinder comprises a mounting cavity and a plurality of reaction tanks, each reaction tank being in communication with the mounting cavity; the cover is detachably mounted at a top opening of the mounting cavity; and the biological-sample accommodating body is removably located inside the mounting cavity and comprises a sample tank, a liquid discharge pipe and an exhaust flow channel, one end of the liquid discharge pipe being in communication with the sample tank, the other end of the liquid discharge pipe being in communication with the reaction tanks, one end of the exhaust flow channel being in communication with the reaction tanks, and the other end of the exhaust flow channel extending to the top face of the biological-sample accommodating body. By means of the solution, a biological sample can be injected into a reaction tank without requiring other containers, biological samples can be injected into a plurality of reaction tanks in one step by means of flow splitting, the injection quantity is accurate and controllable, and the injection efficiency is high.

A lateral flow test apparatus comprising a housing and a test strip located within the housing. The apparatus further comprises a capillary tube having first and second ends, the first end configured to receive a fluid sample to be tested, and the second opposed end, the housing and the test strip defining an air gap between said second end and a fluid sample receiving region of said test strip, and a user actuable mechanism configured to move said receiving region across said air gap and into contact with said second end, whereby, in use, a sample fluid within said capillary tube is drawn from the capillary tube into said receiving region.

A reaction container 10 for a nucleic acid amplification reaction of a biological sample, the container 10 comprises a wall 12 having an inner surface 14 and an outer surface 16 wherein the inner surf

To provide unique filter holder designs and constitutions and methods appropriate to hold microfilters to collect rare cells and allow performing assays in the filter holder.SOLUTION: A microfilter 1520 comprises a polymer layer formed from epoxy-based photo-definable dry film, and a plurality of apertures each extending through the polymer layer. Rare cells are collected from body fluids to perform assays. The rare cells collected on the microfilter can be used for medical and biological research applications.SELECTED DRAWING: Figure 15

Methods of forming an integrated device, and in particular forming one or more sample wells in an integrated device, are described. The methods may involve forming a metal stack over a cladding layer, forming an aperture in the metal stack, forming first spacer material within the aperture, and forming a sample well by removing some of the cladding layer to extend a depth of the aperture into the cladding layer. In the resulting sample well, at least one portion of the first spacer material is in contact with at least one layer of the metal stack.

A sealable container for storing a biological sample is provided. The sealable container includes a cap and an elongate body. The cap has a proximal open end and a distal end, and a lumen extends from the proximal open end to the distal end. The elongate body extends from a handle portion to a sample portion, the sample portion being configured to receive a biological sample thereon. The elongate body further includes a closure portion disposed between the handle portion and the sample portion, the closure portion being configured to make surface contact with the cap when the sample portion of the elongate body is fully inserted into the lumen of the cap. At least one of an inner surface of the cap and an outer surface of the elongate body includes a textured region having a textured surface finish.

The present invention relates to a sampling device (100,200) comprising a microneedle array assembly (101) comprising at least one microneedle, a body (102) that together with the microneedle array assembly (101) defines a compartment (103) in fluid connection with the microneedles of the microneedle array assembly (101), a first fluid port (104) mouthing into the compartment (103) and having a first diameter d1, and a second fluid port (107) in fluid connection with a suction tube (105) having an inner diameter d2 and extending into the compartment (103), such that an open end (106) of the suction tube (105) is at a distance s from the microneedle array assembly (101). The present invention also relates to a sampling system.

The cutting tool (1) for cutting tube strips (2) comprising two or more sample vessels (2a) comprises a body (3), tube strip holding means (4, 5) comprising a first holding portion (4) configured to hold a sample vessel (2a) and a second holding portion (5) configured to hold another sample vessel (2a), a blade unit (6) comprising a blade (11), the blade unit (6) being configured to be moveable in a direction that is perpendicular to the longitudinal direction of a tube strip (2) hold by the tube strip holding means (4, 5) and to cut the tube strip (2) between the first holding portion (4) and the second holding portion (5), a lever (7) pivotably connected to the body (3) via a pivot axis (8), and a connecting element (9) connecting the lever (7) to the blade unit (6), wherein rotation of the lever (7) about the pivot axis (8) is configured to move the blade unit (6) towards the tube strip holding means (4, 5) to cut the tube strip (2).

A fluidic cartridge kit, including: a fluidic cartridge having an analysis portion and a sample reservoir sealed with a removable shipping closure to contain contents of the sample reservoir during transport; and a dispensing cap; wherein the dispensing cap includes: a closure and dispensing component configured to engage the dispensing cap to the fluidic cartridge and close an opening of the sample reservoir of the fluidic cartridge following removal of the shipping closure from the sample reservoir; a compressible sealing component configured to form a seal between the closure and dispensing component and the sample reservoir and thereby seal the sample reservoir; and a sample release component coupled to the closure and dispensing component and configured to make an opening in a wall of the sealed sample reservoir; and wherein the closure and dispensing component is operable to engage the fluidic cartridge, close the sample reservoir, and compress the compressible sealing component therebetween to seal the sample reservoir, wherein the sample reservoir is partially filled with a sample fluid; wherein the closure and dispensing component is further operable to compress the compressible sealing component and thereby pressurise the sealed sample reservoir and to cause the sample release component to make the opening in the wall of the pressurised sample reservoir; and wherein the closure and dispensing component, the compressible sealing component and the sample release component are configured such that the pressurised sample reservoir is pressurised to a predetermined pressure range that causes at least a portion of the sample fluid to be dispensed through the opening in the pressurised sample reservoir into the analysis portion of the fluidic cartridge.

A histology processing is provided for processing of large samples which do not fit in standard size histology cassettes and which may be labelled using conventional laboratory printing apparatus. The cassette assembly (1) has a box structure (2) with an apertured base and open top face and the internal length to the internal width of the structure is of a ratio from 1.0 to 1.6 and able to receive sample identification information from an automated cassette printing apparatus and a closure (3) for the open upper face of the structure, engageable with the structure to provide a sample enclosure in which the ratio of the width of the sample enclosure to its depth is less than 5:1 and the ratio of the length of the sample enclosure to its depth is less than 6:1 and the depth of the sample enclosure is greater than that of a standard histology processing cassette.