32 results about "Aspiration biopsy" patented technology

The invention relates to the technical field of oral system disease diagnosis, in particular to an oral system onset risk prediction method and system. By combining the five groups of indexes, early evaluation can be effectively performed on the oral cancer, score data reflecting the oral cancer can be obtained, and the grade of the oral cancer and the corresponding deterioration degree can be more intuitively determined through the score data. Compared with an existing method, the method has the advantages that the evaluation result of the patient can be accurately obtained based on a non-needle biopsy means, and the accuracy of the evaluation result is high based on multiple types of indexes.

The utility model provides an endoscope puncture needle with biopsy and ablation functions. The endoscope puncture needle comprises an operation main body, a biopsy needle, a catheter mechanism and a forceps channel fixer, the operation body comprises a limiting handle and a pushing rod, the limiting handle is provided with a first end and a second end which are opposite, one end of the pushing rod movably penetrates through the limiting handle through the first end, and the other end of the pushing rod is provided with a connecting part used for being externally connected with a negative pressure device or an electrode device; a needle inserting depth limiting mechanism matched with the push rod is arranged in the limiting handle, one end of the catheter mechanism is arranged in the limiting handle in a penetrating mode through a second end and communicated with the push rod, and the other end of the catheter mechanism is communicated with the biopsy needle; the forceps channel fixator is movably arranged on the catheter mechanism in a sleeving mode and used for fixing the catheter mechanism and a forceps channel opening of the endoscope. According to the utility model, the problem that the risk of postoperative complications of a patient is increased due to the increase of the number of times of puncture because the needle biopsy procedure and the ablation procedure need to be operated separately and punctured for multiple times in the existing medical procedure needing needle biopsy and interventional ablation treatment can be solved.

The utility model discloses a coaxial puncture needle which comprises an outer tube and an inner core needle, a clamping cap is arranged at the rear end of the inner core needle, a clamping head is arranged at the rear end of the outer tube, the clamping cap and the clamping head can be connected in a clamped mode, the inner core needle is arranged in the outer tube in a penetrating mode from back to front till the clamping head and the clamping cap are connected in a clamped mode, and at the moment, the head of the front end of the inner core needle extends out of the front end of the outer tube. The head of the front end of the inner core needle is composed of a needle tip section and a spin locking section located behind the needle tip section, the taper angle of the needle tip section is 9-15 degrees, and external threads are arranged on the side wall of the spin locking section. According to the coaxial puncture needle, due to the facts that the tip end of the head of the front end of the inner core needle is arranged to be in a pointed cone shape, the side face of the spin locking section is provided with the external threads, and the edge of the front end opening of the outer tube is machined into the cutting edge, the probability that a focus is pushed and disengaged from the needle point is reduced, and the success rate of needle biopsy is increased.

The invention relates to a core biopsy needle (1) for obtaining a tissue sample comprising a hollow outer needle (10) extending along a longitudinal axis (L), and an inner needle (20), which is at least partially arranged or arrangeable within said outer needle along said longitudinal axis (L), wherein said inner needle (20) comprises at least one tissue-holding surface (21), wherein said tissue-holding surface (21) is adapted such that a tissue (3) adheres to the at least one tissue-holding surface (21), when the core biopsy needle (1) is inserted into the tissue (3).

The present invention relates to a combination punch biopsy tool comprising both cutting means cutting a biopsy or sample from a cutaneous or mucosal surface, and a gripping part for catching and safe-handling of the biopsy or sample. In particular, the present invention relates to a punch biopsy tool for providing a skin or mucous membrane or tissue sample (15) comprising a cutting edge (1) and gripping means (2, 2a, 2b) for gripping a biopsy sample, wherein the cutting edge (1) is positioned at a first end of the punch biopsy tool, while the gripping means (2, 2a, 2b) are positioned at a second end of the punch biopsy tool, both the cutting edge (1) and the gripping means (2, 2a, 2b) are secured to a central body.

The invention provides a coaxial puncture needle beneficial to implantation of gelatin sponge, which comprises a needle tube assembly and a needle rod assembly, and the needle rod assembly is nested in the needle tube assembly; the needle tube assembly comprises a needle tube body and a needle base, the needle base and the needle tube body are arranged in a sleeved mode, and the needle rod assembly penetrates into the needle base and the needle tube body. A horn mouth is formed in the end, away from the needle tube body, of the needle base and used for the needle rod assembly to plug the gelatin sponge into the needle tube body. A visible window is formed in the connecting portion of the needle tube body and the needle base. The needle has the advantages that the flat-head needle rod is additionally arranged on the basis of an original pointed-head needle rod, gelatin sponge is conveniently stuffed into the coaxial needle through the flat-head needle rod, the aim of stopping bleeding rapidly, conveniently and effectively is achieved, and the most common complication bleeding in needle biopsy is greatly reduced.

1. The name of the design product: core wire lock (3) for ultrasound suction biopsy needle. 2. The use of the design product: used for locking the core wire of the ultrasound suction biopsy needle, facilitating the storage of the core wire. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: design 1 perspective view. 5. Design 1 is designated as the basic design.

1. The name of the design product: core wire lock (5) for ultrasound suction biopsy needle. 2. The use of the design product: used for locking the core wire of the ultrasound suction biopsy needle, facilitating the storage of the core wire. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: design 1 perspective view. 5. Design 1 is designated as the basic design.

A punch biopsy apparatus to quickly and simply excise a sample of a chosen size and depth while preserving specimen morphology along with an independently operated mechanism to close the excision site. This design includes a body with a cylindrical needle to create a circular incision around the tissue, an independently rotated blade located within the cylindrical needle for excision at the base of the tissue, a plunger to allow release of the specimen, and a compartment for expulsion of skin glue, or another substance, configured to succinctly close the incision site to close the wound. This configuration allows punch biopsies to be performed efficiently with reduced technical skill, number of surgical instruments, and time required for the procedure.

The utility model relates to a coaxial puncture needle with side hole drainage, which comprises a metal needle sheath and a metal needle core coaxially arranged in the metal needle sheath in a penetrating manner, and further comprises a drainage component sleeved on the metal needle sheath, the metal needle sheath comprises a hollow tube body and a needle sheath needle seat arranged at the tail end of the hollow tube body, and at least one drainage side hole is formed in the side wall of the hollow tube body; the drainage assembly comprises a drainage main pipe arranged on the outer side of the drainage side hole in a sleeving mode and a drainage side pipe communicated with the drainage main pipe. One end of the drainage side tube is correspondingly communicated with the drainage side hole of the metal needle sheath, and the other end of the drainage side tube is communicated with the drainage bottle. Compared with the prior art, the coaxial puncture needle has the advantages that blood accumulation and blockage of the needle sheath caused by bleeding during repeated needle biopsy can be avoided, and meanwhile, the problem of blood drop splashing caused by repeated puncture of the puncture needle can be avoided.

The invention relates to the technical field of medicine, and particularly discloses a liver cirrhosis specific intestinal flora marker composition and application of the liver cirrhosis specific intestinal flora marker composition in noninvasive diagnosis. The intestinal microbial flora is selected from the group consisting of clostridium, Bacteroides, Thalictrum, Wehonor genus, Streptococcus genus, Klebsiella genus, and Prevotella genus; according to the method, a non-invasive solution is provided for screening and diagnosis of liver cirrhosis by detecting a synergistic change mode of specific florae such as clostridium, bacteroides, thickenella, prevotella, Wehonor, streptococcus and klebsiella in an excrement sample; the limitation that traditional liver needle biopsy is invasive and imaging examination is insensitive to early-stage lesions is avoided.

The invention relates to the technical field of medical instruments, in particular to an aspiration biopsy needle for tumor tissue, a guide frame comprises a guide disc, U-shaped side guide plates are fixedly connected to the outer wall of the guide disc in an annular array mode, and columnar vertical connecting rods are fixedly connected to the bottom of the guide disc in an annular array mode; by arranging the guide frame and the positioning piece, precise positioning and stable fixing of the tumor tissue needle biopsy needle are achieved, through cooperation of the guide frame and the vacuum adsorption block, the whole device can be quickly and firmly positioned at the part, needing to be punctured, of a patient, a stable foundation is provided for subsequent operation, and the operation efficiency is improved. An electric push rod pushes a rotating block to move downwards to drive a series of linkage structures, so that a clamping block can be flexibly adjusted and accurately fixed according to the position of a puncture needle sliding tube, it is ensured that the puncture needle cannot deviate in the insertion process, and the puncture accuracy and success rate are greatly improved; and extra pain and risk brought to a patient due to inaccurate puncture are effectively reduced.

This invention provides a needle for bone and soft tissue tumor biopsy, comprising a needle body, a ring-taking probe, and a pusher. The needle body includes an outer cannula and a core. A channel is formed through the inner part of the outer cannula. The core is inserted into and exits the channel during puncture. The two ends of the outer cannula are a first end and a second end, respectively. The two ends of the core are a third end and a fourth end, respectively. The third end is a needle tip that extends beyond the first end, and the fourth end is used to engage with the second end to form a handle. A depth fixation device is installed on the outer wall of the outer cannula for adsorption onto the tissue surface. The ring-taking probe is inserted into the channel of the outer cannula after the core is removed to extract tissue samples. The distal inner wall surface of the ring-taking probe has a barbed structure. The pusher is inserted into the outer cannula after sample extraction to completely push out any remaining tissue from the outer cannula. This invention can improve the accuracy and comfort of bone and soft tissue tumor biopsy, reduce the sampling failure rate during puncture, and increase the sample volume.

An inner core is telescopically arranged in a needle tube, one end of the needle tube is concentrically fixed with a sleeve through a Luer taper, a needle head is arranged at the other end of the needle tube, a boosting tube is sleeved outside the rear section of the needle tube, a sheath tube is sleeved outside the front section of the needle tube, and the needle head extends to the outside of the sheath tube. The sheath tube is arranged at the front end of the core rod through the end socket fixing seat, the front section of the core rod is sleeved with an adjusting cylinder in a sliding mode, the rear section of the core rod is sleeved with the sleeve in a sliding mode, an adjusting ring is arranged between the adjusting cylinder and the sleeve, a first adjusting screw is arranged between the adjusting ring and the core rod, and a second adjusting screw is arranged on the side portion of the adjusting cylinder. The ultrasonic needle biopsy needle is convenient to use, wider in applicability and capable of effectively improving the sampling effect.

The utility model relates to the technical field of needle biopsy auxiliary tools, in particular to a high-comfort-degree needle biopsy body position fixing suit which comprises a supporting plate, an anti-skid pad is installed on the top of the supporting plate, a headrest block is arranged on one side of the anti-skid pad, a breathing opening is formed in the surface of the headrest block, upper arm cuffs are arranged on the two sides of the anti-skid pad, and a lower arm cuff is arranged on the other side of the anti-skid pad. The upper arm cuffs are connected and fixed through a binding band, the upper arm cuffs are of a cylindrical structure, and an elastic band is installed at an opening of the upper arm cuffs. According to the high-comfort-degree needle biopsy body position fixing set, the non-slip mat is installed at the top of the supporting plate, a soft and stable supporting surface is provided, compression of the hard supporting plate on the skin of a patient is reduced, and pressing pain or skin injury is effectively prevented. The 10-degree inclined design of the headrest block conforms to the human engineering principle, provides good support for the neck of the patient, and relieves neck discomfort. Due to the design of the cylindrical structure and the elastic band of the upper arm cuff, the arm of the patient can be firmly fixed, blood circulation of the arm is guaranteed, and discomfort is reduced.

The utility model relates to the field of animal disease examination, in particular to a needle biopsy tool for animal disease examination. The existing needle biopsy tool has the problems that the operation is not convenient enough, and the biopsy result is inaccurate due to the shaking of a puncture needle in an animal body. The utility model discloses a needle biopsy tool for animal disease examination. The needle biopsy tool comprises a fixed table and the like, four straight grooves are formed in the fixing table, fixing rods are placed in the four straight grooves of the fixing table, and the lower portions of the four fixing rods are connected with nuts through threads. The medical staff screws the threaded rod, the threaded rod moves to limit the first universal ball, and the first universal ball can limit the guide rod, the puncture needle and the needle tube, so that shaking generated after the puncture needle is inserted into an animal body is reduced, and damage to the biopsy animal is reduced.

The utility model relates to the technical field of medical apparatuses and instruments, and provides an ablation device which comprises an operating mechanism, a needle feeding mechanism, a needle feeding mechanism and an ablation device. A catheter, the proximal end of which is disposed in the operating support body; the hollow ablation needle is movably arranged in the needle inlet tube, the operation supporting body and the catheter in a penetrating mode, the far end of the hollow ablation needle can stretch out of the catheter or retract into the catheter, an axially-through needle passage is formed in the hollow ablation needle, and the hollow ablation needle can conduct ablation operation and needle biopsy and collect biopsy tissue through the needle passage; the hollow ablation needle is detachably connected with the needle inlet tube through the detachable assembly so that the hollow ablation needle can be separated from the operating mechanism and the catheter, and the ablation device has the ablation treatment function and the biopsy function and is simple in structure and convenient to disassemble and assemble.

A kind of skin scale for operation, mainly by the transverse scale plate and longitudinal scale plate connected with each other vertically, is connected with detachable bandage by connecting block.The wire mesh structure with adjustable spacing is arranged between scale plate, including transverse and longitudinal arrangement of metal wire.Scale plate surface is provided with accurate scale, to facilitate direct measurement.Longitudinal metal wire spacing is controlled by screw adjusting mechanism, and transverse metal wire adopts magnetic type sliding fixing device to realize quick positioning.Bandage realizes quick disassembly and assembly by buckle type connector.The present application is manufactured by medical grade material, with good biocompatibility and perspective development nature.The device solves the measurement error problem caused by body position change, skin stretching and other factors in traditional operation positioning, and can provide stable and reliable body surface positioning reference.It has simple structure, convenient operation, and can be widely applied to orthopedic surgery, tumor biopsy and other medical operations requiring accurate body surface positioning.

1. The name of the design product: core wire lock (2) for ultrasound suction biopsy needle. 2. The use of the design product: used for locking the core wire of the ultrasound suction biopsy needle, facilitating the storage of the core wire. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: design 1 perspective view. 5. Design 1 is designated as the basic design.

This utility model relates to a biopsy needle, mainly used for sampling tissue and liquid samples. The biopsy needle includes a handle, a puncture needle, a sampling needle, a spiral sampling head, and a pinch handle. The tip of the puncture needle is equipped with serrated edges, which can effectively cut the tissue, reduce resistance during puncture, and improve puncture efficiency. The spiral sampling head of the sampling needle cuts the tissue by rotation, ensuring sampling accuracy and integrity, avoiding the problems of incomplete sampling or tissue damage in traditional biopsy needle operations. The spiral sampling head is threadedly connected to the needle tube, ensuring the stability and safety of the sampling head during operation. The pinch handle has anti-slip textures on its surface to enhance grip stability and is equipped with a connector for connection to a syringe or tubing for convenient liquid sampling. Furthermore, the graduated ring on the outside of the puncture needle helps the operator accurately control the puncture depth, avoiding accidental injury during operation.

The utility model discloses a bone marrow aspiration biopsy needle in the related technical field of aspiration biopsy needles, which comprises a puncture needle main body and a needle length adjusting nut sleeve, one end of the puncture needle main body is connected with an adjusting screw rod, the outer side of the adjusting screw rod is sleeved with the needle length adjusting nut sleeve, and the needle length adjusting nut sleeve is connected with the puncture needle main body. A locking plane is milled on the outer diameter of the needle length adjusting nut sleeve, and a nut locking jackscrew is installed on the locking plane. The length scale is arranged on the outer side of the adjusting screw rod of the puncture needle, the elongation of the puncture needle can be visually checked through the length scale, it is ensured that the puncture process is in place at a time, and pain is brought to a patient in the puncture process; a needle core locking jackscrew is arranged on the outer side of the needle core fixing end cap, the adjusting nut sleeve and the needle core fixing end cap are locked and fixed through the jackscrew, and the situation that the needle core and the main body rotate relatively in the puncture process, and the puncture process is affected is avoided.

The invention belongs to the technical field of biomedicine, and relates to a methylation characteristic data detection method and a detection kit. The method comprises the following steps: extracting genome DNA from a tissue sample; performing high-throughput detection on the methylation level of the CpG site in the genome DNA to obtain a detection result; constructing a methylation characteristic analysis model based on the methylation state of the CpG site in the detection result; generating methylation feature data of the tissue sample through the model; the methylation characteristic data is used for detecting a kidney cancer specific DNA methylation marker associated with the abnormal tricarboxylic acid cycle metabolism. Through integration of multi-omics data and strict screening standards, detection of needle biopsy and surgical resection samples is supported, compatibility is high, generation and analysis of methylation data are focused, and disease diagnosis or treatment is avoided.

A device may comprise a collection tube comprising an interior surface defining an interior space, the collection tube comprising a first end and a second end defining a luer; a tissue collection magazine received within the interior space of the collection tube; a sealing cap comprising a first end configured to receive one end of the tissue collection magazine and couple to the first end of the collection tube, the sealing cap comprising a second end configured to selectively receive one of a work element of a biopsy device, a vacuum source and a source of a fluid; and a tube-shaped mesh screen disposed within the tissue collection magazine and facing the interior surface, the tube-shaped mesh screen comprising an open end closest to the sealing cap and a closed end furthest away from the sealing cap.

1. The name of the design product: core wire lock (1) for ultrasound suction biopsy needle. 2. The use of the design product: used for locking the core wire of the ultrasound suction biopsy needle, facilitating the storage of the core wire. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: design 1 perspective view. 5. Design 1 is designated as the basic design.

The utility model discloses a developing type puncture needle suite which comprises a hollow outer needle tube and a solid inner needle rod which are connected with an external biopsy gun device, wherein the solid inner needle rod is positioned on an inner cavity of the hollow outer needle tube; a sampling groove is formed in the end, away from the biopsy gun device, of the solid inner needle rod, and at least one section of inner ultrasonic developing area and at least one section of outer ultrasonic developing area which are used for assisting in recognizing the position where puncture reaches a target area and assisting in confirming the sampling position and the sampling length are arranged on the sampling groove and the hollow outer needle tube respectively. Before the biopsy gun device acts, the projection, located at the central axis position of the hollow outer needle tube, of the outer ultrasonic developing area and the projection, located at the central axis position of the hollow outer needle tube, of the inner ultrasonic developing area coincide. The needle biopsy device has the advantages of being capable of assisting an operator in identifying the position of a target area where puncture arrives and accurately confirming the sampling position and the sampling length so as to improve the needle biopsy precision.

The aspiration biopsy needle comprises an outer sleeve and an inner core, the inner core is arranged in the outer sleeve, one end of the outer sleeve is sleeved with an outer sleeve holding piece, and the outer sleeve holding piece is connected with an outer sleeve fixing assembly; a cutting groove is formed in the end, arranged in the outer sleeve, of the inner core, the inner core is hollow and communicated with the cutting groove, the other end of the inner core is sleeved with an inner core holding piece, the inner core holding piece is connected with a negative pressure device connector, the open end of the inner core is communicated with the negative pressure device connector, and a core body, arranged outside the outer sleeve, of the inner core is sleeved with a limiting assembly. According to the utility model, a proper sampling depth can be selected according to actual conditions, so that the success rate of biopsy puncture sampling is greatly improved, consumables are reduced, and injury to patients is reduced.

The utility model relates to the technical field of medical supplies, in particular to a prostate needle biopsy tissue specimen box which comprises a main body and a box cover mutually buckled with the main body, storage grooves are arranged on the main body, embedding boxes are placed in the storage grooves, tissue gaskets are placed in the embedding boxes, and the tissue gaskets are placed in the box cover. The tissue gasket is soaked with stationary liquid, a dyeing area is arranged at one end of the tissue gasket, and tissue dyeing liquid is carried in the dyeing area. The tissue specimen box is integrally designed and can be used for placing and temporarily storing all prostate needle biopsy tissues of a patient; a puncture sample is separated through the storage tank and the embedding box, and a tissue gasket in the embedding box is provided with tissue staining fluid, so that a doctor can conveniently perform staining marking on each puncture tissue so as to identify the head and tail ends of the tissue, and by combining a subsequent pathological report box imaging result, spatial pathological analysis can be performed, and accurate positioning of tumor tissue is facilitated.

The invention relates to the technical field of urinary system disease diagnosis, in particular to a urinary system onset risk prediction method and system. By combining the five groups of indexes, prostate cancer can be effectively evaluated in the early stage, score data reflecting the prostate cancer can be obtained, and the grade of the prostate cancer and the corresponding deterioration degree can be more intuitively determined through the score data. Compared with an existing method, the method has the advantages that the evaluation result of the patient can be accurately obtained based on a non-needle biopsy means, and the accuracy of the evaluation result is high based on multiple types of indexes.

The utility model discloses a CT (computed tomography) guided non-vascular intervention auxiliary needle inserting angle adjusting device, which relates to the technical field of needle biopsy angle positioning auxiliary devices, and comprises a base, a horizontal rod and an angle scale, the horizontal rod is connected with a support column through a height adjusting rod, and the bottom end of the support column is connected with the top surface of the base; the angle scale is arranged on the bottom surface of the horizontal rod; two first holes are drilled in one end of the horizontal rod, second holes are drilled in the two ends of each height adjusting rod, the two second holes located in the top end are connected with the corresponding first holes through first bolts, and two third holes are drilled in the top end of the supporting column. The two third holes are connected with the second holes in the bottom ends of the corresponding height adjusting rods through second bolts, and the distance between the centers of the two first holes is equal to the distance between the centers of the two third holes. According to the utility model, the horizontal reference line is introduced, so that the absolute angle is accurately adjusted, and the accuracy and the safety of needle biopsy are improved.

The invention relates to an EDTA (Ethylene Diamine Tetraacetic Acid) decalcification device with multi-stage filtering and circulating functions. The EDTA decalcification device comprises a dissolving frame and a lower contact assembly, the first electric push rod is fixedly connected to the top of the dissolving frame, the lower contact assembly comprises a second vacuum pump, and the second vacuum pump is connected to the bottom of the dissolving frame through bolts. The reagent is prepared from sodium hydroxide, disodium ethylene diamine tetraacetate dihydrate, deionized water, sodium hydroxide and a Tris-HCl buffer solution. A bone focus with active metabolism is recognized through PET-CT scanning, bone needle biopsy is conducted under the guidance of B-mode ultrasound / CT, a bone tissue sample is obtained, and the sample can be moved into the decalcification device to be dissolved. According to the EDTA decalcification device with the multi-stage filtering and circulating functions, the cavity forms a negative pressure state, the contact needle is in contact with the surface of a bone sheet, and the bone sheet is adsorbed through negative pressure difference, so that external decalcification liquid enters the flow guide cavity through pores of the bone sheet, the decalcification liquid is effectively driven and penetrates through the whole bone sheet, and the decalcification effect is improved. Liquid transmission from one end to the other end is realized, and the decalcification time is shortened.