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Antibacterial medical implant surface

A technology for implanting devices and photoresist layers, which can be used in drug delivery, pharmaceutical formulations, medical science, etc., and can solve problems such as random structural patterns, sizes and specifications that are not suitable for medical implants

Active Publication Date: 2019-12-27
IBM CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Known methods for fabricating medical devices with textured surfaces may produce random patterns of structures, or may produce structures of dimensions and specifications that are not suitable for use in medical implant devices

Method used

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  • Antibacterial medical implant surface
  • Antibacterial medical implant surface
  • Antibacterial medical implant surface

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Embodiment Construction

[0032] Medical implants are becoming more common as new technologies become available to treat ailments associated with disease and aging. However, complete sterilization of implanted devices by conventional means is difficult, leading to the introduction of infectious substances into the body along with surfaces that can provide a bacterial matrix to form biofilms. Not only can this biofilm lead to potentially serious infection and disease, but it often requires surgery to remove the infectious material from the body. In addition, the growth of bacterial films on the surface of implanted medical devices, including, for example, pacemakers and orthopedic implants, can also prevent the proper operation of the device and sometimes lead to device failure.

[0033] There is a need to reduce or eliminate bacterial infections associated with medical devices to improve patient outcomes. Special considerations, such as biocompatibility, may be required to prevent infection. Conventi...

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Abstract

Aspects include methods of fabricating antibacterial surfaces for medical implant devices including patterning a photoresist layer on a silicon substrate and etching the silicon to generate a plurality of nano-pillars. Aspects also include removing the photoresist layer from the structure and coating the plurality of nano-pillars with a biocompatible film. Aspects also include a system for preventing bacterial infection associated with medical implants including a thin silicon film including a plurality of nano-pillars.

Description

technical field [0001] The present invention relates generally to medical implant devices, and more particularly, to bioinspired antimicrobial surfaces for medical implant devices. Background technique [0002] Bacterial infection associated with medical implants, such as orthopedic and dental implants, is an important challenge. Medical implants can be made of various materials and manufactured according to different methods. Bacteria may come into contact with medical implants in various ways prior to or even during the surgical implantation process, for example, due to incomplete or ineffective sterilization of the medical implant device, contamination from the patient such as the patient's skin, contamination disinfectants, or contaminants associated with surgical instruments. After implantation, bacterial cell membranes can form on the surface of the medical device. As the world's population ages and undergoes more frequent implant procedures, the likelihood of such ...

Claims

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Application Information

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IPC IPC(8): A61L27/30H01L21/00
CPCB81C1/00206B81B2203/0361B81B2207/056A61L27/06A61L27/306A61L27/34A61L27/50A61L2400/18A61L2400/12A61L2420/02A61L31/06A61L31/088A61L31/10A61L31/16A61L2300/406A61L2300/606A61L2420/08B82B3/0019B82B3/0033
Inventor 胡欢S.吉福德E.金瑟S.扎法尔虞蓉卿
Owner IBM CORP
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