80 results about "ORAL DRYNESS" patented technology

According to the novel mandibular protraction appliance and the digitization-based manufacturing method thereof, a vestibular shield is arranged on the lip side of the lower anterior teeth of the mandibular protraction appliance, and the appliance can effectively seal the oral cavity and improve the dry mouth symptom possibly occurring when a traditional mandibular protraction appliance is worn; the common mouth breathing problem of patients with obstructive sleep apnea hypopnea syndrome (OSAHS) is solved, and the limitation of lip inclination of lower anterior teeth caused by a traditional mandibular advancement appliance is reduced more remarkably.

The invention belongs to the technical field of health-care food, and particularly relates to a composition and oral drops with the effects of dispelling the effects of alcohol, protecting the liver and relieving hangover as well as a preparation method and application of the composition and the oral drops. The invention provides a composition taking silybin eutectic crystal, curcumin eutectic crystal, ampelopsis grossedentata extract, pyrroloquinoline quinone disodium salt, reduced glutathione, alpha-ketoglutaric acid, vitamin, hericium erinaceus extract, frankincense extract, licorice extract and the like as main active ingredients, and the composition is subjected to scientific formula screening and functional verification, and has the advantages that the composition has the obvious curative effect, and the curative effect is obvious; the traditional Chinese medicine composition can effectively improve the metabolism of ethanol, protect liver and gastric mucosa, and is helpful for relieving hangover-related symptoms such as fatigue, thirst, sleepiness, headache, dry mouth, stomachache, nausea, hypomnesis, inattention and the like.

The invention discloses a quantitative evaluation method for the dry mouth degree of a wine product after drinking, which comprises the following steps: step 1, tested mice are divided into a control group and a test group, the mice in the control group do not ingest alcohol, the test group performs single gavage on wine products with different dry mouth degrees, and the total amount of alcohol in the single gavage on the wine products of the mice in the test group is the same; and step 2, at different time points, detecting the change conditions of the mouth dryness biochemical index contents of the mice in the control group and the test group, scoring the mouth dryness degree, and evaluating the mouth dryness degree of the corresponding wine body drunk by the mice according to the score. The method has the advantages of being easy and convenient to operate, high in sensitivity, high in practicability and the like, subjective evaluation can be conducted on the dry mouth effect of the wine sample instead of a crowd test, damage to the human body is reduced, the evaluation result is more objective, an evaluation system for the comfort degree of the wine after drinking is widened, and a new evaluation method is provided for further researching and improving the comfort degree of the wine product after drinking.

The invention discloses a throat nourishing and clearing granule as well as a preparation method and application thereof, and belongs to the field of pharmaceutical preparations, the throat nourishing and clearing granule comprises the following components in parts by weight: 10-20 parts of radix rehmanniae recen, 10-20 parts of radix ophiopogonis, 10-20 parts of radix paeoniae alba, 5-15 parts of moutan bark, 5-15 parts of thunberg fritillary bulb, 10-20 parts of radix scrophulariae and 5-15 parts of lily; the preparation method comprises the following steps: S1, preparing raw materials; s2, crushing; s3, mixing; s4, performing granulation; s5, drying; s6, screening to obtain prepared particles; the granules for nourishing and clearing heat from throat provided by the invention can nourish yin and clear heat, remove stasis and relieve sore throat, relieve symptoms such as throat pain, dry mouth and pharynx, throat itching, foreign body sensation of throat and the like, have a good clinical curative effect and few side effects, and are especially suitable for yin deficiency and lung heat patients with chronic pharyngolaryngitis delayed and unhealed, recurrent attack, dry oropharynx, dysphoria in both heart and heart, dry cough without phlegm, less and sticky phlegm and the like.

The invention discloses a traditional Chinese medicine compound composition with an effect of preventing and treating radioactive injury as well as a preparation method and application thereof. The traditional Chinese medicine compound composition is prepared from 5-15 parts of American ginseng, 3-6 parts of sea-buckthorn and 10-30 parts of rhizoma polygonati. The composition is proportioned and optimized according to the theory of treatment based on syndrome differentiation, and the medicines are combined to achieve the effects of tonifying qi, activating blood and nourishing yin. Clinical experiment results show that the traditional Chinese medicine compound composition provided by the invention has a remarkable effect of preventing and treating radioactive injury, particularly has a remarkable curative effect in the aspects of improving oral mucositis, dry mouth, weakness, sleep disorder and the like after radiotherapy, and is safe in clinical medication.

The invention discloses an ultraviolet rhinitis therapeutic apparatus, and belongs to the technical field of rhinitis therapeutic apparatuses, the ultraviolet rhinitis therapeutic apparatus comprises a therapeutic apparatus main body, an adjusting assembly is assembled in the therapeutic apparatus main body, and a phototherapy assembly is assembled at the end of the adjusting assembly; by arranging the adjusting assembly and the phototherapy assembly, non-invasive fixation and nasal septum protection are achieved, three areas of the protection sleeve are controlled to bulge through a tough piece to be attached to the inner wall of the nasal cavity in a self-adaptive mode, a traditional nose clip mechanical clamping mode is replaced, and the risk of mucous membrane injury, bleeding or structural deformation caused by direct pressing of the nasal septum is avoided; meanwhile, the movable seat slides along the inner cavity of the tail plug under the driving of the screw rod, the inclined end of the movable seat pushes the inclined surface seat to enable the flexible sheet to expand outwards, the corresponding area of the protective sleeve is driven to bulge, the nasal cavity shape difference of different patients is adapted, the fixing stability is improved, and the foreign body sensation is reduced; the secondary problems of dry mouth, throat discomfort and the like caused by mouth breathing are avoided, and the treatment comfort is guaranteed.

Liquid formulation including cevimeline hydrochloride and a combination of at least one sweetener and at least one flavoring agent to mask the bitter taste of cevimeline hydrochloride oral solutions. The liquid formulation may be administered to a patient to alleviate dry mouth symptoms associated with xerostomia and Sjogren's syndrome.

A formulation for treating and alleviating xerostomia is provided. Formulations comprising a humectant (e.g., propylene glycol), a chelating agent (e.g., EDTA and salts thereof), and a transport promoter (e.g., methylsulfonylmethane (MSM)) are provided.

The utility model belongs to the technical field of dental prosthesis design, and particularly discloses a hollow base liquid storage type removable denture which comprises a base and artificial teeth arranged on the base, the base is a hollow base with a liquid storage cavity, the hollow base is provided with a plurality of overflow discharge channels communicated with the liquid storage cavity, and the diameter of the outlet end of each overflow discharge channel is 0.3-1mm; a plurality of tissue surface adsorption structures are arranged on the tissue surface part of the base plate. The removable denture disclosed by the utility model can automatically and slowly release artificial saliva, so that the dry feeling of an oral cavity is reduced; due to the design of the tissue surface adsorption structure on the tissue surface, the contact area between the base plate and the oral cavity tissue is increased, so that the adsorption force is improved.

The utility model discloses a drinking water aerosol inhalation device for radiotherapy patient nursing, which comprises a device main body, a water storage tank, an atomizing cup, an ultrasonic atomizing sheet and a heater, the water storage tank is fixed on one side of the surface of the device main body, the atomizing cup is arranged in the device main body, the ultrasonic atomizing sheet is arranged at the bottom of the atomizing cup, and the heater is arranged on the atomizing cup. The heater is installed in the atomizing cup, heating wires are installed in the heater at equal intervals, a fan is installed at the top of the atomizing cup, a water pump is installed on one side of the bottom of the device body, a corrugated hose is arranged above the device body, and a mouthpiece is arranged at the bottom end of the corrugated hose. The mouth piece not only has a good moistening effect on the oral cavity and can effectively relieve the symptom of dry mouth of a radiotherapy patient, so that water mist inhaled by the patient is kept at a proper temperature, but also is convenient to fix the mouth piece in the mouth, the tightness of the ear hanging rope is adjustable, and the mouth piece is labor-saving and convenient.

The invention discloses a treatment composition to treat nasal or oral dryness and allergy symptoms, and a method for using the same. Certain compositions include xylitol, at least two wetting agents, an aqueous carrier, and other active ingredients, such as a potassium salt, a sodium salt, and a preservative. The composition may be configured as a nasal or oral spray, and oral rinse, or a nasal gel.

The invention provides a yin-nourishing sore-throat-relieving drink composition. The composition is prepared from the following raw materials by weight: 400g of pears, 100g of fructus phyllanthi, 150g of herba houttuyniae, 80g of Chinese dates, 30g of gordon euryale seeds, 15g of honey-fried licorice roots and 15g of Chinese wolfberry fruits. The composition synergistically exerts the effects of relieving cough and reducing sputum, nourishing yin and moistening dryness and clearing away heat and toxic materials through scientific compatibility, is suitable for relieving lung dryness cough, swollen sore throat, dry throat and mouth dryness and other symptoms, and is safe and suitable for long-term drinking due to the fact that most of the raw materials are medicinal and edible.

The invention discloses a TCM syndrome differentiation system for early breast cancer during chemotherapy, including four syndrome types, namely: liver depression and yin deficiency syndrome, corresponding syndrome items are: irritability, thin white tongue coating, forgetfulness, chest and flank distension and pain, dry mouth, hot flashes, chest and abdominal pain, bone pain, abdominal distension, chest tightness; qi and yin deficiency syndrome, corresponding syndrome items are: deep pulse, thin white tongue coating, red tongue, hot flashes, forgetfulness, dry mouth, pale complexion, sore waist and knees, spontaneous sweating, ruddy complexion; spleen deficiency and blood deficiency syndrome, corresponding syndrome items are: pale tongue color, white and greasy tongue coating, pale complexion, dry mouth, poor appetite, thin pulse, fat tongue; qi stagnation and blood stasis syndrome, corresponding syndrome items are: ecchymosis on tongue, blue lips, varicose veins under tongue, stringy pulse, dark complexion, numbness of limbs, oral ulcers. The invention also discloses a construction method and application of the system. The invention provides a theoretical basis for the standardized TCM treatment of patients in the chemotherapy period of early breast cancer, and has broad application prospects.

This product is a lip piece for nasal breathing during sleep. Traditionally, mouthpieces are worn between the upper and lower teeth inside the mouth, but this lip piece is placed between the upper and lower gums and lips, covering the entire lip, and has a slightly elongated ring shape. It utilizes the principle that even ordinary people can achieve nasal and diaphragmatic breathing by opening their mouths wide like singers. One piece can be fitted to set two sizes, slightly elongated vertically and slightly horizontally. This allows for adjustments to the size of the person's mouth and jaw closure, adjustment of the amount of air, and multi-purpose use such as daytime fitting practice or nighttime sleep use. The material is synthetic resin, and you can choose between a harder (plastic) and a softer (elastomer) version. When this product is worn on the lips, the larynx opens, ensuring an open airway during sleep, allowing for smooth nasal breathing, and preventing snoring and sleep apnea. Furthermore, since it prevents mouth breathing even when the mouth is open, it can prevent various problems associated with mouth breathing. It can be used by a wide range of ages, from infants with underdeveloped lower jaws who grind their teeth, to adults with teeth clenching, dry mouth, temporomandibular joint disorders, and elderly people at risk of aspiration, and is harmless. Once the discomfort of wearing it is overcome, it promotes restful sleep with light and safe nasal breathing. Other benefits include improved blood flow to the muscles around the mouth, while at the same time creating a slight tension in the lips, which is good for blood flow to the brain. The lips relax and the salivary glands work, so saliva is produced, but the structure prevents saliva from spilling out of the mouth. The base of the tongue is more easily moved forward, so the epiglottis (the lid for swallowing) moves. It is also expected to help prevent silent aspiration pneumonia.

The present invention relates to a hydrating patch. The hydrating patch (100) comprises a biodegradable and biocompatible absorbent inset (106). The absorbent inset (106) absorbs and retains a liquid, and discharge an absorbed liquid when pressed. The hydrating patch (100) also comprises a biocompatible matrix (102) which supports the absorbent inset (106). The biocompatible matrix (102) is flexible. To attach the biocompatible matrix (102) to a biological membrane, a sticking layer (110) is attached to the biocompatible matrix (102). The hydrating patch (100) can be attached in the oral cavity to alleviate dryness in a person having a dry mouth condition.

The invention discloses a formula and a preparation method of a disease-preventing health-care oral liquid. The health-care food is prepared from the following raw materials in parts by weight: 4 to 6 milliliters of purple perilla seed oil, 5 to 7 milliliters of walnut oil, 100 to 150 milligrams of algal oil, 200 to 250 milligrams of grape seed extract, 50 to 80 milligrams of selenium-enriched yeast, 80 to 120 milligrams of vitamin C, 80 to 120 milligrams of vitamin E, 0.6 to 1.0 milligram of vitamin B1 (thiamine) and 0.6 to 1.0 milligram of vitamin B2 (riboflavin). After being taken by multiple persons for a period of time, the traditional Chinese medicine composition is proved to be safe to take, free of adverse reaction and obvious in health care effect, old people feel weak in action, heavy in whole body, dry in mouth and throat and insomnia and constipation before taking the traditional Chinese medicine composition, symptoms are relieved after taking the traditional Chinese medicine composition, and the traditional Chinese medicine composition is safe to take, free of adverse reaction and obvious in health care effect. Young people are good in working state and honor in spirit, and children are fast in learning progress, good in taste, high in adaptability and beneficial to popularization, and can play a positive role in prevention before illness.

The invention belongs to the technical field of food functional ingredients and biological materials, and particularly discloses an oral cavity lubrication composition, an additive and a preparation method and application of the oral cavity lubrication composition and the additive. The lubrication enhancer is one or more of sugar alcohol compounds; the interface stabilizer is one or more of mammal-derived mucoproteins. According to the oral cavity lubricating composition, the additive and the preparation method and application of the additive, the preparation process is simple and controllable, the lubricating additive has good biocompatibility, the lubricating effect in the oral cavity is remarkably improved, the oral cavity dryness is relieved, the food oral cavity digestion effect is improved, and the additive is suitable for improving oral cavity dysfunctions such as the xerostomia.

The invention relates to the technical field of ventilation treatment devices, and discloses a device for providing ventilation treatment, which comprises a head-mounted assembly, a nose oxygen supply unit and a fixing unit, the head-mounted assembly comprises a hoop ring and a guide sheet attached to the outer arc surface of the hoop ring; the device effectively solves the problems of facial indentation, skin injury and claustrophobic fear caused by traditional head wearing, and remarkably improves the wearing comfort and long-term use willingness; the firm physiological structure of the teeth is used for anchoring, the problem that a traditional nasal oxygen cannula is prone to displacement and falling off is successfully solved, and the stability when the nasal oxygen cannula is worn is greatly improved; the fixing unit keeps the lip closing state in a physical mode, the air leakage condition of the mouth in noninvasive ventilation is avoided, the effectiveness of treatment is ensured, and the oral cavity is effectively prevented from being dry. According to the device, the modularized and quickly detachable design is adopted, a user is allowed to flexibly assemble the device according to requirements, convenience of daily use is considered, and the stability requirement in a specific scene is met.

A formulation for treating xerostomia and alleviating the symptoms of dry mouth is provided. Formulations comprising a humectant (such as propylene glycol), a chelator (such as EDTA and its salts) and a transport enhancer (such as methylsulfonylmethane (MSM)) are provided.

The invention discloses an application of bead exosome-like nano-vesicles in treatment of Sjogren's syndrome. The bead exosome-like nano-vesicle is prepared through a differential centrifugation method and an ultracentrifugation method, and toxicological evaluation shows that the bead exosome-like nano-vesicle has good safety and can be used for in-vivo and in-vitro treatment. In-vivo experiments prove that the Sjogren's syndrome model mouse treated by the bead exosome-like nano-vesicles has significantly increased salivary secretion and significantly improved dry mouth symptom; in-vitro experiments further show that the nano vesicles can also significantly improve the activity and the water secretion function of salivary gland epithelial cells in the Sjogren's syndrome. The exosome-like nano-vesicles are successfully extracted from bead leaves and are creatively used for treating the Sjogren's syndrome, and a brand new thought and a material source are provided for research and development of medicines for treating the Sjogren's syndrome.

The invention discloses artificial saliva and a preparation method of artificial saliva hydrogel. The artificial saliva is prepared from the following raw materials in parts by mass: 0.5 to 1 g of KCl, 0.2 to 0.4 g of K2HPO4, 0.2 to 0.8 g of NaCl, 0.2 to 0.4 g of KH2P O4, 10.04 to 20.8 g of CaCl2, 1.5 to 3 g of Nacaboxymethlecellulose, 60 to 120 mg of brown moss alcohol, 495 to 1000 ml of natural coconut juice and 5 to 10 ml of herba sarcandrae extract. By selecting the glabrous sarcandra herb extract, anti-inflammatory and anti-tumor treatment is realized, so that the traditional Chinese medicine composition has a remarkable effect on dry mouth caused by radiotherapy; through the form of a gel bead preparation, the beverage is more portable and unique in taste. The gel beads serve as one of oral local administration preparations, and after the gel beads are exploded, drugs can target small glands which are located below oral mucosa and secrete saliva, and the rapid drug effect is achieved. Direct local administration to the oral mucosa may provide rapid drug action, activate small salivary glands within the buccal mucosa, while avoiding systemic drug exposure and off-target effect.

Kit and method for treating patients with dry mouth syndrome. The kit includes a dental mouthpiece with one or more near-infrared light sources. Once placed in the oral cavity, it directs the light toward the selected target tissue (salivary glands, submandibular glands, or both) for the treatment of patients with dry mouth syndrome. The kit and method can be used to treat Sjögren's syndrome, patients taking multiple medications, diabetic patients, or patients with a reduced number of salivary glands, resulting in a marked, temporary, or permanent decrease in saliva production.

Disclosed are formulations in the form of mucoadhesive tablets useful for treating symptoms caused by xerostomia (dry mouth). The tablets according to the invention comprise hyaluronic acid, choline alfoscerate and ascorbyl palmitate, and are characterised by two concave surfaces that adapt to the oral and gingival mucosa so as to adhere to the oral vestibules or the palate.

The invention aims to provide a device convenient for mouth dryness nursing of an anesthetized patient, and relates to the technical field of medical instruments, a connector is detachably mounted above a liquid storage bottle, a mounting seat is fixedly arranged on the connector, and a moistener, a spreader and a lip moistener are arranged on the mounting seat; during use, the position of the lip plate is adjusted through the telescopic rod, the two arc-shaped grooves in the lip plate clamp the upper lip and the lower lip of a patient, liquid in the liquid storage bottle is conveyed to the lip plate through the liquid pump, and the liquid is sprayed out through the spraying holes to wet the lips; the upper supporting plate and the lower supporting plate of the dilator abut against the upper teeth and the lower teeth of a patient respectively, the motor in the mounting base drives the upper supporting plate to slide to dilate the oral cavity of the patient, the moistener can stretch into the oral cavity conveniently, the tongue pressing frame of the moistener can press the tongue, it is avoided that the tongue is lifted up to affect operation, and the movable handle is rotated to drive the wetting plate to rotate to be opened. And then the liquid is conveyed to the wetting plate through the infusion pump and is sprayed out through the spraying holes of the wetting plate to wet the oral cavity and the tongue.

The utility model relates to the technical field of oral cavity spraying, and discloses an oral cavity spraying device for a postoperative thirst patient, which comprises an atomizing cylinder, an external connecting ring is arranged at the top of the atomizing cylinder, a sealing cover is clamped above the atomizing cylinder, a limiting ring is fixedly connected to the surface of the external connecting ring, a medicine guide device is inserted into the limiting ring, and the medicine guide device is connected with the atomizing cylinder. An air outlet is formed in the position, connected with the limiting ring, of the external connection ring, a guide rail is arranged above and below the air outlet respectively, and an air guide plate is slidably connected to the outer portion of the atomization cylinder and the outer portion of the guide rail. According to the oral cavity spraying device for the postoperative thirst patient, through the arrangement of the medicine guiding device and the graduated scale, adjuvant medicine or liquid medicine can be conveniently added into the medicine containing pipe, the dry mouth and thirst of the patient can be conveniently and effectively improved, meanwhile, the water drinking amount can be known through the difference between the front liquid level scale and the rear liquid level scale, and quantitative water drinking and quantitative medicine mixing are achieved; the use effect of the oral spray can be improved.

The invention provides a traditional Chinese medicine composition for relieving dry mouth and thirst and a preparation method thereof. The traditional Chinese medicine composition is prepared from 10-20 parts by weight of poria cocos, 10-20 parts by weight of radix puerariae, 5-15 parts by weight of American ginseng, 10-20 parts by weight of rhizoma polygonati, 5-15 parts by weight of dark plum, 3-10 parts by weight of liquorice and 5-15 parts by weight of mint. The invention also provides a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition provided by the invention can effectively relieve dry mouth and thirst caused by sicca syndrome, diabetes mellitus, hyperthyroidism and sleep apnea, or dry mouth and thirst caused by treatment of chronic heart failure patients taking diuretics.

The present invention relates to a composition for relieving oral dryness applicable to head and neck radiotherapy patients, comprising: compound F, citric acid, menthol, vitamin C, xylitol, filler, disintegrant, lubricant; wherein, the compound F is a brand-new compound with M3 PAM activity, which can significantly increase the secretion volume of saliva and can effectively treat xerostomia; in addition, the addition of citric acid and vitamin C in the composition provided by the present invention can not only promote the secretion of saliva, but also accelerate the disintegration rate of tablets and can provide nutrition for patients; and the composition provided by the present invention has few types of excipients, a simple preparation process, and good stability of the prepared tablets.

A mouthpiece device and method for helping human users with congested sinuses breathe freely through their mouths while sleeping while minimizing the risks of dry mouth and drooling. The device fits between the user's jaws and is configured to apply a gentle jaw and lip opening pressure sufficient to at least partially open a sleeping user's jaw and lips while the jaw and lip muscles are relaxed. At the same time, the device is configured to so that when the user, while still sleeping, activates their jaw or lip muscles to swallow, this action overcomes the gentle opening force, allowing the user to easily swallow without conscious effort. Methods of configuring the device shape and opening forces are also taught. These include using implanted sensors, processors, and actuators configured to optimize the opening forces according to user physiology; and / or wireless connection to external sensing and control devices.

The invention discloses ozonized oil and fructus forsythiae composite micro-capsules and a preparation method thereof, and mouthwash for antibacterial repair and a preparation method thereof. The mouthwash comprises the following components: 1-5 wt% of ozonized oil and fructus forsythiae composite micro-capsules, 0.5-2 wt% of carboxymethyl cellulose sodium, 0.1-1 wt% of a sweetening agent, 0.05-0.5 wt% of menthol, 0.1-0.3 wt% of sodium benzoate and the balance of deionized water. The ozonized oil and fructus forsythiae composite microcapsule comprises the following components: 5-15 wt% of ozonized oil, 5-15 wt% of fructus forsythiae, 10-25 wt% of gelatin, 5-15 wt% of Arabic gum and the balance of deionized water. Ozonized oil with strong oxidizing property and fructus forsythiae rich in various antibacterial components are combined, so that complementary advantages of natural components are realized, the antibacterial spectrum is expanded, and the occurrence of allergic phenomena is reduced; the fructus forsythiae and the ozonized oil exist in a micro-capsule form, so that the stability of the ozonized oil is improved, the taste of the ozonized oil is covered, the mouth feel and the smell of the traditional Chinese medicine mouth wash are improved, meanwhile, a protective film can be formed on the surface of an oral mucosa, the dryness of the oral cavity is relieved, the comfort and the compliance in use are improved, and the acceptability of a user is improved.

A mouthpiece device and method for helping human users with congested sinuses breathe freely through their mouths while sleeping while minimizing the risks of dry mouth and drooling. The device fits between the user's jaws and is configured to apply a gentle jaw and lip opening pressure sufficient to at least partially open a sleeping user's jaw and lips while the jaw and lip muscles are relaxed. At the same time, the device is configured to so that when the user, while still sleeping, activates their jaw or lip muscles to swallow, this action overcomes the gentle opening force, allowing the user to easily swallow without conscious effort. Methods of configuring the device shape and opening forces are also taught. These include using implanted sensors, processors, and actuators configured to optimize the opening forces according to user physiology; and / or wireless connection to external sensing and control devices.