441 results about "Nasal inflammation" patented technology

A method for treating a nasal airway to ameliorate one or more symptoms of rhinitis in a patient may involve advancing a treatment tip of a treatment device into a nostril of the patient, contacting nasal mucosa with the treatment tip at a first location overlying an anterior ethmoidal nerve, delivering energy from the treatment tip, to change a property of the anterior ethmoidal nerve, and removing the treatment tip from the nostril.

A method for treating a nasal airway to ameliorate one or more symptoms of rhinitis in a patient may involve activating a radiofrequency console attached to a stylus, bending a shaft of the stylus in at least one location to a desired angle, advancing a distal tip of the radiofrequency stylus into a nostril of the patient, applying pressure against nasal mucosa lining the nasal airway with a treatment surface of the distal tip, and delivering radiofrequency energy from one set of bipolar electrodes on the treatment surface of the distal tip to a second set of bipolar electrodes on the treatment surface, to treat tissue underlying the nasal mucosa, including at least one nasal nerve. The method may also involve contacting the distal tip with an additional tissue at another location and delivering radiofrequency energy to the additional tissue.

The invention discloses bifidobacterium animalis and application thereof in allergic rhinitis products, and belongs to the technical field of microorganisms. The technical problem to be solved is that the existing common allergic rhinitis treatment means cannot meet the requirements of patients on safety, long-acting effect and treatment cycle. The invention provides an animal bifidobacterium subsp. Lactis Def +, and after an effective dose of animal bifidobacterium subsp. Lactis Def + is applied to a subject, the animal bifidobacterium subsp. Lactis Def + is found to be capable of remarkably relieving the allergic rhinitis symptom. Specifically, the symptoms of sneezing, dry nose and rhinocnesmus are reduced; the number of nasal septum mucosa intrinsic layer inflammation infiltration cells and nasal septum mucosa epithelium pathological changes are reduced; the IgA and IgE levels of serum are reduced; the levels of proinflammatory factors IL-4, IL-5 and IL-13 are reduced; the normal spleen index is maintained; the imbalance state of Th1 / Th2 and Th17 / Treg is effectively improved, and the body immunity is improved; a safe and long-acting scheme is provided for allergic rhinitis diseases.

The invention is suitable for the technical field of anti-allergy agents, and provides an anti-allergy agent containing compound plant anti-allergy active ingredients. Comprising 5-10 parts of a bletilla striata extract, 8-15 parts of an aloe extract, 7-12 parts of an angelica sinensis extract, 10-20 parts of a centella asiatica extract, 5-15 parts of a rosemary extract, 8-18 parts of a polygonum cuspidatum extract, 12-25 parts of a scutellaria baicalensis extract, 3-10 parts of a tea extract, 6-15 parts of a liquorice extract and 4-12 parts of a matricaria recutita extract. The preparation method of the anti-allergy agent containing the compound plant anti-allergy active ingredients comprises the following steps: step 1, extracting and concentrating in groups; step 2, compounding additional ingredients; and step 3, mixing and forming the preparation. The anti-allergy agent containing the compound plant anti-allergy active component is specifically applied to allergic rhinitis nasal spray, postoperative wound repair, pet skin anti-allergy spray, anti-allergy baby clothes treating agent, low-allergy household cleaning agent and air purification spray. And through the synergistic effect of multiple targets and multiple channels, the balanced synergism of the repairing effect and the relieving effect is realized.

The invention discloses application of lactobacillus rhamnosus in preparation of a preparation for relieving allergic rhinitis. The invention provides application of the lactobacillus rhamnosus OF44-15Ph10T or a composition containing the lactobacillus rhamnosus OF44-15Ph10T in preparation of a product with at least one of the following functions: preventing and / or treating allergic rhinitis; the symptoms of allergic rhinitis are improved or relieved; the nasal mucosa injury caused by allergic rhinitis is repaired; intestinal pathogens are inhibited; the intestinal flora balance is regulated; the lactobacillus rhamnosus OF44-15Ph10T provided by the invention provides a new direction for treating allergic rhinitis, can be applied to the fields of food, health care products and medicines, and has a wide industrial prospect.

The invention discloses bifidobacterium longum subsp.infantis capable of relieving and preventing allergic rhinitis and application of the bifidobacterium longum subsp.infantis, and belongs to the technical field of microorganisms and the technical field of medicines. The bifidobacterium longum subsp. Infantis CCFM111 can relieve allergic reaction of allergic mice and relieve and prevent allergic diseases of perennial allergic rhinitis patients, and is specifically shown as follows: (1) weight loss and symptoms caused by allergy of the mice are relieved; lung inflammation infiltration is reduced; the OVA-sIgE level and the total IgE level of serum are reduced; the expression of a proinflammatory factor and an anti-inflammatory factor is regulated. (2) allergy symptoms and medication scores of patients are reduced; the asymptomatic day number proportion of the patient is increased; the serum dermatophagoides farinae and dermatophagoides farinae-sIgE level of patients is reduced; and the expression of cytokines in serum of a patient and nasal irrigation solution is regulated. Therefore, the bifidobacterium longum subsp. Infantis CCFM111 has a huge application prospect in preparation of products for preventing and / or treating allergic rhinitis.

The invention relates to a pharmaceutical composition, in particular to an oral composition for treating allergic rhinitis, which takes magnolia flower and baical skullcap root as monarch drugs, dahurian angelica root, divaricate saposhnikovia root, szechuan lovage rhizome, milkvetch root and Indian buead as ministerial drugs, liquoric root as a guide and the balance as adjuvant drugs. Comprising the following components: 2-3 parts of biond magnolia flower, 2-3 parts of angelica dahurica, 3-5 parts of fructus forsythiae, 3-5 parts of fried burdock, 2-3 parts of divaricate saposhnikovia root, 3-5 parts of dandelion, 3-5 parts of astragalus membranaceus, 3-5 parts of scutellaria baicalensis, 3-5 parts of poria cocos, 3-5 parts of bighead atractylodes rhizome, 10-15 parts of coix seed, 2-3 parts of ligusticum wallichii, 2-3 parts of radix scrophulariae The traditional Chinese medicine preparation for treating wind-heat invading lung and spleen qi weakness type allergic rhinitis has the effects of dispelling wind, clearing lung, dredging nasal orifices and replenishing qi to invigorate the spleen, the symptoms of patients are relieved, and the living quality of vast child patients is improved.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating rhinitis. The traditional Chinese medicine composition comprises platycodon grandiflorum, semen armeniacae amarae, citrus chachiensis hortorum, fructus aurantii, aster, ephedra, radices trichosanthis, thunberg fritillary bulb, liquorice and loquat leaves. The traditional Chinese medicine composition can be used for remarkably relieving sneezing symptoms caused by allergic rhinitis, reducing histamine and specific IgE levels in serum and improving the pathological change degree of nasal mucosa tissues, and has a wide application prospect.

The invention provides a formula for treating rhinitis, and belongs to the technical field of traditional Chinese medicine, the formula for treating rhinitis is prepared from centipeda minima, schizonepeta spike, magnolia flower, cocklebur fruit, radix angelicae, rhizoma atractylodis, rhizoma acori graminei, cavalerie mosla herb, asarum, sal ammoniac, dried alum, musk, borneol and 50-degree white spirit according to specific parts by weight, and the preparation method comprises the following steps: firstly, removing impurities from part of the raw materials, and crushing into powder; when the traditional Chinese medicine is used, the liquid medicine is used for cleaning the nasal cavity and is repeated for 3-5 times, the formula has a good curative effect on diseases such as acute and chronic rhinitis, turbinate hypertrophy, nasal polyp, nasosinusitis and the like, clinical embodiments prove that the symptoms of a chronic rhinitis patient basically disappear after the chronic rhinitis patient is treated for 4 weeks, and the traditional Chinese medicine has a good curative effect. After a patient with nasosinusitis is treated for 6 weeks, inflammation is obviously absorbed, and after a patient with hypertrophy of nasal turbinates is treated for 8 weeks, ventilation basically returns to normal.

The present invention relates to a nasal pharmaceutical composition comprising alcaftadine or a pharmaceutically acceptable salt and optionally one or more pharmaceutically acceptable excipients, methods of treating allergic rhinitis, allergic rhino-conjunctivitis, or symptoms thereof (such as nasal congestion) with the nasal pharmaceutical composition, and methods of preparing it.

The present invention proposes a Chinese medicine composition for treating allergic rhinitis, and a preparation method and application thereof, which belong to the field of pharmaceutical technology. Ag-graphene oxide is adsorbed on in vitro proliferated γδT cells, a Chinese medicine fermentation product obtained by fermentation and extraction of Xanthium sibiricum, Astragalus, Poria, Magnolia officinalis, and Mentha is prepared, berberine and quercetin are prepared into eutectic powder, the three are mixed and added into water, probiotics, carboxymethyl chitosan, poloxamer 407 and poloxamer 188 are added, and mixed evenly to prepare a Chinese medicine composition for treating allergic rhinitis, which has a good effect of improving allergic rhinitis, adopts a method of combining traditional Chinese and Western medicine, reduces inflammatory response, enhances the immune function of patients, improves the clinical symptoms of patients with allergic rhinitis, reduces the long-term recurrence rate, reduces the use of drugs, improves the quality of life, and reduces the risk of developing asthma, and has broad application prospects.

The invention relates to the technical field of rhinitis spray preparation, in particular to a method for preparing allergic rhinitis spray from umbilical cord mesenchymal stem cell exosomes, which comprises the following steps: 1, umbilical cord treatment; 2, culturing umbilical cord mesenchymal stem cells; 3, preparing an umbilical cord mesenchymal stem cell exosome; and 4, preparing the rhinitis spray. The rhinitis spray prepared by the method disclosed by the invention is simpler and more convenient to use. The exosome, the platelet growth factor and other substances in the rhinitis spray well solve the core problems of single curative effect, large side effect, low compliance and the like in the traditional rhinitis treatment, and through the induction and repair functions of the stem cell exosome and the bactericidal ability of the antibacterial peptide, the nasal cavity environment is improved, the anaphylactic reaction is reduced, the nasal mucosa is repaired, and the rhinitis treatment effect is improved. The allergic rhinitis is expected to be fundamentally treated.

The invention provides application of tea extracellular vesicles in preparation of drugs for relieving or treating allergic respiratory diseases, and belongs to the technical field of extracellular vesicles. The invention provides application of tea extracellular vesicles in preparation of drugs for relieving or treating allergic respiratory diseases. The tea extracellular vesicles are proved to be capable of remarkably improving related symptoms of allergic respiratory diseases including allergic rhinitis, have good anti-inflammatory and immunoregulation effects, and have the application potential of being used as natural active ingredients for preparing drugs or nasal delivery preparations for treating the allergic respiratory diseases. Compared with existing hormone drugs, the tea extracellular vesicles have the advantages of being natural in source, high in safety, low in side effect and the like; moreover, the extracellular vesicles have nanoscale particle sizes, good mucous membrane permeability and bioavailability, can improve the curative effect, and are suitable for long-term intervention.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine spray for treating rhinitis and a preparation method thereof.The traditional Chinese medicine spray is prepared from flos magnoliae liliflorae, fructus xanthii, herba ephedrae, fructus forsythiae, flos lonicerae, radix angelicae, herba asari, menthol, herba centipedae and herba menthae. Refining to obtain a fluid extract; and mixing the fluid extract with a penetration enhancer consisting of aminoketone and menthol, a sodium hyaluronate mucous membrane repairing agent, a pH regulator, an isoosmotic adjusting agent and a preservative to prepare spray liquid medicine, and finally performing sterile filtration and filling. Through efficient extraction and synergism of composite auxiliary materials, the permeability and bioavailability of the medicine are remarkably improved, and the symptoms such as nasal obstruction and running nose can be quickly relieved; meanwhile, the anti-inflammatory function and the function of actively repairing the damaged nasal mucosa are achieved, and the recurrence rate is reduced from the source; the pH and osmotic pressure of the preparation are precisely adjusted, the use is comfortable, and the quality is stable and controllable.

The invention belongs to the technical field of microorganisms, and particularly relates to application of bifidobacterium longum in improving immunity and preparing products for preventing, treating and / or assisting in treating rhinitis. The preservation number of the bifidobacterium longum is GDMCC No: 65969, and the bifidobacterium longum can reduce the levels of MDA and NO in serum of mice and improve the activity of SOD and CAT and the content of GSH so as to relieve oxidative stress injury; inflammatory cell infiltration of nasal mucosa is reduced, and lung tissue inflammatory mediator level and inflammation-related gene expression are reduced to inhibit inflammation; th1 / Th2 immune balance is regulated, Th2 type cytokines are reduced, Th1 type cytokines are increased, and the high-dosage effect is close to that of loratadine. The strain has a treatment effect on allergic rhinitis through multiple mechanisms, and a new choice is provided for treatment of the strain.

The invention belongs to the technical field of intelligent medical treatment, and discloses a disease monitoring and diagnosis system for allergic rhinitis and asthma syndromes treated by traditional Chinese medicines. Comprising the steps of collecting a health portrait of a patient and traditional Chinese medicine diagnosis information and performing comprehensive differentiation to obtain a traditional Chinese medicine differentiation result; analyzing the health portrait of the patient, identifying abnormal medical indexes, performing disease diagnosis based on the abnormal medical indexes, and evaluating corresponding comprehensive clinical characterization to form a western medicine diagnosis result; performing cross validation on the traditional Chinese medicine differentiation result and the western medicine diagnosis result to obtain a comprehensive diagnosis result, and dynamically generating a personalized traditional Chinese medicine prescription in combination with the obtained patient personalized factors; environment perception factors are dynamically obtained, and the personalized traditional Chinese medicine prescription is intelligently optimized; the system provides full-process intelligent support for traditional Chinese medicine diagnosis and treatment of the allergic rhinitis and asthma syndrome, so that the diagnosis and treatment quality and the treatment effect are effectively improved, and a more scientific and effective traditional Chinese medicine treatment scheme is provided for patients.

The invention belongs to the technical field of biological medicines, and particularly relates to nasal temperature-sensitive hydrogel with immunoregulation and anti-inflammatory functions as well as a preparation method and application of the nasal temperature-sensitive hydrogel. The preparation method of the nasal temperature-sensitive hydrogel with the immunoregulation and anti-inflammatory functions comprises the following steps: preparation of hydroxybutyl chitosan (HBC), preparation of levodopa-hydroxybutyl chitosan (LHBC), and preparation of CELHBC composite hydrogel. The novel temperature-sensitive hydrogel composite material of the composite hydrogel loaded with the chlorella / exosome can be used for the focus position of allergic rhinitis, and enrichment and retention of active ingredients are achieved; the chlorella is combined with the exosome, so that the inflammatory response of nasal mucosa can be relieved, the damaged nasal mucosa can be repaired, and the immune imbalance of Th1 / Th2 cells can be reversed, thereby improving the treatment effect of allergic rhinitis.

The invention provides a traditional Chinese medicine preparation for treating allergic rhinitis and a preparation method thereof, and relates to the technical field of traditional Chinese medicine pharmacy, the traditional Chinese medicine preparation is prepared from radix asteris, schizonepeta spike, cynanchum paniculatum, perillaseed, spina gleditsiae, cottonrose hibiscus leaf, magnolia flower, semen brassicae, cortex lycii radicis, dendrobe, oroxylum indicum and rhodomyrtus tomentosa; an in-vitro experiment shows that the traditional Chinese medicine preparation can remarkably inhibit the activity of hyaluronidase, also can inhibit the release of beta-HEX in an RBL-2H3 cell degranulation model, reduces the HIS level in a cell supernatant, and effectively improves the morphological abnormality caused by degranulation of RBL-2H3 cells; in-vivo experiments show that the traditional Chinese medicine preparation can significantly reduce behavioral scores of mice suffering from allergic rhinitis, inhibit expression of inflammatory factors TNF-alpha, serum Ig E and OVE-sIg E levels and HA concentration, reduce histopathologic changes caused by allergic rhinitis, effectively repair immune injuries of nasal mucosa of the mice and improve the curative effect of the mice. And a safe and effective new strategy is provided for the treatment of allergic rhinitis.

The invention relates to the technical field of rhinitis medicine preparation, in particular to zirconium-doped cerium oxide nano-enzyme for preparing allergic rhinitis drops and a preparation method of the zirconium-doped cerium oxide nano-enzyme. The preparation method comprises the following steps: step 1, weighing a cerium acetylacetonate (III) hydrate and a zirconium acetylacetonate (IV) hydrate, adding into oleylamine, magnetically stirring and uniformly mixing, and carrying out ultrasonic treatment on the mixture; step 2, putting the mixed solution in the step 1 into a drying oven, heating, preserving heat, and aging to obtain a dark brown colloidal solution; step 3, naturally cooling the colloidal solution to room temperature, adding acetone, centrifuging, discarding supernate, and repeating centrifugal washing for several times; and 4, carrying out vacuum drying on the precipitate obtained in the step 3, and fully grinding to obtain the zirconium-doped cerium oxide nano-enzyme. The prepared zirconium-doped cerium oxide nano-enzyme is applied to preparation of allergic rhinitis drops. The zirconium-doped cerium oxide nano enzyme reduces the inflammatory factor level of the AR mouse and inhibits degranulation of nasal mucosa MCs, so that the pathological state and allergic symptoms of the AR mouse are improved.

There is provided a process for treatment of rhinitis by diode laser ablation of the branches of the posterior nasal nerve. The diode laser delivery device with elongated fiber optic with its fiber tip is inserted through a patient's nostril and has the length, flexibility and a curvature to reach both above and under the patient's middle turbinate for treatment of both branches of the posterior nasal nerves. Skin and tissue temperature is raised to approximately 60-70° C. with the process. A control knob on the laser delivery device moves from a first to a second position to move a camera attached to the laser delivery device. The fiber optic includes a distal fiber tip extending from a malleable sheath connected to the body for delivering light energy to a treatment area.

The invention provides an application of beta-1, 3 / alpha-1, 3-glucan in preparation of a medicine for treating or / and preventing chronic rhinitis. The beta-1, 3 / alpha-1, 3-glucan disclosed by the invention is used for treating or / and preventing chronic rhinitis, is remarkable in symptom improvement, high in safety and wide in application range, can be used for chronic rhinitis patients with different severity degrees, and provides a new choice for long-term management of chronic rhinitis.

The utility model provides an atomizing mask. The atomization cover comprises a cover body, a medicine inlet pipe and a breathing hole, the cover body is worn on the face of the human body, the medicine inlet pipe is connected to the cover body, and the breathing hole is formed in the cover body. The shielding assembly comprises a shielding plate and a plurality of mounting parts, the mounting parts are detachably mounted on the medicine inlet pipe, and the shielding plate is mounted on the mounting parts, shields the mouth of the human body and is configured to abut against the mouth of the human body under the action of the mounting parts. The utility model further provides an atomizer which comprises an atomizing mask and an atomizer body, and the atomizer body is detachably installed at the end, away from the shielding plate, of the medicine inlet pipe. According to the atomization mask, when rhinitis, nasosinusitis, bronchitis, pneumonia and other diseases are treated, liquid medicine is prevented from flowing back into the oral cavity of a user, it is guaranteed that the atomized liquid medicine is sucked into the airway of a patient as much as possible, the treatment effect of the device is improved, and the treatment effect is improved. The liquid medicine can be prevented from entering the oral cavity, so that the use comfort of a user is reduced, and bacterial infection is avoided.

The invention discloses a traditional Chinese medicine composition for treating allergic rhinitis, which is prepared from the following raw materials in parts by weight: 6 to 30 parts of folium mori, 6 to 30 parts of flos chrysanthemi, 1 to 9 parts of radix ginseng, 10 to 30 parts of fructus ziziphi jujubae, 3 to 10 parts of rhizoma zingiberis recens, 3 to 10 parts of liquorice root, 10 to 30 parts of radix astragali seu hedysari, 3 to 12 parts of radix angelicae sinensis, 6 to 15 parts of radix ophiopogonis, 1 to 6 parts of radix puerariae, 3 to 12 parts of radix angelicae dahuricae, 3 to 9 parts of herba menthae and 3 to 10 parts of radix platycodonis. The preparation method of the traditional Chinese medicine composition comprises the following steps: (1) respectively taking the raw materials in parts by weight, and adding water to soak for 1 hour; step 2) adding water and decocting twice, adding 400-900 parts by volume of water each time, boiling and decocting with strong fire for the first time, adding water and boiling with slow fire for the second time, and combining decoctions; and (3) adding pharmaceutically acceptable medicinal auxiliary agents according to a conventional process to prepare clinically acceptable granules, pills, tablets, powder or capsules. The traditional Chinese medicine composition has the effects of resisting allergy, inflammation and bacteria and the like, and can relieve the symptoms of nasal obstruction, running nose, sneezing and the like of allergic rhinitis patients.

The invention relates to the technical field of biological medicines, in particular to application of bifidobacterium longum subsp. Infantis in prevention and / or treatment of allergic rhinitis. Researches find that the Bifidobacterium longum subsp.infantis can improve inflammatory response, relieve symptoms of allergic rhinitis of mice, inhibit immune response caused by the allergic rhinitis, inhibit the inflammatory response caused by the allergic rhinitis and / or repair nasal mucosa injury caused by the allergic rhinitis, and the Bifidobacterium longum subsp.infantis can be used for treating the allergic rhinitis. The compound has a huge application prospect in preparation of products for preventing and / or treating allergic rhinitis.

The invention discloses a preparation method of a traditional Chinese medicine ointment for treating rhinitis, which comprises the following steps: crushing a plurality of traditional Chinese medicine raw materials according to a certain ratio, mixing with a snail liquid extract and an earthworm tissue extract, adding a plurality of enzymes such as cellulase, pectinase and papain for enzymolysis, adding a fermentation substrate, and inoculating a strain for fermentation; the preparation method comprises the following steps: fermenting, decocting for many times by a traditional Chinese medicine decocting machine, concentrating by a decoction process to obtain a thick traditional Chinese medicine paste semi-finished product, cooling the traditional Chinese medicine paste semi-finished product, adding lard paste, beeswax and related auxiliary materials, and carrying out ultraviolet disinfection and canning to obtain a finished product. According to the preparation method of the traditional Chinese medicine ointment for treating rhinitis, through special process treatment, the content of effective components in the medicine is fully increased, the absorption effect of nasal mucosa on the effective components is promoted, and the irritation of the nasal mucosa on the nasal cavity is reduced; meanwhile, by adding auxiliary materials, the absorption effect and the treatment effect after the medicine is smeared on the nasal cavity are further improved.

The invention relates to the technical field of microorganisms, in particular to lactobacillus reuteri for improving allergic rhinitis and nasosinusitis as well as a product and application thereof. The lactobacillus reuteri NHNK-2001 disclosed by the invention is deposited in the China Center for Type Culture Collection, and the preservation number is CCTCC NO: M 2024800. Experiments show that the NHNK-2001 has the functions of inhibiting the growth of nasosinusitis related flora and biofilm formation, flocculating rhinitis pathogenic bacteria, promoting the growth of nasal cavity beneficial bacteria, inhibiting staphylococcus aureus subsp.aureus enterotoxin, degrading histamine, reducing histamine excitation, promoting nasal cavity epithelial cell barrier and reducing nasal cavity epithelial cell inflammation; in addition, a biological membrane formed by the NHNK-2001 thallus can increase the colonization ability to intestinal epithelial cells. The traditional Chinese medicine composition can be used for preparing products for improving allergic rhinitis and nasosinusitis.

The invention discloses a single traditional Chinese medicine powder spray for radically treating allergic rhinitis and preparation and application thereof.The single traditional Chinese medicine powder spray only contains gleditsia sinensis powder, is simple in composition and can temporarily stimulate epithelial cells to secrete normal nasal discharge to block and flush allergens, and nasal cavity flushing is achieved; the traditional Chinese medicine composition can change the local microenvironment of nasal mucosa and cut off the biological process of occurrence and development of allergic rhinitis, and enters the nasal mucosa to serve as a descaling agent, so that an IgE receptor Fc epsilon R1 on a sensitized mast cell membrane is separated from IgE and cannot be combined with allergens, and the mast cell cannot activate and release an allergic medium, so that the allergic rhinitis is radically treated; the preparation process of the single traditional Chinese medicine powder spray is simple and easy to operate, batch production can be realized, and after the saponin powder is processed by the alum, the astringency effect is remarkable, so that the clear water snot symptom of the allergic rhinitis can be improved; the nasal spray is used for treating allergic rhinitis, stimulates secretion of nasal discharge after being sprayed, and is beneficial to cleaning nasal cavities and improving nasal ventilation; the traditional Chinese medicine composition also has a sterilization function and can effectively inhibit bacterial and fungal infection induced by allergic rhinitis.

The application discloses application of volatile oil of Citrus aurantium in preparation of a medicine for preventing and treating allergic rhinitis. The application proposes that the volatile oil of Citrus aurantium can significantly reduce the levels of mast cell factors IL-1beta and TNF-alpha, and can also significantly reduce the levels of inflammatory factors IL-13 and IL-4 in mice, reduce inflammatory cell infiltration, and reduce eosinophilic granulocyte increase and gland hyperplasia. The application proposes that the volatile oil of Citrus aurantium has great potential as a medicinal and edible raw material for treating allergic rhinitis. The application also proposes that the volatile oil of Citrus aurantium can significantly improve symptoms such as sneezing, runny nose, and nasal itching of mice caused by allergic rhinitis, and the symptoms seriously affect the life of patients.

The application provides a galactoside agglutinin 10 (Gal10) crystal and a preparation method and prepared antibody IgY and a pharmaceutical preparation thereof, and belongs to the technical field of medicines. The application uses the galactoside agglutinin 10 crystal as an antigen to prepare an egg yolk neutralizing antibody IgY capable of dissolving the Gal10 crystal, has the effects of improving rhinitis or asthma of a patient, preventing and treating rhinitis and asthma, and is safe, has no side effects, has a long-lasting curative effect, and has no drug resistance, thereby providing a safe, simple, hygienic, effective, economic and personalized treatment mode for prevention and treatment of rhinitis and asthma, and having a high market value.