210 results about "Nasal inflammation" patented technology

The invention discloses bifidobacterium animalis and application thereof in allergic rhinitis products, and belongs to the technical field of microorganisms. The technical problem to be solved is that the existing common allergic rhinitis treatment means cannot meet the requirements of patients on safety, long-acting effect and treatment cycle. The invention provides an animal bifidobacterium subsp. Lactis Def +, and after an effective dose of animal bifidobacterium subsp. Lactis Def + is applied to a subject, the animal bifidobacterium subsp. Lactis Def + is found to be capable of remarkably relieving the allergic rhinitis symptom. Specifically, the symptoms of sneezing, dry nose and rhinocnesmus are reduced; the number of nasal septum mucosa intrinsic layer inflammation infiltration cells and nasal septum mucosa epithelium pathological changes are reduced; the IgA and IgE levels of serum are reduced; the levels of proinflammatory factors IL-4, IL-5 and IL-13 are reduced; the normal spleen index is maintained; the imbalance state of Th1 / Th2 and Th17 / Treg is effectively improved, and the body immunity is improved; a safe and long-acting scheme is provided for allergic rhinitis diseases.

The invention relates to the technical field of rhinitis spray preparation, in particular to a method for preparing allergic rhinitis spray from umbilical cord mesenchymal stem cell exosomes, which comprises the following steps: 1, umbilical cord treatment; 2, culturing umbilical cord mesenchymal stem cells; 3, preparing an umbilical cord mesenchymal stem cell exosome; and 4, preparing the rhinitis spray. The rhinitis spray prepared by the method disclosed by the invention is simpler and more convenient to use. The exosome, the platelet growth factor and other substances in the rhinitis spray well solve the core problems of single curative effect, large side effect, low compliance and the like in the traditional rhinitis treatment, and through the induction and repair functions of the stem cell exosome and the bactericidal ability of the antibacterial peptide, the nasal cavity environment is improved, the anaphylactic reaction is reduced, the nasal mucosa is repaired, and the rhinitis treatment effect is improved. The allergic rhinitis is expected to be fundamentally treated.

The invention provides application of tea extracellular vesicles in preparation of drugs for relieving or treating allergic respiratory diseases, and belongs to the technical field of extracellular vesicles. The invention provides application of tea extracellular vesicles in preparation of drugs for relieving or treating allergic respiratory diseases. The tea extracellular vesicles are proved to be capable of remarkably improving related symptoms of allergic respiratory diseases including allergic rhinitis, have good anti-inflammatory and immunoregulation effects, and have the application potential of being used as natural active ingredients for preparing drugs or nasal delivery preparations for treating the allergic respiratory diseases. Compared with existing hormone drugs, the tea extracellular vesicles have the advantages of being natural in source, high in safety, low in side effect and the like; moreover, the extracellular vesicles have nanoscale particle sizes, good mucous membrane permeability and bioavailability, can improve the curative effect, and are suitable for long-term intervention.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine spray for treating rhinitis and a preparation method thereof.The traditional Chinese medicine spray is prepared from flos magnoliae liliflorae, fructus xanthii, herba ephedrae, fructus forsythiae, flos lonicerae, radix angelicae, herba asari, menthol, herba centipedae and herba menthae. Refining to obtain a fluid extract; and mixing the fluid extract with a penetration enhancer consisting of aminoketone and menthol, a sodium hyaluronate mucous membrane repairing agent, a pH regulator, an isoosmotic adjusting agent and a preservative to prepare spray liquid medicine, and finally performing sterile filtration and filling. Through efficient extraction and synergism of composite auxiliary materials, the permeability and bioavailability of the medicine are remarkably improved, and the symptoms such as nasal obstruction and running nose can be quickly relieved; meanwhile, the anti-inflammatory function and the function of actively repairing the damaged nasal mucosa are achieved, and the recurrence rate is reduced from the source; the pH and osmotic pressure of the preparation are precisely adjusted, the use is comfortable, and the quality is stable and controllable.

The invention belongs to the technical field of microorganisms, and particularly relates to application of bifidobacterium longum in improving immunity and preparing products for preventing, treating and / or assisting in treating rhinitis. The preservation number of the bifidobacterium longum is GDMCC No: 65969, and the bifidobacterium longum can reduce the levels of MDA and NO in serum of mice and improve the activity of SOD and CAT and the content of GSH so as to relieve oxidative stress injury; inflammatory cell infiltration of nasal mucosa is reduced, and lung tissue inflammatory mediator level and inflammation-related gene expression are reduced to inhibit inflammation; th1 / Th2 immune balance is regulated, Th2 type cytokines are reduced, Th1 type cytokines are increased, and the high-dosage effect is close to that of loratadine. The strain has a treatment effect on allergic rhinitis through multiple mechanisms, and a new choice is provided for treatment of the strain.

The invention belongs to the technical field of biological medicines, and particularly relates to nasal temperature-sensitive hydrogel with immunoregulation and anti-inflammatory functions as well as a preparation method and application of the nasal temperature-sensitive hydrogel. The preparation method of the nasal temperature-sensitive hydrogel with the immunoregulation and anti-inflammatory functions comprises the following steps: preparation of hydroxybutyl chitosan (HBC), preparation of levodopa-hydroxybutyl chitosan (LHBC), and preparation of CELHBC composite hydrogel. The novel temperature-sensitive hydrogel composite material of the composite hydrogel loaded with the chlorella / exosome can be used for the focus position of allergic rhinitis, and enrichment and retention of active ingredients are achieved; the chlorella is combined with the exosome, so that the inflammatory response of nasal mucosa can be relieved, the damaged nasal mucosa can be repaired, and the immune imbalance of Th1 / Th2 cells can be reversed, thereby improving the treatment effect of allergic rhinitis.

The invention provides a traditional Chinese medicine preparation for treating allergic rhinitis and a preparation method thereof, and relates to the technical field of traditional Chinese medicine pharmacy, the traditional Chinese medicine preparation is prepared from radix asteris, schizonepeta spike, cynanchum paniculatum, perillaseed, spina gleditsiae, cottonrose hibiscus leaf, magnolia flower, semen brassicae, cortex lycii radicis, dendrobe, oroxylum indicum and rhodomyrtus tomentosa; an in-vitro experiment shows that the traditional Chinese medicine preparation can remarkably inhibit the activity of hyaluronidase, also can inhibit the release of beta-HEX in an RBL-2H3 cell degranulation model, reduces the HIS level in a cell supernatant, and effectively improves the morphological abnormality caused by degranulation of RBL-2H3 cells; in-vivo experiments show that the traditional Chinese medicine preparation can significantly reduce behavioral scores of mice suffering from allergic rhinitis, inhibit expression of inflammatory factors TNF-alpha, serum Ig E and OVE-sIg E levels and HA concentration, reduce histopathologic changes caused by allergic rhinitis, effectively repair immune injuries of nasal mucosa of the mice and improve the curative effect of the mice. And a safe and effective new strategy is provided for the treatment of allergic rhinitis.

The application discloses application of volatile oil of Citrus aurantium in preparation of a medicine for preventing and treating allergic rhinitis. The application proposes that the volatile oil of Citrus aurantium can significantly reduce the levels of mast cell factors IL-1beta and TNF-alpha, and can also significantly reduce the levels of inflammatory factors IL-13 and IL-4 in mice, reduce inflammatory cell infiltration, and reduce eosinophilic granulocyte increase and gland hyperplasia. The application proposes that the volatile oil of Citrus aurantium has great potential as a medicinal and edible raw material for treating allergic rhinitis. The application also proposes that the volatile oil of Citrus aurantium can significantly improve symptoms such as sneezing, runny nose, and nasal itching of mice caused by allergic rhinitis, and the symptoms seriously affect the life of patients.

The application provides a galactoside agglutinin 10 (Gal10) crystal and a preparation method and prepared antibody IgY and a pharmaceutical preparation thereof, and belongs to the technical field of medicines. The application uses the galactoside agglutinin 10 crystal as an antigen to prepare an egg yolk neutralizing antibody IgY capable of dissolving the Gal10 crystal, has the effects of improving rhinitis or asthma of a patient, preventing and treating rhinitis and asthma, and is safe, has no side effects, has a long-lasting curative effect, and has no drug resistance, thereby providing a safe, simple, hygienic, effective, economic and personalized treatment mode for prevention and treatment of rhinitis and asthma, and having a high market value.

The invention discloses an ultraviolet rhinitis therapeutic apparatus, and belongs to the technical field of rhinitis therapeutic apparatuses, the ultraviolet rhinitis therapeutic apparatus comprises a therapeutic apparatus main body, an adjusting assembly is assembled in the therapeutic apparatus main body, and a phototherapy assembly is assembled at the end of the adjusting assembly; by arranging the adjusting assembly and the phototherapy assembly, non-invasive fixation and nasal septum protection are achieved, three areas of the protection sleeve are controlled to bulge through a tough piece to be attached to the inner wall of the nasal cavity in a self-adaptive mode, a traditional nose clip mechanical clamping mode is replaced, and the risk of mucous membrane injury, bleeding or structural deformation caused by direct pressing of the nasal septum is avoided; meanwhile, the movable seat slides along the inner cavity of the tail plug under the driving of the screw rod, the inclined end of the movable seat pushes the inclined surface seat to enable the flexible sheet to expand outwards, the corresponding area of the protective sleeve is driven to bulge, the nasal cavity shape difference of different patients is adapted, the fixing stability is improved, and the foreign body sensation is reduced; the secondary problems of dry mouth, throat discomfort and the like caused by mouth breathing are avoided, and the treatment comfort is guaranteed.

The application relates to the technical field of Chinese medicine preparation, in particular to a medicine composition for treating allergic rhinitis and a preparation method and application thereof, and the preparation method of the medicine composition for treating allergic rhinitis is as follows: step 1, preparing mixed Chinese herbal medicine A and mixed Chinese herbal medicine B; step 2, subjecting the mixed Chinese herbal medicine A to enzymatic treatment to obtain an enzymatic product; step 3, adding a synergistic agent and inoculating compound microorganisms into the enzymatic product, carrying out aerobic fermentation, adding the mixed Chinese herbal medicine B, and then carrying out anaerobic fermentation to obtain the medicine composition for treating allergic rhinitis. The medicine composition prepared in the application can not only effectively relieve the behavior symptoms such as scratching nose, sneezing and running nose of allergic rhinitis mice, inhibit allergic IgE immune response, but also efficiently relieve the symptoms of allergic rhinitis patients, and has good treatment effect.

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a traditional Chinese medicine composition for treating rhinitis, a preparation and a preparation method thereof. The traditional Chinese medicine composition follows the principle of compatibility of monarch, minister, assistant and guide, and is prepared from flos magnoliae, fructus xanthii, centipeda minima, radix angelicae, rhizoma atractylodis, rhizoma acori graminei, radix scutellariae, ligusticum wallichii and mint, the multiple components act on multiple pathogenesis of rhinitis in a synergistic manner, and both symptoms and root causes are treated. The traditional Chinese medicine composition ointment is prepared by mixing the traditional Chinese medicine composition extract, permeation enhancing auxiliary materials and pharmaceutically acceptable auxiliary materials, the permeation enhancing auxiliary materials have a synergistic effect, so that the transdermal permeation efficiency of the medicine can be improved, the medicine can be promoted to quickly and directly reach an inflammation part, the rhinitis related symptoms can be effectively improved, and the traditional Chinese medicine composition ointment is suitable for a wide range of people and has a good application prospect. And a safe and efficient local treatment scheme is provided for a nasal inflammation patient.

The invention discloses a construction method and application of a machin allergic rhinitis animal model, and belongs to the field of disease animal model construction. According to the method, house dust mites are firstly used for sensitization, then 10% hydrogen peroxide and house dust mites are combined for excitation modeling, the 10% hydrogen peroxide destroys nasal mucosa and accelerates occurrence of allergic rhinitis, and the monkeys with allergic rhinitis are obtained after 13 periods of modeling. According to the method, the animal model which is highly similar to human allergic rhinitis in behavior, inflammatory symptom and phenotype is successfully constructed. The model provides guarantee for observing nasal symptoms and rhinitis behaviors of allergic rhinitis, inducing an organism to generate allergy-related immune response, establishing a sensitization basis, simulating a pathogenesis process, researching pathogenesis of allergic rhinitis, screening allergic rhinitis drugs and the like.

This invention provides a medicinal ointment for treating rhinitis based on a traditional Chinese medicine compound and its preparation method, relating to the field of traditional Chinese medicine technology. The medicinal ointment for treating rhinitis based on a traditional Chinese medicine compound comprises the following components in parts by weight: Bupleurum chinense 2-10 parts, Dictamnus dasycarpus root bark 3-7 parts, Magnolia biondii flower 8-12 parts, Xanthium sibiricum fruit 4-10 parts, Centipeda minima 2-6 parts, Liquidambar formosana fruit 6-10 parts, Chrysanthemum indicum flower 6-10 parts, Angelica dahurica root 6-12 parts, Houttuynia cordata flower 8-12 parts, Borneol 1-3 parts, Menthol 1-3 parts, Ligusticum chuanxiong rhizome 5-13 parts, Scutellaria baicalensis root 8-12 parts. The ingredients are: 5-11 parts licorice root, 9-10 parts calamus, 1-5 parts Fritillaria thunbergii, 2-6 parts Gleditsia sinensis thorns, 6-10 parts Saposhnikovia divaricata, 8-12 parts Cynanchum paniculatum, 3-9 parts Kochia scoparia, 1-2 parts artificial musk, 5-8 parts ginger, 3-4 parts myrrh, 4-6 parts Schisandra chinensis, 1-3 parts petrolatum, 1-3 parts beeswax, and 2-3 parts coconut oil. In this invention, myrrh reduces acute inflammatory reactions of the nasal mucosa through its anti-inflammatory effect, while Schisandra chinensis reduces secretions through its astringent effect. The combination of the two can effectively relieve nasal congestion and runny nose symptoms.

The invention relates to the technical field of scheme recommendation, in particular to an allergic rhinitis treatment scheme recommendation method based on artificial intelligence. According to the method, individual feature data of a target individual and individual feature data of historical individuals are merged into a unified data set; determining feature similarity according to the individual feature data of any two individuals in the unified data set; dividing a plurality of reference groups based on the feature similarity, and identifying a target reference group to which the target individual belongs; determining a health state deviation degree based on the clinical manifestation data of the target individual on a plurality of time nodes before intervention, and arranging the health state deviation degree according to time to form health state time sequence data; determining a comprehensive similarity according to the health state time sequence data of the target individual and each historical individual in the target reference group; screening out a high-similarity historical individual set according to the comprehensive similarity; and the candidate treatment schemes are generated based on the historical treatment schemes associated with the set, so that the accuracy of treatment scheme recommendation is improved.

The invention provides a device for treating at least one of rhinitis, congestion, and / or rhinorrhea to thereby reduce or eliminate symptoms associated therewith, including, but not limited to, coughing, sneezing, nasal or throat irritation and itching, and difficulty sleeping. The device includes a shaft, a retractable and expandable end effector, and handle, that, as a whole, provide a high level of precise control and feedback to an operator during a procedure. The shaft includes an electrode array provided along a length thereof configured to deliver energy to specific target sites within the nasal passage and nasal cavity in conjunction with neuromodulation provided by the end effector.

The application discloses CpG-containing oligodeoxynucleotide (ODN) with the function of regulating the body's immune capacity and application thereof. The oligodeoxynucleotide in the application is different from the design concept of traditional A-type CpG ODN in sequence and structure, embodies the complex drug-making rule and overcomes the problem of traditional A-type CPG in drug-making. The oligodeoxynucleotide has excellent activity of regulating the body's immune function in vitro and in vivo, can stimulate the production of I, II and III type interferons, regulates the Th1 type immune response, and inhibits the Th2 type and Th17 type inflammatory response. Therefore, the oligodeoxynucleotide can prevent and treat allergic diseases caused by Th2 type immune response, including allergic rhinitis, atopic dermatitis, asthma, chronic obstructive pulmonary disease, eosinophil and Th17 related diseases, can prevent and treat the infection and spread of respiratory or non-respiratory pathogenic microorganisms including viruses, bacteria, fungi and parasites, can improve the immune level of the elderly and immunodeficient population, can convert "cold tumor" into "hot tumor", improve the effect of cancer immunotherapy, can prevent and treat central nervous system diseases related to immune dysfunction such as Alzheimer's disease, and can be applied to other diseases related to immune dysfunction.

The application discloses an ear-nose-throat department rhinitis and rhinosinusitis nasal cavity flushing device, and belongs to the technical field of medical instruments, which comprises a flushing liquid injection mechanism and an inner-outer cannula breathing mechanism which are used in cooperation, wherein the flushing liquid injection mechanism comprises a liquid storage bag and a first conducting pipe, the first conducting pipe is connected with the liquid storage bag through a liquid delivery pipe, a nasal cavity liquid supply assembly and a nasal cavity foreign matter cleaning assembly are arranged on the first conducting pipe, and the nasal cavity liquid supply assembly is used in cooperation with the liquid delivery pipe; the inner-outer cannula breathing mechanism comprises a second conducting pipe, and a flushing liquid discharge assembly and a positioning assembly are arranged on the second conducting pipe; through the arrangement of the flushing liquid injection mechanism and the inner-outer cannula breathing mechanism, the device can effectively clean the nasal cavity of a patient, meets the demand of different cleaning modes, and has the characteristics of good cleaning effect, simple and convenient use and low manufacturing cost.

The invention belongs to the technical field of medicine, and discloses an artemisia annua pollen allergen sublingual drop as well as a preparation process and application thereof.The preparation is realized through the following core processes: firstly, performing raw material screening and supercritical CO2 degreasing pretreatment on artemisia annua pollen at the full-bloom stage in North China, then performing graded ultralow-temperature freezing and crushing, and performing freeze drying to obtain the artemisia annua pollen allergen sublingual drop. The particle size D90 of the superfine powder is smaller than or equal to 4 microns; then adopting a neutral protease and pectinase composite enzymatic hydrolysis system, and combining 4 DEG C low-temperature pulse ultrasound-assisted treatment to accelerate the dissolution of allergens; carrying out tangential flow grading purification and buffer solution replacement by virtue of 100kDa and 5kDa PES (Polyether Sulfonate) ultrafiltration membranes, and introducing a compound stabilizer; and finally, performing three-stage sterile filtration, and performing encapsulation and preservation. According to the process, through multi-link collaborative optimization, the extraction efficiency and activity stability of allergens are improved, and the prepared sublingual drops have the effects of improving allergic rhinitis, allergic asthma and airway inflammation and also have excellent permeability.

A method for determining the indication for the prevention of persistent AR in the form of problem-based learning in primary school children, consisting of determining the body mass index (BMI, kg / m 2 ) within the range of +1 SDS or more, taking into account the age and sex of the child and IL 1β using the enzyme immunoassay method; with IL 1β equal to or more than 0.029 pg / ml, a child with overweight / obesity is classified as being at high risk for the development of persistent AR, requiring prevention in the form of problem-based learning.

The present invention relates to novel heterocyclic compounds useful in the preparation of medicaments for the treatment of diseases associated with various functions of the histamine 4 receptor.In particular, said drugs are useful for treating inflammatory diseases, allergy, pain, nasal polyps, rhinitis, chronic sinusitis, nasal congestion, nasal itching, asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, atopic dermatitis, psoriasis, eczema, pruritus, itchy skin, urticaria, idiopathic chronic urticaria, scleroderma, conjunctivitis, keratoconjunctivitis, ocular inflammation, dry eye, cardiac dysfunction, arrhythmia, atherosclerosis, multiple sclerosis, inflammatory bowel disease (including colitis, Crohn's disease, ulcerative colitis), inflammatory pain, neuropathic pain, osteoarthritis pain, autoimmune disease, thyroid, immune-mediated (also known as type I) diabetes, lupus, post-surgical adhesions, vestibular disorders and cancer.

This invention provides a quality testing method for nasal drops used to treat allergic rhinitis, belonging to the field of pharmaceutical testing. Specifically, it includes the following steps: S1. Preparing a test solution; S2. Preparing a mixed reference solution; S3. Separately sampling the reference solution and the test solution for analysis; S4. Generating a reference fingerprint chromatogram. This invention can present all different types of components of the medicinal materials on a single chromatogram through a single test, allowing for simultaneous determination of multiple components and achieving comprehensive and accurate quality control of Artemisia annua and Scutellaria baicalensis nasal drops. The quality assessment method provided by this invention has optimized chromatographic conditions and undergone methodological validation, possessing the advantages of method stability, good repeatability, and stable and reliable test results.

1. The name of the design product: nasal congestion reliever. 2. The use of the design product: used as a tool to wear to relieve symptoms of nasal congestion. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view 1.

The invention relates to biodegradable intranasal system for the sustained-release of fluticasone propionate in the intranasal cavity, said system comprising a biodegradable polyester matrix that comprises the fluticasone propionate as the active ingredient to be released in the intranasal cavity, wherein the polyester is selected from the list of poly(L,D-lactic acid) (PLA), poly(caprolactone) (PCL), their copolymers such as PLA-PCL, and mixtures thereof; and a method for preparing said system. The invention also relates to a kit comprising the system of the invention and the means of insertion of the system into the nasal cavity. The invention further relates to fluticasone propionate for use for treating chronic rhinitis or chronic sinusitis, wherein the fluticasone propionate is in a form suitable for administration in the nasal cavity by means of the biodegradable intranasal system of the invention.

The invention provides a traditional Chinese medicine preparation for treating or improving chronic rhinitis, and relates to the field of traditional Chinese medicine pharmacy, and the traditional Chinese medicine preparation comprises patrinia, herba siegesbeckiae, Japanese metaplexis pericarp, oroxylum indicum, adenophora stricta, radix ophiopogonis, radix polygonati officinalis, rhizoma sparganii, fructus kochiae, schizonepeta, cortex dictamni, cortex lycii radicis and salvia chinensis. The traditional Chinese medicine preparation can effectively inhibit LPS-induced excessive inflammatory response of HNEpC, also can significantly reduce VAS score, SNOT-20 score and nasal endoscopic Lund-Kenne score of chronic rhinitis patients, effectively relieves core symptoms such as nasal obstruction, running nose and hypoolfaction, relieves negative effects of diseases on sleep, emotion and daily activities of the patients, relieves nasal mucosa edema, reduces abnormal secretions, and has a good treatment effect on chronic rhinitis. The repair of damaged mucosa is promoted, and the organic lesion of the nasal cavity is effectively improved. The traditional Chinese medicine preparation has high total clinical treatment rate, provides a better and safer new scheme for clinical treatment of chronic rhinitis, and has important clinical application value.

The application belongs to the technical field of medicines, and particularly relates to application of alpha-asarone in preparation of a medicine for treating allergic rhinitis. The application aims at the problems of single drug target, prominent safety hazards and inability to block pathological progress from the root in the existing medicines for treating allergic rhinitis, takes alpha-asarone as an active ingredient, inhibits excessive activation of an inflammation pathway by activating an Nrf2 / HO-1 signal axis, and bidirectionally regulates expression balance of GPX4 and ACSL4 to inhibit ferroptosis and damage of a nasal epithelial barrier. Animal experiments prove that the alpha-asarone can significantly reduce allergic behaviors of model mice, relieve inflammation of nasal mucosa, reverse tissue remodeling, has high safety, and can be prepared into oral or nasal preparations, and provides a new treatment scheme with multiple target points for allergic rhinitis.

The invention discloses a rhinitis pill patch for treating rhinitis and a preparation method thereof. The rhinitis pill patch is prepared from the following raw materials: codonopsis pilosula, honeysuckle, cimicifugae foetidae, astragalus membranaceus, houttuynia cordata, bighead atractylodes rhizome, radix bupleuri, almond, platycodon grandiflorum, fried divaricate saposhnikovia root, paniculate swallowwort root, biond magnolia flower, cassia twig, folium mori, rhizoma zingiberis, white paeony root, radix angelicae, semen lepidii, cocklebur fruit, chrysanthemum, fructus forsythiae, mint, scutellaria baicalensis, pig nail, spina gleditsiae, red paeony root and the like. The preparation method comprises the steps of drying, crushing and pelleting. The rhinitis pill patch is used for relieving symptoms such as nasal obstruction, rhinocnesmus, sneezing and clear nasal discharge, has the functions of tonifying lung and spleen, and ventilating lung and opening orifices, is administrated through the Shenque acupoint, has the clinical effective rate of 98%, is simple, convenient and efficient, is suitable for people of all ages, and is especially suitable for children.

The invention relates to a traditional Chinese medicine technology, and discloses a nasal irrigation traditional Chinese medicine composition for treating allergic rhinitis, a traditional Chinese medicine preparation as well as a preparation method and application thereof. The traditional Chinese medicine composition contains herba epimedii, processed rhizoma atractylodis, pericarpium citri reticulatae viride and halite. The preparation method of the traditional Chinese medicine preparation comprises the following steps: decocting herba epimedii, prepared rhizoma atractylodis, pericarpium citri reticulatae viride and halite with water I at least twice to obtain an extracting solution I, concentrating the extracting solution I, and drying to obtain a dry extract; or the herba epimedii, the processed rhizoma atractylodis and the green tangerine peel are decocted with water II at least twice to obtain an extracting solution II, the extracting solution I is concentrated II to obtain a concentrated solution, and the concentrated solution is mixed with halite. The traditional Chinese medicine composition can effectively absorb medicine components through nasal mucosa through formula compatibility, quickly reaches target organ parts, takes effect quickly and treats both symptoms and root causes.

The invention relates to the technical field of traditional Chinese medicine external preparations, in particular to a traditional Chinese medicine tablet for relieving allergic rhinitis and a preparation method and application thereof. The traditional Chinese medicine tablet consists of asarum, ligusticum wallichii, mentholum, indigo naturalis, centipeda minima, magnolia flower, fried cocklebur fruit, acorus calamus and auxiliary materials. A step-by-step drying method is adopted in the core preparation process, high temperature and low temperature are sequentially carried out, and volatile components are effectively reserved. The traditional Chinese medicine tablet is combined with a mask through a special release valve, medicine components are inhaled through a nasal cavity by using breathing heat and directly act on local parts, symptoms such as rhinocnesmus, sneezing and running nose can be rapidly relieved, whole-body side effects of oral medicine are avoided, and the traditional Chinese medicine tablet has the advantages of being convenient to use, safe and effective.