74 results about "Dosage effect" patented technology

The invention relates to a method for improving the total dosage effect of anti-ionizing radiation of a device. The method comprises the first step of manufacturing a single-layer structure composite material, the second step of manufacturing a multi-layer structure composite material, the third step of measuring transmission coefficients of an electron beam in the composite materials, the fourth step of simulating and calculating theoretical transmission coefficients of the materials based on the Monte Carlo particle transporting method, the fifth step of correcting the electronic transmission coefficients, and the sixth step of carrying out secondary packing on corresponding chips of the device through the composite materials with the best shielding effect. By means of the method, the shielding effect is best, the packing weight is minimal, and the total dosage effect of anti-ionizing radiation of the spacecraft device can be improved.

The invention relates to a method for detecting dioxins in environment. Rat hepatocyte hepatoma H4IIE cells are used as detection means; the cells are treated with adherent culture for 24h; environment sample organic solvent extract or chemicals dissolved by organic solvent is added into the cells; the cells are further cultured for 72 h; a dosage-effect relation standard curve of EROD enzyme vitality induction of 2,3,7,8-TCDD on H4IIE cells is drafted by determining an EROD enzyme activity and using 2,3,7,8-TCDD as a standard compound, so as to further evaluate toxicity effect of dioxin compound in a sample. The invention has advantages of simple operation, low cost, short detection time and high flux, and can be used as rapid screening means for environment sample and suspected dioxin compound.

The invention relates to a method for performing low-dosage radiant biology early warning by utilizing luminous bacteria. According to the method, a dosage-effect relationship between a radiant dosage acceptable by the bacteria and a luminous intensity can be established by utilizing a sensitivity of the luminous bacteria to the low-dosage radiation, and the luminous intensity of the bacteria has positive correlation with the activity of luminous elements such as fluorescein, luciferase and ATP in the bacterial cells. Therefore, through calculation of a luminous intensity suppression ratio of the luminous bacteria, the comprehensive toxicity of the low-dosage radiation for the luminous bacteria can be estimated, and a biology early warning method is established. The method for performing low-dosage radiant biology early warning by utilizing the luminous bacteria has multiple advantages of being convenient, simple and fast to operate, low in cost, high in sensitivity, good in accuracy, low in environment risk and the like.

The invention discloses a method of reducing the content of amylase in hybrid rice and belongs to the technical field of rice genetic breeding. In the method, an original hybrid rice combination: one of a parent of a non-glutinous sterile line / a non-glutinous restorer is modified into a glutinous parent. The hybrid rice is prepared through a hybridization method of a glutinous sterile line / non-glutinous restorer or a non-glutinous sterile line / a glutinous restorer to obtain a hybrid rice variety in which the content of the amylase is lower than that of the original hybrid rice. In the invention, by means of a genetic effect and a genetic dosage effect of a glutinous gene wx, a near-isogenic line combination is reduced in the content of the amylase. In addition, a growth period, a plant and leaf form, panicle traits, floral organ traits, yield traits, disease resistant performance, adaptability and the like of the near-isogenic line combination are free of significant different when the near-isogenic line combination is compared with the original hybrid rice combination. Through quality analysis and taste evaluation, a new hybrid rice variety being appropriate in the content of the amylase and having the taste and the quality which are suitable for people in different region, thereby achieving an object of genetically improving a poor taste and a poor quality due to a high amylase content in the hybrid rice in the prior art.

The invention discloses application of a medicine in resisting Hantaan viruses, namely arbidol. The arbidol has obvious effect of inhibiting the Hantaan viruses in vitro, and the antivirus effect of drug administration before the viruses enter a cell is stronger than that of the drug administration after the viruses enter the cell. The concrete embodiment comprises the following: the drug administration is performed before and after the infection, the positive rate of virus-infected cells and the fluorescence intensity are reduced along with the concentration increase, and the medicine has dosage effect; and the medicine can obviously reduce the positive rate of virus infection, and the mRNA expression of the viruses is reduced. The arbidol has protection and treatment effect on the infection of the Hantaan viruses on a suckling mouse, and the protection effect is stronger than the treatment effect. The drug administration is performed within 24h before the infection; and with the increase of the dosage of the medicine, the death rate of the mouse is reduced, and the average survival days are extended. The drug administration within 24h after the infection can not improve the survival rate of an animal, but can extend the average survival days of the animal. The arbidol has the effect of inhibiting the Hantaan viruses in a body of the animal. The drug administration within 24h before the infection can lighten the pathologic change of tissues (lung, kidney, and brain), and has treatment effect on HFRS. The medicine has prevention effect and also has treatment effect on patients with the hemorrhagic fever with renal syndrome (HFRS) caused by the Hantaan viruses, and no toxic side effect is found.

The invention discloses a novel diterpenoid compound for treating a liver cancer, belongs to the field of medicines, and particularly relates to the novel diterpenoid compound obtained by separation from a dry whole herb of plectranthus excises, and a preparation method and medical application thereof. Based on a first report, the compound can be obtained by extraction, separation and purification from the dry whole herb of the plectranthus excises, and is high in purity. An in-vitro test proves that the compound can effectively inhibit the growth and proliferation of HepG2 cells, the decrease degree and the concentration of the compound (I) present a certain dosage effect trend, and a medicine for treating the liver cancers can be further researched and developed.

The invention discloses an insecticidal composition containing fenoxycarb. The composition comprises the following active components in portion by mass: 1 to 50 portions of the fenoxycarb, 0.05 to 5 portions of abamectin, 0.01 to 1 portion of emamectin benzoate, and 0.1 to 10 portions of profenofos. The invention also discloses application of the insecticidal composition in the aspects of preventing and controlling rice leaf rollers, diamond back moths or beet armyworms. Proved by field pesticide efficacy test, the insecticidal effect of the composition is remarkably higher than corresponding single-dosage effect; and the composition has remarkable synergic function, not only enlarges the insecticidal spectrum, improves the control effect, reduces the control cost and reduces the using amount of a pesticide, but also avoids injury to beneficial insects.

The invention discloses a method for enhancing anti-single particle radiation ability of MOSFET and a MOSFET element, belonging to field effect transistor technology field. In the MOSFET element according to the invention, an acute angle between the side wall of channel in STI region and the active region of the element is defined as the angle of micro-dosage effect caused by the anti-single particle radiation of the element, with value ranged between 78 degrees to 86 degrees. By using the MOSFET element structure according to the invention, the off-state leakage current of the element caused by the single-particle radiation is lower than that the traditional structure by one magnitude. The structure according to the invention has simple process, completely compatible with traditional CMOS process, capable of enhancing the anti-single particle radiation ability of the element and effectively reducing the manufacturing costs simultaneously.