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Okadaic acid, C₄₄H₆₈O₁₃, is a toxin produced by several species of dinoflagellates, and is known to accumulate in both marine sponges and shellfish. One of the primary causes of diarrhetic shellfish poisoning, okadaic acid is a potent inhibitor of specific protein phosphatases and is known to have a variety of negative effects on cells. A polyketide, polyether derivative of a C₃₈ fatty acid, okadaic acid and other members of its family have shined light upon many biological processes both with respect to dinoflagellete polyketide synthesis as well as the role of protein phosphatases in cell growth.
A microporous organic network hollow fiber membrane for efficient extraction of okadaic acid and application thereof
PendingCN122076245ASemi-permeable membranesPreparing sample for investigationHollow fibreFluid phase
This invention discloses a microporous organic network hollow fiber membrane for efficient extraction of okadaic acid and its applications, belonging to the field of marine food safety detection technology. The fiber membrane is prepared by a combination of electrospinning, in-situ growth, and sacrificial template methods. This fiber membrane possesses a hollow fiber structure, high stability, and high extraction efficiency, and can be applied to the efficient extraction of trace amounts of okadaic acid from shellfish samples. Furthermore, by coupling it with high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS / MS), rapid and accurate detection of okadaic acid in shellfish samples can be achieved, demonstrating broad application prospects in the field of aquatic food safety screening.
Owner:MINJIANG NORMAL COLLEGE