269results about "Analysis using electron paramagnetic resonanace" patented technology

The present disclosure provides a method of monitoring a property of a sample, such as a nanoscopic property of the sample. The method comprises the steps of providing a quantum probe having a quantum state and exposing the quantum probe to the sample in a manner such that the property of the sample, in the proximity of the quantum probe, affects quantum coherence of the quantum probe. The method also comprises detecting a rate of quantum decoherence of the quantum probe to monitor the property of the sample. Further the present disclosure provides an apparatus for monitoring a property of a sample.

An electron spin resonance spectrometer includes a bridge to transmit an excitation frequency and to receive a signal frequency; a probe electrically connected to the bridge and comprising: a first conductor in electrical communication with the bridge to transmit the signal frequency to the bridge; a shorting member electrically connected to the first conductor to transmit the excitation frequency to a sample, to produce the signal frequency, and to transmit the signal frequency to the first conductor; and a second conductor electrically connected to the shorting member; and a magnet disposed proximate to the probe.

A sensing probe may be formed of a diamond material comprising one or more spin defects that are configured to emit fluorescent light and are located no more than 50 nm from a sensing surface of the sensing probe. The sensing probe may include an optical outcoupling structure formed by the diamond material and configured to optically guide the fluorescent light toward an output end of the optical outcoupling structure. An optical detector may detect the fluorescent light that is emitted from the spin defects and that exits through the output end of the optical outcoupling structure after being optically guided therethrough. A mounting system may hold the sensing probe and control a distance between the sensing surface of the sensing probe and a surface of a sample while permitting relative motion between the sensing surface and the sample surface.

A miniaturized instrument and method of using electron spin resonance spectrometry for measuring the degradation of lubricating fluids, and the like, that includes continuously passing a sample of such fluid through a resonating RF microwave cavity resonator during the application therethrough of a uniform slowly varying uniform magnetic field that is rapidly modulated and measuring the resulting phase modulation or amplitude modulation thereof to derive an electron spin resonance signal that directly senses the molecular changes in the fluid sample resulting from fluid degradation during operation of the vehicle, such as peroxy radicals in vehicle engine oil and the like.

The invention belongs to the technical field of preparation of quantum dot nanometer materials, and particularly relates to an aqueous phase synthesis method for transition metal Mn doped ZnSe quantum dots. The method comprises the steps of utilizing inorganic metal water-soluble compounds such as zinc nitrate, manganese chloride and the like and carboxylic acid reagents containing sulfhydryl groups as raw materials, and doping transition metal Mn into ZnSe semi-conductor nano-particles in aqueous solution by a nucleation doping method. The method has the advantages of mild reaction conditions, simple and safe operation, and good repetitiveness, eliminates the toxicity caused by the use of heavy metal elements in the prior quantum dots, and successfully synthesizes non-toxic quantum dots emitting yellow visible light. The quantum dots can be taken as a fluorescent marker to be widely applied to cell and tissue imaging due to low toxicity, and can be applied to in vivo imaging research.

A method of and miniaturized apparatus adapted for in-situ measurement of degradation of automotive fluids and the like by micro-electron spin resonance (ESR) spectrometry, wherein the use of a modulated constant magnetic field in an RF resonating variable frequency microwave cavity resonator through which a fluid sample is passed, enables direct detection of molecular changes in such fluid sample resulting from fluid degradation during use.

The invention discloses a method for detecting free radical ration in coal tar. The method comprises the steps of removing moisture in the tar in a high speed centrifuging manner, and preserving a tar sample under low temperature or inert atmosphere; adopting a diamagnetism substance to deliquate DPPH(1,1-Diphenyl-2-picrylhydrazyl radical 2,2-Diphenyl-1-(2,4,6-trinitrophenyl) hydrazyl) to prepare a plurality of DPPH standard samples with different free radical concentrations, carrying out EPR (electron paramagnetic resonance) measurement, carrying out secondary integration on an EPR spectrogram, and recording the corresponding secondary integration area; establishing a standard curve according to the free radical contents of the DPPH standard sample with different free radical concentrations and the secondary integration area of the corresponding EPR spectrogram; and filling the tar sample into a pipe, measuring according to the same EPR measuring condition, carrying out secondary integration on the measured EPR spectrogram, and substituting the secondary integration area into the standard curve so as to obtain the free radical content N. The method provided by the invention can exactly measure free radical content in coal tar, meanwhile, the change of the content of the free radical in the coal tar along with the preservation condition is exactly measured, and the method for detecting ration is provided for the research of the free radical in the coal tar and is very simple and easy.

The invention discloses a measurement method and measurement system of zero-field paramagnetic resonance. According to the measurement method, a paramagnetic resonance spectrum of target electrons ismeasured by utilizing an NV color center in a diamond base material as a probe; a zero-field condition is utilized, adverse effects caused by molecule random orientation can be resisted and the Zeemaneffect generated by an external electric field can be eliminated, so that a needed energy grade structure is directly detected. For example, a space structure of a molecule can be obtained through analyzing an electron-electron fine interaction effect; a local polar environment of the molecule can be obtained through analyzing an electron-nuclear spin superfine interaction effect; a precision displacement device, an optical co-focusing device and an NV color center probe are combined, and the precision displacement device and a co-focusing microscopic device can realize accurate finding and detection of the NV color center; the NV color center is a single-electron probe and has a nano-scale resolution capability, so that a nano-scale detection capability is realized.

ESR imaging probe, system, and method are described. The probe is an ex-situ probe, the system comprises the probe and configured for operating the probe, and the method comprises detecting ESR from outside a resonator of the probe. An exemplary embodiment of a probe according to the invention comprises a cooled dielectric resonator, and one sided gradient coils. An exemplary embodiment of the system comprises source current that is configured to supply to the gradient coils currents of up to 100 A in pulses shorter than 1 μsec.

The invention discloses a surface self-assembly gold nanoprobe with the free radical capture performance and a preparing method and the application thereof. The surface self-assembly gold nanoprobe with the high free radical capture performance is prepared by the following steps: the surface of a gold nano-particle is connected with nitrone free radical probe ligand with the structure of formula II by a connexon of the structure of formula I. The nitrone free radical probe ligand is connected with R3 radical group end. The gold nano-particle is connected with sulfhydryl end of the connexon. In formula Ia and formula Ib, R3 is -OH, -NH2 or -COOH, n is equal to 2-11, and n1 is equal to 1-4. In formula IIc, R1 is -P(O)(OC2H5)2, and R2 is OH, COOH or CH2OH. The surface self-assembly gold nanoprobe with the high free radical capture performance can capture free radicals under low concentration and can be applied as an antioxidant.

The invention provides a method for diagnosing soil pollution condition by using earthworm biomarkers, and belongs to the technical field of soil pollution monitoring and control. In the method, artificially cultured earthworm is used as a standard test animal; four oxidative damage test indexes, namely oxygen free radical, malondialdehyde content, protein carboxyl content and reductive glutathione-oxidative glutathione proportion, are used as the biomarkers for diagnosing soil pollution; clean artificial soil is used as standard soil; and the pollution condition of the tested soil can be quickly and sensitively diagnosed by analyzing the difference of the four oxidative damage indexes in vivo of the earthworm after the earthworm is cultured in the clean artificial soil and the tested soil for certain time. The method can be used for comprehensively diagnosing the soil pollution condition and the health degree, and the method has good sensitivity for trace pollutants in the soil and can be used as a monitoring method for soil pollution early warning. Compared with a chemical analysis method, the method has the characteristics of simple operation and low cost.

The present invention relates to a method and device for non-invasive analysis of the identity and concentration of drugs that are to be administered by injection or infusion.

The instant invention provides in-vivo methods and apparatus for radiation dosimetry assessment in individuals exposed to potentially harmful radiation, based on measurements in-situ of the teeth. The in vivo dosimetry assessment methods and apparatus utilize electron paramagnetic resonance (EPR) techniques; and employ an apparatus comprising an integrated EPR spectrometer system, an ergonomic magnet and a constructed resonator structure. In various aspects, the dosimetry assessment apparatus is configured to be easily portable and withstand potentially adverse mechanical effects of transportation and deployment in the field. The apparatus also is configured with a power supply that is compatible with both conventional AC line voltages and/or other sources of power suitable for field conditions; and may be easily operated by minimally trained technicians to quickly generate a readout of estimated radiation exposure dose.