19results about "Analysis using electron paramagnetic resonanace" patented technology

A light receiving device 13 receives fluorescence emitted by a magnetic resonance member 1 in response to an excitation light and generates a fluorescence sensor signal corresponding to a fluorescence intensity. An arithmetic processing device 31 derives a measurement value based on the fluorescence sensor signal or a detection signal that is obtained from the fluorescence sensor signal. A measurement value, which is measured when the measured field is applied to the magnetic resonance member 1, is defined as a main measurement value. A measurement value, which is measured when the measured field is not applied to the magnetic resonance member 1 and before the main measurement value is measured, is defined as a preceding measurement value. A measurement value, which is measured when the measured field is not applied to the magnetic resonance member and after the main measurement value is measured, is defined as a succeeding measurement value. The arithmetic processing device 31 respectively subtracts the preceding measurement value and the succeeding measurement value from the main measurement value at a predetermined ratio to derive the measurement value of the measured field.

A diamond magneto-optical sensor (100) according to the present invention includes: a diamond (102) having a color center that has an electron spin; a transmission circuit (106) that transmits electromagnetic waves; and an irradiation part that irradiates the diamond (102) with electromagnetic waves transmitted by the transmission circuit (106). The transmission circuit (106) includes an impedance converter (108) for decreasing or increasing, when viewed from the irradiation part, impedance of an electromagnetic wave source (110) that outputs electromagnetic waves. The irradiation part includes a resonator (104).

Described herein are methods and apparatuses to provide accurate measurement of relatively small magnetic fields under ambient conditions while being worn on an ambulatory subject. These methods and apparatuses may allow accurate and reliable detection of biomagnetic fields from organs such as the brain, heart, and muscles, using a magnetometer, and in particular, using an Acoustically Driven Ferromagnetic Resonance (ADFMR) sensor. These methods and apparatuses may incorporate one or more of: a synthetic gradiometer, flexible and / or thin-film / foil shielding, and / or denoising.

The invention relates to a sensor element (1), comprising: a crystal with colour centres, in particular a diamond crystal (2) with NV centres (7). The sensor element (1) has a lens (3) on which the crystal is fixed, wherein the lens (3) has an orientation aid (5) for fixing the crystal to the lens (3) with a predefined orientation, and wherein the lens (3) is transmissive for excitation light (9) for exciting the colour centres, in particular the NV centres (7), and / or is transmissive for fluorescent light (6) which is generated during the excitation of the colour centres, in particular the NV centres (7). The invention also relates to an optical sensor, in particular a magnetometer (12), comprising: a sensor element (1) which is designed as described above, and a magnetic field generator (14) for generating an offset magnetic field (B0) in the region of the crystal, preferably in the region of the diamond crystal (2), wherein the offset magnetic field (B0) is oriented along a magnetic field axis (15).

A magnetic field sensor 1 includes an electrically inert and optically clear substrate 4 that has opposed upper and lower surfaces. A microwave or RF generator element 13 is disposed on the upper side of the substrate where the generator element 13 is configured to be connected to an electrode for connection to a microwave or RF generator. The sensor 1 includes a heterostructure organic light emitting diode (OLED) 2 disposed adjacent the microwave or RF generator element 6, the OLED being configured to be connected to a first electrode and a second electrode.

The present invention achieves quantum measurement with higher time resolution than in the past. This quantum measurement method measures a state change of an object (O) transported by a fluid, by using a plurality of quantum sensors (QSi) disposed along a flow path through which the fluid flows, and the method includes: an introduction step (S11) for introducing the object into the flow path; a measurement step (S12) for measuring the intensity of fluorescence emitted by each quantum sensor when illuminated with excitation light; and an estimation step (S13) for estimating the state of the object from the intensity of the fluorescence at times when a time (ti) required for the introduced object to be transported to each quantum sensor has elapsed.

Disclosed herein are a sensor chip for parallel magnetic sensing of multiple samples, a system for parallel magnetic sensing of multiple samples, and a method for probing multiple samples using an optically addressable solid-state spin system. The sensor chip includes an optically transparent substrate with multiple optically addressable solid-state spin systems arranged in multiple sensing regions in a surface layer below a top surface of the substrate. The sensor chip further includes multiple sample sites, each sample site disposed above a respective sensing region. The sensor chip has a light guide system configured to provide an optical path through the substrate connecting each of the sensing regions.

A fibrosis measurement device that measures fibrosis of a biological tissue non-invasively includes: a sound wave emitter that performs scanning over a surface of a biological tissue as a measurement object to emit sound waves; an electromagnetic wave receiver that receives an electromagnetic wave generated at each location of a biological tissue irradiated with sound waves; a signal extractor that extracts a signal indicating physical property, based on at least one selected from a group including the amplitude, phase, and frequency of an electromagnetic wave received by the electromagnetic wave receiver; an imaging unit that images signals extracted by the signal extractor; and an area comparison unit that compares the area of a portion of the two-dimensional image in which signals indicating a property are displayed, with an area corresponding to a preset threshold of the strength of the signals.

The magnetic field sensor 1 includes a substrate 4 having opposing upper and lower surfaces that are electrically inert and optically transparent. A microwave or RF generator element 13 is disposed on the upper side of the substrate, and the generator element 13 is configured to be connected to an electrode for connection to a microwave or RF generator. The sensor 1 includes a heterostructure organic light-emitting diode (OLED) 2 disposed adjacent to the microwave or RF generator element 6, the heterostructure organic light-emitting diode (OLED) 2 being configured to be connected to a first electrode and a second electrode.

To provide a sensor capable of irradiating an element having an NV center with exciting light and also enhancing light gathering efficiency of fluorescent light emitted by the element.SOLUTION: A sensor comprises: a diamond element 2 which has a color center irradiated with exciting light GL to emit fluorescent light RL; a light source 3 emitting the exciting light GL; an optical sensor 4 receiving the fluorescent light RL; a core 10A propagating the exciting light GL emitted by the light source 3 up to the diamond element 2; and a double-clad fiber 10D having a first clad 10B propagating the fluorescent light RL emitted at the color center arranged outside the core 10A toward the optical sensor 4 and a second clad 10C arranged outside the first clad 10B.SELECTED DRAWING: Figure 1

The present disclosure relates to a carrier device for testing analysis and a forming method thereof, and a testing analysis method. The carrier device for testing analysis comprises a substrate having a through hole penetrating through the substrate along a first direction perpendicular to a top surface of the substrate; and a support layer on the top surface of the substrate for carrying a film layer to be tested, wherein a sample signal generated by the film layer to be tested can pass through the support layer and the through hole, and the substrate can shield the sample signal. The present disclosure simplifies the operation of testing analysis of the film layer to be tested, improves the efficiency of the analysis of the film layer to be tested, and can realize the characterization of the film layer to be tested with sub-nanometer thickness.

The application discloses a scanning tunnel microscope device for realizing electron spin resonance detection and relates to the technical field of microscopes. The scanning tunnel microscope device for realizing electron spin resonance detection comprises a base, a needle tip arranged on the base, the needle tip being configured to run and generate a tunneling current with a sample on the base, a microwave excitation component, the microwave excitation component comprising an antenna and a microwave signal generation and modulation structure, the antenna being arranged on the base, and the microwave signal generation and modulation structure being configured to transmit microwave signals to the antenna and / or the needle tip, and a magnet component arranged on the side of the base away from the needle tip. The microwave radiation direction of the antenna is towards the needle tip. The technical scheme of the application is characterized in that the antenna is arranged on one side of the base, and the microwave signal generation and modulation structure is configured to inject microwave signals to the antenna and / or the needle tip, so as to improve the microwave excitation efficiency and frequency coverage capability and significantly improve the stability of the spin resonance signal and the system adaptability.

A high-frequency magnetic field generator 2 applies microwave to a magnetic resonance member 1. A magnet 3 applies a static magnetic field to the magnetic resonance member 1. An irradiating device 12 irradiates the magnetic resonance member 1 with incident light of a specific wavelength. An FT 4 senses a measurement target magnetic field using a primary coil 4a and applies an application magnetic field corresponding to the sensed measurement target magnetic field to the magnetic resonance member 1 using a secondary coil 4b. A pillar-shaped light guide member 41 guides the incident light to the magnetic resonance member 1, and a pillar-shaped light guide member 42 guides fluorescence that the magnetic resonance member 1 emits from the magnetic resonance member 1. Further, the magnetic resonance member 1 is arranged between an end surface of the light guide member 41 and an end surface of the light guide member 42 in a hollow part of the secondary coil 4b of the FT 4 and in a hollow part of the aforementioned magnet 3.

The application provides a method for capturing, identifying and evaluating environmental persistent organic free radicals. The method for identifying provided by the application adopts a CATT capturing agent, and the structure is shown as formula (1). The CATT capturing agent has good free radical dissociation groups, can capture environmental persistent organic free radicals (EPFRs) in a to-be-detected substance, can release a stable TEMPO nitrogen-oxygen free radical in a 1:1 ratio while capturing the EPFRs, the TEMPO nitrogen-oxygen free radical can be clearly captured by electron paramagnetic resonance (EPR), there is no side reaction, and the free radical capturing adduct generated can be clearly identified by mass spectrometry (MS), that is, EPR and MS information are obtained simultaneously through the CATT capturing agent. Subsequently, ferulic acid with high solubility and few side reactions is screened as an inhibitor, the transfer of free radicals can be realized to inhibit the reaction, and then the contribution evaluation of the target EPFRs is completed.