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5 results about "Ecdysteroid" patented technology
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Ecdysteroids are arthropod steroid hormones that are mainly responsible for molting, development and, to a lesser extent, reproduction; examples of ecdysteroids include ecdysone, ecdysterone, turkesterone and 2-deoxyecdysone. These compounds are synthesized in arthropods from dietary cholesterol upon metabolism by the Halloween family of cytochrome P450s. Phytoecdysteroids also appear in many plants mostly as a protection agents (toxins or antifeedants) against herbivore insects.
Ecdysteroid compounds and their use
PendingCN122127349AOrganic active ingredientsOrganic chemistryPharmaceutical medicineIn vitro proliferation
This invention discloses a jugnitin compound and its applications. The invention provides a jugnitin compound, which is a compound of formula (I), or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof; the compound provided by this invention has one or more effects selected from the group consisting of: (1) inhibitory activity against the in vitro proliferation of tumor cells; (2) in vivo tumor-suppressive effect; (3) in vivo tumor-targeting ability; and (4) good in vivo safety.
Owner:DUALITY BIOTECHNOLOGY (SHANGHAI) CO LTD
Einectin compound and application thereof
The invention discloses an ecteinin compound and an application thereof. The invention provides a compound as shown in a formula (I), or pharmaceutically acceptable salt, ester, stereoisomer, tautomer, polymorphic substance, solvate, isotope label, metabolite or prodrug thereof. The compounds provided by the invention have one or more effects selected from the following groups: (1) the compounds have inhibitory activity on in-vitro proliferation of tumor cells; (2) an in-vivo tumor inhibition effect is achieved; (3) the polymer has in-vivo tumor targeting ability; and (4) the compound has good in-vivo safety.
Owner:DUALITY BIOTECHNOLOGY (SHANGHAI) CO LTD
Polyunsaturated ecdysteroids for use in treatment
PCT designated stageWO2025253149A1Organic active ingredientsSteroidsOxidative stressPharmaceutical drug
Polyunsaturated ecdysteroids for use in treatment The present invention relates to polyunsaturated ecdysteroid compounds for use in hormonal, metabolic, inflammatory and oxidative stress related conditions, as well as pharmaceutical compositions comprising said compounds.
Owner:SZEGEDI TUDOMANYEGYETEM +1
A-ring open-loop euphorbia kansuane triterpenoid as well as preparation method and application thereof
The invention belongs to the technical field of medicines, and particularly relates to an A-ring open-loop euphorbia kansuane triterpenoid compound as well as a preparation method and application thereof. The invention provides two compounds extracted and separated from Dysoxylum gotadhora, the structural formula of the A-ring open-loop euphorbia kansuane triterpenoid is shown in the specification, the A-ring open-loop euphorbia kansuane triterpenoid with the structure has the activity of inhibiting growth of colon cancer cells, and a new strategy is provided for further development of Dysoxylum gotadhora and further research and development of cancer treatment drugs.
Owner:SHANDONG ANALYSIS AND TEST CENTER
Ecdysteroid compounds and their use
This invention discloses a sucrose-like compound and its applications. This invention provides a compound as shown in formula (I), or a pharmaceutically acceptable salt, ester, stereoisomer, tautomer, polymorph, solvate, isotope label, metabolite, or prodrug thereof; the compound provided by this invention has one or more effects selected from the group consisting of: (1) inhibitory activity against the in vitro proliferation of tumor cells; (2) in vivo tumor-suppressive effect; (3) in vivo tumor-targeting ability; and (4) good in vivo safety.
Owner:DUALITY BIOTECHNOLOGY (SHANGHAI) CO LTD