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3 results about "Ecdysteroid" patented technology
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Ecdysteroids are arthropod steroid hormones that are mainly responsible for molting, development and, to a lesser extent, reproduction; examples of ecdysteroids include ecdysone, ecdysterone, turkesterone and 2-deoxyecdysone. These compounds are synthesized in arthropods from dietary cholesterol upon metabolism by the Halloween family of cytochrome P450s. Phytoecdysteroids also appear in many plants mostly as a protection agents (toxins or antifeedants) against herbivore insects.
Ecdysteroid compounds and their use
PendingCN122127349AOrganic active ingredientsOrganic chemistryPharmaceutical medicineIn vitro proliferation
This invention discloses a jugnitin compound and its applications. The invention provides a jugnitin compound, which is a compound of formula (I), or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof; the compound provided by this invention has one or more effects selected from the group consisting of: (1) inhibitory activity against the in vitro proliferation of tumor cells; (2) in vivo tumor-suppressive effect; (3) in vivo tumor-targeting ability; and (4) good in vivo safety.
Owner:DUALITY BIOTECHNOLOGY (SHANGHAI) CO LTD
A-ring open-loop euphorbia kansuane triterpenoid as well as preparation method and application thereof
The invention belongs to the technical field of medicines, and particularly relates to an A-ring open-loop euphorbia kansuane triterpenoid compound as well as a preparation method and application thereof. The invention provides two compounds extracted and separated from Dysoxylum gotadhora, the structural formula of the A-ring open-loop euphorbia kansuane triterpenoid is shown in the specification, the A-ring open-loop euphorbia kansuane triterpenoid with the structure has the activity of inhibiting growth of colon cancer cells, and a new strategy is provided for further development of Dysoxylum gotadhora and further research and development of cancer treatment drugs.
Owner:SHANDONG ANALYSIS AND TEST CENTER
Ecdysteroid compounds and their use
This invention discloses a sucrose-like compound and its applications. This invention provides a compound as shown in formula (I), or a pharmaceutically acceptable salt, ester, stereoisomer, tautomer, polymorph, solvate, isotope label, metabolite, or prodrug thereof; the compound provided by this invention has one or more effects selected from the group consisting of: (1) inhibitory activity against the in vitro proliferation of tumor cells; (2) in vivo tumor-suppressive effect; (3) in vivo tumor-targeting ability; and (4) good in vivo safety.
Owner:DUALITY BIOTECHNOLOGY (SHANGHAI) CO LTD