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1 results about "Zineb" patented technology

Zineb is the chemical compound with the formula {Zn[S₂CN(H)CH₂CH₂N(H)CS₂]}ₙ. Structurally, it is classified as a coordination polymer. This pale yellow solid is used as fungicide. Zineb is also a female name who is originally Arab. Some people claim it to mean a "father's most precious jewel" or "the most important family member". It is sometimes written as Zaynab, Zainab, Zeinab, ...

Application of zineb in the preparation of ERK inhibitors

ActiveCN120860058BProve suppression accuracylow costMAPK/ERK pathwayT cell
This invention belongs to the field of biomedical technology, specifically disclosing the application of mancozeb in the preparation of ERK inhibitors. Through zebrafish embryo models and HEK293T cell experiments, this invention demonstrates that mancozeb can specifically inhibit the MAPK / ERK pathway as an ERK inhibitor, and that at concentrations of 2μM to 8μM, it can induce a three-dimensional spiral notochord malformation in zebrafish embryos similar to that caused by 100μM U0126 treatment, providing a new approach for the preparation of MAPK / ERK pathway inhibitors.
Owner:JINGGANGSHAN UNIVERSITY