11 results about "Vaginal fluid" patented technology

Soluble gp120 (sgp120) is associated to HIV-1-induced immune dysfunction, such as chronic immune activation. However, the detection of sgp120 in biological fluids such as plasma, serum, cervicovaginal fluids, and cerebrospinal fluids is challenging. The present application relates to novel methods and kits for the detection of sgp120 in biological fluids. These methods and kits are based on the use of specific combinations of sgp120-binding molecules recognizing particular domains of sgp120, notably the N-terminal 8-stranded β-sandwich structure, the constant region 1 and 2 (C1-C2) portion, the bridging sheet of the Co-Receptor Binding Site (CoRBS), and / or the CD4-binding domain.

The present invention relates to a self-sampling device for collecting cervico-vaginal fluid, which optimizes self-collection of fluid, makes it easier to handle and ensures aseptic conditions. The device comprises a collecting component, which can be coupled to an actuation rod, which collecting component comprises at least a collecting projection formed by a fin-shaped lamellar body extending longitudinally following a sinusoidal-shaped directrix. Said collecting projection comprises a distal portion that has a double curvature and extends uninterruptedly in a proximal portion, which also has a double curvature, and the portions are curved in opposite directions to each other from an intermediate transition point. The device also comprises an applicator assembly which is provided with a temporary braking mechanism which releasably fixes, as required, the position of the actuation rod inside an applicator sleeve, to prevent the same from accidentally coming out and being contaminated. The device comprises a driving mechanism that inserts and moves the collecting component along the vaginal canal describing a reversible helical movement, which, due to its sinusoidal collecting projections with portions having a double curvature, collects both incoming and outgoing fluid from the vaginal canal.

A collection device for diagnosing vaginal secretions is disclosed. A method of analyzing vaginal fluid includes collecting vaginal fluid in a vaginal fluid collection system and delivering the collected vaginal fluid to a location for analysis. The analysis results may be stored in a secure cloud storage database and may be retrieved therefrom.

Provided are methods of predicting the likelihood of preterm birth (PTB) or early preterm birth (ePTB) for a subject. The methods comprise performing 16S rRNA gene sequencing on vaginal fluid sample DNA to obtain vaginal microbiome 16S rRNA gene sequencing data, and harmonizing the vaginal microbiome 16S rRNA gene sequencing data. The methods further comprise transforming the harmonized vaginal microbiome 16S rRNA gene sequencing data into vaginal microbiome features, inputting the vaginal microbiome features into a predictive model, and predicting, using the predictive model, the likelihood of PTB or ePTB for the subject from whom the vaginal fluid sample was obtained. Computer readable media and systems that find use in practicing the methods of the present disclosure are also provided.

The present application belongs to the technical field of raw materials for female and gender external products, and particularly relates to a bionic vaginal fluid with moisturizing and anti-inflammatory effects and a preparation method and application thereof. The bionic vaginal fluid comprises the following components in parts by weight: polysaccharide of Phaeolepiota aurea 0.1-2 parts and succinyl polysaccharide 0.1-1 part. The present application innovatively uses the combination of polysaccharide of Phaeolepiota aurea and succinyl polysaccharide to prepare the bionic vaginal fluid. The two components cooperate and interact with each other, can play a synergistic effect, and can significantly improve the moisturizing property and anti-inflammatory soothing effect of the bionic vaginal fluid, can provide lubrication and good moisturizing feeling for the vagina, and at the same time help maintain the microecological balance in the vagina and improve the immune resistance of the vagina.

A device includes a shell including a proximal end and a distal end of the shell. The device also includes a plunger within the shell. The plunger can include a flexible stop at a proximal end of the plunger and a distal end. The device can further include an absorptive unit configured to absorb fluid within a vaginal cavity. The absorptive unit can be affixed to the distal end of the plunger. The absorptive unit can include an absorptive element affixed to a frame structure configurable to reversibly transition between a compressed and uncompressed configuration. The absorptive unit can also include a tether coupled to the absorptive unit via the frame structure. The tether can extend through the proximal end of the plunger. Related methods of use are also described.

A device includes a shell including a proximal end and a distal end of the shell. The device also includes a plunger within the shell. The plunger can include a flexible stop at a proximal end of the plunger and a distal end. The device can further include an absorptive unit configured to absorb fluid within a vaginal cavity. The absorptive unit can be affixed to the distal end of the plunger. The absorptive unit can include an absorptive element affixed to a frame structure configurable to reversibly transition between a compressed and uncompressed configuration. The absorptive unit can also include a tether coupled to the absorptive unit via the frame structure. The tether can extend through the proximal end of the plunger. Related methods of use are also described.

A method of analyzing vaginal fluid includes collecting vaginal fluid in a vaginal fluid collecting system and transporting the collected vaginal fluid to a location for analysis. The analysis can be stored in and retrieved from a secure cloud storage data base.

A device includes a shell including a proximal end and a distal end of the shell. The device also includes a plunger within the shell. The plunger can include a flexible stop at a proximal end of the plunger and a distal end. The device can further include an absorptive unit configured to absorb fluid within a vaginal cavity. The absorptive unit can be affixed to the distal end of the plunger. The absorptive unit can include an absorptive element affixed to a frame structure configurable to reversibly transition between a compressed and uncompressed configuration. The absorptive unit can also include a tether coupled to the absorptive unit via the frame structure. The tether can extend through the proximal end of the plunger. Related methods of use are also described.