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38 results about "Neurocognitive" patented technology

Neurocognitive functions are cognitive functions closely linked to the function of particular areas, neural pathways, or cortical networks in the brain substrate layers of neurological matrix at the cellular molecular level. Therefore, their understanding is closely linked to the practice of neuropsychology and cognitive neuroscience, two disciplines that broadly seek to understand how the structure and function of the brain relate to cognition and behaviour.

Upper limb rehabilitation control method and system based on multimode coordination adaptive brain-computer interface

The invention discloses an upper limb rehabilitation control method and system based on a multimode coordination adaptive brain-computer interface, and belongs to the technical field of neural rehabilitation engineering and brain-computer interfaces. The system comprises a brain signal acquisition module, a self-adaptive residual filtering module, a feature extraction module, a predictive control module, an upper limb rehabilitation actuator and a self-adaptive updating module. The core is that a self-adaptive updating module constructs a composite error cost function by fusing kinematics errors of a physical layer and error correlation potentials of a neurocognitive layer, and on the basis of the composite error cost function, a front-end filtering weight and a network weight of a rear-end control model are synchronously adjusted, so that full-link parameter collaborative optimization from signal preprocessing to motion control is realized. According to the method, the framework limitation of single error feedback and independent parameter optimization of a traditional system is broken through, a closed-loop brain-computer interface system which can sense internal and external states and has system-level self-optimization capability is constructed, and the decoding robustness, the control precision and the practicability under long-term use are effectively improved.
Owner:UNIV FOR SCI & TECH ZHENGZHOU

End-to-end automatic driving system based on electroencephalogram intention modeling and machine mental reasoning

The invention relates to the technical field of automatic driving, and discloses an end-to-end automatic driving system based on electroencephalogram intention modeling and machine mental reasoning, and the system comprises an electroencephalogram signal collection module which is used for collecting an electroencephalogram signal of a driver in real time and carrying out the preprocessing of the electroencephalogram signal; the electroencephalogram intention decoding module is used for extracting driving intention features and outputting structured intention vectors; the machine mental reasoning module is used for fusing the intention vector, the vehicle state and the environment perception information, deducing the mental state of the driver and outputting a mental state vector; and the end-to-end automatic driving control module is used for performing multi-modal fusion on the intention vector, the mental state vector, the environment perception characteristics and the vehicle dynamic state to generate a continuous vehicle control instruction. According to the method, the neurocognitive activity of the driver can be converted into decision-making elements which can be understood and utilized by a machine in real time, so that man-machine cognitive alignment and closed-loop cooperative control are realized.
Owner:CHINA AUTOMOTIVE ENG RES INST +1

Music teaching system based on artificial intelligence

The invention discloses a music teaching system based on artificial intelligence, and particularly relates to the technical field of artificial intelligence, and the music teaching system comprises a neurocognitive adaptation module, a music DNA map construction module, a cognitive load monitoring module, an anti-AI dependence adjustment module and a multi-source data fusion unit. According to the music teaching system based on artificial intelligence, a dynamically evolved personalized teaching model is constructed through multi-modal data fusion and real-time analysis driven by artificial intelligence. The neurocognitive adaptation module is combined with electroencephalogram feature analysis and physiological signal monitoring to accurately capture cognitive preferences and ability bottlenecks of the learner; the music DNA map is based on the quantum enhancement modeling technology, the skill development trajectory is continuously updated and predicted, the AI teaching strategy can realize millisecond-level dynamic adjustment according to the neural feedback and behavior data of the learner, the skill mastering efficiency and the knowledge retention rate are remarkably improved, and the limitation of staticization and simplification of a traditional teaching system is broken through.
Owner:PINGLIANG VOCATIONAL & TECH COLLEGE (PINGLIANG SPORTS SCHOOL)

System and method for laboratory diagnosis and treatment targeting in idiopathic psychosis via psychosis biotypes

A method and system for diagnosing an idiopathic psychosis patient and improving treatment targeting for that patient. Cognitive performance is measured on the patient. Pro- and anti-saccade signals are measured on the patient. Motor inhibition is measured on the patient. EEG signals are measured on the patient. Principal components analysis is applied to the measured signals and scales to determine the most significant features. The patient is evaluating on at least 11 dimensions of neuro-cognitive performance. A trained numerical taxonomy approach is used to classify the patient as belonging to a B-SNP psychosis Biotype and the patient's condition is categorized based on the classified Biotype. The B-SNIP psychosis Biotype is used to implement targeted treatment for an individual patient. The diagnostic algorithm is continuously re-trained using new cases and new laboratory tests to improve precision of B-SNIP psychosis Biotypes diagnosis and the accuracy of selecting treatments for individual patients.
Owner:UNIVERSITY OF GEORGIA RESEARCH FOUNDATION INC +4

Spraying and lamplight integrated device and lamplight atmosphere effect generation method

The invention relates to the technical field of light atmosphere, and discloses a light atmosphere effect generation method, which comprises the following steps: generating an initial wave function according to an intensity field, deducing on the basis of a potential energy field to obtain a first wave function, performing intensity calculation and phase extraction from the first wave function to obtain a second wave function, updating the direction field based on the second wave function to obtain an updated direction field and an enhanced optical flow field; three core advantages of light atmosphere generation are realized, firstly, deep coupling of quantum optics and neurocognition is realized, real response of human eyes is simulated through a phase-sensitive light response model, and light atmosphere distribution is enabled to conform to quantum propagation rules and human visual cognition characteristics in combination with a cognition attention focusing mechanism of a DQN model; and 2, a dynamic self-adaptive mechanism runs through the whole process, and a light current coefficient and object motion data are adjusted in real time through the pupil diameter to feed back a new light flow field so as to ensure that the environment change can be quickly responded.
Owner:GUANGZHOU FENGYI STAGE LIGHTING EQUIP CO LTD

Multifunctional portable device and system for physical and neurocognitive training

The present invention relates to a multifunctional portable device and system for physical and neurocognitive training. The device comprises a casing consisting of a casing body and a casing lid. The casing houses therein a visual interface, a controller with wireless connection, a battery, a vibrating motor, one or more sensors configured to measure at least one parameter selected from distance, acceleration, angular velocity in different axes, heart rate, blood oxygen level, force and weight. The multifunctional portable device comprises assembly elements located on the casing that are configured to allow a user to perform physical training and allow one or more users to perform neurocognitive training.
Owner:UNIV ADOLFO IBANEZ

Method for managing disorders associated with circadian rhythm disorder

PendingCN121175054AOrganic active ingredientsNervous disorderSecondary PreventionsNutrition
A method of managing a disorder associated with a circadian rhythm disorder in a subject by administering to the subject an effective amount of a beta glucan oligosaccharide and / or an arabinose oligosaccharide. More specifically, the management includes treating a symptom associated with a circadian rhythm disorder, primary preventing a symptom associated with a circadian rhythm disorder, secondary preventing a symptom associated with a circadian rhythm disorder, and / or delaying progression of a symptom associated with a circadian rhythm disorder. The symptoms to be managed include symptoms related to sleep, symptoms related to emotion, symptoms related to cognitive function decline and neurocognitive decline, and the like. In particular methods herein, the risk of developing a symptom associated with a circadian rhythm disorder in the subject is assessed prior to administration of the beta glucan oligosaccharide and / or arabinose oligosaccharide. Also provided are medicaments, nutritional formulations, nutritional supplements and pharmaceutical compositions comprising an effective amount of beta glucan oligosaccharides and / or arabinose oligosaccharides for use in such treatment, prevention and delay.
Owner:WANEN BIO

A kit for predicting the risk of occurrence of a delay in neurocognitive recovery and uses thereof

The application discloses a kit for predicting the risk of neurocognitive recovery delay and application thereof. The kit comprises reagents for detecting the expression level of lipid metabolism markers in a sample, wherein the lipid metabolism markers comprise at least one of TG (58:7 / 22:5), TG (54:2 / 18:1), PE (O-16:0 / 18:1) and CL (72:3 / 18:2). The application finds through experiments that, compared with non-neurocognitive recovery delay (non-dNCR) patients, the expression level of TG (58:7 / 22:5) and TG (54:2 / 18:1) in dNCR patients is down-regulated, and the expression level of PE (O-16:0 / 18:1) and CL (72:3 / 18:2) in dNCR patients is up-regulated. By detecting the expression level of the aforementioned lipid metabolism markers, the risk of dNCR of a patient can be confirmed before and / or in an early stage after surgery, early intervention and treatment are facilitated, and postoperative repair is promoted.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Measuring system for measuring hand-eye reaction capability

The invention relates to a measuring system for repeatedly measuring reaction time curves in complex neurocognitive tasks. The measuring system comprises a measuring body, at least one force source, at least one holding device, at least one triggering unit, at least one first sensor unit for acceleration measurement, at least one second sensor unit, at least one interface for data transmission and at least one data processing unit. The invention likewise relates to a method for quantifying reaction times, in which a measuring system is used. Thereby, human influences in the implementation of the test are avoided as far as possible. By shifting the data processing, the measuring system can construct a growing and anonymous data base independently, which improves the accuracy through its continuously growing data volume. Thereby, conclusions about potentially risky changes in the reaction time can also be achieved up to the indication and / or recognition of neurodegenerative diseases.
Owner:SANIVA DIAGNOSTICS GMBH

Device for profiling, assessment and controlled application of psychometric, psychological, psychodiagnostic, neurocognitive, neurobehavioural, professional, occupational, vocational and educational tests

PCT designated stageWO2026044370A1Psychotechnic devicesSensorsDistractionEngineering
The present device aims to create ideal conditions for performing human profiling, assessment and testing processes, in a controlled, simple, accurate, inclusive and distraction-free manner. In order to achieve this aim, the device offers a minimalist, dedicated interface, having a simplified physical keypad that can have various formats depending on the application. During the performance of the test, built-in or peripheral cameras and sensors can collect additional information relating to the attentional, cognitive, physiological and emotional state of the user. This data is processed by the device in order to generate information that can be combined with the other results to produce an even more in-depth assessment of the subject being tested. The entire assessment process can take place in online mode, allowing immediate synchronization with a server, or in offline mode, allowing subsequent synchronization with a server or the downloading of the data directly to a computer. In both cases, an administrative dashboard accessible via the device or via the web can be used to download or create new tests, update the existing tests, register users, view the results and manage the entire assessment process. Finally, the possibility of presenting the test stimuli by means of virtual reality goggles further increases the potential uses and versatility of the equipment.
Owner:BITTAR PARTICIPACOES E NEGOCIOS SA

An enterprise capability evaluation method based on neural cognitive diagnosis technology

The application discloses an enterprise capability evaluation method based on neural cognitive diagnosis technology, comprising the following steps: 1, dividing the technology achievement data into fields, and constructing negative samples of interactive data; 2, constructing a basic neural cognitive diagnosis enterprise capability evaluation learning module, obtaining embedded vector representations such as field mastery, technology achievement difficulty and discrimination, and performing representation learning on the target embedded vector; meanwhile, the embedded vector is interacted, and self-adaptive learning is performed after two full connection layers; 3, constructing a partial order sorting learning module, and constructing a BPR loss after a partial order learning module, an expected capability change module and an enterprise-technology achievement interactive result constraint design module; 4, using cross-entropy loss and contrast loss to optimize the self-adaptive diagnosis network of the whole model. The application utilizes enterprise-technology achievement interactive data to perform self-adaptive diagnosis on technology enterprise capability evaluation, thereby providing an effective method for enterprise capability evaluation in different fields.
Owner:ANHUI UNIV

A teaching evaluation sentiment analysis method fusing cognitive transfer

The present application relates to a kind of fusion cognitive transfer teaching evaluation sentiment analysis method, belong to the field of educational informationization.The method includes: the data collected is cleaned and preprocessed;Unstructured teaching evaluation text is carried out word embedding using BERT language model, it is input in bidirectional GRU network and learns, the context hidden memory information of output text;Student historical practice record is modeled using neural cognitive diagnosis model, and the personalized cognitive ability vector of student is obtained as prior knowledge representation;The text hidden memory information extracted is fused into cognitive transfer matrix with prior knowledge information, and prior knowledge is transferred into text memory by attention mechanism, and the real emotional characteristics contained in text are enhanced.The present application can accurately classify the sentiment of teaching evaluation text carrying conflictive emotional characteristics, solve the problem that sentiment is misclassified due to the existence of conflictive emotional characteristics in teaching evaluation.
Owner:CHONGQING UNIV OF POSTS & TELECOMM

Product ergonomics design method based on AI

The invention discloses an AI-based product ergonomics design method, and relates to the technical field of product ergonomics, and the method comprises the steps: collecting a real-time multi-modal data stream of a user, and carrying out the preprocessing; carrying out weighted fusion and feature extraction on the preprocessed multi-modal data flow by utilizing a multi-source data fusion network of an attention mechanism, and generating a current ergonomic state evaluation result of the user; when the current ergonomic state evaluation result of the user indicates that the risk exists, calling a personalized skeletal muscle digital twinborn model of the user, calculating the real-time stress distribution of the internal tissue of the user in combination with the multi-modal data stream, and analyzing the electroencephalogram signal in the multi-modal data stream to judge the neural adaptability level; and generating an intelligent collaborative intervention decision instruction. According to the method, biomechanical simulation and neurocognition evaluation are deeply fused, so that the spanning from macroscopic attitude regulation to microscopic stress optimization and from one-way intervention to adaptive learning is realized, and the accuracy, humanization and sustainable evolution ability of ergonomic design are improved.
Owner:CHINA NAT INST OF STANDARDIZATION

AI-based product ergonomics design method

This invention discloses an AI-based product ergonomic design method, belonging to the field of product ergonomics technology. The method includes: collecting and preprocessing real-time multimodal data streams from users; using a multi-source data fusion network with an attention mechanism to perform weighted fusion and feature extraction on the preprocessed multimodal data streams to generate an assessment result of the user's current ergonomic state; when the assessment result indicates a risk, calling the user's personalized skeletal muscle digital twin model and combining it with the multimodal data stream to calculate the real-time stress distribution of the user's internal tissues, and analyzing the EEG signals in the multimodal data stream to determine the level of neural adaptability, generating intelligent collaborative intervention decision instructions. This invention, through the deep integration of biomechanical simulation and neurocognitive assessment, achieves a leap from macroscopic posture control to microscopic stress optimization, and from unidirectional intervention to adaptive learning, improving the accuracy, humanization, and continuous evolution capabilities of ergonomic design.
Owner:CHINA NAT INST OF STANDARDIZATION

Use of diacylglycerol in preparation of a drug for improving nutritional composition of breast milk and promoting neural development of offspring

PendingCN122163593ANervous disorderMetabolism disorderNutritionEther lipid
The application discloses application of diacylglycerol in preparation of medicines for improving nutritional composition of breast milk and promoting neural development of offspring, and belongs to the technical field of medicines. The complete technical chain of "maternal intake of DAG, remolding of breast milk lipids (enrichment of long-chain polyunsaturated ether lipids), activation of 2-AG signal pathways of offspring, and promotion of neural cognitive development" is provided, which provides a scientific basis for development of new maternal nutrition products, and has extremely high clinical application value and industrialization prospect.
Owner:GUANGDONG PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE HAINAN HOSPITAL

Reproducible identification of acute-stage mild traumatic brain injury using machine learning and connectomics

PendingUS20250217977A1Image enhancementImage analysisSequelaConnectomics
A system and method operates for diagnosis of mild traumatic brain injury (mTBI) to prevent sequelae and improve neurocognitive outcomes. The system may have a processor that receives, from a magnetic resonance imaging machine, data corresponding to magnetic resonance imaging images. By using a machine learning classifier of the processor, such as a Bayesian machine learning classifier, the processor identifies mild traumatic brain injury in a person through cortico-cortical connectome mapping from magnetic resonance imaging. The processor can also generate a human readable screen display indicative of the identified mild traumatic brain injury.
Owner:UNIV OF SOUTHERN CALIFORNIA

Physical Stimulation-Driven Lymphatic Circulation and Cognitive Enhancement Methods and Systems

This invention relates to the field of cognitive data processing technology, and more particularly to a method and system for physical stimulation-driven lymphatic circulation and cognitive enhancement. The system includes a physical stimulation frequency impact assessment module, a stimulation mechanical vibration analysis module, a lymphatic circulation vibration calibration module, and a stimulation frequency drive adjustment module. It utilizes pressure and temperature sensors to monitor the corresponding physical stimulation pressure and the surface temperature of the stimulated skin in real time, performing stimulation frequency impact assessment and stimulation mechanical vibration analysis to generate a physical stimulation mechanical vibration effect. It also acquires lymphatic fluid flow velocity and EEG neural activity signals, performing neurocognitive level analysis and vibration response calibration. Simultaneously, it performs lymphatic circulation cognitive regression analysis and stimulation frequency drive adjustment to generate a physical stimulation frequency drive adjustment scheme corresponding to lymphatic circulation cognitive enhancement. This invention can accurately analyze the correlation between physical stimulation and lymphatic circulation and cognitive enhancement.
Owner:SHANGHAI MENTAL HEALTH CENT (SHANGHAI PSYCHOLOGICAL COUNSELLING TRAINING CENT)

Roles of modulators of intersectin-CDC42 signaling in alzheimer's disease

PendingUS20260091009A1Nervous disorderAmide active ingredientsCdc42 signalingHydrazone
Methods of treating Alzheimer's disease and other neurodegenerative and / or neurocognitive and / or neurodevelopmental diseases are described. The methods comprise the administration of compounds that modulate an activity of cell division control protein 42 (Cdc42), such as the interaction between Cdc42 and intersectin (ITSN). Exemplary modulator compounds include thioureas, disulfonamides of fused aromatic systems (e.g., benzofuran), and acyl hydrazones, among others. Some of the modulator compounds act as activators of Cdc42, while others act as inhibitors. In some cases, the modulator compound has dual functionality and the ability of the modulator compound to act as an inhibitor or activator depends on whether or not Cdc42 is already activated in a particular disease stage or biological environment by an upstream activating signal of Cdc42.
Owner:LU QUN

Systems, methods, and computer-acessible medium for providing predictors of low risk for delirium during anesthesia emergence

Exemplary system, method and computer-accessible medium can be provided to monitor electroencephalography (EEG) data from the patient during an emergence from a general anesthesia previously provided to the patient, and predicting neurocognitive impairment based on a slope of EEG power. The neurocognitive impairment predicted can be delirium or it may be a predictor of long-term impariment such as Alzheimers. Further, the system and method can be used to direct a medical intervention based on the predicted neurocognitive impairment.
Owner:THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK

Cognitive ability prediction method and system, electronic equipment and readable storage medium

The invention discloses a cognitive ability prediction method and system, electronic equipment and a readable storage medium. The method comprises the following steps: extracting frequency domain features of electroencephalogram signals; extracting functional connection characteristics of the electroencephalogram signals; constructing a neurocognitive double-effect hypothesis equation based on the frequency domain features and the functional connection features; calculating a cognitive ability value according to a neurocognitive double-effect hypothesis equation; and performing cognitive ability prediction based on the cognitive ability value to obtain a cognitive ability prediction result. According to the method, the overall neural calculation efficiency can be quantified by integrating neural energy consumption, network connection lines and task difficulty, and the accuracy of cognitive ability prediction can be improved.
Owner:NAT UNIV OF DEFENSE TECH

Creation and cerification of memory-based experiences and generation of personality / capability profiles therefrom

System and method in field of human resource management, leadership development, executive succession planning, organizational culture modeling, recruitment, talent management, and individual capability profiling. System integrates memory certification protocols with neurocognitive and emotional profiling, creating a multi-dimensional platform for individual and organizational development through verified autobiographical, observational, and interpersonal memory artifacts. Provides a legally defensible foundation for employment, promotion, and succession decisions, additionally enabling potential use in broader legal contexts such as law enforcement, insurance underwriting, and compliance audits.
Owner:REMINISEQUENCE INC

Autonomous device for evaluating the neurocognitive and physiological functions related to motion sickness and simulator sickness

The invention relates to a portable, autonomous device for evaluating sensory and cognitive problems, characterised in that it comprises: - a processor configured to acquire and analyse real-time data; - an ECG module for capturing the user's heart rate variability (HRV) in response to sensory and cognitive stimuli; - an inertial measurement unit (IMU) comprising an accelerometer and a gyroscope, configured to detect and record the movements and posture of the user; - a capacitive touch screen for interaction with the user for carrying out standardised cognitive tests; - an integrated memory for storing the captured data and the programs; - a wireless connectivity module for transmitting the data to an external device; and in that the device is configured to perform, in real time, at least one evaluation of the impact of the disruptive sensory stimuli, including motion sickness and virtual-reality sickness, in uncontrolled environments.
Owner:NEURAL BALANCE INNOVATION

Smartstealth agent for secure cognitive user profiling in cybersecurity systems

ActiveUS12719936B1Cognitive userPersonalization
The invention relates to cybersecurity systems leveraging neuro-cognitive user profiling for real-time anomaly detection. It introduces a stealth-mode endpoint agent designed to collect encrypted micro-interaction telemetry—including cursor dynamics, typing cadence, window focus ETC—without significantly impacting system performance or requiring elevated privileges. Captured signals are transmitted to a centralized AI engine that constructs individualized behavioral baselines and detects deviations using adaptive learning algorithms. The system supports both agent-based and agentless deployments, enabling hybrid use in cloud, on-premise, and BYOD environments. Privacy compliance is addressed through local preprocessing and encryption, aligned with frameworks such as GDPR and HIPAA. The invention is designed to improve behavioral anomaly detection while minimizing operational impact and supporting compatibility across enterprise environments.
Owner:MARILI OR

A neural cognitive heuristic-based dual-system game visual language navigation method and device

The application discloses a dual-system game visual language navigation method and device based on neural cognitive inspiration, which comprises the following steps: acquiring visual feature information and language feature information, extracting visual feature embedding and text feature embedding, and then performing modal alignment and feature fusion to obtain a current state; inputting a state, an action and a global hidden state of a previous moment into a world model based on a gated recurrent unit to generate a current global hidden state; based on the current state and the current global hidden state, based on a multi-brain region collaborative mechanism, generating initial activation tendencies of a goal-oriented system and a habit system by using a prefrontal cortex and a sensory motor cortex, calculating dynamic interest functions of the goal-oriented system and the habit system by using a precingulate gyrus, a thalamus and a premotor cortex, arbitrating and selecting an execution system according to the initial activation tendencies and the dynamic interest functions of the goal-oriented system and the habit system, generating a current execution action by using the execution system, and feeding back and adjusting.
Owner:NANJING UNIV OF INFORMATION SCI & TECH

Test method and apparatus for evaluating cognitive function decline

Provided are a test method and apparatus for evaluating cognitive function decline. The test method for evaluating cognitive function decline includes performing a testing stage of testing how many missions presented for each of a plurality of test items a user performs, and calculating a test score for each of the plurality of test items, performing a category classifying stage of classifying at least one test item from among the plurality of test items as one neurocognitive category from among a plurality of neurocognitive categories, and performing an evaluating stage of evaluating whether there is cognitive function decline in the one neurocognitive category, based on a test score of the at least one test item classified as the one neurocognitive category.
Owner:EMOCOG CO LTD

Compositions and methods relating to use of agonists of ALPHA5-containing GABAA receptors

The invention provides methods and related compositions for preventing neurocognitive decline associated with chronic stress, age, and neurodegenerative diseases. The methods described here are based upon the use of alpha5-GABAA receptor agonists to slow or prevent deleterious morphological changes in dendrites of the hippocampus and prefrontal cortex, which eventually manifest in functional decline and the neurocognitive deficits.
Owner:CENT FOR ADDICTION & MENTAL HEALTH

Audio-based interactive simultaneous exercise and cognitive control training for improving cognitive networks subserving neuropsychiatric and neurocognitive conditions

PendingUS20260041346A1Physical therapies and activitiesMedical data miningStatistical databaseBrain circuit
A method and system utilize unexpected combinations of cognitive exercises to provide routines performed simultaneously with aerobic exercise to address cognitive impairments. Cognitive exercises comprise specific steps in order to interact with a specific cognitive domain. All stimuli may be aural. Specific combinations of cognitive exercises are created to engage selected brain circuits and are correlated to specific cognitive impairments. The method may remediate selected cognitive impairments and strengthen cognitive abilities. The user responds to instructions for each exercise and performs each exercise in a specific order for a specific duration of time and through a specific number of sets. A processor performs a program comprising the routines and evaluates performance of a user. A program may be customized for an individual user. An individual user's data is processed to evaluate progress. Large libraries of data for multiple users may be processed to provide statistical databases.
Owner:MCEWEN SARAH +1

Methods, systems, and computer readable media for awake neurosurgical planning and testing

A method for awake neurosurgical planning and testing includes presenting, to a subject undergoing an awake neurosurgical procedure, during the awake neurosurgical procedure, and using a head mountable device, tests for evaluating neurocognitive or motor functions controlled by a region of the subject's brain being evaluated for tumor resection. The method further includes receiving, by a test controller module, responses of the subject to the tests. The method further includes automatically selecting or generating, by the test controller module, and based on the responses, further tests to present to the subject during the awake neurosurgical procedure. The method further includes presenting, via the head mountable device and to the subject, the tests selected or generated based on the subject's responses.
Owner:THE UNIV OF NORTH CAROLINA AT CHAPEL HILL

Kit for predicting occurrence risk of neurocognitive recovery delay and application thereof

The invention discloses a kit for predicting the occurrence risk of neurocognitive recovery delay and application of the kit. The kit comprises a reagent for detecting the expression level of a lipid metabolism marker in a sample to be detected, wherein the lipid metabolism marker comprises at least one of TG (58: 7 / 22: 5), TG (54: 2 / 18: 1), PE (O-16: 0 / 18: 1) and CL (72: 3 / 18: 2). It is found through experiments that compared with non-dNCR patients, the expression levels of TG (58: 7 / 22: 5) and TG (54: 2 / 18: 1) in the dNCR patients are reduced, the expression levels of PE (O-16: 0 / 18: 1) and CL (72: 3 / 18: 2) in the dNCR patients are increased, the risk of dNCR occurrence of the patients can be confirmed in the early stage before and / or after an operation by detecting the expression levels of the lipid metabolism markers, early intervention and treatment are facilitated, and the risk of dNCR occurrence of the patients is reduced. The postoperative repair is promoted.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE