Topical pharmaceutical composition for preventing and treating bacterial vaginosis

Abstract

The invention provides a topical pharmaceutical composition for preventing and treating bacterial vaginosis. The pharmaceutical composition comprises the following traditional Chinese medicine materials in parts by mass: 25-35 parts of curcuma zedoary, 20-30 parts of fructus cnidii, 45-55 parts of radix sophorae flavescentis, 5-15 parts of alumen, 10-20 parts of fructus kochiae, 10-20 parts of rhizoma atractylodis, 90-110 parts of flos rosae rugosae, 10-14 parts of golden cypress, 8-10 parts of cortex dictamni, 4-6 parts of borneol, 8-12 parts of aloe vera gel, 1-3 parts of vitamin E, 0.1-0.2 part of hyaluronic acid, 0.2-0.4 part of polyhexamethylene biguanide hydrochloride, and 1-2 parts of lactic acid milk. The pharmaceutical composition provided by the invention has obvious inhibition effect on bacteria, also has obvious inhibition effect on candida albicans, but has no inhibition effect on lactobacillus. The pharmaceutical composition has obvious treatment effect on female bacterial vaginosis after clinical use, and has no stimulation on vagina.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, in particular to an external pharmaceutical composition for treating bacterial vaginosis. Background technique [0002] Bacterial vaginosis is one of the most common vaginal infectious diseases in women of childbearing age, causing not only vaginal inflammation, but also many other adverse outcomes, such as infertility and miscarriage, endometritis, disc inflammatory disease, etc. The incidence rate ranks first in vaginitis, and it is a disease that seriously threatens women's reproductive health. [0003] At present, the drugs commonly used to treat vaginosis include ciprofloxacin, ofloxacin, and cephalosporins, etc., which can be used to kill related pathogenic microorganisms, but at the same time destroy the beneficial flora in the vagina, resulting in various This kind of bacteria breeds rapidly, and various symptoms of vaginitis or vaginosis, abnormal leucorrhea and ...

AI Technical Summary

Problems solved by technology

[0003] At present, the drugs commonly used to treat vaginosis include ciprofloxacin, ofloxacin, and cephalosporins, etc., which can be used to kill related pathogenic microorganisms, but at the same time destroy the beneficial flora in the vagina, resulting in various This kind of bacteria breeds rapidly, and various symptoms of vaginitis or vaginosis appear, abnormal leucorrhea and odor, etc.

Other common medicines for external use include bacteria-cleaning lotions for fumigation and sitz baths or vaginal douching, vaginal itching lotions, etc. These medicines are inconvenient to use, poor in curative effect, or expensive, etc. limited clinical use

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