Synergistic fungicide
A technology of fungicides and additives, applied in the directions of fungicides, biocides, biocides, etc., can solve the problems of increased research and development costs, difficulty in the speed of pathogenic bacteria resistance, and difficulty in achieving obvious effects. The amount of use, the effect of good control effect
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[0018] The formulation of the synergistic fungicide is a dispersible oil suspension, and its preparation method is as follows: pyraclostrobin 0.01-30%, polyhexamethylene biguanide hydrochloride 0.01-0.5%, chlorogenic acid 0.01-15%, the total content of active ingredients is not more than 50%, dispersant 0.2-15%, wetting agent 0.2-10%, thickener 0.1-3%, antifreeze 0.1-5%, oily carrier to 100% . The specific production steps are: mixing the active ingredients and other additives, dispersing by high-speed shearing, and sanding in a sand mill to form a highly dispersed and stable suspension system in an oil-based medium to obtain the corresponding weight percentage Dispersible suspending agent.
[0019] The formulation of the synergistic fungicide is water-dispersible granule, and its preparation method is as follows: the formulation of the water-dispersible granule is composed of: pyraclostrobin 0.01-60%, polyhexamethylene 0.01-1.0% of biguanide hydrochloride, 0.01-30% of chlor...
Embodiment 1
[0031] Example 1 Determination of the combined effect of pyraclostrobin and polyhexamethylene biguanide hydrochloride on wheat rust.
[0032]
[0033] According to Sun Yunpei's method, the synergistic effect of drug mixture is evaluated according to the co-toxicity coefficient (CTC), that is, CTC≤80 is synergistic antagonism, 8050 / EC of test agent 50 ) × 100; Theoretical toxicity index TTI = the toxicity index of A agent × the percentage content of A agent in the mixture + the toxicity index of B agent × the percentage content of B agent in the mixture; co-toxicity coefficient (CTC) =[Actual Toxicity Index (ATI) of Mixture / Theoretical Toxicity Index (TTI) of Mixture]×100.
[0034] The joint action of pyraclostrobin and polyhexamethylene biguanide hydrochloride on wheat rust is determined, and the method refers to the method described in CN103975944 B.
[0035] Table 1 Laboratory toxicity test results of pyraclostrobin and polyhexamethylene biguanide hydrochloride against...
Embodiment 2
[0038] Example Indoor toxicity test of dipyraclostrobin and polyhexamethylene biguanide hydrochloride against Rhizoctonia solani.
[0039] The joint effect was evaluated by Wadley method
[0040]
[0041] Evaluation criteria: SR1.5, synergistic effect.
[0042] Table 2 Indoor toxicity test results of pyraclostrobin and polyhexamethylene biguanide hydrochloride against Rhizoctonia solani (inhibition of pathogenic fungus hyphae growth test-plate method, with reference to NY / T 1156.2-2006, after inoculation 3 day survey).
[0043]
[0044] The results of the data recorded in Table 2 show that the ratio of pyraclostrobin and polyhexamethylene biguanide hydrochloride in parts by mass of 60:1 has an antagonistic effect on the indoor antibacterial activity of Rhizoctonia solani, and the SR is less than 0.5.
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