2 results about "Phenanthrenes" patented technology

The application belongs to the technical field of pharmaceutical chemistry, and particularly relates to application of 1-pentyl-tetradecahydro-1H-cyclopenta[1,2-a]phenanthrene in treatment of acute myeloid leukemia. The application provides 1-pentyl-tetradecahydro-1H-cyclopenta[1,2-a]phenanthrene compounds with a novel skeleton. Experimental verification shows that the compounds have excellent inhibitory activity on AML cancer cells, and the mechanism is clear: the compounds can directly inhibit the activity of AML cancer cells, inhibit the proliferation of cancer cells by blocking the cell cycle process, and can specifically induce AML cancer cell apoptosis, thereby realizing the AML treatment effect. The application provides a new active compound candidate for the targeted treatment of acute myeloid leukemia, and lays an important foundation for the research and development of related drugs.

The present invention relates to the technical field of coal chemical product treatment, and specifically discloses a method for treating coking sulfur paste. The method for treating coking sulfur paste comprises the following steps: adding water to the pretreated coking sulfur paste to separate out water-soluble impurities; after centrifugation, separating out impurities such as coal powder according to density differences; performing microwave-assisted ethanol extraction to separate out benzenes and some polycyclic aromatic hydrocarbons; extracting with a second extractant, separating out phenanthrenes, and further preparing high-purity sulfur. At the same time, the present invention also treats the waste liquid generated in the above method with a composite microbial agent, effectively degrading safety monitoring indicators such as thiosulfates, thiocyanates, and polycyclic aromatic hydrocarbons (PAHs) in the waste liquid. The method for treating coking sulfur paste provided by the present invention has low energy consumption, low cost, no waste gas generation, and takes into account the effective treatment of waste liquid, having good economic and environmental benefits. The present invention can be applied to fields such as the treatment of coking sulfur paste, the preparation of sulfur, and the treatment of coking wastewater.