340 results about "Phosphine oxide" patented technology

The invention discloses a coating type high-molecular flame-retardant material. The composite material is prepared from the following components: organic silicon modified epoxy resin, a bio-based castor oil derivative, hydroxyapatite, carbon nanofibers, expanded graphite, ammonium polyphosphate, zinc borate, nano silicon dioxide, molybdenum oxide, microencapsulated red phosphorus, magnesium hydroxide, melamine cyanurate, aluminum diethylphosphinate, pentaerythritol, trihydroxymethyl phosphine oxide and a silane coupling agent. The coating is prepared from a titanate coupling agent, stearic acid, polyethylene glycol, 2, 6-butylated hydroxytoluene, triphenyl phosphite, 2, 4-dihydroxybenzophenone, sebacic diester, polytetrafluoroethylene micro powder, a modified polydimethylsiloxane flatting agent, organic montmorillonite, a polyether modified silicon defoaming agent and a solvent. The invention has the beneficial effects of high flame retardant efficiency, environmental friendliness, excellent comprehensive performance and excellent processability.

The invention discloses an aluminum substrate UV matt finish paint and a preparation process thereof, and relates to the technical field of paints.The aluminum substrate UV matt finish paint is prepared from, by mass, 10%-20% of modified polyurethane acrylate, 25%-32% of high-functionality aliphatic polyurethane acrylate, 18%-30% of special modified epoxy acrylate resin, 0.5%-2% of dispersing agent, 0.1%-0.5% of defoaming agent, 1%-3% of anti-settling powder and the balance water. The paint is prepared from the following components in percentage by weight: 10 to 15 percent of magnesium silicate mineral, 1 to 10 percent of matting powder, 0.2 to 1 percent of 1-hydroxycyclohexyl phenyl ketone, 0.5 to 3 percent of trimethylbenzoyl-diphenyl phosphine oxide, 1 to 3 percent of acrylate flatting agent, 0.2 to 1.2 percent of polyurea modified polyurethane rheological agent and 5 to 15 percent of trimethylolpropane triacrylate. According to the UV matte finishing paint disclosed by the invention, through compounding of ternary resin and enhancement of nano silicon dioxide, a rigid and tough cross-linked network is constructed, a paint film is free of cracks when being bent at 180 degrees, the adhesive force reaches grade 0, and a coating is resistant to acid and alkali etching liquid and free of corrosion by cooperating with a silane coupling agent and a light stabilization system, and the color difference is delta Elt after the UV matte finishing paint is subjected to high temperature of 260 DEG C; and 1.5, the anti-yellowing performance is excellent.

A photoinitiator including 2 to 6 monoacyl phosphine oxide moieties characterized in that the monoacyl phosphine oxide moieties are linked to each other via their acyl group and that at least 2 monoacyl phosphine oxide moieties have a chemical structure differing in the phosphine oxide part.

The invention provides a method for preparing high-purity hafnium tetrachloride by wet extraction and separation, which comprises the following steps: stirring and leaching hafnium alloy waste serving as a raw material by using HNO3 and HF mixed acid, then adding thioacetamide, adjusting the pH value to 4-5, stirring and filtering; compounding tributyl phosphate, trioctylphosphine oxide and sulfonated kerosene to obtain a composite extracting agent, and stirring and mixing to form a homogeneous organic phase; in a hydrochloric acid medium, controlling the volume ratio of an organic phase to a water phase to be (2.5-3.5): 1, carrying out three-stage counter-current extraction, and standing for phase splitting; the extracted organic phase passes through an adsorption column filled with iminodiacetic acid modified silica gel; and carrying out reverse extraction by using a hydrochloric acid solution, and then carrying out reduced pressure evaporation concentration, cooling crystallization and dehydration to obtain hafnium tetrachloride. According to the method, the zirconium and hafnium separation efficiency in the hafnium tetrachloride preparation process is improved, and the problem that the content of zirconium and hafnium impurities in the product is too high is solved.

The invention discloses a preparation method of silicone rubber and the silicone rubber, and belongs to the field of silicone rubber. The preparation method comprises the following steps: dispersing fumed silica in an acid solution to obtain a fumed silica solution, dispersing chitosan in a dilute acid solution to obtain a chitosan solution, mixing the fumed silica solution and the chitosan solution, stirring, centrifuging, washing and drying to obtain a coated product; mixing the coated product, magnesium hydroxide, raw rubber, a cross-linking agent, a vulcanizing agent and a catalyst, heating and kneading, and vacuumizing to obtain initial silicone rubber; the preparation method comprises the following steps: dissolving 1-hydroxycyclohexyl phenyl ketone into an organic solvent to obtain a solution A, mixing acrylic acid, phenyl bis (2, 4, 6-trimethylbenzoyl) phosphine oxide and titanium dioxide to obtain a solution B, soaking initial silicone rubber into the solution A, taking out, airing, soaking into the solution B, and carrying out ultraviolet curing, cleaning and airing to obtain the silicone rubber. The heat-conducting property, the mechanical property and the wet friction property of the silicone rubber are greatly improved.

An acyl phosphine oxide initiator wherein the acyl group is selected from the group consisting of a benzoyl group substituted by an urea group or an oxalylamide group; a 2,6-dimethyl benzoyl group substituted in position 3 by an urea group or an oxalylamide group; a 2,6-dimethoxy benzoyl group substituted in position 3 by an urea group or an oxalylamide group; a 2,4,6-trimethyl benzoyl group substituted in position 3 by an urea group or an oxalylamide group; and a 2,4,6-trimethoxybenzoyl group substituted in position 3 by an urea group or an oxalylamide group.

The invention belongs to the technical field of UV visbreaking polymers, and particularly relates to a UV visbreaking film and a preparation method thereof. Wherein the UV viscosity-reducing film sequentially comprises a base film (1), a first viscosity-reducing adhesive layer (5), a second viscosity-reducing adhesive layer (4) and a release film (3) from bottom to top, the first viscosity-reducing adhesive layer (5) and the second viscosity-reducing adhesive layer (4) both comprise a photoinitiator, the photoinitiator in the first viscosity-reducing adhesive layer (5) is 1-hydroxy-cyclohexyl phenyl ketone, and the content of the photoinitiator in the formula of the adhesive layer is 0.1%-10% by mass; a photoinitiator in the second viscosity-reducing adhesive layer (4) is bis (2, 4, 6-trimethylbenzoyl) phenyl phosphine oxide, and the content of the photoinitiator in the adhesive layer formula is 0.1-10% by mass; in the preparation method, ultraviolet irradiation precuring is carried out, so that the UV viscosity-reducing film has light selectivity and high cohesion strength, and the residual adhesive is remarkably reduced.

The invention discloses a hyperbranched flame retardant as well as a preparation method and application thereof. The flame retardant is prepared by the following steps: dehydrating and pre-polymerizing a boron-containing component (such as tetrahydroxy diborane) and dihydric alcohol (such as 1, 3-propylene glycol), and condensing with trihydroxymethyl phosphine oxide. 4 parts of the flame retardant is added into epoxy resin, phosphorus-containing free radicals can be released in a gas phase for quenching and smoke suppression, a compact boron-containing expanded carbon layer is formed in a condensed phase, and synergistic flame retardance is achieved. The hyperbranched structure can be embedded into an epoxy network, synchronous reinforcement and toughening are achieved, the impact strength is improved by 123.5%, and the tensile strength is improved by 47.7%. The flame retardant has efficient flame retardance (the limit oxygen index is 33.9%, UL-94V-0 level), high transparency and excellent mechanical properties, and is suitable for epoxy resin composite materials in the fields of electronic packaging, aerospace and the like.

The application discloses a kind of rapamycin 40-position hydroxyl alkyl synthesis method, belong to the technical field of drug synthesis.The method is: in inert gas atmosphere, rapamycin is sequentially added into microwave reaction tube, molecular sieve and additive, additive is triphenyl phosphine oxide, tri (4-fluorophenyl) phosphine oxide, tri (4-methoxyphenyl) phosphine oxide, tricyclohexyl phosphine oxide, triphenyl phosphine sulfide, triphenyl phosphine selenide or hexamethylphosphorus triamide;Subsequently, alkylating agent, base and organic solvent are added, sealed, reacted in microwave reaction instrument, cooled, filtered, washed, dried, filtered, purified, to obtain the alkylated product of rapamycin 40-position hydroxyl group.The method compared with the existing rapamycin 40-position hydroxyl group alkyl modification method, simple operation, low cost, short reaction time, less impurities, easy separation, higher yield, up to 79.1%, suitable for industrial production, can provide new ideas for synthesis and development of rapamycin derivatives such as everolimus.

The present invention relates to the technical field of polymer materials, and discloses a halogen-free flame-retardant and temperature-resistant epoxy resin and a preparation method thereof. The epoxy resin is prepared from epoxy resin, nitrogen-phosphorus-silicon tetrafunctional epoxy resin, curing agent and diluent through blending and curing. The nitrogen-phosphorus-silicon tetrafunctional epoxy resin is obtained by using 4-maleimidobenzoic acid, 1,3-bis(3-aminopropyl)tetramethyldisiloxane, bis(4-methoxyphenyl)phosphine oxide and epichlorohydrin as raw materials through condensation, addition and substitution reactions. The nitrogen-phosphorus-silicon has a synergistic flame-retardant effect and plays a good role in heat insulation, mass isolation and oxygen isolation. The tetrafunctional epoxy resin molecule contains more epoxy groups, can react with the curing agent to form more cross-linking points, improve the cross-linking density, and can more effectively disperse and resist stress. The epoxy resin prepared by the present invention has excellent flame-retardant effect, is halogen-free and environmentally friendly, and has good temperature resistance and mechanical properties at the same time.

A UV curable inkjet ink including a free radical polymerizable compound and an acyl phosphine oxide initiator wherein the acyl phosphine oxide initiator includes an acyl group selected from the group consisting of a benzoyl group substituted by an urea group or an oxalylamide group; a 2,6-dimethyl benzoyl group substituted in position 3 by an urea group or an oxalylamide group; a 2,6-dimethoxy benzoyl group substituted in position 3 by an urea group or an oxalylamide group; a 2,4,6-trimethyl benzoyl group substituted in position 3 by an urea group or an oxalylamide group; and a 2,4,6-trimethoxybenzoyl group substituted in position 3 by an urea group or an oxalylamide group wherein the urea group and the oxalylamide group include a tertiary amine group positioning a phosphorus atom of the acylphosphine oxide initiator in a 1 to Z position, where position 1 is defined as that of the phosphorus atom and position Z is defined as the nitrogen atom of the tertiary amine group with Z representing an integer of at least 11; and that the acyl phosphine oxide initiator contains no more than two photoinitiating moieties having a phosphine oxide group.

The invention belongs to the technical field of UV ink formula design and digital printing application, and particularly relates to scratch-resistant UV ink, a preparation method thereof and application of the scratch-resistant UV ink to digital printing. The scratch-resistant UV ink comprises the following raw materials in parts by weight: 15-25 parts of epoxy acrylate; 10 to 20 parts of polyurethane acrylate; 15 to 25 parts of a bifunctional monomer; 5-10 parts of a monomer with three functional groups and more than three functional groups; 3 to 5 parts of an alpha-hydroxy ketone photoinitiator; 2 to 4 parts of an acyl phosphorus oxide photoinitiator; 2 to 5 parts of organically modified nano silicon dioxide; 0.1 part to 0.5 part of a flatting agent; 0.5 to 1.5 parts of a dispersing agent; 10 to 15 parts of pigment; the bifunctional monomer is tripropylene glycol diacrylate; the monomer with three functional groups and more than three functional groups is trimethylolpropane triacrylate. The ink has pencil hardness greater than or equal to 3H and excellent flexibility, the adhesive force on substrates such as PC, PET, metal and the like reaches 0 level, the printing process is simplified, and the ink is suitable for digital printing in various scenes.

The invention discloses a lithium dihydrogen phosphate preparation method, which comprises: S1, mixing a refined lithium sulfate solution with an extraction agent solution, and carrying out standing layering to obtain an upper layer solution; s2, mixing the upper-layer solution with a detergent, washing, and separating to obtain a washing solution; s3, mixing the washing liquid with a phosphoric acid solution, and standing for layering to obtain a lower-layer solution; s4, mixing the lower-layer solution with a component regulator; and carrying out solid-liquid separation. An extracting agent in the extracting agent solution comprises at least one of benzoyl trifluoroacetone, trialkyl phosphine oxide and sulfonated calixarene. The specific extraction agent efficiently selects lithium ions to separate impurities, lithium dihydrogen phosphate is obtained through direct reverse extraction after washing, lithium dihydrogen phosphate does not need to be converted into other lithium products to prepare lithium dihydrogen phosphate, and the process production period is shortened. In addition, lithium dihydrogen phosphate is prepared through washing and reverse extraction after impurities are efficiently selected and separated through an extraction agent; the purity is high; the battery grade lithium dihydrogen phosphate can be obtained.

The invention discloses a preparation method of 3, 6-dichloropyridazine, and belongs to the technical field of chemistry. According to the method, 3, 6-dihydroxypyridazine is used as a raw material, an organic solvent and triphenylphosphine oxide are combined to form a dichlorotriphenylphosphine intermediate state which is used as a chlorinating agent, dihydroxyl is substituted to generate 3, 6-dichloropyridazine, triphenylphosphine oxide and solid light are used as raw materials, heating reaction is performed to prepare 3, 6-dichloropyridazine, meanwhile, a one-pot method can be adopted in the two-step reaction, and operation is easy and convenient. The novel preparation method for synthesizing 3, 6-dichloropyridazine provided by the invention has the advantages of low raw material cost, high yield, high gas phase purity and no pollution, is suitable for industrial production, can meet industrial requirements, provides a new idea for later preparation of 3, 6-dichloropyridazine, has the remarkable advantages of high gas phase purity and high yield, and is suitable for industrial production. Wide application prospects are realized.

The invention discloses a synthesis method of a novel benzosuberone compound, and belongs to the field of organic synthesis. The preparation method comprises the following steps: uniformly stirring methyltriphenylphosphonium bromide in a solvent at room temperature, dropwise adding an n-hexane solution of n-butyllithium in an ice-water bath, stirring a reaction system at room temperature for 30-40 minutes after dropwise adding is completed, then adding an initial raw material phenanthrenequinone 1 in the ice-water bath, transferring the reaction system to 40 DEG C for reaction, and after the reaction is monitored to be complete by a TLC (Thin Layer Chromatography) dot plate, filtering, washing and drying to obtain the phenanthrenequinone 1. And pouring the reaction liquid into a silica gel chromatographic column, and simply filtering by using dichloromethane as an eluent to remove salt and phosphine oxide. And performing rotary evaporation to remove the organic solvent to obtain a crude product, and separating and purifying to obtain a target product 2. The method is short in reaction time and low in reaction cost, provides a practical method for obtaining the seven-membered rigid ring skeleton, and has potential value for synthesis of natural products and bioactive molecules.

The invention discloses a functional polyester yarn and a preparation method thereof. The functional polyester yarn is formed by blending functional synthetic fibers and bamboo fibers according to the mass ratio of (3-5): 0.5. The functional synthetic fiber is prepared from the following raw materials: polyester chips, a functional copolymer, a compatilizer, an antioxidant, a lubricant, 1, 4-diamino-2, 3-dicyanoanthraquinone and (3, 6-diamino-9-acridinyl) boric acid. The functional copolymer comprises structural units introduced by the following monomers: diphenyl (4-vinyl phenyl) phosphine oxide, 4-methyl-5-vinyl thiazole, 1-allyl-3-methyl imidazole chloride, 3-(1, 1-difluoro-2-propylene-1-yl)-2 (1H)-quinoxalinone, and 1, 3-bis (oxiranyl methyl)-5-(2-allyl)-1, 3, 5-triazine-2, 4, 6 (1H, 3H, 5H)-triketone. The yarn is good in anti-ultraviolet performance, flame retardant performance and antibacterial performance.

The invention provides a method for recovering rhodium in organic residual liquid containing triphenylphosphine / phosphine oxide, and relates to the technical field of precious metal recovery, and the method comprises the following steps: S1, carrying out reduced pressure rectification on the organic residual liquid containing triphenylphosphine / phosphine oxide to remove volatile components until the indexes of the residual liquid meet the feeding requirements of a subsequent process, and collecting light components for independent storage; s2, adding an acidic medium into the organic phase after light component removal, stirring and heating, introducing an oxidizing agent to carry out oxidation-complexation reaction, maintaining reaction conditions until the reaction is complete, standing for phase splitting, and collecting a water phase containing rhodium complex ions; according to the method, a core process combining oxidation-chlorination transfer and anion exchange adsorption is adopted, and key parameters of each process are accurately controlled, so that the rhodium recovery rate is stabilized at 95% or above, the rhodium content in the residual liquid can be reduced to 5 ppm or below, the industrial emission standard is completely met, and compared with the prior art, the resource recovery efficiency is greatly improved, and the cost is reduced. And waste of precious metal resources is effectively reduced.

The invention discloses an anti-aging cable for photovoltaic power generation and a preparation method thereof, and relates to the technical field of cables. The anti-aging cable for photovoltaic power generation prepared by the invention comprises a conductor and a protective layer, the protective layer comprises modified polyethylene, modified silicon dioxide and phenylamino-terminated silicone oil, and the modified polyethylene is obtained by grafting polyethylene with N, N-dimethyl-3-buteneamine and then reacting with 3-(tert-butyl)-5-(chloromethyl)-2-hydroxybenzaldehyde; the modified silicon dioxide is obtained by grafting pretreated silicon dioxide with stilbene phosphine oxide and then carrying out formylation; and finally, uniformly mixing and extruding the modified polyethylene, the modified silicon dioxide and the phenylamino-terminated silicon oil to obtain the protective layer. The anti-aging cable for photovoltaic power generation prepared by the invention has good flame retardance, mechanical property and anti-aging property.

The invention discloses a recyclable water-based metal cutting fluid and a preparation method thereof. The cutting fluid comprises the following raw materials in parts by weight: 32-36 parts of base oil, 8-12 parts of amines, 9-12 parts of a surfactant, 0-8 parts of an extreme pressure agent, 6-9 parts of a lubricant, 4-6 parts of an antirust agent, 0-2 parts of a bactericide, 2-4 parts of a coupling agent, 0.1-1 part of a defoaming agent and the balance of deionized water. The preparation method comprises the following steps: dissolving the amine in water in advance, adding the anti-rust raw material into the amine solution, fully stirring until the anti-rust raw material is completely dissolved, finally adding the base oil, the surfactant and other additives, and continuously stirring until the anti-rust raw material is completely clarified and transparent. The preferable antirust agent is tris (2-carboxyethyl) phosphine oxide, the excellent extreme pressure effect and bactericidal performance are achieved through carboxyethyl and phosphine oxide structures contained in the tris (2-carboxyethyl) phosphine oxide, and the finished product has good long-term stability, high oil film lubricity and excellent antirust and anti-corrosion performance.

Provided is a carbon dioxide absorbent that has excellent carbon dioxide absorption performance. The present invention provides a compound for a carbon dioxide absorbent, said compound being characterized by being a phosphine oxide compound represented by general formula (1) (where, a, b, and c each represent an integer of 1-10, R1, R2, and R3 each independently represent an amino group or a hydroxy group, and at least one of R1, R2, and R3 represents an amino group).

The invention provides a method for constructing an aryl C-P bond through a reaction of an Ar-F compound of a nickel catalysis electron donating group, which comprises the following steps: in the presence of a nickel catalyst, an additive and alkali, carrying out a coupling reaction on a substituted aryl compound in a formula B and a compound in a formula C diphenylphosphine oxide in an organic solvent to generate an aryl phosphine oxide compound in a formula A, the reaction formula is shown in the specification, Ar is or, and R is an electron-donating group. The method disclosed by the invention has the effects that the substrate has universality, the operation is simple, the condition is mild, a noble metal catalyst and a phosphine ligand are not needed, the cost is low, and the yield is high.

The invention discloses a trifluoromethyl-containing polysubstituted phosphorus-doped six-membered ring phosphine oxide compound as well as a preparation method and application of the trifluoromethyl-containing polysubstituted phosphorus-doped six-membered ring phosphine oxide compound. A diene-containing three-stage phosphine oxide compound is used as a raw material, a trifluoromethyl reagent and a nucleophilic reagent are used, in the presence of a transition metal copper catalyst and a pyridine-oxazoline ligand, a free radical domino cyclization reaction is initiated to obtain the compound, C-O, C-N and C-C coupling is realized, and the variety of the nucleophilic reagent can be changed, so that the structure of the product is diversified. The diastereoisomers can be separated, the yield of a single diastereomer can reach 85%, and the diastereoisomers have excellent diastereoselectivity. The invention provides a novel reaction mode of constructing a polysubstituted phosphorus-doped six-membered ring by mediation of free radicals, the reaction condition is mild, the operation is simple, the substrate universality is good, a novel skeleton structure of an organic phosphine reagent is provided, and the variety diversity of the organic phosphine reagent is expanded. The synthesized compound can be used as a catalyst to be applied to Appel reaction, and has a good application prospect.

The invention provides a preparation method of photocatalytic hydrogel, belongs to the technical field of photocatalysis, and aims at solving the problems that traditional hydrogen production is high in energy consumption and pollution, and existing photocatalytic hydrogel is low in purity and unstable in performance. The method comprises the following steps: firstly, preparing seven precursors of CPDT-1, CPDT-2Br-SO3Na, PCT-SO3Na, Flu-2Br-SO3Na, PFT-SO3Na, PCBT-SO3Na and PFBT-SO3Na step by step, and carrying out nitrogen purging to prevent oxidation, acetone precipitation, recrystallization and Soxhlet extraction and purification in the process; the four active precursors are mixed with acrylic acid, pentaerythritol triallyl ether and (2, 4, 6-trimethylbenzoyl) diphenyl phosphine oxide respectively, the mixture is subjected to 365nm ultraviolet irradiation polymerization, and four photocatalytic hydrogels are prepared. The method has the advantages of mild conditions, controllable operation, high product purity and stable photocatalytic performance, and is suitable for hydrogen energy preparation and water pollution treatment.

The application provides a kind of eutectic solvent and its preparation method and application, the eutectic solvent includes hydrogen bond donor compound and hydrogen bond acceptor compound, the structural formula of hydrogen bond donor compound is wherein, R1 and R2 independently selected from n-octyl or iso-octyl, the hydrogen bond acceptor compound includes tri-n-octyl phosphine oxide.The eutectic solvent can be efficiently extracted from the permanent magnet rare earth waste hydrochloric acid solution of transition metal, can reduce the use of a large amount of organic solvent in the traditional extraction process.

This invention provides a novel phosphine oxide compound that inhibits SHP2, a composition thereof, a method for preparing the compound, and a method for treating SHP2-related diseases (such as cancer).

A process for the preparation of a compound of the sterically hindered alkoxyamine class is described, the process comprises the step of alkylating a sterically hindered hydroxylamine compound to a corresponding sterically hindered alkoxyamine by reacting said sterically hindered nitroxyl compound with a compound capable of producing a carbon-central alkyl radical, typically a territorial or secondary alkyl radical, the compounds capable of generating carbon-center alkyl radicals are selected from thermal radical initiators that form radical species in the temperature range of 40 DEG C to 200 DEG C, and from photoinitiators that undergo light excitation when irradiated with UV light or visible light in the range of 180 to 700 nm, in particular UV light in the range of 180 to 380 nm, the compounds capable of generating carbon center alkyl radicals are typically selected from the class of organic peroxides, azo compounds, benzoyl derivatives, benzophenone derivatives, thioxanthone derivatives, benzoin derivatives, benzoyl phosphine oxide derivatives, and the like. The invention relates to a peroxide, for example, selected from the group consisting of diacyl peroxides of formula (A), peracid esters of this formula (A), and oxalic acid peracid esters of formula (D) R-CO-O-O-Z-R (A), r-Z ''-X-CO-CO-O-O-Z''-R (D) wherein each R independently represents a primary or secondary alkyl or cycloalkyl group, preferably comprising from 1 to 15 carbon atoms, and X is oxygen-O-or peroxy-O-O-, Z represents CO or an alkylene group bonded to a quaternary carbon atom, the quaternary carbon atom being an alkylene group of formula (C) R '-C-R' (C), wherein each R'is selected from alkyl groups having 1 to 15 carbon atoms, and Z "represents the alkylene group bonded to a quaternary carbon atom having the formula (C). The described process produces the corresponding O-alkylated derivatives of the sterically hindered hydroxylamines, typically compounds of the class referred to as N-O-alkyl HALS, with very high selectivity and conversion and without the need for the use of catalysts, in particular metal catalysts.

The invention relates to the field of organic synthesis, in particular to a synthesis method of gamma-aminophosphine oxide compounds and derivatives thereof. According to the synthesis method disclosed by the invention, alpha, beta-unsaturated amide, diaryl phosphine oxide or phosphite ester is taken as raw materials, and under the action of acid, the gamma-aminophosphine oxide compound can be rapidly and efficiently synthesized by a one-pot method. The preparation method comprises the following steps of: generating conjugated nitrile positive ions or imine salt intermediates with strong electrophilicity from alpha, beta-unsaturated amide under the activation of acid, converting diaryl phosphine oxide or phosphite ester into strong nucleophilic three-coordination phosphorus species under the action of alkali, and further performing phosphorus-doped Michael addition reaction on the conjugated intermediates to finally generate the gamma-aminophosphine oxide compounds. According to the method disclosed by the invention, diaryl phosphine oxide or phosphite which is cheap, easy to obtain and stable in structural property is used as a phosphorus source, the substrate applicability is wide, and the economic cost is relatively low; in addition, the method realizes synthesis of a target product without participation of a metal catalyst, and is rapid and efficient.

The invention provides a lithium coordination extraction micro-cluster as well as a preparation method and application thereof. The lithium coordination extraction micro-cluster is obtained by assembling beta-diketone containing a benzene ring, alkyl phosphine oxide containing the benzene ring and a hydrocarbon compound containing the benzene ring through hydrogen-bond interaction. The lithium coordination extraction micro-cluster obtained by assembling the three substances through hydrogen-bond interaction not only can generate coordination with Li < + >, but also can generate repulsion on ions such as Na < + >, K < + > and B2O4 < 2->, is completely insoluble in water and has extremely high hydrophobicity, so that lithium can be effectively and selectively extracted from a lithium-containing solution, residues are not generated in a water phase, and the lithium-containing solution can be recycled. Therefore, the method is especially suitable for extracting lithium from alkaline salt lake brine in the Tibet autonomous region.

The invention discloses a synthesis method of a polysubstituted internal alkenyl phosphine oxide derivative. Internal alkenyl sulfonium salt which is simple, easy to prepare and high in reaction activity is used as a raw material, diaryl phosphine oxide is used as a coupling reagent, and the Z / E isomer of the polysubstituted internal alkenyl phosphine oxide derivative is simply and efficiently synthesized through a displacement substitution reaction. Compared with the reported alkenyl phosphine oxide synthesis method, the method has the characteristics of stable raw material structure, low price, easiness in obtaining, very mild reaction conditions, simplicity in experimental operation, high reaction efficiency and good functional group compatibility, and two isomer products Z / E can be obtained through one-step separation and purification.

The invention provides a method for preparing a chiral helicene compound through cyclization reaction of an iridium-catalyzed 3-aryl indazole biaryl compound and disubstituted alkyne. The method comprises the following steps: under the action of an iridium catalyst, a chiral cyano phosphorus-oxygen ligand and an additive, carrying out an intermolecular asymmetric carbon-hydrogen bond activation reaction on a 3-aryl indazole biaryl compound and disubstituted alkyne, and after the reaction is finished, separating to obtain the chiral diazaspirene-containing compound, according to the invention, synthesis of the chiral helicene compound is realized through a transition metal catalysis asymmetric carbon-hydrogen bond activation method, the research technology of Cp metal catalysis asymmetric carbon-hydrogen bond activation is further developed, and the synthesis strategy of the chiral helicene compound is expanded at the same time; reaction substrates are wide in universality, and chiral control in the reaction process is realized through the chiral cyano phosphine oxide, so that the product has very high enantioselectivity; various chiral helicene compounds are synthesized, the synthesis method is simple and convenient, and the atom economy is high.