10 results about "M-aminoacetophenone" patented technology

The invention relates to the technical field of naphthalimide preparation, in particular to a synthetic method of naphthalimide derivatives. Comprising the following steps: dissolving a mixture of 1, 8-naphthalic anhydride and 4-aminoacetophenone in acetic acid containing sodium acetate, carrying out a reflux reaction, after the reaction is completed, cooling the mixture to room temperature, filtering to obtain a crude product, and washing to obtain a pure compound 1; the method comprises the following steps: dissolving a mixture of a compound 1, a hydrazine derivative and an acid catalyst in an organic solvent, carrying out a reflux reaction, after the reaction is completed, cooling the mixture to room temperature, filtering to obtain a crude product, and washing to obtain the naphthalimide compound. The synthesis reaction is safe and reliable, the process is simple and easy to control, and the reaction yield is high; the combination of the synthesized drug and DNA has spontaneity, and the drug has good anti-proliferative activity.

An electrophotographic photoreceptor includes: a conductive base, a photosensitive layer provided on the conductive base, and a protective layer provided on the photosensitive layer. The protective layer is a cured body of a photocurable composition that includes a photocurable compound and a photopolymerization initiator. The photopolymerization initiator includes a first compound having an acylphosphine oxide structure and a second compound having an α-aminoacetophenone structure and an absorption coefficient at a wavelength 365 nm smaller than that of the first compound. A total content of the first compound and the second compound with respect to 100 parts by mass of the photocurable compound is 5 parts by mass or more and 20 parts by mass or less.

The present invention provides a curable composition which is (1) capable of enhancing curability, (2) capable of lowering a curing shrinkage rate, (3) capable of enhancing hardness of a cured product obtained therefrom, and (4) capable of enhancing thermal cycle characteristics of a cured product obtained therefrom.　A curable composition according to the present invention contains a photocurable compound and a photopolymerization initiator, wherein: the photocurable compound contains a first (meth)acrylate compound which has two or more (meth)acryloyl groups and an alicyclic skeleton; the curable composition optionally contains a thermosetting component in an amount of less than 10 wt%; and (1) the photopolymerization initiator contains a photopolymerization initiator that has an α-aminoalkylphenone skeleton and a molecular weight of 800 or more, or (2) the photopolymerization initiator contains a photopolymerization initiator that has an α-aminoacetophenone skeleton, and the content of the photopolymerization initiator that has an α-aminoacetophenone skeleton is 0.5 wt% to 3 wt% inclusive in 100 wt% of the curable composition.

The invention relates to the technical field of organic synthesis, in particular to o-aminoacetophenone and a preparation method thereof.The preparation method comprises the steps that S1, under the protective atmosphere, o-nitroethylbenzene, tetrahydrofuran and ethyl alcohol are mixed and subjected to an illumination reaction for 10-15 min, and an intermediate product is obtained; s2, the intermediate product is subjected to a secondary reaction, and o-aminoacetophenone is obtained. According to the preparation method provided by the invention, the use of a strong oxidant (such as potassium permanganate) and a noble metal catalyst is avoided, the reaction system is green and environment-friendly, the product purity is high, the post-treatment is simple and convenient, and the whole process has remarkable economical efficiency and sustainability.

The invention relates to a sulfonamide compound containing thiazole heterocycle as well as a preparation method and application of the sulfonamide compound, and belongs to the technical field of agricultural chemicals and bactericides. According to the invention, substituted sulfonyl chloride and unsubstituted or substituted aminoacetophenone are used as main raw materials, the thiazole heterocyclic ring and a sulfonamide group are effectively combined through different reactions to prepare the novel sulfonamide compound containing the thiazole heterocyclic ring, and the structural general formula is shown as a formula I or a formula II. The compound provided by the invention has bacteriostatic activity on multiple plant pathogenic fungi such as sclerotinia sclerotiorum, rhizoctonia solani, botrytis cinerea, curvularia maydis, fusarium oxysporum, pyricularia grisea and the like, and an innovative solution is provided for agricultural sustainable disease prevention and control.

The present invention discloses a heteroaromatic hyperbranched conjugated polymer, its preparation method and application. The structural unit of the polymer is shown as follows. It is synthesized by A3-coupling reaction. The solvents and catalysts used are environmentally friendly, the reaction conditions are mild, and the reaction steps and post-treatment are simple. Hg<supgt;2+< / supgt; ions and 2'-aminoacetophenone have obvious quenching effects on the fluorescence of the polymer solution, and 17β-estradiol has obvious enhancement effects on the fluorescence of the polymer solution. It can be used for the detection of Hg<supgt;2+< / supgt> ions, 17β-estradiol and 2'-aminoacetophenone. It not only has simple operation and short response time, but also has high selectivity and low detection limit for Hg<supgt;2+< / supgt> ions, 17β-estradiol and 2'-aminoacetophenone, and is expected to be used as a chemical detector.

The invention relates to the field of effective and economical conversion of nitro or nitroso compounds in to corresponding amines. More it discloses a reduction processes of nitro or nitroso compounds to corresponding amino compounds, which exhibit differential solubility, exemplified & not restricted to the processes discussed for m-aminoacetophenone, the intermediate of Phenylephrine, ethyl3- [[4-(methylamino)-3-aminobenzoyl](pyridin2yl)amino]propanoate the intermediate of Dabigatran, and 2,4-Difluoroaniline the intermediate of Pantoprazole. Even more particularly, the invention relates to a process involving use of minimal quantity of water or quantity of water required only as the source of hydrogen for generation of sufficient reduction potential to perform the chemical reaction. The process offers a. safer, cost competitive and greener alternative to the conventional process of reduction. A key benefit of the invention is that it avoids side product / s & / or impurity / s resulting from usage of large quantity of water especially when other sensitive / reactive groups are present in the molecule.

The invention belongs to the technical field of medicine and chemical industry, and discloses an imidazoline spiroquinazolinone compound and a preparation method and application thereof.The compound is novel in structure, has an imidazoline and quinazolinone double-ring structure, has multiple active sites and large modifiable space, shows good biological activity application potential, and can be used for preparing a novel compound. The compound has the activity of selectively inhibiting phosphodiesterase 7 (PDE7). Meanwhile, 2-aminoacetophenone, isocyanate and amidine which are low in price and easy to obtain serve as starting raw materials of the compound, a spiro-bicyclic system is directly constructed through one-pot series cyclization, and the preparation method has the advantages that the raw materials are easy to obtain, steps are simple, atom economy is high, the reaction system is green and simple, aftertreatment is simple and convenient, amplification is easy and the like.

The invention relates to the technical field of organic chemical synthesis, in particular to a 2-sulfonyl aminopyrrole derivative and a preparation method thereof, and the preparation method comprises the following steps: in the presence of a copper compound, performing one-pot reaction on an alpha-amino acetophenone compound as shown in a formula (II), a terminal acetylenic ketone compound as shown in a formula (III) and a sulfonyl azide compound as shown in a formula (IV) to obtain the 2-sulfonyl aminopyrrole derivative. The 2-sulfonyl aminopyrrole derivative as shown in the formula (I) is obtained. A copper compound is used as a catalyst, no oxidizing agent or reducing agent needs to be added, under the promotion of alkali, an alpha-amino acetophenone compound, terminal alkyne ketone and a sulfonyl azide compound are subjected to a one-pot reaction in an organic solvent, and the 2-sulfonyl aminopyrrole derivative which is a diastereoisomer is obtained in one step. The preparation method has the advantages of one-pot reaction, simple and efficient reaction, diversified three-dimensional structure of the product, high yield, wide substrate application range, easiness in separation and purification of the product, good purity and wide industrial application prospect.

A curable resin composition which has high light sensitivity and good touch dryness and can obtain good flexibility, welding heat resistance and cross-sectional shapes, a dry film, a cured product and an electronic component. The curable resin composition comprises: (A) a carboxyl-containing resin having a bisphenol F backbone, (B) a photopolymerization initiator, (C) a photosensitive monomer, (D) an epoxy resin, and (E) an inorganic filler, wherein the photopolymerization initiator (B) comprises: (B1) an aminoacetophenone-based photopolymerization initiator, and (B2) a benzophenone-based photopolymerization initiator; and the photosensitive monomer (C) comprises: (C1) a di(meth)acrylate having a polypropylene glycol backbone.