646 results about "O-hydroxyacetophenone" patented technology

An ink set for inkjet recording is provided that includes at least a colored liquid composition comprising at least a radically polymerizable compound, a photopolymerization initiator, and a colorant, and an undercoat liquid composition comprising at least a radically polymerizable compound and a photopolymerization initiator, the colored liquid composition comprising as the photopolymerization initiator at least one type of α-aminoacetophenone compound, and the undercoat liquid composition comprising as the photopolymerization initiator at least one type of compound selected from the group consisting of an acylphosphine oxide compound, an α-hydroxyacetophenone compound, and an oxime ester compound. There is also provided an inkjet recording method employing the ink set for inkjet recording, the method including a step of applying the undercoat liquid composition on top of a recording medium, a step of semi-curing the undercoat liquid composition, and a step of carrying out image formation by discharging the colored liquid composition on top of the semi-cured undercoat liquid composition.

The invention relates to a preservative containing capryloyl hydroximic acid and p-hydroxy phenyl ethyl ketone and a preparation method and application of the preservative and a cosmetic containing the preservative, and belongs to the field of preservatives. The preservative containing the capryloyl hydroximic acid and the p-hydroxy phenyl ethyl ketone is prepared by stirring the raw materials in percentage by weight: 5-30% of capryloyl hydroximic acid, 10-40% of p-hydroxy phenyl ethyl ketone, 30-60% of C3-C8 dihydric alcohol at 45-75 DEG C and adding 3-10% of a solubilizer for stirring at 45-75 DEG C. The preservative can be added to the cosmetic for application, and the adding amount is 0.5-5.0wt%. The preservative containing the capryloyl hydroximic acid and the p-hydroxy phenyl ethyl ketone has efficient broad-spectrum sterilization capability, does not release harmful substances of formaldehyde and the like, has good bactericidal and bacteriostatic preservative effects when applied to the cosmetic, and also has the effects of being mild and free of thrill to skin.

The invention relates to a mixture of compounds having the sensory properties of winter-green, to fragrance and flavoring compositions containing said mixture and to flavored and perfumed products containing said mixture, to a method of adding a wintergreen flavor, odor or note to (non-wintergreen) flavored or perfumed products. Further the present invention relates to the use of said mixture as an enhancement, or as complete or partial replacement for methyl salicylate, in particular in chewing gum, foods, dentrifices, mouthwashes and other orally consumable products. The mixture comprises or consists of dihydroanethole, o-anisaldehyde, 1,3-dimethoxybenzene, 2′-hydroxyacetophenone, and optionally 2-methoxyacetophenone.

The invention belongs to the technical field of cosmetics, and particularly discloses double-layer essence with repair and anti-aging functions. The double-layer essence comprises, by weight, 1.0%-2.0% of PEG-40 (polyethylene glycol-40) hydrogenated castor oil, 5%-19% of methyl trimethicone, 4%-6% of dicaprylyl carbonate, 0.5%-1.5% of cetyl dimethicone, 0.5%-1.5% of helianthus annuus seed oil, 3%-9% of glycerin, 0.1%-0.15% of sodium hyaluronate, 0.5%-1.5% of myrothamnus flabellifolia leaf/stem extract, 1%-3% of polypeptides with palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, 0.5%-1.5% of lactobacillus ferment lysate, 1%-3% of glycosphingolipid, 0.8%-1% of mixtures of glycerol caprylate, p-hydroxy phenyl ethyl ketone and glyceryl laurate and the balance water. The double-layer essence has the advantages that the double-layer essence which is a novel ultralow-viscosity double-layer system is unique in structure and convenient to use; formulas and structures of the double-layer essence are optimized, and accordingly the double-layer essence is free of potential irritation and allergy sources such as perfume and preservatives, is in mild and non-irritant formulas and has the excellent repair and anti-aging functions.

Disclosed is a Sofalcone preparation method which mainly comprises, (1) subjecting p-hydroxybenzaldehyde and 2,4-ihydroxyacetophenone to condensation reaction under alkaline condition, obtaining 2,4,4-Trihydro-xychalcone, (2) subjecting 2,4,4-trihydro-xychalcone and 1-bromo-3-methyl-2-butene to condensation reaction, obtaining 2-hydroxyl-4,4-bis (3-methyl-2-butenyloxy) chalcone, (3) subjecting the 2-hydroxyl-4,4-bis (3-methyl-2-butenyloxy) chalcone and ethyl bromoacetate to condensation under the action of potasium carbonate, thus obtaining sofalcone. The mol ratio of p-hydroxybenzaldehyde, 2.4-dihydroxyacetophenone, 1-bromo-3-methyl-2-butene, and ethyl bromoacetate can be 1 : (0.90-1.50) : (1.60-2.55) : (0.60-1.25).

The invention discloses a chiral tridentate PNN ligand and application of the same in asymmetric hydrogenation and similar reactions. The tridentate nitrogen phosphine ligand disclosed in the invention has been the first reported nitrogen phosphine ligand containing chiral oxazoline so far and has been successfully applied to high-efficiency and high-selectivity hydrogenation and similar reactions of ketone and imine salts. Compared with other ligand, the ligand provided by the invention is simpler in synthetic route, higher in yield and environment-friendlier; moreover, the metal complex of the ligand shows better selectivity and a higher turn-over number in asymmetric hydrogenation. An iridium complex of the chiral tridentate PNN ligand has successfully realized asymmetric reduction of beta-ketone ester into beta-alcohol ester (which is a raw material for synthesis of molecular drugs duloxetine and atomoxetine), asymmetric hydrogenation of alpha-hydroxyacetophenone into alpha-hydroxyphenylethyl alcohol and asymmetric hydrogenation of acetophenone into phenylethyl alcohol, which is of important significance to production of the medical industry.

The invention relates to the technical field of cosmetics, and particularly relates to a deep water replenishing and moisture preserving cream and a preparation method. The deep water replenishing andmoisture preserving cream solves the problems of poor moisture preserving effect, certain irritation and poor water replenishing effect in the prior art. The deep water replenishing and moisture preserving cream is prepared by mixing the following raw materials in parts by weight: a moisture preserving agent, a skin moisturizing agent, an emulsifying agent, a skin conditioning agent, a thickeningagent which comprises 0.03-0.1% of carbomer, a neutralizing agent which comprises 0.03-0.08% of triethanolamine, a preservative which comprises 0.3-0.8% of 1,2-hexanediol, 0.2-0.5% of p-hydroxyacetophenone, and 0.01-0.1% of essence, and the balance of deionized water. The deep water replenishing and moisture preserving cream is free from alcohol, hormone and pigment and is capable of effectivelypreventing skin moisture from loss and enables moist and full skin in all times; in addition, the cream has the characteristics of being easily absorbed by skin, soft and smooth, relieving dry skin, and being smooth but not greasy; the prevention capacity of the skin can be improved; the outside irritation can be resisted.

A kind of polyimide material will produce pyridine diphenol and its ramification by condensation reaction between hydroxyl hypnone and substituted benzaldehyde. The etherification reaction will occur to the products and 3-nitryl-near chlorine benzotrifluoride and will derive binitro compound. The binitro compound will be deoxidized into diamine monomer of aromatic trifluoromethyl by the ethanol solution of iron dust/HCl. This monomer will derive polyamic acid solution by adding molecular weight regulator, assistant adhesive and aromatic tetracid dual-anhydride. The polyamic acid solution will become into aromatic polyimide after being processed by chemical imine or heat imine.

The invention relates to synthesis of a triamine containing a symmetrical triaryl pyridine structure and hyperbranched polyimide thereof. The triamine monomer is BB'2-type aromatic triamine, namely 2,4,6-tris[4-(4-aminophenoxy)-phenyl] pyridine the structure of which is shown in the specification. The triamine is prepared by the following three steps: firstly reacting p-hydroxybenzaldehyde with p-hydroxyacetophenone in acetic acid to obtain 2,4,6-tris(4-hydroxyphenyl) pyridine, then reacting 2,4,6-tris(4-hydroxyphenyl) pyridine with p-chloronitrobenzene to obtain 2,4,6-tris[4-(4-nitrophenoxy)-phenyl] pyridine, and finally reducing the trinitro compound by use of hydrazine hydrate in the presence of a carbon-supported palladium catalyst to synthesize 2,4,6-tris[4-(4-aminophenoxy)-phenyl] pyridine. The hyperbranched polyimide of the triamine is an amino-terminated or anhydride-terminated hyperbranched polyimide polymer obtained by polymerization of the triamine monomer and a commercial dianhydride monomer. The prepared hyperbranched polyimide has excellent high-temperature resistance, solubility and optical properties; and the hyperbranched polyimide polymer material has great application value and prospects in the fields of photosensitive, optical waveguide and gas permeation separation membranes and other materials.

The invention relates to a method of using recombinant strain to asymmetrically transform and manufacture (R)-phenyl glycol, which belongs to the field of biological catalytic asymmetric transforming technique. The invention inserts the (R)-specific alcohol dehydrogenase gene rcr into the vector pET21c to construct a recombinant plasmid pET-RCR which is transformed to the E.coli to construct the recombinant plasmid E.coli BL21/pET-RCR. The recombinant strain has the capability of asymmetrically catalyzing the 2-hydroxy phenyl ethyl ketone into (R)-phenyl ethylene glycol. Under optimized reaction condition, the 2.5-10 percent isopropanol is added to pH 8.0 Tris-HCL buffer as an auxiliary substrate, the 0.1-0.4g/ml recombinant cell solution is used for transforming the 0.5-5g/L 2-hydroxy phenyl ethyl ketone substrate for 48h, the product (R)-phenyl ethylene glycol with optical purity of 80-100 percent e.e. and productive rate of 70 to 100 percent is finally gained. The invention not only provides an effective way to manufacture (R)-phenyl ethylene glycol, but also makes sense for developing the biological catalyst for the chiral transformation.

The invention belongs to the fields of organic synthesis and pharmaceutical chemistry, and relates to a total synthesis preparation method and an application of natural product flavonoid compounds. The method comprises the following steps: respectively carrying out a 4-step reaction and a 8-step reaction on 2,4,6-trihydroxyacetophenone used as a raw material to complete total synthesis of a natural product Morin (1); and respectively carrying out a 7-step reaction and a 9-step reaction on the Morin (1) used as a raw material to complete total synthesis of a natural product Sanggenol F (2). The method has the advantages of easily available raw materials, stable intermediate, mild conditions, easily controlled reaction, and important reference and utility values in massive production of the Morin and the Sanggenol F. The prepared Morin (1) can be used to prepare anti-oxidation drugs, anti-diabetes drugs, immunoloregulation drugs or antitumor drugs; and the prepared Sanggenol F can be used to prepare metabolic disease resisting drugs, and the metabolic disease resisting drugs are insulin sensitizers, blood sugar lowering drugs or blood fat lowering drugs.

The invention discloses an essence liquid containing tuber melanosporum extract and a preparation method thereof. The essence liquid comprises a component A, a component B and water. The component A comprises butanediol, diglycerin, sodium polyacrylate, xanthan gum, modified potato starch, betaine and disodium ethylenediaminetetraacetate. The component B comprises mulberry leaf extract, tuber melanosporum extract, a lactobacillus/soybean milk fermentation product filtrate, purslane extract, bifida ferment lysate filtrate, grapefruit seed extract, bifida ferment lysate, Aloe vera leaf polysaccharide, beta-glucan, 1, 2-pentanediol, 1, 2-hexanediol, p-hydroxyacetophenone, cladosiphon novae-caledoniae extract, hydrolyzed rice bran extract, a rice fermentation product filtrate, soluble proteoglycan, aloe extract, licorice root extract, radix angelicae sinensis, salvia miltiorrhiza flower/leaf/root extract, cornus officinalis fruit extract, wolfberry root extract, tremella polysaccharide, hyaluronic acid, and the balance of deionized water.

The invention relates to preparation processes of bambuterol hydrochloride and an intermediate thereof. The bambuterol hydrochloride is synthesized by taking 3,5-dihydroxyacetophenone as a starting raw material and undergoing esterifying, brominating, reducing, condensing and salting reactions. Compared with other processes, the process has the advantages that: the technical problems of industrial production are solved, each step of reaction is simple, and conditions are mild; and the process is a preparation process with the lowest cost at present, and is successfully applied to industrial production.

The invention discloses an anti-aging composition with various hyaluronates, which comprises, by weight, 1-10% of butylene glycol, 1-5% of hydrolyzed hyaluronic acid, 1-5% of sodium acetylated hyaluronate, 0.1-5% of sodium hyaluronate, 0.1-5% of a sodium hyaluronate crosslinked polymer, 0.1-5% of hydroxypropyl trimethyl ammonium chloride hyaluronic acid, 0.1-1% of oligopeptide-1, 0.01-1% of blackend swallowwort root extract, 0.1-0.5% of PEG-60 hydrogenated castor oil, 0.1-0.5% of p-hydroxyacetophenone, 0.1-1% of octanohydroxamic acid, and the balance of deionized water, adding up to 100%. Theanti-aging composition has extended functions, provides both moisturizing and skin repairing and soothing; since the anti-aging composition is water soluble, the anti-aging composition is not limitedto product forms and is addable to liquids, milks, creams, essences and the like.

The invention belongs to the technical field of cosmetics, and particularly relates to whitening cream and a preparation method thereof. The whitening cream comprises the following preparation raw materials of nicotinamide, resveratrol, 3-o-ethyl ascorbic acid, a peony extract, diglucosyl gallic acid, a caviar extract, phosphatidylcholine, ceramide 3, p-hydroxyacetophenone, tocopheryl acetate, sodium hyaluronate, 7-10% of a humectant, an emollient, an emulsifying agent, a thickening agent, a neutralizer, essence and water. The whitening cream disclosed by the invention can take effect in multiple ways of melanin generation inducement, melanin generation process, melanin transfer, melanin digestion and discharge process and the like, and the purpose of quickly whitening skin and dispellingfreckles can be achieved.

The invention discloses a nursing agent for skin moisturizing and repairing. The nursing agent for skin moisturizing and repairing comprises the following components by mass percentage: 0.05 0.15% ofdisodium EDTA, 0.5-3.0% of nicotinamide, 2.0-5.5% of glycerin, 2.5-5.5% of propylene glycol, 0.05-0.35% of xanthan gum, 0.05-0.5% of sodium hyaluronate, 0.15-0.5% of p-hydroxyl acetophenone, 1.0-5.0%of caprylic/capric triglyceride, 1.0-3.0% of polydimethylsiloxane, 1.0-5.0% of isononyl isononanoate, 0.5-5.0% of jojoba seed oil, 0.5-2.5% of avocado tree fruit oil, 1.75-10.5% of repair essential oil, 0.05-0.5% of fullerenes, 0.35-2% of repairing essence, 0.2-3.5% of cetostearyl alcohol, 1.0-2.5% of cetearyl olivate, 1.0-2.5% of sorbitan olivate, 0.1-1.0% of lecithin, 0.5-5.0% of oligopeptide-1, 0.1-0.5% of D-panthenol, 0.5-2.5% of a Centella asiatica extract, 0.5-2.5% of 1,2-hexanediol, and the balance of deionized water. The product of the invention can quickly improve the moisture retention of the skin, obviously improves the dryness of the skin, increases the moisture content in the skin, and makes the skin appear young. .

The invention mainly discloses a synthetic method of p-hydroxyacetophenone. According to the synthetic method, phenol and acetic anhydride are taken as raw materials so prepare phenylacetate; under catalytic action of aluminium trichloride, o-dichlorobenzene is added for reaction, steam distillation is carried out, active carbon filtration is carried out, and crystallization is carried out so as to obtain p-hydroxyacetophenone; and then p-hydroxyacetophenone is also prepared via two times of circular reaction of o-dichlorobenzene layer and phenylacetate, wherein the o-dichlorobenzene layer contains o-hydroxyacetophenone and is obtained via layering of a product of the former reaction. Compared with the prior art, the synthetic method possesses following advantages: side product suppression assistant circulating method (three times of continuous operation, and two times of circulation) is adopted, o-dichlorobenzene containing o-hydroxyacetophenone is used in circulation process, generation of o-hydroxyacetophenone in subsequent process is reduced effectively, p-hydroxyacetophenone yield is increased by 10% at least, and HPLC detection purity is 99.7% or higher. The synthetic method is capable of increasing p-hydroxyacetophenone yield, realizing reasonable cyclic utilization of side product, and reducing production cost, and is suitable for industrialized production.

The invention relates to acne cream capable of effectively removing acnes and lightening acne marks. The acne cream comprises water, glycerinum, butanediol, a hamamelis virginiana extract, an aloe vera extract, neopentyl glycol diheptanoate, octanoic acid/capric acid triglyceride, meadowfoam seed oil, squalane, macadimia nut oil, butyrospermum parkii kotschy grease, nicotinamide polydimethylsiloxane, cetostearyl alcohol, cetearyl glucoside, sorbitan olivate, cetearyl olivate, sodium hyaluronate, dipotassium glycyrrhizinate, oligopeptides-1, arbutin, L-ascorbyl dipalmitate, a calendula extract,a lavender extract, an acroloyl-dimethyl taurine amino/VP copolymer, a sodium acrylate/acroloyl-dimethyl taurine sodium copolymer, isohexadecane, polysorbate-80, fullerene, an angelica sinensis extract, p-hydroxyacetophenone, 1,2-hexanediol, sweet orange flower oil and EDTA (Ethylene Diamine Tetraacetic Acid). The acne cream is prepared through a series of procedures and has the characteristics of good acne treatment effect, no acne mark, no side effect, and the like.

The invention discloses diaper rash cream and a preparation method thereof. The diaper rash cream is prepared from the main components of petrolatum, caprylic/capric triglyceride, avocado tree fruit fat, polyglyceryl-4 isostearate, meadowfoam seed oil, gallnut extract, microcrystalline wax, polydimethylsiloxane, Sorbitan olivate, Quaternium-18 Hectorite, propylene glycol, Chrysanthellum indicum extract, sodium dehydroacetate, butanediol, hydrolyzed rice protein, Anthemis nobilis flower extract, radix sophorae extract, fructus cnidii extract, Bisabolol, Ginger Root Extract, Hexyldecanol, Brassinosteroids, N-palmitoyl hydroxyproline cetyl ester, stearic acid, menthol, tocopheryl acetate, perfume, p-hydroxyacetophenone, caprylyl glycol, 1,2-hexanediol, chlorhexidine diacetate, disodium EDTA and water through synergistic interaction in an appropriate ratio by the scientific preparation method, and the produced diaper rash cream has good skin care and skin-firming effect and good affinity,can relieve skin pain, and has good stability.

The invention discloses a substituted arone derivate, an aryloxy-phenoxy, and a carboxylic acids compound formed by the derivates of the aryloxy-phenoxy. The compound shows a good effect in pharmacological research, can reduce cholesterol, low-density lipoprotein and triglyceride in the blood at the same time, and has obvious advantages on efficacy. The conventional p-hydroxyacetophenone or aryloxy-phenoxy compound has no capacity of reducing the three components at the same time and nearly plays no effect to the p-hydroxyacetophenone and triglyceride; and the aryloxy-phenoxy compound does not work well with respect to the cholesterol and the low-density lipoprotein. The compound with a dosage of 80mg/kg has the capacity of reducing the cholesterol and the low-density lipoprotein similar to the capacity of the p-hydroxyacetophenone with the dosage of 150mg/kg.