14 results about "Phenyl acetate" patented technology

A process for producing 4-hydroxyacetophenone (4-HAP) comprises the steps of providing phenyl acetate and methanesulfonic acid (MSA) source; feeding the phenyl acetate and the MSA source into a reactor; and allowing the phenyl acetate and the MSA to react under conditions suitable for forming 4-HAP by Fries rearrangement to yield a 4-HAP containing phase.

The invention discloses a method for preparing phenyl acetate with high selectivity. A phosphoric acid solution is added into a magnesium chloride solution, stirring and heating are performed to obtain a suspension, the suspension is dried to constant weight to obtain a white solid, the white solid is ground to obtain powder, and the powder is calcined to obtain the catalyst. Then mixing phenol and a catalyst, placing the mixture in an oil bath for reflux reaction, dropwise adding acetic anhydride, distilling after the reaction is finished, and collecting a fraction at 190-195 DEG C, namely phenyl acetate. According to the magnesium chloride loaded phosphoric acid type catalyst (MgCl2-H3PO4) prepared by the method disclosed by the invention, phenol and acetic anhydride react without a solvent, MgCl2-H3PO4 is a solid catalyst, can be recycled only by filtering and can be repeatedly used after being washed, and MgCl2-H3PO4 also improves the selectivity of phenyl acetate and reduces the production cost.

Described in this application are host cells comprising heterologous polynucleotides encoding a 4-hydroxybenzoate decarboxylase (4-HB DC) and / or an acetyl transferase, as well as methods of culturing the host cells. Also described are methods of producing a product of interest, such as phenyl acetate or phenol, using the host cells described herein.

The invention discloses a foam liquid crystal elastomer for enhancing energy absorption by utilizing microsphere-induced shear deformation as well as a preparation method and application thereof, and relates to the technical field of liquid crystal elastomers. The preparation method of the foam liquid crystal elastomer comprises the following steps: mixing 2-methyl-1, 4-phenylene bis (4-(3-(acryloyloxy) propoxy) benzoate with methylbenzene, heating until the mixture is completely dissolved, adding 2, 2 '-(1, 2-ethanedioxy) diethyl mercaptan and tetrakis (3-mercaptopropionic acid) pentaerythritol ester, and uniformly stirring to obtain a liquid crystal elastomer solution; heating and expanding the microspheres, adding a liquid crystal elastomer solution in a heat preservation state, and uniformly stirring, or directly adding the microspheres into the liquid crystal elastomer solution at 85 DEG C, heating, and uniformly stirring; adding a catalyst or a photoinitiator, and uniformly stirring to obtain a foam liquid crystal elastomer solution; and pouring the foam liquid crystal elastomer solution into a mold, curing, and demolding to obtain the foam liquid crystal elastomer with high-strength energy absorption capacity.

The invention discloses a synthesis method of p-hydroxyacetophenone. The method comprises the following steps: by taking nitrobenzene as a solvent, adding phenyl acetate into the solvent, then adding silicon dioxide loaded aluminum chloride as a catalyst, heating in an oil bath for reaction, filtering reaction liquid to separate out the catalyst, adding distilled water into residual reaction liquid, taking a lower oil phase, carrying out reduced pressure distillation to recover nitrobenzene, adding a saturated sodium bicarbonate solution into residual raffinate, and oscillating; and separating a water phase and an organic phase, taking the water phase, adjusting the pH value to 2-3, collecting the separated solid, and washing to obtain the p-hydroxyacetophenone. The catalyst can reduce the reaction activation energy, so that the reaction rate and the conversion rate are improved; the catalyst and the solvent can be recycled, so that the treatment cost of three wastes is reduced, and the requirements of atom economy and sustainable development in modern green chemistry are better met.

This invention provides a method for synthesizing p-hydroxyacetophenone, comprising the following steps: simultaneously introducing phenyl acetate and a solution containing anhydrous hydrogen fluoride into a microchannel reactor to carry out a rearrangement reaction, wherein the rearrangement reaction is carried out at a temperature of 40-140°C and a pressure of 1-2 MPa, to obtain crude p-hydroxyacetophenone. This invention helps to improve the conversion rate of phenyl acetate and the selectivity of p-hydroxyacetophenone.

A process for producing 4-hydroxyacetophenone (4-HAP) comprises the steps of providing phenyl acetate and methanesulfonic acid (MSA) source; feeding the phenyl acetate and the MSA source into a reactor; and allowing the phenyl acetate and the MSA to react under conditions suitable for forming 4-HAP by Fries rearrangement to yield a 4-HAP containing phase.

This invention provides a method for synthesizing p-hydroxyacetophenone, comprising the following steps: introducing a solution containing anhydrous hydrogen fluoride into a reaction vessel containing phenyl acetate to carry out a rearrangement reaction, wherein the rearrangement reaction is carried out at a temperature of 80-140°C and a pressure of 1-2 MPa, to obtain crude p-hydroxyacetophenone. This invention helps to improve the conversion rate of phenyl acetate and the purity of p-hydroxyacetophenone.

The invention discloses a novel inhibitor for apatite in calcium (magnesium) collophanite and application of the novel inhibitor, and belongs to the technical field of phosphorite beneficiation. According to the method, sodium ethylenediamine di-o-phenyl acetate is used as an inhibitor for separating and recycling apatite from calcium (magnesium) collophanite through reverse flotation, a high separation effect is achieved on the basis of low cost, environment friendliness and low reagent dosage, and reverse flotation can be conducted on complex low-grade phosphorite; and the contradictory relation between the high-grade phosphorite reserves and the consumption is effectively relieved.

A process for producing 4-hydroxyacetophenone (4-HAP) comprises the steps of providing phenyl acetate; charging the phenyl acetate and anhydrous hydrogen fluoride (HF) in a reactor; and allowing the mixture of the phenyl acetate and the HF to react under conditions suitable for forming 4-HAP by Fries rearrangement. Process for recovery of 4-HAP, comprising:providing a 4-HAP containing phase;extracting the 4-HAP from the 4-HAP containing phase into a first organic solvent, preferably ethyl acetate, phase;evaporating the first organic solvent, preferably ethyl acetate, from the 4-HAP containing first organic solvent, preferably ethyl acetate, phase; subsequently, recrystallizing the 4-HAP from water; and optionally, recrystallizing the 4-HAP from a heptane phase before the recrystallization from water.

The invention provides a method for synthesizing p-hydroxyacetophenone. The method comprises the following steps: producing phenyl acetate by using isopropyl acetate and phenol as raw materials; phenyl acetate is dissolved by using a mixed solvent, and a composite catalyst is adopted for catalysis, so that generation of by-products is reduced; gradient hydrolysis and purification are adopted, the yield and purity of the p-hydroxyacetophenone are effectively improved, and the p-hydroxyacetophenone prepared through the synthesis method has the advantages of being high in purity and yield; and the preparation method is simple and easy to control, simple in post-treatment process and suitable for industrial large-scale production.

The invention relates to the technical field of medicine synthesis, and particularly discloses a synthesis method of besudil mesylate. The besudil mesylate is prepared by taking 3-(4-chloroquinazoline-2-yl) phenyl acetate and 5-amino-1H-indazole-1-tert-butyl formate as initial raw materials through four-step reaction, compared with the traditional process, the reaction route is obviously simplified, the yield loss caused by accumulation of multi-step reaction can be effectively reduced, and the yield of besudil mesylate is increased. And the complexity and the operation difficulty of the synthesis process are reduced. Meanwhile, the intermediate compounds B, C and D all have Boc protecting groups, so that the reaction in each step has higher selectivity, and the purity of the target product is favorably improved. In addition, the synthetic route provided by the invention is mild in reaction condition, the safety of the process can be effectively improved, the reaction energy consumption is reduced, the adopted reagent is relatively environment-friendly, the treatment is relatively easy after the reaction is finished, serious pollution to the environment is avoided, and the industrial prospect is high.

This invention provides a method for producing irregularly shaped microparticles using a simple method. [Solution] A method for producing irregularly shaped fine particles having an uneven surface or a non-spherical shape. Hydrogen-bonding raw material monomers, an organic solvent, and a polymerization initiator are charged together into a reaction vessel, and precipitation polymerization is carried out. The hydrogen-bonding monomers are one or more acrylate-based or methyl (meth)acrylate-based compounds having an aromatic structure. Ester-based solvents are preferred as the solvent. In particular, it is preferable to select and use at least one from the group consisting of phenyl acetate, ethyl acetate, butyl acetate, 2-ethoxyethyl acetate, and methyl benzoate.

Described herein are processes for the preparation of 2-(pyridin-2-yloxymethyl)-phenyl acetic acid esters that are useful as intermediates for agricultural products. These methods comprise reacting a substituted pyridine with a phenylacetic acid alcohol dianion derived from 3-isochromanone. The intermediate may be further reacted to form an agricultural product such as a fungicide.