962results about How to "Atom utilization is high" patented technology

The invention provides a preparation method for (I) 2- amido -2-[2-(4- alkyl phenyl)ethyl]-1ú¼3- propanediol, which comprises: using alkyl benzene (II) as initial material, with Lewis acid existing, to take Friedel-Crafts acylating reaction with 3- halogenated propionyl chloride and generate beta- halogenated alkylpropiophenone (IV); reducing IV by hydride to obtain 3- nitro -1-(4- alkyl phenyl) propanol (V); preparing 2- nitro -2- methylol -4-(4- alkyl phenyl)-1ú¼4butanediol (VI) by hydroxymethylation; reducing nitro and removing benzalcoholhydroxy to VI and obtaining the objective product.

The invention provides a synthesis method of a palladium nano sheet, and relates to a palladium nano material. The method comprises the following steps: adding a palladium precursor, a surface protectant, and halogen ion-containing organic salt or halogen ion-containing inorganic salt to a solvent to obtain mixed liquor; placing the mixed liquor under a carbon monoxide atmosphere, and heating to 10-200 DEG C; and then cooling to room temperature, adding acetone, carrying out centrifugal purification, and cleaning to obtain the palladium nano sheet. The synthesized palladium nano sheet has the advantages of high yield greater than 80%, uniform particle diameter with the deviation smaller than 10%, ultrathin structure with the thickness about 1.8nm, larger specific area, high atom utilization ratio and favorable electro-catalytic activity. The size of the obtained palladium nano sheet can be well adjusted. The palladium nano sheet has good near-infrared spectrum absorption feature, has prodigious potential application in the biological thermal therapy, such as the application in the near-infrared thermal therapy for tumors; and the palladium nano sheet has favorable electro-catalytic performance.

The invention discloses an aluminum oxide loaded PtCu monatomic alloy catalyst and a preparation method and application thereof. The catalyst takes Al2O3 as a carrier, takes Cu as an auxiliary, and loads a small amount of active components Pt; the mass percent of Pt is 0.025%-0.15%, and the mass percent of Cu is 5%-20%; and during preparation, a co-impregnation method is used, the Al2O3 carrier isimpregnated in an aqueous solution of chloroplatinic acid and copper nitrate, the PtCu / Al2O3 catalyst is obtained after drying and roasting and high-temperature reduction, and the catalyst has high activity and high stability, and is low in price and low in toxicity. The catalyst is suitable for reaction for producing olefin by dehydrogenation through low alkane, and is particularly suitable forreaction for producing propylene by dehydrogenation through propane in a hydrogenation atmosphere, the dehydrogenation activity is quite high under the condition of high temperature, the selectivity of the propylene can reach 90% or above, the stability is good, the use amount of Pt is small, the utilization rate is high, and compared with an industrial Pt series catalyst, the aluminum oxide loaded PtCu monatomic alloy catalyst is cheaper.

The invention provides a preparation method of Roxadustat intermediate 4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylate (IV), comprising the step of subjecting 2-(1-(3-phenoxyphenyl)ethylimide)dimalonate (III) as a starting material to condensation and cyclization. The preparation method of the Roxadustat intermediate IV has the advantages that material is easy to obtain, operating steps are few, the process is simple, the reaction yield is high, atom utilization rate is high, and the method is easy for industrial production. The reaction general formula is shown in the specification.

The present invention relates to a graphene material inlaid with single metal atoms, the preparation method thereof and its application of being used as the catalyst for the electroreduction of carbon dioxide. The graphene material inlaid with single metal atoms comprises single metal atoms and graphene; the single metal atoms are dispersed in the framework of the graphene; and the graphene is at least one selected from N doped graphene and N and S co-doped graphene. The material is used for the electrochemical reduction reaction of carbon dioxide, which significantly improves the utilization efficiency of the metal atoms and enhances the catalytic activity for the electroreduction of carbon dioxide, improves the catalytic stability, inhibits effectively the hydrogen evolution reaction, improves the selectivity for CO product, and broadens the electric potential window of reducing carbon dioxide to generate CO.

The invention discloses a novel preparation method of netaglinide oxazolone shown in the formula (IV), which comprises the following steps: under the action of a catalyst A, enabling 3-fluorine-4-morpholine phenyl isocyanate shown in the formula (I) to react with (R)-epoxy chloropropane to obtain a compound (II), wherein the catalyst A is magnesium diiodide, magnesium dibromide, magnesium dichloride, magnesium perchlorate or magnesium trifluoromethanesulfonic acid; enabling the compound (II) to react with sodium azide to obtain a compound (III); reducing the compound (III) by hydrogenation, and then, acetylating the reduced compound (III) to obtain the compound (IV). In the invention, the low-cost and environment-friendly catalyst (Lewis acid magnesium) is used for catalyzing the cycloaddition reaction of the (R)-epoxy compound and the isocyanate to establish a mother nucleus structure of the netaglinide oxazolone by one step, thus the prepared netaglinide oxazolone has high stereoselectivity, does not need rigorous operation conditions, such as low temperature, no water, no oxygen and the like, has the advantages of moderate reaction conditions, simple and convenient operation, high utilization ratio of atoms, environment protection, low production cost and the like, and is suitable for industrialized production.

The invention provides an electrolyte for a lithium secondary battery, the electrolyte includes a material which can be reacted with a corrosion matter on the surface of a negative electrode of the lithium secondary battery to form a silicon-containing protection layer, and the lithium secondary battery includes a lithium-oxygen secondary battery or a lithium-sulfur battery. According to the characteristic that corrosion matter lithium hydroxide is formed inevitably on the lithium surface of the lithium secondary battery of the opening system, a silicate material and / or silane material are / is added in the electrolyte, and the silicate material and / or the silane material are / is easy to react with the lithium hydroxide to form a silicon-containing protection film, further erosion of the lithium negative electrode can be effectively prevented, and with the charge and discharge, silicate / silane in the electrolyte can dynamically repair of the protective film, namely, growth of the protection film is continued on the corroded lithium surface, in the circulating charge and discharge process, the lithium negative electrode can be dynamically protected in real time in situ, the effect is better, the protective layer is more compact, metal lithium corrosion can be effectively reduced, and the metal lithium reversibility can be significantly improved.

The invention provides a preparing method of a carbon-loaded monoatomic metal nitrogen-containing compound oxygen reduction catalyst. The method comprises the steps of pre-oxidizing nitrogen-containing biomass at a first high temperature, after a pre-oxidized product is uniformly mixed with a transition metal source and a pore-forming agent, conducting first calcination at a second high temperature in an inert gas atmosphere, after a calcined product is subjected to acid pickling, washing and drying, conducting second calcination again at the second high temperature, and finally, obtaining thecarbon-loaded monoatomic metal nitrogen-containing compound oxygen reduction catalyst. The preparing method has the advantages of being low in raw material cost, simple in preparing technology and the like; the prepared catalyst has the advantages of being high in pH universality, atom utilization rate, catalytic performance and stability, excellent in methyl alcohol resistance and the like, is expected to replace expensive carbon-loaded platinum catalysts, and is about to have a wide application prospect in efficient and cheap large-scale commercialized fuel cells.

The invention provides a method for preparing baricitinib. The method comprises the following steps: by taking 4-pyrazol boric acid pinacol ester (10) as an initial raw material, performing Michael addition reaction on the initial raw material and 3-(icyanomethylene) azacyclo-cyclobutane-1-tert-butyl formate (11) so as to prepare an intermediate 12, and performing catalytic coupling reaction on 12 and 13, thereby preparing an intermediate 14; removing two-molecule tert-butyl formate of the intermediate 14, thereby preparing an intermediate 15; performing sulfamide reaction on the intermediate 15 and ethanesulfonyl chloride in an organic solvent, thereby obtaining a final product baricitinib (1). The method for preparing baricitinib has the advantages that the raw materials are easy to obtain, the process is simple, the operation is convenient, the reaction yield is high when being compared with that of document records, the atom utilization rate is high, industrial production can be easily achieved, and the like. The reaction general formula is as shown in the specification.

The invention discloses a preparation method of a monoatomic catalyst for indoor air purification. The preparation method comprises the following steps of (a) performing preparation to obtain a yellow solid powder CeO2 carrier; (b) dissolving RuCl3.3H2O into deionized water to obtain dipping liquid, wherein the mass concentration of ruthenium in the dipping liquid is 5 to 50 mg / mL; and (c) preparing the monoatomic catalyst: adding the CeO2 carrier obtained by the step (a) into the dipping liquid obtained by the step (b) by a dipping method, adding an iodoform solution dissolved into glycol, mixing uniformly, dipping, drying the dipped solution on a rotary evaporator and calcining to finally obtain the monoatomic catalyst Ru / CeO2. By the method, the general catalytic reaction dosage (the load capacity is very low) is extremely small, and the atom utilization rate is extremely high.

The invention relates to a preparation method of hydroxylamine salt, which adopts a hydroxylamine synthesis assembly process. The preparation method comprises the following steps: (1) preparation of cyclohexanone-oxime: carrying out one-step synthesis on ammonia water, oxydol and cyclohexanone by using a titanium silicon molecular sieve as a catalyst and water as a reaction medium to obtain the cyclohexanone-oxime; and (2) synthesis of hydroxylamine: carrying out acidic hydrolysis on the cyclohexanone-oxime to generate he hydroxylamine salt and byproduct cyclohexanone, wherein the generated cyclohexanone can be used as a raw material to reenter the green assembly process and participate in the reaction (1). The invention has the advantages of high atom utilization ratio and high yield of the hydroxylamine salt product, the raw material cyclohexanone (oxime) can be recycled, and the titanium silicon molecular sieve catalyst is reusable, thereby saving the production cost.

The invention provides a method for coproducing cyclohexanol and alkanol. The method comprises the following steps: preparing benzene and / or cyclohexane into cyclohexene, carrying out addition-esterification on the cyclohexene in a catalytic distillation tower, obtaining carboxylic acid / cyclohexyl carboxylate material flow at the bottom of the tower, hydrogenating the material flow to obtain the cyclohexanol and the alkanol. The esterification and hydrogenation reactions in the method have high conversion rate and selectivity, and high atom economy; the process is environment-friendly; the alkanol is coproduced when the cyclohexanol is produced, in particular, when acetic acid is used, the cheap acetic acid is converted into ethanol with high cost and large market capacity in an indirect manner, so as to increase the economical efficiency of the process.

The invention is concerned with immobilization ion liquid activators, production for the dihydroxylation of olefin and the method producing rare H2O2 solution into vicinal diol by those activators and under the acidity condition with organic solution or without organic solution. The said activator is based with immobilization ion liquid and loaded transition metal active center. The activator can be reused and the loaded transition metal tungsten is innocuous and cheap. Compare with traditional method, it takes rare H2O2 solution as oxidant with high utilization ratio and cleaning to avoid pollute for too much of organic acid. The transform ration is 98 percent of H2O2 during the process without organic solution and superfluous olefin and the separate ration of 1,2-cyclohexanediol is 92 percent. The activator can be reused for eight times and still has good active nature and the process is easy and applied for industry exploitation.

The invention belongs to the technical field of preparation of selenium-containing polymers, and discloses a method for preparing polyselenourea / polyselenoamide through multi-component polymerizationof elemental selenium, isonitrile / alkyne and amine. The method comprises: carrying out a reaction on elemental selenium, a binary triple bond compound and a diamine in an organic solvent under an inert atmosphere, and subsequently treating to obtain a selenium-containing polymer, wherein the binary triple bond compound is binary isonitrile or binary alkyne, and the selenium-containing polymer is polyselenourea or polyselenoamide. According to the present invention, the method has characteristics of mild reaction conditions, high efficiency, energy saving, no catalyst, no by-product generation,atomic economy, green chemistry, low monomer toxicity, high atom utilization rate and high yield (more than or equal to 90%); the group has strong tolerance, and a variety of functional groups can beintroduced into the monomer; and the polyselenourea / polyselenoamide is stable, and can be degraded under specific conditions.

The invention provides a preparation method and applications for a metal monoatomic material. The method selects a metallic compound containing a metal-nonmetal coordination structure; destruction toa catalytically active structure can be effectively prevented through a processing mode of performing pyrolysis after the metallic compound, a protective agent and any carbon substrates are simply mixed; and therefore, the metal monoatomic material can be efficiently prepared and shows good performance. The technical route of the method is simple and effective and has universality and good application prospects.

The invention provides a method for co-producing cyclohexanol and ethanol, which is characterized in that benzene is taken as an initial raw material, selective hydrogenation through benzene, addition esterification of cyclohexene, and hydrogenation of acetate and cyclohexyl acetate are carried out to co-produce cyclohexanol and ethanol. The method has the following characteristics that 1)the esterification reaction and the hydrogenation reaction of acid and ester have high selectivity, and the atom utilization rate is high; 2)the process is eco-friendly; 3) when cyclohexanol is produced, ethanol is simultaneously co-produced; and 4) the reaction rectification is employed for addition esterification, and the reaction efficiency can be obviously increased.

The invention discloses a preparation method of 1,5,2,4-dioxadithiane 2,2,4,4-tetraoxide. The preparation method comprises a sulfonation reaction and a dehydration condensation reaction, wherein in the sulfonation reaction, methanesulfonic acid and a sulfonating agent are subjected to the sulfonation reaction, and methylene disulfonic acid is obtained; in the dehydration condensation reaction, methylene disulfonic acid prepared by the sulfonation reaction and a formaldehyde compound are dissolved in an organic solvent and subjected to the dehydration condensation reaction in the presence of adehydrating agent, a crude product of 1,5,2,4-dioxadithiane 2,2,4,4-tetraoxide is produced and added to water to be washed, and a refined product of 1,5,2,4-dioxadithiane 2,2,4,4-tetraoxide is obtained after drying. According to the preparation method of 1,5,2,4-dioxadithiane 2,2,4,4-tetraoxide, the traditional method for obtaining intermediate methylene disulfonic acid from sodium methylene disulfonate as a raw material by precipitation, acidification and dehydration is abandoned, and methylene disulfonic acid is directly obtained from methanesulfonic acid by sulfonation. The method has simple preparation process, high atom utilization rate, little three-waste and high yield.

The invention discloses a preparation method for copper and aluminium hydrotalcite. The preparation method comprises the following steps of: (1) weighing a copper source and aluminium chloride according to a 2:1 molar ratio of Cu:Al, wherein the copper source is copper oxide or copper hydroxide, dissolving the copper oxide or copper hydroxide and the aluminium chloride in deionized water to be prepared into a mixed liquor in a reaction vessel, heating and stirring the mixed liquor at the constant temperature of 30-40 DEG C till all the copper oxide or copper hydroxide is dissolved, i.e. the color of the solution becomes blue; (2) adjusting the pH value of the solution obtained in the step (1), leading the pH value of the solution not to be higher than 8, and continuously reacting for 2-4h at the temperature of 30-40 DEG C; (3) crystallizing the slurry reacted in the step (2) at the constant temperature of 30-40 DEG C; and (4) filtering, washing, drying and grinding reaction liquid crystallized in the step (3) to obtain the copper and aluminium hydrotalcite. The preparation method has the advantages that used raw materials are low in cost and easily obtained, the conversion rate of atoms is high, and the industrialization cost can be reduced.

The invention discloses a preparation method for a highly-dispersed supported catalyst. The preparation method comprises the following steps: adding tannic acid and a carrier into an active metal precursor solution, adjusting a pH value of an obtained solution to 8 to 11, carrying out a reaction for 1 to 3 h, and carrying out filtering, drying and reducing so as to obtain the highly-dispersed supported catalyst. Due to the chelating and stabilizing actions of the tannic acid, the universality of the carrier is high, and an oxide carrier with defects is no longer limited. The above-mentioned method is simple and effective and has easily-available raw materials, low cost and important industrial application prospects. The invention also discloses the highly-dispersed supported catalyst prepared by using the above-mentioned method provided by the invention. The highly-dispersed supported catalyst has high active metal dispersity and high atom utilization rate. The invention also disclosesan application of the highly-dispersed supported catalyst in a hydroformylation reaction of olefin and a hydroesterification reaction of unsaturated hydrocarbon. The highly-dispersed supported catalyst provided by the invention has high catalytic efficiency and good selectivity; and compared with a conventional homogeneous catalyst, the highly-dispersed supported catalyst provided by the invention is easy to be separated from a hydroformylation reaction system and a hydroesterification reaction system, so the cost of recovery is reduced.

The invention discloses a hierarchical-pore titanium silicon molecular sieve catalyst synthesized with the assistance of an aerosol and a preparation method of titanium silicon molecular sieve catalyst, and the titanium silicon molecular sieve catalyst is applied to the catalytic oxidation reaction of cyclohexene. The silicon molecular sieve catalyst is a hierarchical-pore titanium silicon molecular sieve synthesized through an aerosol method, is spherical, contains TS-1 nanometer crystals with MFI micropore structures, and is covered with a porous titanium silicon material. The catalyst can adopt hydrogen peroxide as an oxidant to perform catalytic oxidation on the cyclohexene to synthesize cyclohexene oxide, cyclohexanediol, cyclohexenone and cyclohexanol. The titanium silicon molecular sieve catalyst has the advantages that the preparation process is simple and continuous, the synthesis period is short, the atom utilization ratio is high, the titanium distribution is uniform, and the reaction can be magnified according to a certain ratio. The titanium silicon molecular sieve catalyst provided by the invention has the characteristics of mild reaction conditions, high activity and selectivity, small using amount, and easy recycling.

The invention provides a method for preparing ibuprofen. The method comprises: taking isobutyl-benzene as raw material, obtaining 4-isobutyl acetophenone by Friedel-Crafts reaction, obtaining 2-(4-isobutyl phenyl group)-1, 2-propylene oxide by epoxidation, obtaining 1-(4-isobutyl phenyl group) propionaldehyde through intramolecular rearrangement in the presence of Lewis acid catalysis, and obtaining the ibuprofen by oxidation of hydrogen peroxide. The preparation method has the advantages of nonuse of noble metal catalyst, low-priced material, simple process, mild reaction condition, high yield and little amount of the three wastes, and solvent used in the method meets industrialized requirements.

The invention relates to a method for coproducing cyclohexanol and ethanol, which comprises the following steps: carrying out addition esterification reaction on acetic acid and cyclohexene by using reaction rectification to prepare cyclohexyl acetate; and hydrogenating the cyclohexyl acetate to coproduce the cyclohexanol and ethanol. The method can be used for coproducing the cyclohexanol and ethanol at high efficiency and low cost.

The invention discloses a method for preparing modified oil-absorptive resin immobilized with cyclodextrin molecules. The method comprises the following steps: modifying hydroxyls of cyclodextrin molecules by taking cyclodextrin molecules, and acryloyl chloride or other acylation reagents as raw mateials in the presence of an organic base and taking an organic solvent or an organic base as a reaction medium, so as to synthesize 6-acryloyl cyclodextrin; dissolving CD-6-A in an aqueous solution under the ultrasonic action, sequentially adding a monomer, an initiator, a cross-linking agent and a pore-foaming agent into the aqueous solution, carrying out a suspension polymerization reaction to obtain the modified oil-absorptive resin, and drying under reduced pressure, thereby obtaining the product. The adsorbing capacity of the modified oil-absorptive resin containing the cyclodextrin molecules on methylbenzene is close to 45g / g, the adsorbing capacity on trichloromethane reaches 80g / g, and the resin has a very obvious effect of cleaning floating oil on the water surface. The modified oil-absorptive resin disclosed by the invention has the advantages that the preparation process is simple, the production cost is low, the adsorbing capacity is large, the oil absorption efficiency is high, the rein can be repeatedly used, and the adsorption-desorption process is simple, green and environment-friendly.

The invention provides a co-producing method and a device for cyclohexanol and ethanol. Benzene is employed as a starting material and the cyclohexanol and the ethanol are co-produced by a selective hydrogenation reaction of benzene, an additive esterification reaction of cyclohexene and a hydrogenation reaction of cyclohexyl acetate. The invention also provides a device for achieving the method. The co-producing method is characterized in that: (1) both of the esterification reaction and the ester hydrogenation reaction are greatly high in selectivity with an atom utilization rate being greatly high; (2) the producing process is environment friendly; (3) the cyclohexanol and the ethanol are co-produced; (4) the additive esterification reaction is carried out in a manner of reactive distillation, so that not only is the reaction efficiency significantly increased but also the extractive rectification separating process is simplified.

The invention relates to a CuAu bimetallic catalyst, and a preparation method and application of the CuAu bimetallic catalyst. The preparation method comprises the steps: dissolving a cuprum source and an aurum source in water simultaneously, adding ammonia water to form a metal complex, adding a mesoporous silicon molecular sieve as a carrier, heating to remove ammonia by evaporation after regulating pH (potential of hydrogen), and performing subsequent roasting and reduction activation to form the CuAu bimetallic catalyst. According to the method, Cu and Au ingredients are simultaneously loaded on the carrier by one step by an ammonia evaporation method; the Cu and Au active ingredients are dispersed highly; the CuAu bimetallic catalyst with higher activity is obtained; the catalytic efficiency is improved; and a novel means is provided for preparing the high activity loaded CuAu bimetallic catalyst. The catalyst is applied to a reaction of ethylene carbonate catalytic hydrogenation for cogeneration of methanol and glycol; a conversion rate of ethylene carbonate can reach 100%; the selectivity of glycol can reach 100%; the selectivity of methanol can reach above 70%; and the catalyst shows an excellent catalytic performance.

The invention provides a method for producing cyclohexanol, which is characterized in that benzene is taken as an initial raw material, selective hydrogenation through benzene, addition esterification of cyclohexene, and hydrogenation of acetate and cyclohexyl acetate are carried out to produce cyclohexanol, and can co-produce cyclohexanol and ethanol. The method has the following characteristics that 1)the esterification reaction and the hydrogenation reaction have high selectivity, and the atom utilization rate is high; 2)the process is eco-friendly; and 3) when cyclohexanol is produced, ethanol is simultaneously co-produced.

The invention provides a nano-composite catalyst and a preparation method thereof, belongs to the technical field of catalyzing, and solves the problem that the conventional load nano-composite oxide catalyst is low in nano-composite degree, and poor in catalyzing performance. The nano-composite catalyst is obtained by the flowing steps based on the condition that a surface-active agent is not used: firstly, reducing composite oxide crystal lattices or first metal ions mixed in the crystal lattices so as to obtain nano-metal granules containing first metal; and then introducing second metal into the surface of the first metal by Galvanic substitution reaction so as to obtain the nano-composite catalyst. Compared with the conventional catalyst, the nano-composite catalyst has more efficient catalyzing performance when being used for catalytic reaction of VOC (volatile organic compound) removal, automobile tail gas purification, formaldehyde removal, methane combustion, hydrogenation, hydrogenolysis, ammonia synthesis, ammonia decomposition, hydrocarbon synthesis, hydroformylation and the like.

The invention discloses a method for effectively preparing cylopropyl ethylnen as shown in the formula (I). The method comprises the steps that firstly, cylopropyl methyl ketone shown in the formula (II) is taken as a raw material and fully reacts in an organic solvent under the effect of phosphorus pentachloride and a catalyst, a reaction solution is subjected to reduced pressure distillation to obtain 1,1-dichloro-1-cylopropyl ethane as shown in the formula (III), an elimination reaction is then carried out under the effect of alkali, and a reaction solution is subjected to rectification and purification to obtain the product cylopropyl ethylnen. The method for effectively preparing the cylopropyl ethylnen has the advantages of being mild in reaction condition, high in yield, low in cost, little in three-waste and the like, and is suitable for industrial production.

The invention relates to the technical field of electrocatalysis, and discloses a monatomic iron-sulfur-nitrogen co-doped carbon aerogel electrocatalyst and a preparation method and application thereof. Iron in the carbon aerogel electrocatalyst is dispersed in sulfur-nitrogen co-doped carbon aerogel in a monatomic form, and the content of iron atoms in the electrocatalyst is 0.1-1wt%, the contentof sulfur atoms is 2-6wt%, and the content of nitrogen atoms is 2-10wt%; the specific surface area of the carbon aerogel electrocatalyst is 150-500 m < 2 > g <-1 >, the pore volume is 0.01-0.1 cm < 3> g <-1 >, and the pore size is 2-10 nm. Urea is dissolved, and then carrageenan and ferric nitrate are added until carrageenan and ferric nitrate are completely dissolved; the aerogel formed by freeze drying of the obtained mixed solution is calcined and subjected to acid treatment to obtain the electrocatalyst, and the electrocatalyst can be used for catalyzing nitrogen to be reduced into ammonia and zinc-nitrogen batteries and has the advantages of being high in catalytic activity, simple in preparation method, easy to operate and low in cost.

The invention relates to an N-rGO loaded copper-nickel bimetallic monatomic catalyst as well as a preparation and application thereof. The catalyst comprises a carrier N-rGO and copper and nickel which are loaded on the carrier and have the radius smaller than that of the carrier, and the preparation method comprises the following steps of 1) mixing graphene and hydrochloric acid, and then addinganiline; 2) adding a (NH4) 2S2O8 solution, mixing, filtering, drying and roasting to obtain the N-rGO; 3) adding the N-rGO into water, and adding a Na2CO3 solution to obtain a second turbid liquid; 4)mixing the mixed aqueous solution of copper nitrate and nickel nitrate with the polyvinyl alcohol aqueous solution to obtain a mixed solution; and 5) adding the mixed solution into the second turbidliquid, and sequentially mixing, filtering, drying and roasting to obtain the catalyst. The catalyst is used for the selective C-S bond cleavage reaction of 4, 6-DMDBT in the catalytic cracking fuel.Compared with the prior art, the catalyst disclosed by the invention is high in reaction activity, simple in preparation process and outstanding in desulfurization effect on the compounds, such as 4,6-DMDBT, etc., in the fuel oil.