The invention discloses a de-massing method of position advertising service based on a regional strategy and a system. The method comprises the following steps: analyzing the user number in the corresponding region according to the data request of the position advertising service, checking the region state of the region corresponding to the current data request, obtaining the user attribute of the user number in the corresponding region, configuring the regional strategy of the region corresponding to the user attribute, filtering position advertising information according to the regional strategy, and sending to the user number in the corresponding region. Because of taking over a current wireless mobile communication network and combining the region position of the user, the statistical characteristic of the user, the group demand characteristics and other information, the invention expands the position advertising marketing of the service system with target orientation, reduces the release of useless investments, lightens the impact of the service system to an information downlink system network, improves the operating efficiency of the service system, increases income for the operators, saves social resources, and meets the information requirements of social individual.