The present invention discloses one kind of Chinese medicine preparation for antagonizing bacteria and viruses of pig and improving pork quality and its preparation process, and belongs to the field of medicine technology. The Chinese medicine preparation is prepared with 12 kinds of Chinese medicinal materials, including cablin pochouli herb, elsholtzia, skullcap root, white atractylodes rhizome, honeysuckle stem, etc, and through sorting, mixing, drying, grinding into powder, mixing and packing. It is used to replace antibiotic and can regulate the immunity of pig in different growth stages, prevent and treat diarrhea, pig flu and plague, promote growth of pig and raise pork quality.