7results about How to "Safe" patented technology

The application provides application of tetrahydropalmatine in preparation of a medicine for treating acute and chronic contact dermatitis. Experiments show that tetrahydropalmatine can significantly inhibit redness, desquamation and ear swelling of acute and chronic contact dermatitis, reduce itching, inhibit epidermal thickening and inflammatory infiltration. The mechanism of action includes double inhibition of TSLP and TNF-alpha protein levels, and recovery of EDEM3 expression by directly combining EDEM3 protein (KD=3.69±0.21 muM), inhibition of endoplasmic reticulum stress, and thus down-regulation of epithelial alarm substances IL25, IL33 and TSLP. The effect of tetrahydropalmatine disappears after EDEM3 is silenced, confirming that EDEM3 is a functional target protein. In addition, tetrahydropalmatine is also effective for non-histamine-dependent allergic contact dermatitis, and has no side effects such as skin atrophy and weight loss, and the safety is better than that of dexamethasone. The application also relates to similar application of tetrahydropalmatine and cortex phellodendri extract. The application provides a safe, effective and mechanism-confirmed new type of therapeutic drug for contact dermatitis.

The present disclosure provides a safe conductive coating slurry, a composite current collector and a preparation method thereof, and a battery, and belongs to the field of battery materials. The safe conductive coating slurry for the composite current collector comprises, in terms of mass fraction, 15-30 parts of a main material, the main material comprising microcrystalline glass; 10-30 parts of a binder; 10-20 parts of a solvent; 0.5-2 parts of a dispersing agent; 0.5-1 part of a wetting agent; and 0.5-1 part of a leveling agent. The coating slurry of the present disclosure comprises microcrystalline glass, which can simultaneously play the roles of a conductive coating and a safe coating by only coating one layer of coating, thereby simplifying the preparation process and the coating process; when combined with an electrode active material, the coating slurry does not cause the electrode active material to fall off; and the safe conductive coating has no cracking phenomenon. The technical problems of the prior art, such as the complexity of the slurry preparation process and the coating process when the two-layer structure of the conductive coating and the safe coating is coated on the composite current collector, the easy falling off of the electrode active material when combined with the electrode active material, and the easy cracking of the conductive coating, are avoided.

The present application relates to the field of locator, propose a kind of pet locator's binding method and locator binding device, locator binding device includes base, mechanical arm and main controller, by using the pressure sensor on base receives pet standing information, main controller controls the contraction and binding of binding belt of mechanical arm, solve the problem that pet locator installation is easy to fall off in prior art, installation is not firm, achieved the firmness of improvement pet positioning installation, improve the automation level and portability of pet locator binding, with the beneficial effects of high security and practicality.

The utility model relates to the technical field of coating barrel transfer, and discloses a coating barrel transfer device which comprises a platform plate, a U-shaped plate is fixedly connected to the top of the platform plate, a material storage mechanism is arranged on the U-shaped plate and comprises a main body plate, the main body plate is arranged on the top of the platform plate, a threaded rod is rotationally connected to the inner side of the U-shaped plate, and the threaded rod is arranged on the top of the platform plate. One end of the threaded rod is rotationally connected with the top of the platform plate. Through the design of the material storage mechanism, the coating barrels are placed and stored in different placing frames, then the platform plate is controlled to move to transfer the coating barrels, during loading and unloading in the transfer process, a motor works to drive a threaded rod to rotate, the threaded rod is promoted to drive a main body plate to ascend and descend, and therefore when the coating barrels are loaded and unloaded, the placing frames are controlled to descend to the low position, and the coating barrels are transferred. And compared with the operation that the coating barrel needs to be manually loaded and unloaded to the high position, more physical strength is saved, and safety is achieved.

This invention provides a fluororubber using naphthylhydrazone imide as a crosslinking agent, its preparation method, and its applications, belonging to the field of chemical materials. It is prepared from raw materials comprising the following parts by weight: 100 parts of fluororubber raw rubber, 10-30 parts of reinforcing filler, 0-3 parts of internal release agent, 5-20 parts of acid scavenger, 0.5-2 parts of naphthylhydrazone imide, and 0.5-1.5 parts of accelerator; wherein the naphthylhydrazone imide is a monohydroxy-substituted naphthylhydrazone. This invention uses naphthylhydrazone imide to replace bisphenol AF as the crosslinking agent in the fluororubber system. When its addition amount is only half that of bisphenol AF, a fluororubber with the same excellent mechanical properties, aging properties, and oil resistance as the bisphenol AF system can be obtained. The fluororubber of this invention is legal, compliant, safe, and possesses excellent comprehensive performance, providing a feasible alternative for the application of fluororubber in high-end environmentally friendly fields.

The application discloses a kind of data storage method and system based on object chain, which comprises: using N nodes to store data and text;N nodes are linked to form M string chain under the guarantee of security guarantee mechanism;M string chain freely constitutes X object unit;X object unit is linked to form block chain by control library firmware, realize the storage of multiple data and text;The system makes the above-mentioned method carry out data storage and management;System includes support layer, functional layer and interface layer;Wherein, support layer includes: directory service module;Functional layer includes: authentication service module, identity management module, authorization management module, role management module, resource management module and configuration management module;Interface layer includes: API interface module, Web service module and management tool module;Different functional components can be connected through API interface module, can adapt to various different platforms, and the performance is stable and reliable;And data storage efficiency and security are very high, and storage is not limited.

The invention belongs to the technical field of water conservancy and transportation engineering maintenance, and particularly relates to a ship lock concrete surface repairing coating in a seawater soaking environment and a construction method of the ship lock concrete surface repairing coating. Comprising a permeation anchoring bottom coating, a stress buffering middle coating and a super-weather-resistant protective surface coating which are sequentially arranged from inside to outside, and the permeation anchoring bottom coating is a bi-component epoxy-biomineralization composite system. The construction method of the ship lock concrete surface repairing coating comprises the steps that a base plane is diagnosed and cleaned; constructing a negative pressure microenvironment; carrying out in-situ vacuum dehydration and exclusion; negative-pressure prime coat leading-in is carried out; performing controlled ventilation and re-pressing permeation; and constructing a multi-layer system. According to the method, capillary water wedge resistance can be overcome under the condition that a dry base plane does not need to be stopped for a long time, deep penetration and high-strength anchoring of a repairing material to concrete microcracks are achieved, and the chloride ion penetration resistance and durability of a ship lock structure are greatly improved.