160 results about "Control subjects" patented technology

The methods described herein enable the evaluation of compounds on subjects to assess their therapeutic efficacy or toxic effects. The target of analysis is the underlying biochemical process or processes (i.e., metabolic process) thought to be involved in disease pathogenesis. Molecular flux rates within the one or more biochemical processes serve as biomarkers and are quantitated and compared with the molecular flux rates (i.e., biomarker) from control subjects (i.e., subjects not exposed to the compounds). Any change in the biomarker in the subject relative to the biomarker in the control subject provides the necessary information to evaluate therapeutic efficacy of an administered drug or a toxic effect and to develop the compound further if desired. In one aspect of the invention, stable isotope-labeled substrate molecules are administered to a subject and the label is incorporated into targeted molecules in a manner that reveals molecular flux rates through one or more metabolic pathways of interest. By this method, a comparison between subjects and control subjects reveals the effects of the chemical entity or entities on the biomarkers. This, in turn, allows for the identification of potential therapeutic uses or toxicities of the compound. Combinations of compounds can also be systematically evaluated for complementary, synergistic, or antagonistic actions on the metabolic pathways of interest, using the methods of the present invention as a strategy for identifying and confirming novel therapeutic or toxic combinations of compounds.

A heat exchanger for use in controlling subject's body temperature during a medical procedure comprises a flexible garment adapted for enveloping portions of the subject's body surface with dedicated sections for enveloping different body parts. Defined within the garment is a continuous, fluid tight space, wherein a flow path for heat-control fluid is defined between fluid inlet and fluid outlet. The inner faces of the garment's internal and external layers are made of a heat-weldable material and are point-welded to one another at a plurality of locations throughout the garment with a distance between two adjacent points being between about 8 to about 20 mm.

A control system includes a basic control command operating unit, a fuel data storage unit, a running results database for storing past running results values of a control subject, a data creating unit configured to calculate a distance between data of the past running results values and the data sets and determining data set in which a distance between data becomes minimum, a modeling unit configured to model a relationship between operation parameters of a combustion apparatus and components in combustion gas of the combustion apparatus by using the data set determined by the data creating unit and a correcting unit for calculating combustion apparatus operation parameters with which components having a better condition than that of the components in a current gas are provided by using a model of the modeling unit and correcting operation command values of the basic control command operating unit by calculated operation parameters.

An OES measuring unit outputs a spectroscopically measured value for each step at the end of or immediately after each step. A CD estimating unit obtains an estimated CD value for each step using a CD estimation model and a spectroscopically measured value received from an estimation model storage unit. In the next step, a process control unit uses an estimated CD value for the previous step received from the CD estimating unit, in addition to a process condition setting value for the next step received from a recipe storage unit and a process control model for the next step received from a control model storage unit, for automatic control of the control subject

The invention includes a method to identify a method to enhance survival of a subject that has been exposed to a biological insult such as an ionizing radiation dose of LD_50/30 by treating the exposed subject with a test compound an optically comparing the results to that obtained using control subjects that had been treated with 3β,17β-dihydroxyandrost-5-ene or other disclosed compounds.

A means of measuring and monitoring skeletal growth rate using a plasma analyte, amino-terminal C-type natriuretic peptide (NT-CNP). Plasma NT-CNP concentrations reflect the potential for further growth of the immature skeleton. Measurement of plasma NT-CNP in a subject, when related to the mean of an appropriate age and gender matched set of control subjects, provides an index of the severity of a growth disorder not otherwise available and facilitates diagnosis in children with undetected osteo-chondrodysplasias or other intrinsic disorders of the growth plate. The invention also provides a means of detecting and monitoring potentially harmful effects of drugs and other factors on skeletal growth long before they are evident using current methods in clinical practice.

The invention discloses an intelligent kitchen host and a work method and a control method of the intelligent kitchen host: obtaining device information of different kitchen devices, wherein the device information includes device function information, device parameter information, state monitoring interface information, control interface information and/or device identification information representing kitchen device types; and according to different kitchen device information, in a cooking control program set after a cooking control subject is analyzed, selecting a cooking control program which matches the device information so as to coordinate work of different kitchen devices and complete the whole cooking process and thus a problem of transition from a traditional kitchen to an intelligent kitchen is solved and the intelligent kitchen host has flexible control method and applicability.

There is provided a control apparatus including a function of generating an operation signal applied to a control subject and a model that simulates characteristics of the control subject, a function of receiving an evaluation value signal calculated based on a measurement signal obtained by applying the operation signal to the control subject and the model, and a function of learning to generate the operation signal such that an expected value of the sum of the evaluation value signals obtained from a present state to a future state is either maximum or minimum in which the evaluation value signal calculated based on the measurement signal from the model is calculated by adding a first evaluation value obtained based on a deviation between the measurement signal obtained from the model and a setpoint value, and a second evaluation value obtained based on a difference in characteristics between the model and the control subject.

The invention discloses a visual point burying method for a cross-platform mobile terminal. The method comprises the steps that control tree related information sent to a current interactive interfaceof a server is refreshed after a client establishes a connection with the server; the server synchronously updates a rendering interface according to the received information, and a user performs visual point burying selection operation on a control in the server; a binding condition of the control is tested, the server sends point burying information to the client, and the client confirms the control specified in the obtained point burying information and performs binding; the test of the bound control is triggered in the client, event information of the control is triggered and sent to theserver, and after the test is passed, the server performs deployment operation on the control subjected to point burying and selection. A point burying dimension self-definition function is added; thesupport of point burying of HTML elements is added; the interactive interface control is universally used for various self-defined client interactive interfaces; and for the webpage control, a visualcode injection point burying function and a similar element point burying function are supported.

A control device and method in which, even when a road deviation operation is performed continuously near a road boundary where sidewalk/road separating blocks are discontinuously lined up, discontinuity does not occur in the control input, and unwanted vehicle behavior does not occur. The sizes of obstacles present around a host vehicle, as well as their relative positions and relative speeds with respect to the host vehicle are detected 500. A pair to be linked is determined from among the plurality of detected obstacles 501. An obstacle link length that serves as a determination criterion for virtual linking is set 502. Whether or not to perform virtual linking is determined based on the determination criterion 503. A gap position interpolation process 504 is performed with respect to the pair for which it has been determined that virtual linking is to be performed. A search is performed as to whether or not there exists a control subject for which collision is to be avoided 505. A yaw moment for avoiding an obstacle is calculated based on position information of the avoidance control subject 506.

This invention relates to a simultaneous control applied in magnetic suspension switch magnetic resistance motor, which comprises the following steps: adopting extensive flow control inverter, wherein the controlled magnetic suspension switch magnetism motor forms compound controlled subject; forming neural net athwart by static neural net and integral device through formula study; connecting neutral net with the compound controlled subject then compounding into two radius direction position sub system to forming anti-linear system; making the linear loop controller to the false linear system according to the linear system design; finally connecting the neural net with the linear loop controller and with the flow controlled inverter to form neural net decoupling controller.

The present invention relates to a control program, a controller, and a boiler system that are related to a boiler group including a plurality of boilers controlled in combustion at stepwise combustion positions. It is well suitable, in a control program for conducting control on a boiler system that includes a boiler group having a plurality of boilers which can be controlled in combustion quantity at stepwise combustion positions and in which at least one of the combustion positions is assumed to be a high-efficiency combustion position and that is configured to be controlled in combustion based on an increase/decrease in desired loads, that in the case of increasing a quantity of combustion in the boiler group, after a high-efficiency combustion shift signal that makes the shift to the high-efficiency combustion position is output to all of the boilers subject to high-efficiency control by which control is conducted on the basis of combustion at the high-efficiency combustion position, a control signal may be output that makes the shift to a higher combustion position than the high-efficiency combustion positions for any one of the high-efficiency control subject boilers.

In order to provide an MRI apparatus that can efficiently approximate a specific absorption rate or a magnetic field variation rate per unit time of a magnetic flux density to a target value, the present invention is characterized in that suggestions of imaging parameters related to a control subject and change directions of the imaging parameters when the control subject is input based on an input operation and that the control unit further calculates values of the selected control subjects based on the changed imaging parameter values.

The present invention exploits the discovery that amounts of uracil and thymine metabolites, especially β-aminoisobutyric acid, in various bodily fluids, especially urine, are correlated with the occurrence of epilepsy when compared to matched control subjects. Analytical and diagnostic protocols, including a novel high performance liquid chromatography system, for use in the invention are disclosed.

In adjustment of the control parameters of a magnetic suspension system, an object of the present invention is to provide a technique for adjusting the control parameters to optimum values automatically by employing the iterative feedback tuning method, without increasing the complexity of the program, the amount of calculation and the overall size of the system, and still reducing the amount of calculation required for calculation of the safety margin (gain margin and phase margin). In a method of automatic adjustment of control parameters according to the invention, when applying the iterative feedback tuning method to a feedback control system for a magnetic suspension system, only those control parameters that have a significant effect on the control performance of the system are selectively adopted/discarded from among control parameters so that the control parameters are guided to optimum values to obtain a response waveform desired by a designer directly from input/output data of a control subject.

This invention relates to a spot intelligent unit and its operation method supporting industry communication network agreement, which comprises control unit and communication port module. The communication port module realizes the MODBUS/TCP industry Ethernet agreement or DeviceNet spot bus agreement or Profibus-DP spot bus agreement. The control unit has a microprocessor connected with A/D converter, D/A converter through light couple device, wherein its switch input, output and A/D converter and D/A converter are connected with the control subject.

A characteristic control device which is provided with a basic control module which determines the amount of control used to control the output of a control subject based on predetermined input data and control parameters which relate output to the control subject to the input data and which controls the characteristics of the control parameters, a characteristic storage mechanism for storing the basic control parameters, and a characteristic automatic modification mechanism which determines, in accordance with predetermined conditions, and automatically modifies, the control parameters which are applied to the basic control module based on the basic control parameters stored in the characteristic storage mechanism and the input data.

The invention relates to an airplane seat having an audio system for playing back audio data, wherein the audio system comprises a volume controller and/or a noise compensation controller, a head rest element having a loudspeaker element that can be swiveled at a swivel angle α, and wherein the volume and/or the degree of noise compensation is controlled subject to the swivel angle α.