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42 results about "Phytoalexin" patented technology

Phytoalexins are antimicrobial and often antioxidative substances synthesized de novo by plants that accumulate rapidly at areas of pathogen infection. They are broad spectrum inhibitors and are chemically diverse with different types characteristic of particular plant species. Phytoalexins tend to fall into several classes including terpenoids, glycosteroids and alkaloids; however, researchers often find it convenient to extend the definition to include all phytochemicals that are part of the plant's defensive arsenal.

Antiestrogenic glyceollins suppress human breast and ovarian carcinoma proliferation and tumorigenesis

InactiveUS20060246162A1Preventing minimizing development growthOrganic active ingredientsBiocideStress inducedPhytochemical
The flavonoid family of phytochemicals, particularly those derived from soy, has received attention regarding their hormonal activity and their effects on human health and disease. The types and amounts of these compounds in soy and other plants are controlled by both constitutive expression and stress-induced biosynthesis. The health benefits of soy may therefore be dependent upon the amounts of the various hormonally active phytochemicals present. We have identified increased biosynthesis of the isoflavonoid phytoalexin compounds, Glyceollins I, II and III, in soy plants grown under stressed conditions (elicited soy), which exhibit marked anti-estrogenic effects on ER function. Here we demonstrate that specific glyceollins, isolated from elicited soy, displayed anti-estrogenic activity, suppressing basal and estrogen stimulated colony formation of ER-positive estrogen dependent breast cancer cells and inhibiting ER-dependent gene expression of progesterone receptor (PgR) and stromal derived factor-1 (SDF1/CXCL12). Examining the effects of glyceollin on in vivo tumor formation/growth we demonstrate the ability of glyceollins to significantly suppress basal and estrogen-stimulated tumor growth of ER-positive MCF-7 breast and BG-1 ovarian carcinoma cells in ovariectomized female nude mice. We further demonstrate that the effects of glyceollins on suppression of tumor growth correlate with inhibition of estrogen stimulated PgR expression. In contrast to the uterotropic activity of tamoxifen the glyceollins displayed no uterine agonist activity. The Glyceollin (I-III) compounds may represent an important component of the health effects of soy as well as represent novel anti-estrogens useful in the prevention or treatment of breast and ovarian carcinoma.
Owner:UNITED STATES OF AMERICA AS REPRESENTED BY THE SEC OF AGRI THE

Antiestrogenic glyceollins suppress human breast and ovarian carcinoma proliferation and tumorigenesis

InactiveUS20080200537A1Preventing minimizing development growthBiocideAnimal repellantsDiseaseStress induced
The flavonoid family of phytochemicals, particularly those derived from soy, has received attention regarding their hormonal activity and their effects on human health and disease. The types and amounts of these compounds in soy and other plants are controlled by both constitutive expression and stress-induced biosynthesis. The health benefits of soy may therefore be dependent upon the amounts of the various hormonally active phytochemicals present. We have identified increased biosynthesis of the isoflavonoid phytoalexin compounds, Glyceollins I, II and III, in soy plants grown under stressed conditions (elicited soy), which exhibit marked anti-estrogenic effects on ER function. Here we demonstrate that specific glyceollins, isolated from elicited soy, displayed anti-estrogenic activity, suppressing basal and estrogen stimulated colony formation of ER-positive estrogen dependent breast cancer cells and inhibiting ER-dependent gene expression of progesterone receptor (PgR) and stromal derived factor-1 (SDF1 / CXCL12). Examining the effects of glyceollin on in vivo tumor formation / growth we demonstrate the ability of glyceollins to significantly suppress basal and estrogen-stimulated tumor growth of ER-positive MCF-7 breast and BG-1 ovarian carcinoma cells in ovariectomized female nude mice. We further demonstrate that the effects of glyceollins on suppression of tumor growth correlate with inhibition of estrogen stimulated PgR expression. In contrast to the uterotropic activity of tamoxifen the glyceollins displayed no uterine agonist activity. The Glyceollin (I-III) compounds may represent an important component of the health effects of soy as well as represent novel anti-estrogens useful in the prevention or treatment of breast and ovarian carcinoma.
Owner:UNITED STATES OF AMERICA +1

Kiwi fruit winter frost damage prevention method

InactiveCN103931459APrevention of dehydration and crackingStay safe through winterClimate change adaptationCultivating equipmentsActinidiaKiwi fruit
The invention discloses a kiwi fruit winter frost damage prevention method. The method includes the steps that foliage fertilizer is applied in October to November at the late growth stage of kiwi fruits, and monopotassium phosphate or phytoalexin or fertility micro element fertilizer is sprayed; after winter comes, more fertilizer is applied, pits at kiwi fruit trunks close to roots are expanded, and rotten manure or pig and cattle pen manure or organic biological fertilizer is applied; the kiwi fruit trunks close to the roots are covered, the kiwi fruit trunks close to the roots are covered with rice straw, straw and weeds in winter, or the kiwi fruit trunks close to the roots are covered with a mulching film; before frost approaches, the mulching film or straw mats cover branches of a kiwi fruit shed frame. The kiwi fruit winter frost damage prevention method has the advantages that tree vigor can be improved through fertilization application, and the stress resistance of the kiwi fruits is improved; the soil temperature can be raised by covering the kiwi fruit trunks close to the roots, so that root systems are protected; by covering the branches of the kiwi fruit shed frame, water loss and cracking of the branches can be prevented. It has been proved that the kiwi fruits can be protected to survive the winter safely.
Owner:蒋平友
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