9 results about "Nicotine delivery" patented technology

A nicotine delivery device (200) for generating a mist containing nicotine for inhalation by a user. The device comprises a mist generator device (201) and a driver device (202). The driver device (202) is configured to drive the mist generator device (201) at an optimum frequency to maximise the efficiency of mist generation by the mist generator device (201).

Nicotine-containing formulations for electric / electronic nicotine delivery systems are disclosed, containing both nicotine at relatively much higher concentrations, typically at least 25% by weight of total formulation weight, w / w, and in many cases as much as 40-50% w / w, than is typical for conventional nicotine containing formulations, which only contain about 2-4% w / w nicotine. The formulations also include a biologically and pharmaceutically acceptable mono- or di-carboxylic organic acid, such as benzoic acid, salicylic acid and most preferably lactic acid also at relatively high w / w concentrations. One or more nicotine salts may be created and be extant within the formulations, which not only mitigates against the loss of nicotine to the atmosphere through natural volatility and evaporation, but also markedly increases the surface energy of the formulations created, and the globules of formulations deposited on a heating substrate are much more cohesive and much less likely to migrate through wetting over the substrate.

This invention discloses a nicotine delivery control method, system, electronic device, and storage medium. The method includes: acquiring baseline physiological signal data of a user in a resting state via a biosignal acquisition module; establishing an individual physiological baseline value for the user based on the baseline physiological signal data via an edge computing processing module; acquiring the user's current physiological signal data in real time via the biosignal acquisition module during user use; determining the user's current emotional state based on the current physiological signal data and the individual physiological baseline value via the edge computing processing module, and generating a heating strategy instruction corresponding to the current emotional state; and receiving and executing the heating strategy instruction via a dynamic heating execution module to adjust the heating method of the cigarette, thereby achieving nicotine delivery control. The technical solution of this invention achieves personalized nicotine delivery by identifying the user's emotional state during use and dynamically adjusting the nicotine delivery rate accordingly.

The Invention relates to an oral nicotine delivery product containing a composition enclosed in a water-insoluble pouch, said pouch being permeable to saliva and to dissolved compounds of the composition, the composition comprising a nicotine source and cellulose or a cellulose derivative, the cellulose or cellulose derivative being in granular form. The invention further relates to a method for preparing the product for oral administration of nicotine.

The invention discloses a nicotine dental strip and a preparation method thereof. The nicotine dental strip has a three-dimensional shape matched with the shape of teeth. The nicotine tooth paste comprises a release film layer, a gel layer and a protective layer which are stacked in the thickness direction, the gel layer includes a nicotine source. According to the utility model, the nicotine tooth paste is directly and fixedly adhered to the surface of the tooth, especially the back side of the tooth, so that the problems that the nicotine buccal product cannot be fixed in the oral cavity and is easy to displace, wrinkle or fall off are solved, and the foreign body sensation and mistaken swallowing risk of the nicotine product in the oral cavity are reduced; on the premise of not influencing normal diet and social contact, the nicotine delivery position is constant, the nicotine release is more stable, the flavor in the oral cavity is full and consistent, the irritation of the nicotine tooth paste to the oral cavity and the stomach is remarkably reduced, the comfort and the user acceptance are greatly improved, and consumers have better consumption experience.

The present invention relates to a smokeless article for oral delivery comprising a pouch enclosing an oral nicotine delivery (OND) formulation, the OND formulation comprising at least two pH regulators selected from the list of sodium carbonate, sodium hydroxide, calcium lactate, sodium phosphate dibasic, sodium citrate, meglumine, ammonia, ammonium carbonate, and calcium carbonate. A method of manufacturing the article and kits comprising the article are also described.

The present disclosure relates to a nicotine inhaler (100) configured to deliver vaporized nicotine without combustion. The inhaler (100) comprises a housing (105) enclosing a solution chamber containing a nicotine solution (135), a wick (130) configured to transport the solution to a piezoelectric disk (150), and a printed circuit board (PCB) (115) connected to a battery (120). The PCB (115) supplies high-frequency signals to actuate the piezoelectric disk (150), which atomizes the nicotine solution into a fine mist. A power button and recharge port (125) are configured for user activation and battery charging. The vaporized mist is guided through an outlet section (155) to a detachable spout (110) for inhalation. The device enables controlled, smoke-free nicotine delivery using ultrasonic atomization, offering a cleaner alternative to traditional methods.

A synthetic nicotine substitute for use in a variety of delivery systems, particularly in electronic nicotine delivery systems, such as atomizers, electronic cigarettes, combustion, heat-not-burn products, oral or nasal nicotine delivery systems. (S)-6-methylnicotine, also known as (S)-2-methyl-5-(1-methylpyrrolidine-2-yl) pyridine, is a derivative of nicotine, and the 6-site of the pyridine ring of the (S)-6-methylnicotine is substituted by methyl. Preliminary experimental data show that the efficacy of (S)-6-methylnicotine is about 4-5 times (by weight) of nicotine, the (S)-6-methylnicotine can take effect more quickly, and the nicotine desire can be controlled or met more effectively. The carboxylate is also applicable. The enhanced efficacy enables people to alleviate nicotine craving faster and more effectively with a lower dose, and produces a subjective satisfaction to meet the smoking addiction. This enhanced pharmacological efficacy allows for the use of smaller amounts of active ingredients compared to synthetic nicotine formulations, among other potential benefits.

FIELD: hygiene; toxicology; preventive medicine.SUBSTANCE: used for quantitative assessment of the total nicotine load in individuals using electronic nicotine delivery systems (ENDS). The average daily volume of liquid consumed, the concentration of nicotine in it, and the length of time of ENDS use in years are determined. The obtained data is processed by calculating the integral nicotine load index (INLI) in conventional units of “vape-years” using an original mathematical formula, taking into account the standard daily dose of nicotine.EFFECT: method ensures the objectification of risk stratification and increases the effectiveness of clinical observation of ENDS users through a quantitative assessment of the accumulated toxic load, taking into account the totality of the period of use and the physical and chemical parameters of the consumed liquid.1 cl, 3 ex