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1232 results about "Sample pool" patented technology

Apparatus and methods for analyzing body fluid samples

An apparatus is provided for monitoring a predetermined parameter of a patient's body fluid while infusing an infusion fluid into the patient. The apparatus comprises an infusion line and a catheter configured for insertion into a blood vessel of the patient, and a reversible infusion pump connected between a source of an infusion fluid and the infusion line and catheter. The apparatus further comprises a body fluid sensor assembly mounted in fluid communication with the infusion line and which includes a first sensor and a sample cell. The first sensor provides a signal indicative of a predetermined parameter of any fluid present in the infusion line. The sample cell is substantially transmissive to light comprising a wavelength λ. The apparatus further comprises a controller that is configured to operate the infusion pump in a forward direction so as to pump the infusion fluid through the infusion line and catheter for infusion into the patient. The controller is configured to intermittently interrupt its operating of the infusion pump in the forward direction to operate the infusion pump in a rearward direction so as to draw a body fluid sample from the patient through the catheter and infusion line. The body fluid sample drawn from the patient is disposed such that a first portion of the body fluid sample is in sensing contact with the first sensor of the body fluid sensor assembly, and a second portion of the body fluid sample is disposed within the sample cell of the body fluid sensor assembly. The controller further is configured to monitor the signal provided by the first sensor of the body fluid sensor assembly and to detect a change in the signal indicative of the arrival of the body fluid sample at the first sensor. The controller, in response to detecting the arrival of the body fluid sample at the first sensor, is configured to cease its operating of the infusion pump in the rearward direction. The signal produced by the first sensor provides an indication of a predetermined parameter of the patient's body fluid when the body fluid sample is in sensing contact with the first sensor.
Owner:OPTISCAN BIOMEDICAL

Method of modulating the transmission frequency in a real time opinion research network

A computer-implemented transmission scheme is provided to control client-server interchanges within a distributed communications network, such as a real time opinion research system. Interchanges include transmitting media streams between one or more clients to a server over a computer network, including the global Internet. A polling management unit sets and manages the transmission mode that includes event-driven and periodic interchanges. Periodic interchanges can be simultaneously or staggeredly transmitted to a sampling pool of active clients. A transmission mode unit implements the transmission scheme set by the polling management unit. A parameter selector establishes the transmission interval and transmission period which are used to trigger each communication interchange. A client assignor creates one or more sampling classes from the sampling pool by applying a sampling quotient that is generated by the parameter selector. A schedule editor produces a transmission schedule for the active clients. If more than one sampling class has been created, each sampling class would receive a separate transmission schedule for providing staggered transmissions at designated transmission intervals. The transmission schedule can include other data preparation and formatting instructions for compression, aggregation and packetization.
Owner:ZARBANA DIGITAL FUND

Apparatus and methods for analyzing body fluid samples

An apparatus is provided for monitoring a predetermined parameter of a patient's body fluid while infusing an infusion fluid into the patient. The apparatus comprises an infusion line and a catheter configured for insertion into a blood vessel of the patient, and a reversible infusion pump connected between a source of an infusion fluid and the infusion line and catheter. The apparatus further comprises a body fluid sensor assembly mounted in fluid communication with the infusion line and which includes a first sensor and a sample cell. The first sensor provides a signal indicative of a predetermined parameter of any fluid present in the infusion line. The sample cell is substantially transmissive to light comprising a wavelength B. The apparatus further comprises a controller that is configured to operate the infusion pump in a forward direction so as to pump the infusion fluid through the infusion line and catheter for infusion into the patient. The controller is configured to intermittently interrupt its operating of the infusion pump in the forward direction to operate the infusion pump in a rearward direction so as to draw a body fluid sample from the patient through the catheter and infusion line. The body fluid sample drawn from the patient is disposed such that a first portion of the body fluid sample is in sensing contact with the first sensor of the body fluid sensor assembly, and a second portion of the body fluid sample is disposed within the sample cell of the body fluid sensor assembly. The controller further is configured to monitor the signal provided by the first sensor of the body fluid sensor assembly and to detect a change in the signal indicative of the arrival of the body fluid sample at the first sensor. The controller, in response to detecting the arrival of the body fluid sample at the first sensor, is configured to cease its operating of the infusion pump in the rearward direction. The signal produced by the first sensor provides an indication of a predetermined parameter of the patient's body fluid when the body fluid sample is in sensing contact with the first sensor.
Owner:OPTISCAN BIOMEDICAL

Liquid-phase suspension biochip based on multi-optical trap encoding bead array and two-photon fluorescence detection

InactiveCN105784662AReal-time analysisSimplify the enrichment processFluorescence/phosphorescenceMicrosphereBand-pass filter
The invention provides a liquid-phase suspension biochip based on multi-optical trap encoding bead array and two-photon fluorescence detection. The liquid-phase suspension biochip has a configuration as follows: a near-infrared laser beam emitted by a near-infrared laser is expanded by a beam expanding system, is sequentially reflected by a telescope system and a dichroscope by using a holographic technology or a time-share scanning technology, and is focused into a sample pool through a high numerical aperture objective lens, to form multi-optical-trap optical tweezers; the multi-optical-trap optical tweezers capture a plurality of encoding beads enriched with objects to be detected, to form a bead array in the solution; after an infrared laser signal is filtered by a band-pass filter, a two-photon fluorescence signal from each bead is focused to an image detector by a lens and is subjected to imaging detection. The liquid-phase suspension biochip can perform real-time quantitative analysis on nucleic acids, proteins, virus particles and a plurality of objects to be detected, and has the advantages of high sensitivity, strong anti-interference ability, simultaneous determination of a plurality of components and the like.
Owner:WUHAN UNIV

Apparatus and methods for automated diffusion filtration, culturing and photometric detection and enumeration of microbiological parameters in fluid samples

A system providing non-intrusive, automated culturing and photometric detection for analyzing microbiological parameters is described. The system includes a sealed non-intrusive sample cuvette, a housing with an enclosable cover, systems for incubation and photometric detection mounted within the housing. The sample cuvette consists of a clear graduated optically transmitive container with two chambers—a culture chamber and a detection chamber, separated by a permeable membrane wall. The cuvette has an upper part and a lower part of different dimensions. The upper part is bigger in size than the lower part. The sealed top of the cuvette has two fluid inlet/outlet ports for the introduction of the sample into one chamber while when connected to a suitable vacuum device, the second chamber receives the filtered sample through the permeable membrane. The housing has a cuvette holder that is shaped to provide a very snug fit for the cuvette. When placed inside the cuvette holder the bottom of the upper part of the cuvette rests on top of the holder while the bottom part snugly fits inside the holder cavity. The housing with the enclosable cover provides a thermal chamber during simultaneous incubation and photometric enumeration of microbiological parameters. The cuvette holder accommodates a heating element and a temperature sensor. Photometric detection components comprising LEDs and detectors are placed strategically within the holder.
Owner:KANIPAYOR RAVI +1

Surface plasmon resonance imaging sensing system

The invention relates to a surface plasmon resonance imaging sensing system, which comprises a plasma resonator with isosceles triangle cross-section, wherein the plane of the bottom side of the isosceles triangle is of a sensing plane, and a layer of metal reflection film is plated on the sensing plane; a sample pool with an inlet and an outlet is arranged on the metal reflection film, and one of the planes of the two sides of equal length is used as an incident plane, and the other thereof is used as an emittance plane; a power source, a beam shaper and a polarizer are sequentially arranged on an incident light path which is vertical to the incident plane to reach the sensing plane, and an analyzer, an imaging lens group and an area array photoelectric sensor are sequentially arranged on a reflection light path generated by the sensing plane; and the area array photoelectric sensor is positioned on a focal plane of the imaging lens group and is connected with an external computer. The surface plasmon resonance imaging sensing system is characterized in that: the light source is a non-coherent light source, and a narrow-band filter is arranged between the polarizer and the incident surface. The invention can be widely used in food safety detection, pesticide residue detection, bio-molecule detection, bio-terrorist detection and other fields.
Owner:SHENZHEN INT TRAVEL HEALTHCARE CENT +1

DSC meter with visualization function

The invention discloses a differential scanning calorimeter, which is compatible with visualization and comprises a worktable, a first heat current detection part, a second heat current detection part, temperature control equipment, a temperature-recording instrument, a microscope image pickup system and an image acquisition system; wherein, the worktable is provided with a sample cell and a reference cell. The first heat current detection part is arranged in the sample cell and used for bearing samples and transmitting heat flux with the samples. The second heat current detection part is arranged in the reference cell and is used for bearing reference compound and transmitting heat flux with the reference compound. The temperate control equipment respectively controls the heating up and temperature reduction of the two heat current detection parts. The temperature-recording instrument is respectively connected with the two heat current detection parts by a thermocouple wire. The microscope image pickup system observes the microstructure of the samples by a sample observation window arranged on the sample cell and acquires and records the microstructure variation of the sample by the image acquisition system. The differential scanning calorimeter can monitor and acquires the structure variation information of the sample while measuring the heat flow when the samples change phase, and increases the synchronicity and integrity of real-time analysis detecting of the samples.
Owner:SUN YAT SEN UNIV

Normal-temperature normal-pressure femto-second CARS (Coherent Anti-stokes Raman Spectroscopy) time-resolved spectrum measuring system

The invention relates to a normal-temperature normal-pressure femto-second CARS (Coherent Anti-stokes Raman Spectroscopy) time-resolved spectrum measuring system which relates to the technical field of nonlinear optics and solves the problem of multiple limiting factors of traditional femto-second CARS time-resolved spectrum measuring experiment. Beams output by a femto-second laser are adjusted through a series of reflectors and optical delay lines by the system to form three bundles of beams which have approximate energy and are respectively positioned on three peaks of a square on the vertical direction of the beams, the beams are focused to a sample pool and then emit a new beam along a specific angle, i.e. a CARS signal, the CARS signal is filtered through a filter plate, then received by a probe and input to a monochromator, the data acquisition of an electrical signal converted by a photomultiplier is carried out by utilizing BOCCAR, and the data are input to a computer for data processing. The invention can carry out femto-second CARS time-resolved spectrum measurement under the experimental conditions of normal temperature and normal pressure and is applicable for the femto-second CARS spectrum measurement of gas samples and liquid samples in a static sample pool.
Owner:HARBIN INST OF TECH

Quick changeable temperature small-sized constant temperature sample pool

InactiveCN101281121APrecise and fast temperature controlMeet the requirements of constant temperatureMaterial analysis by optical meansWater/sand/air bathsTemperature controlMetallic materials
The invention relates to a quick variable temperature miniature thermostatic sample cell, which is made of metallic material, an opening is formed in the center of the metallic material and is used as a sample cavity, a light through hole is formed on a metallic shell along the center of the sample cavity, a transparent material is embedded in the light through hole, a Peltier temperature control element is glued on the non-light surface of the metallic material, a groove is arranged on the bottom of the metallic shell for laying aside a temperature sensor, the coat of the metal shell has a heat insulation outer frame, the center of a base connected with the bottom of the heat insulation outer frame is provided with a miniature motor, a small magnet is arranged at the edge of the leaf of a spiral leaf on the shaft of the motor, a stirring magneton is laid aside at the bottom in the sample cavity, the inner wall of the sample cavity and the outer faces of the sensor and the stirring magneton is carried on chemical inertia processing. The invention replaces the water heat conduction with the metal, and changes the system temperature with a thermo-element; the sensor directly observes the temperature of the sample, the heat conduction is speeded up by a miniature electromagnetic stirring system has accelerated; the invention is characterized in having small volume, accurate the temperature measurement, quick variable temperature, and good stability, etc, being able to be placed in analytical instrument such as spectrophotometer, etc., and realizing the quick variable temperature and the accurate thermostatic control of the temperature of the sample.
Owner:SHANGHAI JIAO TONG UNIV
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