The invention relates to a surface plasmon resonance imaging sensing system, which comprises a plasma resonator with isosceles triangle cross-section, wherein the plane of the bottom side of the isosceles triangle is of a sensing plane, and a layer of metal reflection film is plated on the sensing plane; a sample pool with an inlet and an outlet is arranged on the metal reflection film, and one of the planes of the two sides of equal length is used as an incident plane, and the other thereof is used as an emittance plane; a power source, a beam shaper and a polarizer are sequentially arranged on an incident light path which is vertical to the incident plane to reach the sensing plane, and an analyzer, an imaging lens group and an area array photoelectric sensor are sequentially arranged on a reflection light path generated by the sensing plane; and the area array photoelectric sensor is positioned on a focal plane of the imaging lens group and is connected with an external computer. The surface plasmon resonance imaging sensing system is characterized in that: the light source is a non-coherent light source, and a narrow-band filter is arranged between the polarizer and the incident surface. The invention can be widely used in food safety detection, pesticide residue detection, bio-molecule detection, bio-terrorist detection and other fields.