Integrated micro-fluidic chip

A technology of microfluidic chips and substrates, which is applied in the fields of biology, medical testing, and chemical analysis, and can solve the problems of difficult sample flow in microfluidic chips

Active Publication Date: 2017-11-28
CAPITALBIO CORP
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, in actual use, it was found that because the residual air in the channel was compressed and the air pressure increased, all the samples in the sample cell could not flow smoothly into the mixing cell, and the liquid in the mixing cell could not flow smoothly into the reaction cell. , the sample flow throughout the microfluidic chip is very difficult

Method used

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Embodiment Construction

[0045] The core of the present invention is to provide an integrated microfluidic chip, so as to ensure that the sample flows smoothly in the predetermined channel of the microfluidic chip, and finally make the sample generate the target product.

[0046] In order to enable those skilled in the art to better understand the solution of the present invention, the present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0047] In the integrated microfluidic chip disclosed in the present invention, at least one integrated reaction unit is arranged on the substrate 16, and the integrated reaction unit includes at least a sample pool 1, a mixing pool 2 and a reaction pool 3, wherein the sample pool 1 is For the temporary storage of samples, the mixing pool 2 is a place for mixing the sample with other substances that need to be mixed, and the reaction pool 3 is the place where the sample finally reacts and g...

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Abstract

The invention relates to an integrated micro-fluidic chip. At least one integrated reaction unit is arranged on a substrate and at least comprises a sample tank, a mixing tank and a reaction tank which are communicated through a liquid channel, and a sample inlet is formed in one end of the sample tank; and the integrated reaction unit further comprises a gas circuit internal cycle system, one end of the gas circuit internal cycle system is connected with the mixing tank, and the other end of the gas circuit internal cycle system at least comprises a first cycle branch connected with one end, far from the sample inlet, of the sample tank. According to the integrated micro-fluidic chip, the air pressure balance in the sample tank and the mixing tank is guaranteed, so that the smooth flow of a sample in a predetermined channel of the micro-fluidic chip is guaranteed, and a reliable foundation is provided for generating a target product from the sample.

Description

technical field [0001] The invention relates to the fields of biology, medical examination and chemical analysis, in particular to an integrated microfluidic chip. Background technique [0002] Microfluidic chip technology integrates the basic operation units of sample preparation, reaction, separation and detection in the biological and chemical medical analysis process into a micron-scale chip, and automatically completes the whole analysis process. [0003] The microfluidic chip is the main platform for the realization of microfluidic technology. The main feature of its device is that its effective structure (channels, reaction chambers and other functional components) to accommodate fluids is at least on a latitude of micron scale. The microfluidic chip has There are many advantages such as controllable liquid flow, minimal consumption of samples and reagents, and fast analysis speed. [0004] A microfluidic chip is usually equipped with a sample pool, a mixing pool, an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00G01N35/00
CPCB01L3/5027G01N35/00B01L2200/10G01N1/38G01N21/07G01N21/272G01N21/76G01N21/82B01L2200/0605B01L2300/0803B01L2300/0864B01L2300/0867B01L2400/0409G01N2021/0328G01N2021/6482B01L3/502723B01L2200/0684B01L2400/0688B01L2300/087B01L2300/161B01F33/30B01F35/71725B01F2101/23B01F2101/2202B01L3/502707B01L2300/0887
Inventor 王磊周峣邢婉丽王虎程京陈翔林明仙
Owner CAPITALBIO CORP
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