870results about How to "Control rate" patented technology

The invention provides methods for sequencing a polynucleotide comprising stopping an extension cycle in a sequence by synthesis reaction before the reaction has run to near or full completion.

Implantable devices and methods for delivering drugs and other substances to locations within the body of a human or animal subject to treat or diagnose sinusitis and a variety of other disorders. The invention includes implantable substance delivery devices that comprise reservoirs and barriers that control the rate at which substances pass out of the reservoirs. The delivery devices may be advanced into the body using guidewires, catheters, ports, introducers and other access apparatus. In some embodiments the delivery devices may be loaded with one or more desired substance before their introduction into the body. In other embodiments the delivery devices are loaded and / or reloaded with a desired substance after the delivery device has been introduced into the body.

Mechanisms, assemblies, systems, tools, and methods incorporating the use of an offset drive shaft within an independently rotating member are provided. An example mechanism includes a base and a main shaft mounted to rotate relative to the base, a first drive shaft mounted inside the main shaft, and a first drive feature engaged with the first drive shaft. The main shaft includes a proximal end, a distal end, and a main shaft rotational axis defined therebetween. The first drive shaft is offset from the main shaft rotational axis. A first drive feature rotational axis is defined for the first drive feature and is fixed relative to the base as the main shaft rotates. The first drive feature rotates the first drive shaft.

An adaptive alarm system is responsive to a physiological parameter so as to generate an alarm threshold that adapts to baseline drift in the parameter and reduce false alarms without a corresponding increase in missed true alarms. The adaptive alarm system has a parameter derived from a physiological measurement system using a sensor in communication with a living being. A baseline processor calculates a parameter baseline from a parameter trend. Parameter limits specify an allowable range of the parameter. An adaptive threshold processor calculates an adaptive threshold from the parameter baseline and the parameter limits. An alarm generator is responsive to the parameter and the adaptive threshold so as to trigger an alarm indicative of the parameter crossing the adaptive threshold. The adaptive threshold is responsive to the parameter baseline so as to increase in value as the parameter baseline drifts to a higher parameter value and to decrease in value as the parameter baseline drifts to a lower parameter value.

The invention provides methods for sequencing a polynucleotide comprising stopping an extension cycle in a sequence by synthesis reaction before the reaction has run to near or full completion.

An adaptive alarm system is responsive to a physiological parameter so as to generate an alarm threshold that adapts to baseline drift in the parameter and reduce false alarms without a corresponding increase in missed true alarms. The adaptive alarm system has a parameter derived from a physiological measurement system using a sensor in communication with a living being. A baseline processor calculates a parameter baseline from a parameter trend. Parameter limits specify an allowable range of the parameter. An adaptive threshold processor calculates an adaptive threshold from the parameter baseline and the parameter limits. An alarm generator is responsive to the parameter and the adaptive threshold so as to trigger an alarm indicative of the parameter crossing the adaptive threshold. The adaptive threshold is responsive to the parameter baseline so as to increase in value as the parameter baseline drifts to a higher parameter value and to decrease in value as the parameter baseline drifts to a lower parameter value.

A computer graphics display system such as a video game system provides virtual camera 3-D viewpoint panning control based on a pointer. When the pointer is displayed within a virtual camera panning control region, the system automatically pans the virtual camera toward the pointer. When the pointer is displayed within a different region, panning is deactivated and the user can freely move the cursor (e.g., to control the direction a weapon is pointed) without panning the virtual camera viewpoint. Flexible viewpoint control and other animated features are provided based on a pointing device such as a handheld video game optical pointing control. Useful applications include but are not limited to first person shooter type video games.

A foamable composition, includes (1) about 6% to about 70% by weight of at least one organic carrier; (2) about 0.1% to about 5% by weight of at least one surface-active agent; (3) about 0.01% to about 5% by weight of at least one film forming agent; (4) water; and (5) about 3% to about 25% by weight of the total composition of at least one liquefied or compressed gas propellant. The composition is substantially alcohol free and is used in treating, alleviating or preventing a disorder.

A network device coordinates with other devices in a network to create a distributed filtering system. The device detects an attack in the network, such as a distributed denial of service attack, and forwards attack information to the other devices. The devices may categorize data into one or more groups and rate limit the amount of data being forwarded based on rate limits for the particular categories. The rate limits may also be updated based on the network conditions. The rate limits may further be used to guarantee bandwidth for certain categories of data.

A method of forming particles comprises accelerating a stream comprising a liquid; and vibrating the stream, to form particles. The particle may have a diameter that is smaller than the diameter of the nozzle used to form the stream, allowing for the formation of micro- and nano-sized particle.

Disclosed herein is a method of operating a polymerization reactor for a polymerization reaction comprising modifying a recycle gas composition to increase the heat capacity of the recycle gas wherein the recycle gas composition is modified by reducing or eliminating the nitrogen concentration in the recycle gas. In an embodiment, the nitrogen concentration is reduced or eliminated by reducing or eliminating one or more nitrogen input sources to the polymerization reactor and replacing the nitrogen with an alternate inert fluid (a gas or liquid that is inert to the catalyst and reactants). The alternate inert fluid has a higher heat capacity and a higher molecular weight than nitrogen. In an embodiment, the nitrogen utilized to convey a catalyst into the polymerization reactor is replaced with an alternate inert fluid. In an embodiment, the alternate inert fluid is ethane, propane, isobutane, or combinations thereof.

A method of stimulating coalbed methane production by injecting gas into a producer and subsequently placing the producer back on production is described. A decrease in water production may also result. The increase in gas production and decrease in water production may result from: (1) the displacement of water from the producer by gas; (2) the establishment of a mobile gas saturation at an extended distance into the coalbed, extending outward from the producer; and (3) the reduction in coalbed methane partial pressure between the coal matrix and the coal's cleat system.

A device for the administration of basic active agents, such as nicotine, to the human or animal body. The active agents are administered by inhalation. The device comprises a first preparation containing a nicotine base or / and a further basic active agent and, a second or further preparations. At least one preparation contains at least one volatile acid suitable for inhalation.

An adaptive communication system utilises opportunistic peak-mode transmissions to transmit data between originating and destination stations, via one or more intermediate stations. Each station monitors the activity of other stations in the network, storing connectivity information for use in subsequent transmissions. Each station also sends out probe signals from time to time, to establish which other stations are in range. Messages are then sent across the network from station to station, with confirmation data being transmitted back to the originating station, until the destination station is reached. Old messages, which would otherwise clog the network, are timed out and deleted. A communication network and transceiver apparatus for use in the network are also disclosed.

A medical treatment system and method of treatment is described having an implant that can be positioned and deployed, then undeployed to allow repositioning of the implant. The system includes a self-expanding medical implant that longitudinally foreshortens upon radially expanding from a radially compacted state, a distal interface configured to attach the implant to a distal mount of a delivery device, and a proximal interface configured to attach the implant to a proximal mount of the delivery device. Moving the distal mount longitudinally away from the proximal mount applies a longitudinal tension to the implant causing the implant to expand longitudinally and contract radially, and moving the distal mount toward the proximal mount reduces a longitudinal tension in the implant allowing the implant to expand radially toward a fully expanded state.

A fin cover release and deployment system designed for high G forces of gun-launched missiles. In one embodiment, a pyrotechnic actuator drives actuator arms to first release and eject the fin slot covers, followed by deployment of the fins radially outward to the steering position. Following complete ejection of the covers, the fins are driven outwardly by cam surfaces along the latch arms, followed by a spring and wedge mechanism installed interiorly of the fin steering shaft to lock the fins in the fully deployed state. In another embodiment, a motor and rotating threaded shaft replace the pyrotechnic actuator.

Heart treatment equipment and a heart treatment method directed to prevention of a fatal arrhythmia by detecting a physical exercise or a mental stress by using a sensor and thereafter controlling the vagus nerve stimulation, wherein sensor means for detecting various living body information for generating a signal which designates degree of a sympathetic tone is provided and heart rate threshold for carrying out the vagus nerve stimulation is adjusted according to the living body information detected by the sensor means. Further, a nerve stimulation parameter for adjusting the strength of the vagus nerve stimulation is adjusted in response to the degree of the patient sympathetic tone.

Congestion in a radio access network (RAN) associated with transporting uplink information originating from one or more mobile terminals is detected. That detected RAN congestion is reduced using any suitable technique (several examples are described) and may be implemented in one or more nodes in the RAN. One advantageous (but non-limiting) application is to a RAN that supports high speed uplink packet access (HSUPA) and / or one or more enhanced uplink dedicated channels (E-DCHs).

A method and system for controlling traffic on a network. A congestion indicator is generated by network components in response to the flow of network traffic. The congestion indicator is received by a network peripheral node that has a threshold variable which controls the flow of traffic flowing from the network peripheral node. The threshold variable corresponding to the congestion indicator will be reduced in order to restrict the flow of traffic flowing from that network peripheral node. If more than one congestion indicator is received by the network peripheral node, then the threshold variable will continue to be reduced thereby further restricting network traffic. If no further congestion indicators are received, then the network peripheral node will terminate the Back-Off Period state of the threshold variable such that the threshold variable can then be increased and network traffic can increase.

Dental bleaching compositions are made with a bleaching agent and a stable radiant-energy absorbing compound that acts as a bleaching agent activator. The dental bleaching compositions of the present invention can be one-part, pre-mixed compositions that do not require mixing at the time of treating a patient's teeth but which remain stable over time. The bleaching agent may consist of hydrogen peroxide, either in aqueous form or complexed with urea (carbamide peroxide) or sodium perborate. The bleaching agent activator includes hydrocarbons that are stable in the presence of the bleaching agent, which do not prematurely accelerate liberation of the bleaching agent, but which allow for selective activation of the bleaching agent by irradiation of the bleaching composition with radiant energy. The bleaching composition may optionally include a neutralizing agent to adjust the pH, a carrier to help provide proper consistency and potency, and a stabilizing agent to maintain maximum potency of the bleaching agent over time. The bleaching composition may also include a thickening agent to achieve a selected viscosity. The dental bleaching compositions may be adapted to be loaded into and delivered from a syringe.

Therapeutic agent delivery formulations for the sustained release of therapeutic agents from a Port Delivery System (PDS) implant is described in this application.

A source and / or method of generating quantum-correlated and / or entangled photon pairs using parametric fluorescence in a fiber Sagnac loop. The photon pairs are generated in the 1550 nm fiber-optic communication band and detected by a detection system including InGaAs / InP avalanche photodiodes operating in a gated Geiger mode. A generation rate>103 pairs / s is observed, a rate limited only by available detection electronics. The nonclassical nature of the photon correlations in the pairs is demonstrated. This source, given its spectral properties and robustness, is well suited for use in fiber-optic quantum communication and cryptography networks. The detection system also provides high rate of photon counting with negligible after pulsing and associated high quantum efficiency and also low dark count rate.

The present invention concerns the use of compounds that interfere with the hedgehog signaling pathway for the manufacture of a medicament for preventing, inhibiting, and / or reversing ocular diseases related with ocular neovascularization. Particularly, the above-mentioned diseases are (wet) age-related macular degeneration, (proliferative) diabetic retinopathy, neovascular glaucoma, retinal vein occlusion, or retinopathy of prematurity (ROP).

Thermoplastic polyurethanes having an alternating sequence of hard and soft segments in which a nanostructured polyhedral oligosilsesquioxane diol is used as a chain extender to form a crystalline hard segment constituting SMPs. The polyurethanes are formed by reacting a polyol, a chain extender dihydroxyl-terminated polyhedral oligosilsesquioxane and a diisocyanate. The polyurethanes have multiple applications including for example, implants for human health care, drug delivery matrices, superabsorbant hydrogels, coatings, adhesives, temperature and moisture sensors, etc.

Controlling the transformation of the microstructure of shape memory material implants. A surgeon can use the inventive energy delivery device to control the rate of implant shape change, the extent of implant shape change, as well as the force exerted on the surrounding tissue. The invention allows for the fine control of force when fixating osteoporotic bone and rate of bone transport. This system models or measures the heating profile of the implant and provides the surgeon a method to control the extent of microstructure phase transformation so that the rate, force or extent of tissue movement can be controlled individually or together.

The present invention relates to polymeric nanoparticles, particularly useful in drug and agent delivery, as well as for imaging and diagnosis. The polymeric nanoparticles of the present invention comprise cross-linkers that, when degraded, leave simple linear polymeric molecules that can be excreted by the body. The present invention also relates to methods of producing the polymeric nanoparticles of the present invention, and methods of using them in drug and agent delivery, as well as imaging and diagnosis.

A method for vaporizing organic materials and condensing them onto a surface to form a layer, comprising: providing a quantity of organic material in a powdered form in a first container; fluidizing the organic material in the first container and transferring such fluidized material to an auger structure; and rotating at least a portion of the auger structure to transfer fluidized powder from the first container along a feeding path to a vaporization zone where such powder is vaporized and delivered to the substrate to form the layer.