Inhaler for basic pharmaceutical agents and method for the production thereof

Inactive Publication Date: 2007-03-22
LTS LOHMANN THERAPIE-SYST AG
View PDF15 Cites 155 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0041] In a further preferred embodiment, the inhalation device is covered, after production thereof, with a peelable protective layer impermeable to the basic agent(s). This protective layer will be removed only shortly before use, by the user himself By means of the protective layer which has been applied a compartment containing the basic active substance(s), and a

Problems solved by technology

The latter nicotine inhaler is, however, not widely used since with this device only small amounts of nicotine become effective when inhaling.
This is due, in particular, to fundamental deficiencies of the known inhaler technologies and the tolerance that can be achieved with these technologi

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Inhaler for basic pharmaceutical agents and method for the production thereof
  • Inhaler for basic pharmaceutical agents and method for the production thereof
  • Inhaler for basic pharmaceutical agents and method for the production thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0059]FIG. 1A shows a device (1) according to the invention in its commercial form (sectional representation). Device 1 is formed by an outer wall (2) and has two air flow channels (a, b) which, approximately in the middle thereof, expand to form a respective one of the chambers (3a, 3b) and thereafter combine to form an air escape channel (7).

[0060] In the chambers (3a, 3b) there is a nicotine-containing preparation (5) and an acid-containing preparation (4), respectively.

[0061]FIG. 1A shows the condition of the device prior to use. The inlet and outlet orifices of the air flow channels (a, b) are still closed, and the chambers (3a, 3b) are separated from each other by membranes (13) so that mixing of the two components (4, 5) cannot yet take place.

[0062]FIG. 1B shows (likewise in longitudinal section) the device shown in FIG. 1A in the operative condition after opening of the membranes (13) (e.g. by action of heat or by pushing through) and of the inlet and outlet apertures (A,...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

A device for the administration of basic active agents, such as nicotine, to the human or animal body. The active agents are administered by inhalation. The device comprises a first preparation containing a nicotine base or/and a further basic active agent and, a second or further preparations. At least one preparation contains at least one volatile acid suitable for inhalation.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS [0001] This application is a National Stage application of International Application No. PCT / EP2004 / 012947, filed on Nov. 16, 2004, which claims priority of German application number 103 56 925.1, filed on Dec. 5, 2003. BACKGROUND OF THE INVENTION [0002] 1. Field of the Invention [0003] The invention relates to devices for administering basic active agents, in particular nicotine, to the human or animal body by inhalation. The invention further relates to methods for producing such devices, as well as the use of such devices for smoking cessation or for smokeless satisfaction of the craving for nicotine in cases of situational necessity. [0004] 2. Description of the Prior Art [0005] Nicotine inhalers for administration of nicotine via the air inhaled during inspiration have been known for several years (e.g. U.S. Pat. No. 4,917,120 and U.S. Pat. No. 5,167,242). For some years nicotine inhalers have also been available on the market as smoking ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A24F47/00A24F42/20A24F42/60A24F42/80A61K9/00A61M15/00A61M15/06
CPCA24F47/002A61M15/0003A61M15/06A61K9/007A61P25/34A24F42/80A24F42/20A24F42/60
Inventor HORSTMANN, MICHAELSCHMITZ, CHRISTOPHLUDWIG, KARINSAMETI, MOHAMMADPRYZBYLLA, YVES-THORSTEN
Owner LTS LOHMANN THERAPIE-SYST AG
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap