100results about "Reagent containers" patented technology

The PCR plate according to the present invention includes: a body portion having one or more reaction wells; an insertion portion extending from the body portion, inserted into a nucleic acid extraction cartridge, and having an injection port into which a nucleic acid solution is injected; a flow path portion allowing the nucleic acid solution to flow from the injection port to the reaction wells; and a blocking portion attached to the body portion for blocking backflow of the nucleic acid solution from the reaction wells to the flow path portion side.

Described herein are systems, methods, and devices for pathogen identification. The system includes a housing configured to receive a sample containing a pathogen, a pipetter system disposed within the housing, a centrifuge disposed within the housing, a mechanical agitator disposed within the housing, and a controller. The controller is configured to transfer the sample to a processing tube using the pipetter system, centrifuge the processing tube using the centrifuge to concentrate the pathogens in the sample, remove liquid from the processing tube using the pipetter system to leave the concentrated pathogens in the processing tube, add a lysis buffer to the processing tube using the pipetter system, move the processing tube to a mechanical agitator using the pipetter system, and agitate the processing tube using the mechanical agitator to lyse the concentrated pathogens. The system is further configured to perform PCR using nucleic acids extracted from the sample.

Implementations include systems for sequencing a biological sample. The systems can include a reusable subsystem and a removable subsystem. The reusable subsystem can actuate and operate the removable subsystem to automate sequencing. A base unit of the reusable subsystem can form a fluidic connection between an integrated reagent cartridge and an integrated sensor cartridge of the removable subsystem. The integrated reagent cartridge can be configured to hold reagents and the integrated sensor cartridge can be configured with a biosensor for sequencing the biological sample.

To provide a suitable fluid container management system. [Solution] A system and method for transporting a container (100) includes or employs a container loading interface (200), a container storage module (400), and a container distributor (300) configured to transport a container from the container loading interface to the container storage module. The container loading interface includes a movable support platform (202) that can move between an accessible position and an inaccessible position, and a container loading carrier (214). The container storage module includes a housing (402) and a container storage carrier (418). The container distributor includes a container gripper (320) configured to grasp a container onto the container loading carrier and transport the container to the container storage carrier in the container storage module.

A system for compounding precise amounts of fluid from one or more source containers into at least one target container is described. The fluid can be drawn from the one or more source containers via an intermediate measuring container such as a syringe pump actuated by a stepper motor or other electronic motor. A system controller can use a measured back EMF value of the motor to determine a pressure within a syringe pump, and control the operation of the motor based at least in part on the determined pressure. The determined pressures of a plurality of syringe pumps can be used to optimize the speed at which the syringe pumps dispense fluid from the source containers while avoiding an overpressure condition which can compromise a compounding process and damage one-way valves within the system.

The present invention relates to the field of biological sample testing technology, and in particular, to a testing system. The testing system includes a reagent reaction vessel and a test device. A reagent storage portion and a push rod movable relative to the reagent storage portion are packaged in the reagent reaction vessel, the reagent storage portion comprises at least one reagent containing cavity, and the reagent containing cavity is sealed by a sealing element; and the push rod is connected to the sealing element, and the push rod is used for cooperation with the test device to separate the sealing element from the reagent storage portion. The test device includes a test cassette, wherein an ejection rod is arranged in the test cassette, and the ejection rod cooperates with the push rod to separate the sealing element from the reagent storage portion. According to the present invention, when the reagent storage portion is inserted, the ejection rod can be quickly pushed to operate, and one operation completes multiple functions such as releasing the reagent, fixing the reagent reaction vessel, and focusing on a test area at the same time, thereby simplifying the reaction steps.

The present invention is directed to a cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, in particular a blood sample, comprising a cartridge body having at least one measurement cavity formed therein and having at least one probe element arranged in said at least one measurement cavity for performing a test on said sample liquid; and a cover being attachable on said cartridge body; wherein said cover covers at least partially said at least one measurement cavity and forms a retaining element for retaining said probe element in a predetermined position within said at least one measurement cavity. The invention is directed to a measurement system and a method for measuring viscoelastic characteristics of a sample liquid.

There is described an assembly for handling biological material, including a first biological handling element, with a first volume having a first port, and a second biological handling element, with a second volume having a second port. The assembly also includes an aseptic connecting element, for aseptically fluidly connecting the first port and the second port, and an aseptic disconnecting element, for aseptically fluidly disconnecting the first port and the second port. Further, one or more of the first biological handling element and the second biological handling element are movable to bring their respective ports into registration with one another to allow, in use, aseptic fluid connection and aseptic fluid disconnection.

Provided herein are devices and methods for the rapid processing and analysis of samples. In particular, a small-volume sample (e.g., nucleic acid sample) is exposed to (e.g., contacted with) different temperature zones within a device to process (e.g., amplify) and / or analyze (e.g., quantitate) the sample in an assay.

A system and method are provided that include the steps of hydrating a lyophilized reagent and homogenizing the hydrated reagent under the control of a control circuit that implements a hydration and homogenization protocol. A lyophilized reagent nozzle sipper that includes a distal tip extends into a lyophilized reagent well such that the distal tip does not contact the associated lyophilized reagent, and a specified amount of hydration fluid is automatically aspirated from a corresponding hydration reservoir by a corresponding sipper and dispensed into the lyophilized reagent well based on a hydration and homogenization protocol implemented by the control circuit. The method may also include extending the lyophilized reagent nozzle sipper into the lyophilized reagent well such that the distal tip contacts the hydrated reagent and automatically aspirating and discharging the hydrated reagent based on a hydration and homogenization protocol implemented by the control circuit.

Fluidic systems and reagent carriers suitable for storing reagents in a desired manner are generally provided. In some embodiments, the reagent carrier stores a liquid film containing a solid reagent and / or stores different reagents at different locations. In some embodiments, the fluidic system includes a reagent carrier constrained such that the reagent carrier includes a longitudinal axis positioned within 30° of a vertical axis of the fluid reservoir.

A system for compounding precise amounts of fluid from one or more source containers into at least one target container is described. The fluid can be drawn from the one or more source containers via an intermediate measuring container such as a syringe pump actuated by a stepper motor or other electronic motor. A system controller can use a measured back EMF value of the motor to determine a pressure within a syringe pump, and control the operation of the motor based at least in part on the determined pressure. The determined pressures of a plurality of syringe pumps can be used to optimize the speed at which the syringe pumps dispense fluid from the source containers while avoiding an overpressure condition which can compromise a compounding process and damage one-way valves within the system.

Contamination detection systems, kits, and techniques are described for testing surfaces for the presence of analytes of interest, including hazardous contaminants, while minimizing user exposure to these contaminants. Even trace amounts of contaminants can be detected. A collection device provides a swab that is simple to use, easy to hold and grip, allows the user to swab large areas of a surface, and keeps the user's hands away from the surface being tested. The collection device also includes a test strip, and provides a closed fluid transfer mechanism to transfer the collected fluid from the swab to the test strip while minimizing user exposure to hazardous contaminants in the collected fluid. Contamination detection kits can rapidly collect and detect hazardous drugs, including trace amounts of antineoplastic agents, in healthcare settings at the site of contamination.

The application provides a sample adding device, which comprises a container adapted to contain reagents and comprising a container mouth; a sample adding mechanism arranged at least partially in the container and in communication with the interior and exterior of the container to deliver the reagents in the container to the exterior of the container; an interface mechanism adapted to connect the container mouth and the sample adding mechanism; the interface mechanism comprises an interface penetrating along the axial direction of the container mouth, and a support and a bearing member successively sleeved in the interface; the interface is detachably sleeved on the outer periphery of the container mouth, and there is a gap between the interface and the support to adapt to receiving the side wall of the container mouth; the bearing member is sleeved on the outside of the sample adding mechanism; first and second sealing rings are arranged between the support and the bearing member and between the support and the side wall of the container mouth respectively to seal the connection of the interface mechanism with the sample adding mechanism and the container mouth respectively. By using the application, simple assembly between the container and the sample adding mechanism can be realized, and sealing between the container and the sample adding mechanism can be realized.

Systems and methods for monitoring water of a swimming pool or spa include containers or cartridges with one or more liquid reagents for automatic chemistry analysis of recreational water. The cartridges provide a store or supply of one or more reagents and may be quickly and easily replaced and replenished by a user. The cartridges may be self-sealing when the cartridge is not engaged with the monitoring device.

Provided is a cover member (33, 36, 50) for covering an opening of a sample container in which a liquid sample is to be contained. To accurately collect the liquid sample contained in the sample container while preventing a carryover, the cover member is made of an elastic sheet material and has a slit (331, 361, 511) in an area different from a predetermined area through which a sample-collecting tool for collecting the liquid sample is to be inserted. This cover member can be suitably used as a septum configured to cover an opening of a vial, or as a sheet configured to cover openings of a plurality of wells provided on a microplate.

A container (100) having a first end (102), a second end (104), and a deformable middle portion (106) and a method for manufacturing the container are disclosed. The container has a folded configuration and an unfolded configuration. The first end and the second end are rigid. The container is configured to store cell culture medium powder. Methods and systems (e.g., dispensers) for producing culture medium using the container are also disclosed. TIFF2023549285000002.tif200152

Described herein are methods of transferring liquid from a reagent reservoir using a mechanical liquid handler, the reagent reservoir having a sloped bottom along a width of the reagent reservoir, the sloped bottom defining a shallow end and a deep end of the reagent reservoir, wherein the shallow end is proximate to a first sidewall of the reagent reservoir, wherein the deep end is proximate to a second sidewall of the reagent reservoir opposite the first sidewall.

A system for delivering a plurality of reagents into a closed flow cell includes one or more reservoirs comprising reagents, a pump configured to cause a flow of the plurality of reagents, an aspiration device coupled to a first fluid channel, a closed flow cell having an inlet and an outlet, where the inlet is coupled to an end of the first fluid channel, and a de-bubbler coupled to the first fluid channel upstream of the closed flow cell. The de-bubbler is configured to divert one or more bubbles from the first fluid channel.

Disclosed in the present invention are a chip and an encapsulation method therefor. The chip comprises a first sheet material, a second sheet material, a first encapsulant and a second encapsulant, the second sheet material being disposed opposite the first sheet material, the first encapsulant being disposed between the first sheet material and the second sheet material, a lane being formed in the first encapsulant, and the second encapsulant being disposed around an edge of the lane. In this way, the first encapsulant can form a stable lane for a reagent to perform a biochemical reaction, and the second encapsulant can isolate the first encapsulant from the lane, reducing or preventing the influence of special molecules released by the first encapsulant on the biochemical reaction in the lanes, thereby improving sequencing quality.

Instructions for handling biological material, including: a first biological handling element comprising a first volume having a first connection; a second biological handling element comprising a second volume having a second connection; an aseptic connecting element configured to aseptically fluidically connect the first port and the second port to provide aseptic fluid communication between the first volume and the second volume; an aseptic separation element configured to aseptically separate the first and second ports fluidically in order to prevent aseptic fluid communication between the first and second volumes; and one or more robot arms; wherein one or more robot arms are arranged to move the first biological handling element and / or the second biological handling element to align the first port and the second port with each other to enable the aseptic connecting element, when used, to aseptically fluidically connect the first port and the second port, and to enable the aseptic separating element, when used, to aseptically fluidically separate the first port and the second port.

A reagent container includes a base defining a plurality of wells having openings exposed at an upper surface of the base and a tube receptacle. The plurality of wells includes a first set of wells and a second set of wells. Each well of the first set of wells has an opening to a well cylinder and a channel in communication with the well cylinder. The opening has a first portion disposed above the well cylinder and a second portion disposed above the channel. An area of the first portion is greater than an area of the second portion. An angle defined by a tangent of an inner surface of the first portion and the second portion at a junction between the first portion and the second portion is at least 100° and no greater than 180°.

Detection devices, systems, and methods for detecting analytes in fluid samples are provided. The detection devices, systems, and methods can include colorimetric detection for rapidly determining the presence and / or amount of analytes obtained from surfaces contaminated or suspected of being contaminated with the analyte. In one aspect, the detection device includes a sample reservoir in fluid communication with a fluid flow path. The fluid flow path includes a control well downstream of the sample reservoir, a valve assembly downstream of the control well, a reagent well downstream of the valve assembly, and a test well downstream of the reagent well. In one aspect, the reagent well contains a dry reducing agent configured to generate a gas in the presence of a detection dye and an analyte in the fluid sample.

Apparatus for printing onto an outer surface of a sample container, such as sample tubes and other containers for holding samples in an analytical laboratory. The apparatus has a printhead having an electromagnetic radiation source, a sample container holder, and a mechanism to (i) move the sample container outer surface relative to the printhead or (ii) move the printhead relative to the sample container outer surface. The apparatus is configured to maintain a distance between the sample container outer surface and the electromagnetic radiation source so as to provide for non-contact printing.

An electronic diagnostics device can detect and report environmental conditions from manufacture to use. The device can include a reaction chamber configured to receive a biological sample and contain a reaction with the biological sample. A component of the biological sample can be detected based on the reaction. The device can also include one or more environmental sensors, such as a temperature sensor and a humidity sensor, to detect the environmental conditions. A processor can read data from the environmental sensors and compare the measured conditions to specified ranges. If an environmental parameter falls outside the specified range, the processor can disable the device or communicate to a user that the device should not be used to perform a diagnostic test.

To provide a container for use in producing a freeze-dried product, capable of more easily accelerating the freeze-drying.SOLUTION: The container for producing or storing a freeze-dried product, comprises a bottom wall, a side wall, a support that supports a fluid to be freeze-dried to prevent it from contacting the bottom wall, and at least one ventilation hole disposed on the bottom wall or at least on a part of the side wall positioned below the top of the support.SELECTED DRAWING: Figure 2

Disclosed are a fluid chamber capable of controlling storage and supply of a fluid and reducing the entire volume thereof, and a fluid chip module and a fluid chip assembly comprising same. The fluid chamber is to store and transfer a fluid supplied to a fluid chip and comprises: a housing having an accommodation space in which a fluid is accommodated and at least one outlet through which the fluid is discharged; an elastic membrane disposed inside the housing and covering an inner end of the outlet; and at least one needle extending from an inner surface of the housing toward the outlet. When the housing is pressed, the needle passes through the elastic membrane to allow the outlet and the accommodation space to communicate with each other.

To provide a multilayer container.SOLUTION: A multilayer container and a method of forming a multilayer container are described. The multilayer container comprises one or more walls defining a storage region for containing one or more substances therein. Each wall of the multi-layer container comprises a plurality of layers, each layer providing at least one of a barrier for containing one or more substances within the storage region or structural integrity of the multi-layer container. The manufacture of multilayer containers does not form perfluoroalkyl and polyfluoroalkyl materials.SELECTED DRAWING: None